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https://www.readbyqxmd.com/read/29050435/immune-enhancing-activity-of-phosvitin-by-stimulating-the-production-of-pro-inflammatory-mediator
#1
J H Lee, S H Moon, H S Kim, E Park, D U Ahn, H D Paik
Egg yolk phosvitin is one of the most phosphorylated proteins in nature, and the extraordinarily high concentration of phosphate groups in its structure provides a strong metal-binding ability. Phosvitin is known to possess various functional activities, including metal-chelating, antioxidant, emulsifying, antimicrobial, and cytotoxic activities. However, little is known about the immune-enhancing activity of phosvitin. The objective of this study was to evaluate the immune-enhancing activity of phosvitin in murine RAW 264...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/29048907/open-cell-aerogel-foams-via-emulsion-templating
#2
Nicholas Teo, Sadhan C Jana
Water-in-oil emulsion-templating method is used in this work for fabrication of open cell aerogel foams from syndiotactic polystyrene (sPS). A surfactant-stabilized emulsion is prepared at 60 C-100 C by dispersing water in a solution of sPS in toluene. sPS gel, formed upon cooling of the emulsion to room temperature, locks the water droplets inside the gel. The gel is solvent exchanged in ethanol and then dried under supercritical condition of carbon dioxide to yield the aerogel foams. The aerogel foams show significant fraction of macropores of diameter of a few tens of micrometer, defined as macrovoids that originated from the emulsified water droplets...
October 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29046150/complex-interplay-between-solubilization-digestion-supersaturation-and-absorption-of-poorly-soluble-drugs-with-lipid-based-formulations
#3
Vincent Jannin
Lipid-based formulations (LBFs) can be effective oral drug delivery systems for poorly water-soluble chemical entities, provided they are designed with careful selection of the excipients, based on their role in the delivery system and in relation to the drug properties [1]. LBFs comprise four types of formulations (type I, II, III A and B, IV) containing mixture of oils, surfactants and hydrophilic cosolvents, some of which are able to self-emulsify in contact with the gastrointestinal medium [2]. Key considerations in the selection step must be the series of mechanisms underpinning oral bioavailability enhancement...
October 18, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/29043863/preparation-and-evaluation-of-vinpocetine-self-emulsifying-ph-gradient-release-pellets
#4
Mengqi Liu, Shiming Zhang, Shuxia Cui, Fen Chen, Lianqun Jia, Shu Wang, Xiumei Gai, Pingfei Li, Feifei Yang, Weisan Pan, Xinggang Yang
The main objective of this study was to develop a pH gradient release pellet with self-emulsifying drug delivery system (SEDDS), which could not only improve the oral bioavailability of Vinpocetine (VIN), a poor soluble drug, but reduce the fluctuation of plasma concentration. First, the liquid VIN SEDDS formulation was prepared. Then the self-emulsifying pH gradient release pellets were prepared by extrusion spheronization technique, and formulation consisted by the liquid SEDDS, absorbent (colloidal silicon dioxide), penetration enhancer (sodium chloride), microcrystalline cellulose, ethyl alcohol, and three coating materials (HPMC, Eudragit L30D55, Eudragit FS30D) were eventually selected...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/29037741/influence-of-emulsion-interfacial-membrane-characteristics-on-ostwald-ripening-in-a-model-emulsion
#5
Sung Won Han, Ha Youn Song, Tae Wha Moon, Seung Jun Choi
Ostwald ripening is a major destabilization mechanism for emulsions containing flavor oils with relatively high water solubilities. Emulsions with different oil phase compositions were prepared that were stabilized by polyoxyethylene alkyl ether-type emulsifiers with differently sized hydrophilic and hydrophobic groups. Emulsions prepared using only orange oil were highly unstable to Ostwlad ripening during storage. When emulsifier concentration was increased, Ostawald ripening in emulsions containing emulsifiers with small hydrophilic groups was inhibited, while size increment of droplets in emulsions containing emulsifiers with large hydrophilic groups was not...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037724/nanoemulsion-delivery-system-of-tea-polyphenols-enhanced-the-bioavailability-of-catechins-in-rats
