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https://www.readbyqxmd.com/read/29713440/social-robotics-in-therapy-of-apraxia-of-speech
#1
José Carlos Castillo, Diego Álvarez-Fernández, Fernando Alonso-Martín, Sara Marques-Villarroya, Miguel A Salichs
Apraxia of speech is a motor speech disorder in which messages from the brain to the mouth are disrupted, resulting in an inability for moving lips or tongue to the right place to pronounce sounds correctly. Current therapies for this condition involve a therapist that in one-on-one sessions conducts the exercises. Our aim is to work in the line of robotic therapies in which a robot is able to perform partially or autonomously a therapy session, endowing a social robot with the ability of assisting therapists in apraxia of speech rehabilitation exercises...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29682238/rate-and-rhythm-control-strategies-for-apraxia-of-speech-in-nonfluent-primary-progressive-aphasia
#2
Bárbara Costa Beber, Monalise Costa Batista Berbert, Ruth Siqueira Grawer, Maria Cristina de Almeida Freitas Cardoso
The nonfluent/agrammatic variant of primary progressive aphasia is characterized by apraxia of speech and agrammatism. Apraxia of speech limits patients' communication due to slow speaking rate, sound substitutions, articulatory groping, false starts and restarts, segmentation of syllables, and increased difficulty with increasing utterance length. Speech and language therapy is known to benefit individuals with apraxia of speech due to stroke, but little is known about its effects in primary progressive aphasia...
January 2018: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29672170/the-boundaries-of-auditory-perception-for-within-word-syllable-segregation-in-untrained-and-trained-adult-listeners
#3
Tayla Brown, Elizabeth Murray, Patricia McCabe
Syllable segregation is among the core diagnostic features of both childhood apraxia of speech and acquired apraxia of speech; however, little is known about the limen of perception of syllable segregation. The purpose of this research was therefore to explore adult listeners' auditory perception of within-word syllable segregation in trained and untrained adult listeners. Two experimental design studies, each with two phases, were conducted. Study one included 40 untrained listeners (aged 18-28 years), and study two included 5 trained listeners (10-25 years of experience)...
April 19, 2018: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/29625432/treating-childhood-apraxia-of-speech-with-the-kaufman-speech-to-language-protocol-a-phase-i-pilot-study
#4
Maryane Gomez, Patricia McCabe, Kathy Jakielski, Alison Purcell
Purpose: A Phase I pilot study was designed to collect preliminary evidence on the use of the Kaufman Speech to Language Protocol (K-SLP; Kaufman, 2014) to treat children with childhood apraxia of speech. We hypothesized that the K-SLP approach would result in more accurate speech production in targeted words, whereas untrained (control) words and speech sounds would remain unchanged. Method: A single-case multiple-baseline across behaviors experimental design was used to see if experimental feasibility could be demonstrated...
April 5, 2018: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/29559079/-verbal-and-oral-dyspraxia-in-children-and-juveniles
#5
Trine Printz, Camilla Slot Mehlum, Gohar Nikoghosyan-Bossen
Childhood apraxia of speech and oral dyspraxia are subtypes of dyspraxia: a neurological motor disorder with absence of neuromuscular deficits. The core impairment is in planning and/or programming spatiotemporal parameters of movement sequences, which results in errors in speech sound production and prosody, or in oral motor movements and gestures. Correct diagnostics and focus on differential diagnoses and co-morbidity are crucial, as treatment differs from other types of speech- and oral motor disorders...
March 19, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29506647/-oral-and-verbal-dyspraxia-in-an-otherwise-healthy-child
#6
Gohar Nikoghosyan-Bossen
In the absence of any known neurological condition, dyspraxia is the inability to plan and execute movement. This case report describes a girl with swallowing difficulties, who was diagnosed with oral dyspraxia, as all other possible explanations had been ruled out. A percutaneous endoscopic gastrostomy was performed at the age of 6.5 months, and as a five-year-old she was still dependent on supplementary nutrition through the tube, even though she had gradually learned to swallow. Her difficulties to correctly pronounce syllables and words were later diagnosed as childhood apraxia of speech, another subtype of dyspraxia...
February 26, 2018: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29497818/-18-f-av-1451-uptake-in-corticobasal-syndrome-the-influence-of-beta-amyloid-and-clinical-presentation
#7
F Ali, J L Whitwell, P R Martin, M L Senjem, D S Knopman, C R Jack, V J Lowe, R C Petersen, B F Boeve, K A Josephs
Corticobasal syndrome (CBS) is a phenotypic manifestation of diverse pathologies, including Alzheimer's disease and 4-repeat tauopathies. Predicting pathology in CBS is unreliable and, hence, molecular neuroimaging may prove to be useful. The aim of this study was to assess regional patterns of uptake on [18 F] AV-1451 PET in CBS and determine whether patterns of uptake differ according to beta-amyloid deposition or differing clinical presentations. Fourteen patients meeting criteria for CBS underwent Pittsburgh Compound B (PiB) and [18 F] AV-1451 PET...
