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Dementia severity rating scale

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https://www.readbyqxmd.com/read/27917740/delirium-superimposed-on-dementia-phenomenological-differences-between-patients-with-and-without-behavioral-and-psychological-symptoms-of-dementia-in-a-specialized-delirium-unit
#1
Jennifer Abengaña, Mei Sian Chong, Laura Tay
BACKGROUND: Overlap between neuropsychiatric symptoms of dementia and delirium complicates diagnosis of delirium superimposed on dementia (DSD). This study sought to examine differences in delirium presentation and outcomes between DSD patients with and without pre-existing behavioral and psychological symptoms of dementia (BPSD). METHODS: This was a prospective cohort study of older adults with DSD admitted to a specialized delirium unit (December 2010-August 2012)...
December 5, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27911489/palliative-care-interventions-in-advanced-dementia
#2
REVIEW
Edel Murphy, Katherine Froggatt, Sheelah Connolly, Eamon O'Shea, Elizabeth L Sampson, Dympna Casey, Declan Devane
BACKGROUND: Dementia is a chronic, progressive and ultimately fatal neurodegenerative disease. Advanced dementia is characterised by profound cognitive impairment, inability to communicate verbally and complete functional dependence. Usual care of people with advanced dementia is not underpinned universally by a palliative approach. Palliative care has focused traditionally on care of people with cancer but for more than a decade, there have been increased calls worldwide to extend palliative care services to include all people with life-limiting illnesses in need of specialist care, including people with dementia...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27878969/readiness-for-discharge-from-subacute-mental-health-units-for-older-people-using-available-measures-to-support-clinical-decision-making
#3
Bryan G McMinn, Terry J Lewin, Naveen Savio, Dawn Matters, Carol Smith
Prior to introduction of the Health of the Nation Outcome Scale 65+ (HoNOS65) as a mandated measure, the three subacute mental health units for older people in the present study routinely used the Care Planning Assessment Tool (CPAT) for clinical review and discharge planning. The aims of the present study were to compare these two measures of behavioural change during subacute admissions, to examine associations with discharge readiness, and to assess their overall contributions to discharge planning decisions...
November 23, 2016: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/27877069/risk-factors-and-mortality-associated-with-undertriage-at-a-level-i-safety-net-trauma-center-a-retrospective-study
#4
Chris Barsi, Peter Harris, Rich Menaik, Nicholas C Reis, Swapna Munnangi, Mikhail Elfond
PURPOSE: The primary objective of this study was to determine the risk factors associated with undertriage and the risk factors for mortality among the undertriaged patients at a level I safety-net trauma center. METHODS: A retrospective analysis was performed of all trauma patients who presented to a level I safety-net trauma center with an injury severity score >15 over a 2-year period (2013-2014). Univariate and multivariate regression analyses were used to determine the risk factors predictive of undertriage in major trauma patients (injury severity score >15) and of mortality in undertriaged patients...
2016: Open Access Emergency Medicine: OAEM
https://www.readbyqxmd.com/read/27862654/cerebral-small-vessel-disease-medial-temporal-lobe-atrophy-and-cognitive-status-in-patients-with-ischaemic-stroke-and-transient-ischaemic-attack
#5
F Arba, T Quinn, G J Hankey, M Ali, K R Lees, D Inzitari
BACKGROUND AND PURPOSE: Small vessel disease (SVD) and Alzheimer's disease (AD) are two common causes of cognitive impairment and dementia, traditionally considered as distinct processes. The relationship between radiological features suggestive of AD and SVD was explored, and the association of each of these features with cognitive status at 1 year was investigated in patients with stroke or transient ischaemic attack. METHODS: Anonymized data were accessed from the Virtual International Stroke Trials Archive (VISTA)...
November 14, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27862156/the-physical-environment-activity-and-interaction-in-residential-care-facilities-for-older-people-a-comparative-case-study
#6
Susanna Nordin, Kevin McKee, Maria Wallinder, Lena von Koch, Helle Wijk, Marie Elf
The physical environment is of particular importance for supporting activities and interactions among older people living in residential care facilities (RCFs) who spend most of their time inside the facility. More knowledge is needed regarding the complex relationships between older people and environmental aspects in long-term care. The present study aimed to explore how the physical environment influences resident activities and interactions at two RCFs by using a mixed-method approach. Environmental assessments were conducted via the Swedish version of the Sheffield Care Environment Assessment Matrix (S-SCEAM), and resident activities, interactions and locations were assessed through an adapted version of the Dementia Care Mapping (DCM)...