#6
Yunru Peng, Qilu Meng, Jie Zhou, Bo Chen, Junjun Xi, Piaopiao Long, Liang Zhang, Ruyan Hou
Tea polyphenols (TP) were emulsified with corn oil and polysorbate 80 by high-pressure homogenization. The oil in water (O/W) TP nanoemulsion had droplet sizes of 99.42±1.25nm after preparation. The TP nanoemulsion was stable during storage at 4, 25 or 40°C for 20days. An in vitro simulated digestion assay showed that the bioaccessibility of (-)-epigallocatechin gallate (EGCG) was increased in the nanoemulsion compared to that in aqueous solution, but that the bioaccessibilities of (-)-epigallocatechin (EGC), (-)-epicatechin (EC) and (-)-gallocatechin gallate (GCG) were greatly decreased...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037706/lutein-enriched-emulsion-based-delivery-systems-influence-of-emulsifiers-and-antioxidants-on-physical-and-chemical-stability
#7
Fabienne Weigel, Jochen Weiss, Eric Andrew Decker, David Julian McClements
The impact of emulsifier type (quillaja saponin, Tween 80, whey protein and casein) and antioxidant type (EDTA, ascorbic acid, catechin, alpha tocopherol, ascorbic acid palmitate) on the physical and chemical stability of lutein-fortified emulsions was investigated. Quillaja saponin produced emulsions with the best overall stability to droplet aggregation, creaming, and colour fading during storage at 45°C for ten days. The impact of antioxidant type on the stability of lutein-fortified emulsions prepared using quillaja saponin was therefore investigated further...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037703/effects-of-moisture-and-temperature-during-grain-storage-on-the-functional-properties-and-isoflavone-profile-of-soy-protein-concentrate
#8
Valmor Ziegler, Cristiano Dietrich Ferreira, Jéssica Fernanda Hoffmann, Maurício de Oliveira, Moacir Cardoso Elias
The objective of this study was evaluate the effects of moisture and temperature during grain storage on the functional properties and isoflavone profile of soy protein concentrate. The protein concentrate was extracted from soybeans on the first day of storage and after 12months of storage, at 12 and 15% moisture and at temperatures of 11, 18, 25, and 32°C. The protein concentrate obtained from grains stored at 32°C showed decreased extraction yield (51.6% with 15% of moisture) and protein solubility (24...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037669/lipid-composition-and-emulsifying-properties-of-camelina-sativa-seed-lecithin
#9
Henok D Belayneh, Randy L Wehling, Edgar Cahoon, Ozan N Ciftci
There is no information on the chemical composition of camelina seed lecithin; therefore, the objective of this study was to investigate the chemical composition and emulsifying properties of lecithin recovered from camelina seed oil by water (WDCL) and enzymatic degumming (EDCL) using phospholipase A1 (PLA1). The lecithin obtained by both WDLC and EDLC was rich in phosphatidylinositol (PI), and contents were 37.8 and 25.2wt%, respectively. Lecithin recovered by enzymatic degumming contained more lysophospholipids compared to water degumming...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29037249/a-novel-self-micro-emulsifying-delivery-system-smeds-formulation-significantly-improves-the-fasting-absorption-of-epa-and-dha-from-a-single-dose-of-an-omega-3-ethyl-ester-concentrate
#10
Yan Qin, Hilde Nyheim, Else Marie Haram, Joseph M Moritz, Svein Olaf Hustvedt
BACKGROUND: Absorption of EPA and DHA from Omega-3-acid ethyl ester (EE) concentrate supplements occurs most efficiently when taken in context of a fatty meal; adequate fat intake is required to release bile salts that emulsify and pancreatic enzymes that digest omega-3-containing lipids in the intestine. Current guidelines recommend reduction in fat intake and therefore there is a need to optimize the absorption of Omega-3 in those consuming low-fat or no-fat meals. To this end, BASF has developed an Absorption Acceleration Technology, a novel self-micro-emulsifying delivery system (SMEDS) formulation of highly concentrated Omega-3-acid EE which enables rapid emulsification and microdroplet formation upon entering the aqueous environment of the gut therefore enhances the absorption...