May 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29497747/language-changes-following-combined-aphasia-and-apraxia-of-speech-treatment
#8
Lisa D Bunker, Sandra Wright, Julie L Wambaugh
Purpose: Combined Aphasia and Apraxia of Speech Treatment (CAAST) is a newly developed treatment shown to increase production of accurate content in narrative discourse for persons with aphasia and apraxia of speech. The purpose of this post hoc study was to further describe lexical and morphosyntactic changes associated with changes in content production. Method: Existing probe data from 8 persons with aphasia who had completed CAAST were used to complete analyses of morphosyntactic production, lexical diversity, and novelty of content...
March 1, 2018: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29497746/effects-of-treatment-intensity-on-outcomes-in-acquired-apraxia-of-speech
#9
Julie L Wambaugh, Sandra Wright, Emily Boss, Shannon C Mauszycki, Catharine DeLong, William Hula, Patrick J Doyle
Purpose: This investigation was designed to examine the effects of treatment intensity (i.e., dose frequency) on the outcomes of Sound Production Treatment (SPT) for acquired apraxia of speech. Method: Five men with chronic apraxia of speech and aphasia received both intense SPT (3 hr per day/3 days per week) and nonintense/traditional SPT (SPT-T; 1 hr per day/3 days per week) in the context of single-case experimental designs. Each treatment was applied separately to a designated set of experimental words with 1 treatment applied at a time...
March 1, 2018: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29478192/neural-mechanisms-of-swallowing-dysfunction-and-apraxia-of-speech-in-acute-stroke
#10
Lydia A Trupe, Rachel W Mulheren, Donna Tippett, Argye E Hillis, Marlís González-Fernández
Speech and swallowing utilize overlapping anatomy and are thus inherently related processes. We sought to identify common neural mechanisms between risk of swallowing dysfunction and apraxia of speech (AOS). This was a retrospective analysis using data from a prospectively collected cohort. Left hemisphere stroke patients (68 subjects) tested with the Apraxia Battery for Adults II, a swallow screen, and MRI were included in the study. Main outcome measure was the presence of AOS or aspiration risk after stroke...
February 24, 2018: Dysphagia
https://www.readbyqxmd.com/read/29463886/a-set-of-regulatory-genes-co-expressed-in-embryonic-human-brain-is-implicated-in-disrupted-speech-development
#11
Else Eising, Amaia Carrion-Castillo, Arianna Vino, Edythe A Strand, Kathy J Jakielski, Thomas S Scerri, Michael S Hildebrand, Richard Webster, Alan Ma, Bernard Mazoyer, Clyde Francks, Melanie Bahlo, Ingrid E Scheffer, Angela T Morgan, Lawrence D Shriberg, Simon E Fisher
Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most speech and language impairments remain unexplained at the molecular level. We sequenced whole genomes of nineteen unrelated individuals diagnosed with childhood apraxia of speech, a rare disorder enriched for causative mutations of large effect. Where DNA was available from unaffected parents, we discovered de novo mutations, implicating genes, including CHD3, SETD1A and WDR5...
February 20, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29457556/is-markedness-a-confused-concept
#12
Iris Berent
It is well known that, across languages, certain phonological features are more frequent than others. But whether these facts reflect abstract universal markedness constraints or functional pressures (auditory and articulatory difficulties and lexical frequency) is unknown. Romani, Galuzzi, Guariglia, and Goslin (2017) report that the putative markedness of phonological features captures their order of acquisition and their propensity to elicit errors in patients with an apraxia of speech (but not in phonological aphasia)...
October 2017: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29457554/complexity-of-articulation-planning-in-apraxia-of-speech-the-limits-of-phoneme-based-approaches
#13
Wolfram Ziegler
This report presents evidence suggesting that the phoneme-based approach taken by Romani, Galuzzi, Guariglia, and Goslin (Comparing phoneme frequency, age of acquisition, and loss in aphasia: Implications for phonological universals. Cognitive Neuropsychology, this issue) falls short of capturing the complexity of articulation planning in patients with apraxia of speech. Empirical and modelling data are reported to demonstrate that the apraxic pathomechanism resides in the hierarchical architecture of phonological words rather than in the context-independent properties of phonemes...
October 2017: Cognitive Neuropsychology
https://www.readbyqxmd.com/read/29450502/poor-speech-perception-is-not-a-core-deficit-of-childhood-apraxia-of-speech-preliminary-findings
#14
Jennifer Zuk, Jenya Iuzzini-Seigel, Kathryn Cabbage, Jordan R Green, Tiffany P Hogan
Purpose: Childhood apraxia of speech (CAS) is hypothesized to arise from deficits in speech motor planning and programming, but the influence of abnormal speech perception in CAS on these processes is debated. This study examined speech perception abilities among children with CAS with and without language impairment compared to those with language impairment, speech delay, and typically developing peers. Method: Speech perception was measured by discrimination of synthesized speech syllable continua that varied in frequency (/dɑ/-/ɡɑ/)...
