Signe Glargaard, Jakob Hartvig Thomsen, Brian Bridal Løgstrup, Morten Schou, Kasper Karmark Iversen, Christian Tuxen, Olav W Nielsen, Christian Axel Bang, Matias Greve Lindholm, Ekim Seven, Anders Barasa, Nis Stride, Søren Vraa, Marlene Tofterup, Rasmus Vedby Rasmussen, Dan Eik Høfsten, Kasper Rossing, Lars Køber, Finn Gustafsson, Jens Jakob Thune
INTRODUCTION: Pleural effusion is present in half of the patients hospitalised with acute heart failure. The condition is treated with diuretics and/or therapeutic thoracentesis for larger effusions. No evidence from randomised trials or guidelines supports thoracentesis to alleviate pleural effusion due to acute heart failure. The Thoracentesis to Alleviate cardiac Pleural effusion Interventional Trial (TAP-IT) will investigate if a strategy of referring patients with acute heart failure and pleural effusion to up-front thoracentesis by pleural pigtail catheter insertion in addition to pharmacological therapy compared with pharmacological therapy alone can increase the number of days the participants are alive and not hospitalised during the 90 days following randomisation...
January 19, 2024: BMJ Open