October 16, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29034291/microbial-biodiversity-of-tang-and-pirgal-mud-volcanoes-and-evaluation-of-bio-emulsifier-and-bio-demulsifier-activities-of-capnophile-bacteria
#11
Yasaman Parsia, Shahryar Sorooshian
The data presented in this article is related to the Master thesis; entitled "Survey Aerobic Microbial Diversity Mud Volcanoes in Chabahar and Khash Ports in Southern Iran" by the first author of this article, year 2011, Islamic Azad University, Iran (reference number (Parsia, 2011) [1] of this article). This article shows microbial biodiversity and evaluates bio-emulsifier and bio-demulsifier abilities of capnophile isolates, in order to introduce a superior isolate for the Microbial Enhanced Oil Recovery (MEOR) process in the petrochemical industry...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29028574/gravity-directed-separation-of-both-immiscible-and-emulsified-oil-water-mixtures-utilizing-coconut-shell-layer
#12
Jian Li, Changcheng Xu, Yan Zhang, Xiaohua Tang, Wei Qi, Qiong Wang
Pressure-driven and lower flux of superwetting ultrafiltration membranes in various emulsions separation are long-standing issues and major barriers for their large-scale utilization. Even though currently reported membranes have achieved great success in emulsions separeation, they still suffer from low flux and complex fabrication process resulting from their smaller nanoscale pore size. Herein, utilizition of coconut shell as a novel biomaterial for developing into a layer through the simple smashing, cleaning and stacking procedures, which not only could avoid the complexity of film making process, but also could realize efficient gravity-directed separation of both immiscible oil/water mixtures and water-in-oil emulsions with high flux...
September 30, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29025348/safety-assessment-of-diethanolamine-and-its-salts-as-used-in-cosmetics
#13
Monice M Fiume, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of diethanolamine and its salts as used in cosmetics. Diethanolamine functions as a pH adjuster; the 16 salts included in this rereview reportedly function as surfactants, emulsifying agents, viscosity increasing agents, hair or skin conditioning agents, foam boosters, or antistatic agents. The Panel reviewed available animal and clinical data, as well as information from previous CIR reports. Since data were not available for each individual ingredient, and since the salts dissociate freely in water, the Panel extrapolated from previous reports to support safety...
September 2017: International Journal of Toxicology
https://www.readbyqxmd.com/read/29017763/modulating-fat-digestion-through-food-structure-design
#14
REVIEW
Qing Guo, Aiqian Ye, Nick Bellissimo, Harjinder Singh, Dérick Rousseau
Dietary fats and oils are an important component of our diet and a significant contributor to total energy and intake of lipophilic nutrients and bioactives. We discuss their fate in a wide variety of engineered, processed and naturally-occurring foods as they pass through the gastrointestinal tract and the implicit role of the food matrix within which they reside. Important factors that control fat and oil digestion include: 1) Their physical state (liquid or solid); 2) Dispersion of oil as emulsion droplets and control of the interfacial structure of emulsified oils; 3) The structure and rheology of the food matrix surrounding dispersed oil droplets; and 4) Alteration of emulsified oil droplet size and concentration...
October 7, 2017: Progress in Lipid Research
https://www.readbyqxmd.com/read/29016922/morphologic-mechanisms-of-increased-vascular-permeability-of-triolein-emulsion-to-the-blood-brain-barrier
#15
Yuri Sol, Seon Hee Choi, Hak Jin Kim, Yong-Woo Kim, Byung Mann Cho, Hyung Soo Han, Ki J Choi
Triolein emulsion has been known to increase vascular permeability in the brain when it is infused into the carotid artery. The purpose of this study was to identify the morphologic mechanism of increased vascular permeability in brain induced by infusion of emulsified triolein into the carotid artery by transmission electron microscopy (TEM). Triolein emulsion was infused into the carotid artery of rats. TEM using lanthanum tracer was used to evaluate morphologic changes in endothelium with a focus on transcytotic vesicles and tight junction opening...
