Cecilia Bica, Ancuta Jurj, Antonia Harangus, Cristina Ciocan, Alin Moldovan, Oana Zanoaga, Claudia Burz, Manuela Ferracin, Lajos Raduly, Ioana Berindan-Neagoe
Lung cancer remains one of the leading causes of cancer-related deaths worldwide. It is classified into two main histological groups: non-small cell lung cancer (NSCLC) and small cell lung cancer. Improving the outcome of cancer patients could be possible by enhancing the early diagnosis. In the current study, we evaluated the levels of three microRNAs - miR-21-5p, miR-155-5p, and miR-181a-5p in tumor (TT) vs adjacent normal tissue (NT), as well as their expression levels in plasma and extracellular vesicles (EVs) from plasma in lung squamous cell carcinoma (LUSC) male patients vs healthy individuals as means to identify a panel of miRNAs that could serve as novel biomarkers for the diagnosis of LUSC in male patients...
April 1, 2024: Translational Oncology