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https://www.readbyqxmd.com/read/28716370/a-systematic-review-and-framework-for-the-use-of-hormone-therapy-with-salvage-radiation-therapy-for-recurrent-prostate-cancer
#1
REVIEW
Daniel E Spratt, Robert T Dess, Zachary S Zumsteg, Daniel W Lin, Phuoc T Tran, Todd M Morgan, Emmanuel S Antonarakis, Paul L Nguyen, Charles J Ryan, Howard M Sandler, Matthew R Cooperberg, Edwin Posadas, Felix Y Feng
CONTEXT: Salvage radiotherapy (SRT) is a standard of care for men who recur postprostatectomy, and recent randomized trials have assessed the benefit and toxicity of adding hormone therapy (HT) to SRT with differing results. OBJECTIVE: To perform a systematic review of randomized phase III trials of the use of SRT ± HT and generate a framework for the use of HT with SRT. EVIDENCE ACQUISITION: Systematic literature searches were conducted on February 15, 2017 in three databases (MEDLINE [via PubMed], EMBASE, and ClinicalTrials...
July 14, 2017: European Urology
https://www.readbyqxmd.com/read/28691526/non-enhanced-versus-low-dose-contrast-enhanced-renal-magnetic-resonance-angiography-at-7-t-a-feasibility-study
#2
Anja Laader, Karsten Beiderwellen, Oliver Kraff, Stefan Maderwald, Mark E Ladd, Michael Forsting, Lale Umutlu
Background Considering the currently reported association between a repetitive application and cumulative dosage of Gadolinium (Gd)-based contrast agents and Gd-deposition in brain tissue as well as the risk for the advent of nephrogenic systemic fibrosis (NSF), techniques allowing for a dose reduction become an important key aspect aside from non-enhanced magnetic resonance angiography (MRA) techniques. Thus, this study was focused on the reduction and/or complete omission of contrast agent for renal MRA at 7T...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28570867/evoked-potentials-recorded-during-routine-eeg-predict-outcome-after-perinatal-asphyxia
#3
Päivi Nevalainen, Viviana Marchi, Marjo Metsäranta, Tuula Lönnqvist, Sanna Toiviainen-Salo, Sampsa Vanhatalo, Leena Lauronen
OBJECTIVE: To evaluate the added value of somatosensory (SEPs) and visual evoked potentials (VEPs) recorded simultaneously with routine EEG in early outcome prediction of newborns with hypoxic-ischemic encephalopathy under modern intensive care. METHODS: We simultaneously recorded multichannel EEG, median nerve SEPs, and flash VEPs during the first few postnatal days in 50 term newborns with hypoxic-ischemic encephalopathy. EEG background was scored into five grades and the worst two grades were considered to indicate poor cerebral recovery...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28562488/does-obesity-increase-the-risk-of-hot-flashes-among-midlife-women-a-population-based-study
#4
Sylvio Saccomani, Jeffrey Frederico Lui-Filho, Cassia Raquel Juliato, Jose Roberto Gabiatti, Adriana Orcesi Pedro, Lucia Costa-Paiva
OBJECTIVE: To evaluate the association between vasomotor symptoms and obesity in climacteric women. METHODS: We conducted a cross-sectional population-based study of 749 women aged 45 to 60 years. The dependent variable was intensity of menopausal symptoms evaluated by the menopause rating scale questionnaire. Independent variables were sociodemographic and clinical characteristics, and obesity evaluated by body mass index. RESULTS: There was no significant difference in the majority of clinical and sociodemographic characteristics between the body mass index groups...
May 29, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28546818/investigating-the-relationship-between-sexual-function-and-quality-of-life-in-menopausal-women
#5
Masumeh Ghazanfarpour, Talat Khadivzadeh, Masaudeh Babakhanian
Objective: To evaluate the symptoms of menopausal women and the link between sexual function, menopausal symptoms and demographic variables. Materials and methods: This is a cross-sectional study in which 202 postmenopausal women admitted to the health care centers were selected. The Female Sexual Function Index (FSFI) questionnaire and Menopause-Specific Quality of Life (MENQOL) were the main means of data gathering. Results: The results of our study suggested that suggested that women experienced a number of menopausal symptoms such hot flash, headache and neck pains, reduced physical strength weight gain, pain or leg cramps, intensified sexual problem than women who lack such symptoms...