October 1, 2017: Microscopy
https://www.readbyqxmd.com/read/29016652/optimal-experimental-conditions-for-welan-gum-production-by-support-vector-regression-and-adaptive-genetic-algorithm
#16
Zhongwei Li, Xiang Yuan, Xuerong Cui, Xin Liu, Leiquan Wang, Weishan Zhang, Qinghua Lu, Hu Zhu
Welan gum is a kind of novel microbial polysaccharide, which is widely produced during the process of microbial growth and metabolism in different external conditions. Welan gum can be used as the thickener, suspending agent, emulsifier, stabilizer, lubricant, film-forming agent and adhesive usage in agriculture. In recent years, finding optimal experimental conditions to maximize the production is paid growing attentions. In this work, a hybrid computational method is proposed to optimize experimental conditions for producing Welan gum with data collected from experiments records...
2017: PloS One
https://www.readbyqxmd.com/read/28992507/antimicrobial-edible-coatings-and-films-from-micro-emulsions-and-their-food-applications
#17
Mingming Guo, Madhav P Yadav, Tony Z Jin
This study focused on the use of antimicrobial edible coatings and films from micro-emulsions to reduce populations of foodborne pathogens in foods. Corn-Bio-fiber gum (C-BFG) was used as an emulsifier with chitosan. Allyl isothiocyanate (AIT) and lauric arginate ester (LAE) served as antimicrobials. Micro-emulsions were obtained from a solution consisting of 1% chitosan, 0.5% C-BFG, and 1-4% AIT or LAE which was subject to high pressure homogenization (HPH) processing at 138MPa for 3cycles. Coatings and films produced from the micro-emulsions had micro-pores with sizes ranging from 100 to 300nm and micro-channels that hold antimicrobials effectively and facilitate the release of antimicrobials from the center to the surface of the films or coatings, thus enhancing their antimicrobial efficacy...
October 2, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28991618/optimization-of-transversal-phacoemulsification-settings-in-peristaltic-mode-using-a-new-transversal-ultrasound-machine
#18
Dannen D Wright, Alex J Wright, Tyler D Boulter, Ashlie A Bernhisel, Brian C Stagg, Brian Zaugg, Jeff H Pettey, Larry Ha, Brian T Ta, Randall J Olson
PURPOSE: To determine the optimum bottle height, vacuum, aspiration rate, and power settings in the peristaltic mode of the Whitestar Signature Pro machine with Ellips FX tip action (transversal). SETTING: John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, USA. DESIGN: Experimental study. METHODS: Porcine lens nuclei were hardened with formalin and cut into 2.0 mm cubes. Lens cubes were emulsified using transversal and fragment removal time (efficiency), and fragment bounces off the tip (chatter) were measured to determine optimum aspiration rate, bottle height, vacuum, and power settings in the peristaltic mode...
September 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28990656/optimization-of-saponin-extraction-conditions-with-camellia-sinensis-var-assamica-seed-and-its-application-for-natural-detergent
#19
Wanying Gong, Huang Yewei, Aibing Ji, Wenshu Peng, Cong Liu, Ying Zeng, Ruijuan Yang, Liang Yan, Xuanjun Wang, Jun Sheng
BACKGROUND: The Camellia sinensis var. assamica seed cake (by-product of tea-seed oil) is an abundant resource with poor utilization. The C. sinensis var. assamica seed saponin (CSS) is one kind of nonionic surfactant. In this study, The CSS extraction conditions were optimized by response surface methodology (RSM) and then the CSS detergent was developed. Additionally, the safety and decontamination ability of the developed detergent were evaluated. RESULTS: The optimized extraction conditions were including the extracting temperature of 40...
October 9, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28985066/emulsified-and-liquid-liquid-phase-separated-states-of-%C3%AE-pinene-secondary-organic-aerosol-determined-using-aerosol-optical-tweezers
#20
Kyle Gorkowski, Neil M Donahue, Ryan C Sullivan
We demonstrate the first capture and analysis of secondary organic aerosol (SOA) on a droplet suspended in an aerosol optical tweezers (AOT). We examine three initial chemical systems of aqueous NaCl, aqueous glycerol, and squalane at ∼75% relative humidity. For each system we added α-pinene SOA-generated directly in the AOT chamber-to the trapped droplet. The resulting morphology was always observed to be a core of the original droplet phase surrounded by a shell of the added SOA. We also observed a stable emulsion of SOA particles when added to an aqueous NaCl core phase, in addition to the shell of SOA...
October 18, 2017: Environmental Science & Technology
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