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https://www.readbyqxmd.com/read/28285129/green-tea-flavanols-protect-human-%C3%AE-b-crystallin-from-oxidative-photodamage
#1
Susmitnarayan Chaudhury, Pritam Roy, Swagata Dasgupta
Age related cataract is a major cause of visual loss worldwide that is a result of opacification of the eye lens proteins. One of the major reasons behind this deterioration is UV induced oxidative damage. The study reported here is focused on an investigation of the oxidative stress induced damage to γB-crystallin under UV exposure. Human γB-crystallin has been expressed and purified from E. coli. We have found that epicatechin gallate (ECG) has a higher affinity towards the protein compared to epigallocatechin (EGC)...
March 8, 2017: Biochimie
https://www.readbyqxmd.com/read/28270398/pulmonary-vein-mass-with-extension-to-the-left-atrium-diagnosed-by-echocardiography
#2
Jezreel Labrador Taquiso, Jaime Alfonso Manalo Aherrera, Jose Donato Magno, Eric Oliver Sison
We report a case of a man aged 65 years presenting with chronic cough, haemoptysis and intermittent atrial tachyarrhythmias on ECG. On 2D transthoracic echocardiography, an incidental left atrial mass was seen, initially thought to be a thrombus predisposed by intermittent atrial fibrillation. Transoesophageal echocardiography confirmed that this left atrial mass originated from a fixed, non-homogenous, right superior pulmonary vein mass with an extracardiac extension. Because of this finding, a thorough search for a primary focus lead to the discovery of a contiguous posterior mediastinal mass, which was a round cell neoplasm on histology...
March 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28269145/measuring-pulse-rate-variability-using-long-range-non-contact-imaging-photoplethysmography
#3
Ethan B Blackford, Alyssa M Piasecki, Justin R Estepp
Camera-based measurement of the blood volume pulse via non-contact, imaging photoplethysmography is a very popular approach for measuring pulse rate using a remote imaging sensor. Comparatively less attention has been paid to the usefulness of the method for measuring features of pulse rate variability, and even less focus has been put on the accuracy of any cardiac activity feature that can be achieved at long imager-to-subject distances. In this study, video was recorded from 19 participants, while at rest, at a distance of 25 meters from the imaging sensor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268912/photoplethysmography-derivatives-and-pulse-transit-time-in-overnight-blood-pressure-monitoring
#4
Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic
Overnight continuous blood pressure measurement provides simultaneous monitoring of blood pressure and sleep architecture. By this means, we are able to investigate whether different sleep events are associated to blood pressure fluctuations. In this paper, we used the Pulse Transit Time (PTT) to develop and evaluate functions for measurement of blood pressure. We focused on the first and second derivatives of fingertip Photoplethysmography (PPG) recordings to detect PPG critical points. By applying R wave of ECG and PPG critical points, we created two PTT-based models for estimation of systolic and diastolic blood pressure (SBP and DBP)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268118/the-role-of-early-focused-cardiac-ultrasound-in-a-not-so-typical-presentation-of-takotsubo-cardiomyopathy-a-case-report
#5
Jithin G Varghese, Qurat-Ul-Ain Jelani, Stuart Zarich, Brooks Walsh
BACKGROUND: Focused cardiac ultrasound (FoCUS) can be extremely helpful in identifying unexpected diagnoses that can significantly alter treatment options. The diagnosis of Takotsubo cardiomyopathy (TCM) may be difficult to identify. CASE REPORT: We describe a 47-year-old woman who presented to the emergency department (ED) with atypical features of TCM. Her clinical features included being a premenopausal woman with mild chest pain with a lack of identifiable emotional or physical stressors or significant electrocardiographic changes...
March 3, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28253254/novel-non-invasive-algorithm-to-identify-the-origins-of-re-entry-and-ectopic-foci-in-the-atria-from-64-lead-ecgs-a-computational-study
#6
Erick A Perez Alday, Michael A Colman, Philip Langley, Henggui Zhang
Atrial tachy-arrhytmias, such as atrial fibrillation (AF), are characterised by irregular electrical activity in the atria, generally associated with erratic excitation underlain by re-entrant scroll waves, fibrillatory conduction of multiple wavelets or rapid focal activity. Epidemiological studies have shown an increase in AF prevalence in the developed world associated with an ageing society, highlighting the need for effective treatment options. Catheter ablation therapy, commonly used in the treatment of AF, requires spatial information on atrial electrical excitation...
March 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28245585/a-novel-technique-for-fetal-ecg-extraction-using-single-channel-abdominal-recording
#7
Nannan Zhang, Jinyong Zhang, Hui Li, Omisore Olatunji Mumini, Oluwarotimi Williams Samuel, Kamen Ivanov, Lei Wang
Non-invasive fetal electrocardiograms (FECGs) are an alternative method to standard means of fetal monitoring which permit long-term continual monitoring. However, in abdominal recording, the FECG amplitude is weak in the temporal domain and overlaps with the maternal electrocardiogram (MECG) in the spectral domain. Research in the area of non-invasive separations of FECG from abdominal electrocardiograms (AECGs) is in its infancy and several studies are currently focusing on this area. An adaptive noise canceller (ANC) is commonly used for cancelling interference in cases where the reference signal only correlates with an interference signal, and not with a signal of interest...