December 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28526365/calibration-and-validation-of-the-youth-activity-profile-the-flashe-study
#6
Pedro F Saint-Maurice, Youngwon Kim, Paul Hibbing, April Y Oh, Frank M Perna, Gregory J Welk
INTRODUCTION: This study describes the calibration and validity of the Youth Activity Profile (YAP) for use in the National Cancer Institute's Family Life, Activity, Sun, Health, and Eating (FLASHE) study. The calibrated YAP was designed to estimate minutes of moderate to vigorous physical activity (MVPA) and sedentary behavior (SB). METHODS: The YAP was calibrated/validated in adolescents (aged 12-17 years) using cross-sectional data from the FLASHE study. Participants wore a GT3X+ ActiGraph on the dominant wrist for 7 days and then completed the YAP...
June 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28509814/validity-cut-points-and-minimally-important-differences-for-two-hot-flash-related-daily-interference-scales
#7
Janet S Carpenter, Giorgos Bakoyannis, Julie L Otte, Chen X Chen, Kevin L Rand, Nancy Woods, Katherine Newton, Hadine Joffe, JoAnn E Manson, Ellen W Freeman, Katherine A Guthrie
OBJECTIVES: To conduct psychometric analyses to condense the Hot Flash-Related Daily Interference Scale (HFRDIS) into a shorter form termed the Hot Flash Interference (HFI) scale; evaluate cut-points for both scales; and establish minimally important differences (MIDs) for both scales. METHODS: We analyzed baseline and postrandomization patient-reported data pooled across three randomized trials aimed at reducing vasomotor symptoms (VMS) in 899 midlife women. Trials were conducted across five MsFLASH clinical sites between July 2009 and October 2012...
May 15, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28508411/the-relationship-between-symptom-prevalence-body-image-and-quality-of-life-in-asian-gynecologic-cancer-patients
#8
Irene Teo, Yin Bun Cheung, Yong Kuei Lim, Namuduri Rama Padmavathi, Victoria Long, Komal Tewani
OBJECTIVE: Gynecologic cancer is associated with long-term effects that can be both physical and emotional. We examined symptom prevalence and body image disturbance in patients with gynecologic cancer, and their association with quality of life. Predictors of clinically-relevant body image disturbance were examined. METHODS: A sample of patients in Singapore (n = 104) was assessed for symptom prevalence, quality of life, and body image dissatisfaction. Clinical factors were extracted from medical records...
May 15, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28472898/the-relation-among-steroid-hormone-levels-lipid-profile-and-menopausal-symptom-severity
#9
Cihan Kaya, Hüseyin Cengiz, Ali Yeşil, Murat Ekin, Levent Yaşar
INTRODUCTION: Many postmenopausal women experience hot flashes, night sweats, non-specific emotional and psychological distresses. Our aim was to investigate the relation among steroid hormone levels, lipid profile and menopausal symptom severity using the menopause rating scale (MRS). METHODS: A cross-sectional study was performed at our outpatient clinic with natural postmenopausal women. A total of 444 women were included in this study. The basic characteristics of the study population, such as age, gravidity, parity, time to menopause onset and body mass index (BMI) were recorded...
May 4, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28404465/tool-for-decision-making-regarding-general-evacuation-during-a-rapid-river-flood
#10
V Radosavljevic, G Belojevic, N Pavlovic
OBJECTIVES: To propose a simple and effective tool for decision-making regarding general evacuation during a rapid river flood. STUDY DESIGN: Virtual testing of a tool in a real event. METHOD: A four-component tool was applied to build an alternative scenario of the catastrophic river flood in Obrenovac, Serbia, on May 2014. The components of this tool are: (1) the amount of precipitation above the 95th percentile of all previous measurements; (2) upstream river discharge above the 95th percentile of all previous measurements; (3) upstream river level above the 95th percentile of all previous measurements; and (4) worsening of the hydrometeorological situation in the following 48 h...