November 16, 2016: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/27861718/effect-of-cognitively-stimulating-activities-on-symptom-management-of-delirium-superimposed-on-dementia-a-randomized-controlled-trial
#7
Ann Kolanowski, Donna Fick, Mark Litaker, Paula Mulhall, Linda Clare, Nikki Hill, Jacqueline Mogle, Malaz Boustani, David Gill, Andrea Yevchak-Sillner
OBJECTIVE: To determine whether cognitively stimulating activities would reduce duration and severity of delirium and improve cognitive and physical function to a greater extent than usual care. DESIGN: Single-blind randomized clinical trial. SETTING: Eight post-acute care (PAC) facilities. PARTICIPANTS: Community-dwelling older adults with dementia and delirium (N = 283). INTERVENTION: Research staff provided cognitively stimulating activities daily for up to 30 days...
November 12, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27802001/correlation-between-overactive-bladder-symptom-score-and-neuropsychological-parameters-in-alzheimer-s-disease-patients-with-lower-urinary-tract-symptom
#8
Ha Bum Jung, Don Kyoung Choi, Seong Ho Lee, Sung Tae Cho, Hae Ri Na, Moon Ho Park
PURPOSE: To examine an association between the overactive bladder symptom score (OABSS) and neuropsychological parameters. Moreover, we investigate the factors that affect each item in the questionnaire. MATERIALS AND METHODS: A total of 376 patients (males: 184; females: 192) with probable Alzheimer's disease (AD) were recruited. Cognitive testing was conducted using the Mini Mental Status Examination (MMSE), Clinical Dementia Rating (CDR) scale, Global Deterioration Scale (GDS), and Barthel Activities of Daily Living (ADL)...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27787958/-18-f-av-1451-tau-positron-emission-tomography-in-progressive-supranuclear-palsy
#9
Jennifer L Whitwell, Val J Lowe, Nirubol Tosakulwong, Stephen D Weigand, Matthew L Senjem, Christopher G Schwarz, Anthony J Spychalla, Ronald C Petersen, Clifford R Jack, Keith A Josephs
BACKGROUND: The [(18) F]AV-1451 positron emission tomography ligand allows the in vivo assessment of tau proteins in the brain. It shows strong binding in Alzheimer's dementia, but little is known about how it performs in progressive supranuclear palsy, a primary 4R tauopathy. OBJECTIVES: The objectives of this study were to determine whether [(18) F]AV-1451 uptake can be observed in progressive supranuclear palsy and to characterize the regional distribution when compared with controls and Alzheimer's dementia...
October 27, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/27783888/association-of-cortical-microinfarcts-and-cerebral-small-vessel-pathology-in-the-ageing-brain
#10
Enikö Kövari, François R Herrmann, Gabriel Gold, Patrick R Hof, Andreas Charidimou
AIMS: Cortical microinfarcts (CMI) are frequently observed in the ageing brain independent of cognitive decline, but their etiology is not fully elucidated. To examine the potential role of different vessel pathologies, including cerebral amyloid angiopathy (CAA), arteriolosclerosis-hyalinosis, and thromboembolism in the development of CMI, we examined 80 autopsy cases with more than one CMI on routine neuropathological examination. METHODS: Pial and intracortical vessels around CMI were assessed for their integrity with hematoxylin-eosin staining and antibodies against amyloid-β protein and fibrinogen using a semiquantitative 4-level rating scale (absent to severe) in the hippocampus, and the frontal, temporal, and occipital cortex...
October 26, 2016: Neuropathology and Applied Neurobiology
https://www.readbyqxmd.com/read/27755003/modeling-alzheimer-s-disease-through-functional-independence-and-participation
#11
Chiara Zucchella, Michelangelo Bartolo, Sara Bernini, Marta Picascia, Paola Malinverni, Elena Sinforiani
INTRODUCTION: The relationship between cognitive and functional impairment in Alzheimer's Disease (AD) at the earliest stages of the disease is not well characterized. This study aimed at investigating such relationships along AD evolution by means of the Disability Assessment for Dementia (DAD). METHODS: Consecutive pairs of AD outpatients and their primary informal caregivers were enrolled. Patients were evaluated by means of the Mini Mental State Examination and neuropsychological tests...