February 24, 2017: Sensors
https://www.readbyqxmd.com/read/28238152/myocardial-infarction-in-neonates-a-review-of-an-entity-with-significant-morbidity-and-mortality
#8
REVIEW
Koyelle Papneja, Anthony K Chan, Tapas K Mondal, Bosco Paes
Coronary artery disease is a global problem with high mortality rates and significant residual sequelae that affect long-term quality of life. Myocardial infarction (MI) in neonates is a recognized, uncommon entity, but the incidence and broad spectrum of the disease is unknown and likely underestimated due to limited reporting which in the majority is confined to acute ischemic events. The challenges involve clinical diagnosis which masquerades in the early phase as non-specific symptoms and signs that are commonly found in a host of neonatal disorders...
February 25, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28227374/measuring-pulse-rate-variability-using-long-range-non-contact-imaging-photoplethysmography
#9
Ethan B Blackford, Alyssa M Piasecki, Justin R Estepp, Ethan B Blackford, Alyssa M Piasecki, Justin R Estepp, Ethan B Blackford, Alyssa M Piasecki, Justin R Estepp
Camera-based measurement of the blood volume pulse via non-contact, imaging photoplethysmography is a very popular approach for measuring pulse rate using a remote imaging sensor. Comparatively less attention has been paid to the usefulness of the method for measuring features of pulse rate variability, and even less focus has been put on the accuracy of any cardiac activity feature that can be achieved at long imager-to-subject distances. In this study, video was recorded from 19 participants, while at rest, at a distance of 25 meters from the imaging sensor...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227114/photoplethysmography-derivatives-and-pulse-transit-time-in-overnight-blood-pressure-monitoring
#10
Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic, Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic, Sobhan Salari Shahrbabaki, Beena Ahmed, Thomas Penzel, Dean Cvetkovic
Overnight continuous blood pressure measurement provides simultaneous monitoring of blood pressure and sleep architecture. By this means, we are able to investigate whether different sleep events are associated to blood pressure fluctuations. In this paper, we used the Pulse Transit Time (PTT) to develop and evaluate functions for measurement of blood pressure. We focused on the first and second derivatives of fingertip Photoplethysmography (PPG) recordings to detect PPG critical points. By applying R wave of ECG and PPG critical points, we created two PTT-based models for estimation of systolic and diastolic blood pressure (SBP and DBP)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28209604/birth-size-risk-factors-across-life-and-cognition-in-late-life-protocol-of-prospective-longitudinal-follow-up-of-the-mynah-mysore-studies-of-natal-effects-on-ageing-and-health-cohort
#11
Murali Krishna, G Mohan Kumar, S R Veena, G V Krishnaveni, Kalyanaraman Kumaran, Samuel Christaprasad Karat, Patsy Coakley, Clive Osmond, John R M Copeland, Giriraj Chandak, Dattatray Bhat, Mathew Varghese, Martin Prince, Caroline Fall
INTRODUCTION: For late-life neurocognitive disorders, as for other late-life chronic diseases, much recent interest has focused on the possible relevance of Developmental Origins of Health and Disease (DOHaD). Programming by undernutrition in utero, followed by overnutrition in adult life may lead to an increased risk, possibly mediated through cardiovascular and metabolic pathways. This study will specifically examine, if lower birth weight is associated with poorer cognitive functioning in late life in a south Indian population...
February 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28185680/recurrent-pericarditis
#12
M Imazio, A Battaglia, L Gaido, F Gaita
Recurrent pericarditis is the most troublesome complication of pericarditis occurring in 15 to 30% of cases. The pathogenesis is often presumed to be immune-mediated although a specific rheumatologic diagnosis is commonly difficult to find. The clinical diagnosis is based on recurrent pericarditis chest pain and additional objective evidence of disease activity (e.g. pericardial rub, ECG changes, pericardial effusion, elevation of markers of inflammation, and/or imaging evidence of pericardial inflammation by CT or cardiac MR)...
February 6, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28166774/highly-wearable-cuff-less-blood-pressure-and-heart-rate-monitoring-with-single-arm-electrocardiogram-and-photoplethysmogram-signals
#13
Qingxue Zhang, Dian Zhou, Xuan Zeng
BACKGROUND: Long-term continuous systolic blood pressure (SBP) and heart rate (HR) monitors are of tremendous value to medical (cardiovascular, circulatory and cerebrovascular management), wellness (emotional and stress tracking) and fitness (performance monitoring) applications, but face several major impediments, such as poor wearability, lack of widely accepted robust SBP models and insufficient proofing of the generalization ability of calibrated models. METHODS: This paper proposes a wearable cuff-less electrocardiography (ECG) and photoplethysmogram (PPG)-based SBP and HR monitoring system and many efforts are made focusing on above challenges...