February 23, 2017: Public Health
https://www.readbyqxmd.com/read/28400028/predicting-clinical-and-echocardiographic-response-after-cardiac-resynchronization-therapy-with-a-score-combining-clinical-electrocardiographic-and-echocardiographic-parameters
#11
Anne Bernard, Aymeric Menet, Sylvestre Marechaux, Maxime Fournet, Frederic Schnell, Yves Guyomar, Christophe Leclercq, Philippe Mabo, Laurent Fauchier, Erwan Donal
The L2ANDS2 score was previously found to be able to assess the probability of left ventricular (LV) remodeling. We sought to evaluate this score in terms of clinical outcomes: 275 patients with heart failure, from 2 centers, implanted with a cardiac resynchronization therapy (CRT) device were followed at least 2 years after implantation. Baseline clinical, electrocardiographic, and echocardiographic characteristics including left bundle branch block, age >70 years, nonischemic etiology, LV end-diastolic diameter <40 mm/m(2), and septal flash by echocardiography were integrated in 4 scoring systems...
June 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28364498/sleep-characteristics-and-carotid-atherosclerosis-among-midlife-women
#12
Rebecca C Thurston, Yuefang Chang, Roland von Känel, Emma Barinas-Mitchell, J Richard Jennings, Martica H Hall, Nanette Santoro, Daniel J Buysse, Karen A Matthews
Introduction: Midlife, which encompasses the menopause transition in women, can be a time of disrupted sleep and accelerated atherosclerosis accumulation. Short or poor sleep quality has been associated with cardiovascular disease (CVD) risk; few studies have investigated relations among midlife women. We tested whether shorter actigraphy sleep time or poorer subjective sleep quality was associated with carotid atherosclerosis among midlife women. Aims and Methods: Two hundred fifty-six peri- and postmenopausal women aged 40-60 years completed 3 days of wrist actigraphy, hot flash monitoring, questionnaires (Pittsburgh Sleep Quality Index [PSQI], Berlin), a blood draw, and carotid ultrasound [intima media thickness (IMT), plaque]...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28266949/efficacy-of-a-biobehavioral-intervention-for-hot-flashes-a-randomized-controlled-pilot-study
#13
Debra L Barton, Kelliann C Fee Schroeder, Tanima Banerjee, Sherry Wolf, Timothy Z Keith, Gary Elkins
OBJECTIVE: The need for effective nonhormonal treatments for hot flash management without unwanted side effects continues. The primary aim of this pilot study was to evaluate the effect of combining a nonhormonal pharmacologic agent with a behavioral treatment for hot flash reduction. METHODS: Seventy-one postmenopausal women were randomized to one of four groups: venlafaxine 75 mg + hypnosis (VH) versus venlafaxine 75 mg + sham hypnosis (VSH) versus a placebo pill + hypnosis (PH) versus placebo pill + sham hypnosis (PSH)...
March 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28156437/integrative-oncology-consultation-and-symptom-palliation-analysis-of-patient-reported-outcomes-at-a-comprehensive-cancer-center
#14
Jennifer Leigh McQuade, Richard T Lee, Jane Williams, Amy Spelman, Bryan Fellman, Yisheng Li, Eduardo Bruera, Lorenzo Cohen
84 Background: Patients (pts) receiving cancer care are increasingly interested in complementary health approaches to improve symptoms and quality of life. We report on demographics and patient reported outcomes in an integrative oncology (IO) clinic. METHODS: Pts presenting for IO consultation or follow-up completed: Measure Yourself Concerns and Wellbeing (MYCaW), Edmonton Symptom Assessment Scale (ESAS), Short Form 12 (SF-12) quality of life (QOL) scale, and an overall satisfaction questionnaire...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28094204/microbial-contamination-of-drinking-water-from-risky-tubewells-situated-in-different-hydrological-regions-of-bangladesh
#15
Nepal C Dey, Mahmood Parvez, Digbijoy Dey, Ratnajit Saha, Lucky Ghose, Milan K Barua, Akramul Islam, Mushtaque R Chowdhury
This study, conducted in 40 selected upazilas covering four hydrological regions of Bangladesh, aimed at determining the risk of selected shallow tubewells (depth<30m) used for drinking purpose (n=26,229). This was based on WHO's sanitary inspection guidelines and identifying the association of sanitary inspection indicators and risk scores with microbiological contamination of shallow tubewells. The main objective of the study was to observe the seasonal and regional differences of microbial contamination and finally reaching a conclusion about safe distance between tubewells and latrines by comparing the contamination of two tubewell categories (category-1: distance ≤10m from nearest latrine; n=80 and category 2: distances 11-20m from nearest latrine; n=80) in different geographical contexts...