October 17, 2016: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/27719688/perception-of-change-in-sexual-activity-in-alzheimer-s-disease-views-of-people-with-dementia-and-their-spouse-caregivers
#12
Marcela Moreira Lima Nogueira, Jose Pedro Simões Neto, Maria Fernanda B Sousa, Raquel L Santos, Isabel Barbeito Lacerda, Maria Alice Tourinho Baptista, Marcia Cristina Nascimento Dourado
INTRODUCTION: The onset of Alzheimer's disease (AD) affects couples' relationship. We investigated the perception of change and sexual satisfaction in spouse-caregivers and their partners diagnosed with AD. METHODS: We compared 74 dyads of people with Alzheimer's disease (PwAD)/spouse-caregivers and 21 elderly dyads control. We assessed sexual satisfaction with Questionnaire on Sexual Experience and Satisfaction (QSES), cognition using a Mini-Mental State Examination (MMSE), disease severity using a Clinical Dementia Rating scale (CDR), awareness of disease with Assessment Scale of Psychosocial Impact of the Diagnosis of Dementia (ASPIDD), functionality with Pfeffer Functional Activities Questionnaire (FAQ), depressive symptoms with Cornell Scale for Depression in Dementia (CSDD), quality of life using a Quality of Life in Alzheimer's Disease Scale (QoL-AD), and burden using a Zarit Burden Interview (ZBI)...
October 10, 2016: International Psychogeriatrics
https://www.readbyqxmd.com/read/27711932/behavioral-symptoms-of-dementia-that-present-management-difficulties-in-nursing-homes-staff-perceptions-and-their-concordance-with-informant-scales
#13
Tanya E Davison, Marita P McCabe, Michael Bird, David Mellor, Sarah MacPherson, David Hallford, Melissa Seedy, Daniel W O'Connor
The current study aimed to profile behaviors associated with dementia that pose management difficulties for staff and determine whether existing rating scales capture these reported behaviors. Staff in 17 nursing homes described the behavioral symptoms of 229 residents with predominantly moderate-severe dementia associated with management difficulties. Behaviors were categorized by an expert clinical panel and compared to items in four dementia behavior rating scales. Staff reported 59 discrete behavioral symptoms, with physically agitated, aggressive verbal, non-aggressive verbal, and aggressive physical behaviors most common, followed by resistance to care and inappropriate social and sexual behaviors...
October 5, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27676141/effect-of-visual-impairment-on-physical-and-cognitive-function-in-old-age-findings-of-a-population-based-prospective-cohort-study-in-germany
#14
André Hajek, Christian Brettschneider, Dagmar Lühmann, Marion Eisele, Silke Mamone, Birgitt Wiese, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Steffi G Riedel-Heller, Tobias Luck, Horst Bickel, Dagmar Weeg, Alexander Koppara, Michael Wagner, Martin Scherer, Wolfgang Maier, Hans-Helmut König
OBJECTIVES: To examine how visual impairment affects physical and cognitive function in old age. DESIGN: A longitudinal population-based prospective cohort study. SETTING: General practitioner offices at six study centers in Germany. They were observed every 1.5 years over four waves. PARTICIPANTS: Individuals aged 77-101 at follow-up Wave 2 (N = 2,394). MEASUREMENTS: Physical and cognitive function were assessed using an adapted scale that had been previously developed, and visual impairment was rated on a Likert scale (none, mild, severe or profound)...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27636839/nutritional-status-of-patients-with%C3%A2-alzheimer-s-disease-and-their-caregivers
#15
Mario Tombini, Maura Sicari, Giovanni Pellegrino, Francesca Ursini, Pasqualina Insardá, Vincenzo Di Lazzaro
BACKGROUND: Malnutrition is one of the most important conditions that negatively affects the health of elder people, particularly in patients with dementia. OBJECTIVE: To provide an assessment of nutritional status of patients affected by Alzheimer's disease (AD) living at home and of their caregivers by means of Mini Nutritional Assessment (MNA), and to explore the influence of different factors on nutrition. METHODS: 90 patients affected by AD living at home and 90 age- and sex-matched caregivers were enrolled...