March 15, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29445122/deep-phenotyping-of-speech-and-language-skills-in-individuals-with-16p11-2-deletion
#15
Cristina Mei, Evelina Fedorenko, David J Amor, Amber Boys, Caitlyn Hoeflin, Peter Carew, Trent Burgess, Simon E Fisher, Angela T Morgan
Recurrent deletions of a ~600-kb region of 16p11.2 have been associated with a highly penetrant form of childhood apraxia of speech (CAS). Yet prior findings have been based on a small, potentially biased sample using retrospectively collected data. We examine the prevalence of CAS in a larger cohort of individuals with 16p11.2 deletion using a prospectively designed assessment battery. The broader speech and language phenotype associated with carrying this deletion was also examined. 55 participants with 16p11...
February 14, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29392281/error-consistency-in-acquired-apraxia-of-speech-with-aphasia-effects-of-the-analysis-unit
#16
Katarina L Haley, Kevin T Cunningham, Catherine Torrington Eaton, Adam Jacks
Purpose: Diagnostic recommendations for acquired apraxia of speech (AOS) have been contradictory concerning whether speech sound errors are consistent or variable. Studies have reported divergent findings that, on face value, could argue either for or against error consistency as a diagnostic criterion. The purpose of this study was to explain discrepancies in error consistency results based on the unit of analysis (segment, syllable, or word) to help determine which diagnostic recommendation is most appropriate...
February 15, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29359303/contemporary-approaches-to-the-management-of-post-stroke-apraxia-of-speech
#17
Alexandra Basilakos
Apraxia of speech (AOS) is a motor speech disorder that disrupts the planning and programming of speech motor movements. In the acute stage of stroke recovery, AOS following unilateral (typically) left hemisphere stroke can occur alongside dysarthria, an impairment in speech execution and control, and/or aphasia, a higher-level impairment in language function. At this time, perceptual evaluation (the systematic, although subjective, description of speech and voice characteristics) is perhaps the only "gold standard" for differential diagnosis when it comes to motor speech disorders...
February 2018: Seminars in Speech and Language
https://www.readbyqxmd.com/read/29353121/tau-pet-imaging-with-18f-av-1451-in-primary-progressive-apraxia-of-speech
#18
Rene L Utianski, Jennifer L Whitwell, Christopher G Schwarz, Matthew L Senjem, Nirubol Tosakulwong, Joseph R Duffy, Heather M Clark, Mary M Machulda, Ronald C Petersen, Clifford R Jack, Val J Lowe, Keith A Josephs
Apraxia of speech is a motor speech disorder characterized by combinations of slow speaking rate, abnormal prosody, distorted sound substitutions, and trial-and-error articulatory movements. Apraxia of speech is due to abnormal planning and/or programming of speech production. It is referred to as primary progressive apraxia of speech (PPAOS) when it is the only symptom of a neurodegenerative condition. Past reports suggest an association of PPAOS with primary 4-repeat (4R) tau (e.g., progressive supranuclear palsy, corticobasal degeneration), rather than amyloid, pathology...
February 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29281317/changes-in-movement-transitions-across-a-practice-period-in-childhood-apraxia-of-speech
#19
Maria I Grigos, Julie Case
This study examined changes in speech motor control across a movement transition between sounds within a motor learning task in children with apraxia of speech (CAS) and typical development (TD). It was investigated whether oral articulator movement was refined with practice and whether practice gains generalized to words not included in the practice session. A total of 16 children (ages 5-6) with CAS (n = 8) and TD (n = 8) participated in this study. Novel and real word tokens were produced at three time points...
December 27, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/29228180/longitudinal-structural-and-molecular-neuroimaging-in-agrammatic-primary-progressive-aphasia
#20
Katerina A Tetzloff, Joseph R Duffy, Heather M Clark, Edythe A Strand, Mary M Machulda, Christopher G Schwarz, Matthew L Senjem, Robert I Reid, Anthony J Spychalla, Nirubol Tosakulwong, Val J Lowe, Clifford R Jack, Keith A Josephs, Jennifer L Whitwell
The agrammatic variant of primary progressive aphasia affects normal grammatical language production, often occurs with apraxia of speech, and is associated with left frontal abnormalities on cross-sectional neuroimaging studies. We aimed to perform a detailed assessment of longitudinal change on structural and molecular neuroimaging to provide a complete picture of neurodegeneration in these patients, and to determine how patterns of progression compare to patients with isolated apraxia of speech (primary progressive apraxia of speech)...
January 1, 2018: Brain: a Journal of Neurology
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