December 29, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28050507/shear-bond-strength-of-ceramic-brackets-with-different-base-designs-comparative-in-vitro-study
#16
Mohd Younus Ansari, Deepak K Agarwal, Ankur Gupta, Preeti Bhattacharya, Juhi Ansar, Ravi Bhandari
INTRODUCTION: Knowledge about the Shear Bond Strength (SBS) of ceramic brackets with different base design is essential as it affects bond strength to enamel. AIM: The aim of the present study was to evaluate and compare the effect of base designs of different ceramic brackets on SBS, and to determine the fracture site after debonding. MATERIALS AND METHODS: Four groups of ceramic brackets and one group of metal brackets with different base designs were used...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28046918/we-fg-202-01-early-prediction-of-radiotherapy-induced-skin-reactions-using-dynamic-infrared-imaging
#17
N Biswal, G Cifter, J Sun, N Sen, D Wang, A Diaz, K Griem, J Chu
PURPOSE: To predict radiotherapy induced skin reactions using dynamic infrared imaging. METHODS: Thermal images were captured by our homebuilt system consisting of two flash lamps and an infrared (IR) camera. The surface temperature of the skin was first raised by ∼ 6 oC from ∼1 ms flashes. The camera then captured a series of IR images for 10 seconds. For each image, a baseline skin temperature was recorded for 0.5sec before heat impulse. The temporal temperature gradients were calculated between a reference point (immediately after the flash) and at a time point 9sec after that...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28041599/influence-of-equol-and-resveratrol-supplementation-on-health-related-quality-of-life-in-menopausal-women-a-randomized-placebo-controlled-study
#18
RANDOMIZED CONTROLLED TRIAL
Sergio Davinelli, Giovanni Scapagnini, Fulvio Marzatico, Vincenzo Nobile, Nicola Ferrara, Graziamaria Corbi
OBJECTIVE: This study was designed to evaluate the effects of equol and resveratrol supplementation on health-related quality of life (HRQoL) in otherwise healthy menopausal women with hot flashes, anxiety and depressive symptoms. METHODS: Sixty recently menopausal women aged 50-55 years were randomized in a 12-week, placebo-controlled trial to receive 200mg of fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day). The primary outcome was the change in score on the Menopause Rating Scale (MRS), used to evaluate the severity of age-/menopause-related complaints...
February 2017: Maturitas
https://www.readbyqxmd.com/read/27993906/effect-of-investigation-intensity-and-treatment-differences-on-prostate-cancer-survivor-s-physical-symptoms-psychological-well-being-and-health-related-quality-of-life-a-two-country-cross-sectional-study
#19
Anna T Gavin, David Donnelly, Conan Donnelly, Frances J Drummond, Eileen Morgan, Gerard J Gormley, Linda Sharp
AIM: To investigate effects on men's health and well-being of higher prostate cancer (PCa) investigation and treatment levels in similar populations. PARTICIPANTS: PCa survivors in Ireland where the Republic of Ireland (RoI) has a 50% higher PCa incidence than Northern Ireland (NI). METHOD: A cross-sectional postal questionnaire was sent to PCa survivors 2-18 years post-treatment, seeking information about current physical effects of treatment, health-related quality of life (HRQoL; EORTC QLQ-C30; EQ-5D-5L) and psychological well-being (21 question version of the Depression, Anxiety and Stress Scale, DASS-21)...
December 19, 2016: BMJ Open
https://www.readbyqxmd.com/read/27977466/extremely-small-pseudoparamagnetic-iron-oxide-nanoparticle-as-a-novel-blood-pool-t1-magnetic-resonance-contrast-agent-for-3-t-whole-heart-coronary-angiography-in-canines-comparison-with-gadoterate-meglumine
#20
Eun-Ah Park, Whal Lee, Young Ho So, Yun-Sang Lee, Bong-Sik Jeon, Kyu Sung Choi, Eung-Gyu Kim, Wan-Jae Myeong
OBJECTIVE: The aim of this study was to evaluate an extremely small pseudoparamagnetic iron oxide nanoparticle (ESPIO), KEG3, as a potential blood pool agent in 3 T coronary magnetic resonance angiography (MRA) in canine models and compare its efficacy to that of a gadolinium-based contrast agent. MATERIALS AND METHODS: Nine mongrel dogs were subjected to whole-heart coronary MRA in 2 separate sessions at 7-day intervals with a 3 T scanner using the FLASH sequence with either gadoterate meglumine (Gd-DOTA) or the ESPIO (KEG3)...
February 2017: Investigative Radiology
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