October 18, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27593974/sensitivity-of-the-mini-mental-state-examination-montreal-cognitive-assessment-and-the-addenbrooke-s-cognitive-examination-iii-to-everyday-activity-impairments-in-dementia-an-exploratory-study
#16
Clarissa M Giebel, David Challis
OBJECTIVE: The Mini-Mental State Examination (MMSE) is one of the most frequently used cognitive measures for dementia severity and linked to deficits in everyday functioning. Recently, the Montreal Cognitive Assessment (MoCA) and the Addenbrooke's Cognitive Examination III (ACE-III) increasingly substitute for the MMSE. However, there are no specific cutoffs in the ACE-III for mild dementia. The objectives of this exploratory study were to assess the sensitivity of each scale to everyday functioning and to examine the cutoffs between mild and moderate dementia on the ACE-III...
September 5, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27567838/cerebral-white-matter-changes-on-therapeutic-response-to-rivastigmine-in-alzheimer-s-disease
#17
Bo-Lin Ho, Yi-Hui Kao, Mei-Chuan Chou, Yuan-Han Yang
BACKGROUND: Rivastigmine has been approved in the treatment of Alzheimer's disease (AD) patients as it can inhibit acetyl- and butyryl-cholinesterase and provide neuroprotective effects involving the synapses. White matter changes (WMCs) are frequently observed in AD, and clinical-pathological correlations imply their possible impacts on cognitive function by interference with cortical and subcortical neuronal pathways. OBJECTIVE: To evaluate the therapeutic effects of rivastigmine in AD patients with cerebral WMCs...
August 10, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27472884/all-is-not-lost-positive-behaviors-in-alzheimer-s-disease-and-behavioral-variant-frontotemporal-dementia-with-disease-severity
#18
Akira Midorikawa, Cristian E Leyton, David Foxe, Ramon Landin-Romero, John R Hodges, Olivier Piguet
BACKGROUND: Anecdotal evidence indicates that some patients with dementia exhibit novel or increased positive behaviors, such as painting or singing, after the disease onset. Due to the lack of objective measures, however, the frequency and nature of these changes has not been formally investigated. OBJECTIVE: This study aimed to systematically identify changes in these behaviors in the two most common younger-onset dementia syndromes: Alzheimer's disease (AD) and behavioral-variant frontotemporal dementia (bvFTD)...
September 6, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27417072/frontotemporal-lobar-degeneration-modified-clinical-dementia-rating-ftld-cdr-scale-and-frontotemporal-dementia-rating-scale-frs-correlation-with-regional-brain-perfusion-in-a-series-of-ftld-patients
#19
Pantelis Maiovis, Panagiotis Ioannidis, Georgios Gerasimou, Anna Gotzamani-Psarrakou, Dimitrios Karacostas
Severity assessment scales for frontotemporal lobar degeneration (FTLD) have been recently introduced. In the present study, the authors examined whether the FTLD-modified Clinical Dementia Rating (FTLD-CDR) scale and the Frontotemporal Dementia Rating Scale (FRS) correlated with regional brain perfusion in Greek FTLD patients. A total of 47 behavioral variant frontotemporal dementia (bvFTD) patients and 33 primary progressive aphasia (PPA) patients were assessed for demographic data, cognitive reserve (CR), and severity of dementia and underwent brain single-photon emission computed tomography...
July 15, 2016: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27397011/mutations-in-glucocerebrosidase-are-a-major-genetic-risk-factor-for-parkinson-s-disease-and-increase-susceptibility-to-dementia-in-a-flanders-belgian-cohort
#20
David Crosiers, Aline Verstraeten, Eline Wauters, Sebastiaan Engelborghs, Karin Peeters, Maria Mattheijssens, Peter P De Deyn, Jessie Theuns, Christine Van Broeckhoven, Patrick Cras
OBJECTIVE: To investigate the frequency of glucocerebrosidase (GBA) mutations in a Flanders-Belgian Parkinson's disease (PD) patient cohort and to assess genotype-phenotype correlations. METHODS: We performed an in-depth sequencing of all coding exons of GBA in 266 clinically well-characterized PD patients and 536 healthy control individuals. RESULTS: We identified rare, heterozygous GBA mutations in 12 PD patients (4.5%) and in 2 healthy control individuals (0...
August 26, 2016: Neuroscience Letters
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