February 6, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28131609/geriatric-syncope-and-cardiovascular-risk-in-the-emergency-department
#14
Nissa J Ali, Shamai A Grossman
BACKGROUND: Syncope is a transient loss of consciousness that is caused by a brief loss in generalized cerebral blood flow. OBJECTIVE: This article reviews the background, epidemiology, etiologies, evaluation, and disposition considerations of geriatric patients with syncope, with a focus on cardiovascular risk. DISCUSSION: Although syncope is one of the most common symptoms in elderly patients presenting to the emergency department, syncope causes in geriatric patients can present differently than in younger populations, and the underlying etiology is often challenging to discern...
January 25, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28127975/heart-rate-variability-as-a-biomarker-for-epilepsy-seizure-prediction
#15
M K Moridani, H Farhadi
OBJECTIVE: Epilepsy is a neurological disorder that causes seizures of many different types. Recent research has shown that epileptic seizures can be predicted by using the electrocardiogrami instead of the electroencephalogram. In this study, we used the heart rate variability that is generated by the fluctuating balance of sympathetic and parasympathetic nervous systems to predict epileptic seizures. METHODS: We studied 11 epilepsy patients to predict the seizure interval...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28117887/electrophysiological-adverse-effects-of-direct-acting-antivirals-in-patients-with-chronic-hepatitis-c
#16
Emanuele Durante-Mangoni, Antonio Parrella, Martina Vitrone, Anna Rago, Pia Clara Pafundi, Gerardo Nigro, Riccardo Utili, Vincenzo Russo
Recently, several cases of symptomatic, sometimes fatal bradycardia during the first days of direct-acting antiviral (DAA) (eg, sofosbuvir [SOF]) administration have been reported. We analyzed in detail electrocardiographic (ECG) changes during SOF- or non-SOF-based chronic hepatitis C (CHC) treatment, specifically focusing on bradyarrhythmias. All 39 consecutive patients treated at our center with any interferon-free regimen between June and December 2015 were included in this study (26 SOF-based therapy vs 13 no-SOF interferon-free regimens)...
January 24, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28113874/fall-prediction-in-hypertensive-patients-via-short-term-hrv-analysis
#17
Rossana Castaldo, Paolo Melillo, Raffaele Izzo, Nicola De Luca, Leandro Pecchia
Falls are a major problem of later life having severe consequences on quality of life and a significant burden in occidental countries. Many technological solutions have been proposed to assess the risk or to predict falls and the majority is based on accelerometers and gyroscopes. However, very little was done for identifying first time fallers, which are very difficult to recognise. This paper presents a meta-model predicting falls using short term Heart Rate Variability (HRV) analysis acquired at the baseline...
March 18, 2016: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28113235/s1-and-s2-heart-sound-recognition-using-deep-neural-networks
#18
Tien-En Chen, Shih-I Yang, Li-Ting Ho, Kun-Hsi Tsai, Yu-Hsuan Chen, Yun-Fan Chang, Ying-Hui Lai, Syu-Siang Wang, Yu Tsao, Chau-Chung Wu
OBJECTIVE: This study focuses on the first (S1) and sec-ond (S2) heart sound recognition based only on acoustic charac-teristics; the assumptions of the individual durations of S1 and S2 and time intervals of S1-S2 and S2-S1 are not involved in the recognition process. The main objective is to investigate whether reliable S1 and S2 recognition performance can still be attained under situations where the duration and interval information might not be accessible. METHODS: A deep neural network (DNN) method is proposed for recognizing S1 and S2 heart sounds...
April 27, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28113191/s1-and-s2-heart-sound-recognition-using-deep-neural-networks
#19
Tien-En Chen, Shih-I Yang, Li-Ting Ho, Kun-Hsi Tsai, Yu-Hsuan Chen, Yun-Fan Chang, Ying-Hui Lai, Syu-Siang Wang, Yu Tsao, Chau-Chung Wu
OBJECTIVE:  This study focuses on the first (S1) and second (S2) heart sound recognition based only on acoustic characteristics; the assumptions of the individual durations of S1 and S2 and time intervals of S1-S2 and S2-S1 are not involved in the recognition process. The main objective is to investigate whether reliable S1 and S2 recognition performance can still be attained under situations where the duration and interval information might not be accessible. METHODS:  A deep neural network (DNN) method is proposed for recognizing S1 and S2 heart sounds...
February 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28113141/seizure-detection-and-neuromodulation-a-summary-of-data-presented-at-the-xiii-conference-on-new-antiepileptic-drug-and-devices-eilat-xiii
#20
REVIEW
Meir Bialer, Svein I Johannessen, René H Levy, Emilio Perucca, Torbjörn Tomson, H Steve White, Matthias J Koepp
The Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII) took place in Madrid, Spain from June 26th to 29th 2016. For the first time, the last day of the conference focused solely on new medical devices and neuromodulation. The current article summarises the presentations of that day, focusing first on EEG- and ECG based methods and devices for seizure detection. These methodologies form the basis for novel cardiac-based methods of vagal nerve and responsive deep brain stimulation that rely on the prediction or early detection of seizures and that are also included in this article...
February 2017: Epilepsy Research
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