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https://www.readbyqxmd.com/read/29334798/vulvar-vestibular-effects-of-ospemifene-a-pilot-study
#1
Filippo Murina, Stefania Di Francesco, Silvia Oneda
The study aimed to assess the effects of ospemifene on vulvar vestibule in postmenopausal women with vulvar pain and dyspareunia. Fifty-five postmenopausal women used oral ospemifene 60 mg/d for 60 d. Symptoms of dryness, burning, and dyspareunia were evaluated on a 10 cm visual analog scale. Visual examination of the vulvar vestibule was also conducted. Patients also underwent current perception threshold (CPT) testing obtained from the vulvar vestibule. Fifty-five patients (94.6%) completed the treatment...
January 15, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29332222/efficacy-of-crocus-sativus-saffron-in-treatment-of-major-depressive-disorder-associated-with-post-menopausal-hot-flashes-a-double-blind-randomized-placebo-controlled-trial
#2
Ladan Kashani, Sophia Esalatmanesh, Farzaneh Eftekhari, Samrand Salimi, Tahereh Foroughifar, Farnaz Etesam, Hamideh Safiaghdam, Ehsan Moazen-Zadeh, Shahin Akhondzadeh
PURPOSE: Due to concerns regarding the side effects of hormone therapy, many studies have focused on the development of non-hormonal agents for treatment of hot flashes. The aim of this study was to evaluate the efficacy and safety of saffron (stigma of Crocus sativus) in treatment of major depressive disorder associated with post-menopausal hot flashes. METHODS: Sixty women with post-menopausal hot flashes participated in this study. The patients randomly received either saffron (30 mg/day, 15 mg twice per day) or placebo for 6 weeks...
January 13, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29290208/quality-of-life-among-postmenopausal-women-enrolled-in-the-minnesota-green-tea-trial
#3
Allison Dostal Webster, Deborah A Finstad, Mindy S Kurzer, Carolyn J Torkelson
BACKGROUND: Postmenopausal symptomatology has not been elucidated in large, long-term human clinical trials. Our objective was to measure quality of life in postmenopausal women aged 50-70 years. METHODS: A Menopause-Specific Quality of Life-Intervention (MENQOL) questionnaire was completed by women enrolled in the Minnesota Green Tea Trial (n=932) to assess vasomotor, physical, sexual, and psychosocial symptoms in the years following menopause. Responses were coded; mean overall and domain scores ranged from 1 to 8...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29273859/the-effect-of-novel-glucose-monitoring-system-flash-glucose-monitoring-on-mental-well-being-and-treatment-satisfaction-in-japanese-people-with-diabetes
#4
Sumie Mitsuishi, Rimei Nishimura, Shin-Ichi Harashima, Tomoyuki Kawamura, Daisuke Tsujino, Keiko Koide, Akiko Nishimura, Kazunori Utsunomiya, Nobuya Inagaki, Yoshihito Atsumi
INTRODUCTION: FreeStyle Libre (Abbot Diabetes Care Ltd) has been launched as a novel glucose monitoring system called flash glucose monitoring (FGM) in Europe. Several reports are becoming available on its usefulness and safety. To date, however, reports from Asian countries have not been made available. In this study, we evaluated its usefulness in Japanese people with diabetes in terms of its mental well-being and patient satisfaction outcomes. METHODS: Individuals with type 1 and 2 diabetes treated with insulin were enrolled, and they performed self-monitoring of blood glucose...
December 22, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29239633/spatial-but-not-temporal-numerosity-thresholds-correlate-with-formal-math-skills-in-children
#5
Giovanni Anobile, Roberto Arrighi, Elisa Castaldi, Eleonora Grassi, Lara Pedonese, Paula A M Moscoso, David C Burr
Humans and other animals are able to make rough estimations of quantities using what has been termed the approximate number system (ANS). Much evidence suggests that sensitivity to numerosity correlates with symbolic math capacity, leading to the suggestion that the ANS may serve as a start-up tool to develop symbolic math. Many experiments have demonstrated that numerosity perception transcends the sensory modality of stimuli and their presentation format (sequential or simultaneous), but it remains an open question whether the relationship between numerosity and math generalizes over stimulus format and modality...
December 14, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/29231429/-comparison-between-manual-acupuncture-and-electroacupuncture-for-hot-flashes-and-sex-hormone-of-perimenopausal-syndrome
#6
Zhiliang Cao, Jian Tang, Yuting Xue, Qiong Wang, Saiqun Li, Youjun Zhou, Wei Zhang
OBJECTIVE: To compare the effect and differences sex the influence of hormone levels of perimenopau-sal syndrome patients between manual acupuncture and electroacupuncture (EA). METHODS: A total of 50 cases with perimenopausal syndrome were randomly assigned into an manual acupuncture group (27 cases) and an EA group (23 cases), and 1 case dropped in the EA group. The acupoints in the two groups were Guanyuan (CV 4), Zigong (EX-CA 1), Tianshu (ST 25), and Sanyinjiao (SP 6)...
March 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230878/a-randomized-controlled-pilot-study-of-continuous-glucose-monitoring-and-flash-glucose-monitoring-in-people-with-type-1-diabetes-and-impaired-awareness-of-hypoglycaemia
#7
M Reddy, N Jugnee, A El Laboudi, E Spanudakis, S Anantharaja, N Oliver
AIM: Hypoglycaemia in Type 1 diabetes is associated with mortality and morbidity, especially where awareness of hypoglycaemia is impaired. Clinical pathways for access to continuous glucose monitoring (CGM) and flash glucose monitoring technologies are unclear. We assessed the impact of CGM and flash glucose monitoring in a high-risk group of people with Type 1 diabetes. METHODS: A randomized, non-masked parallel group study was undertaken. Adults with Type 1 diabetes using a multiple-dose insulin-injection regimen with a Gold score of ≥ 4 or recent severe hypoglycaemia were recruited...
December 12, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29225446/use-of-internet-for-general-and-dental-health-along-acculturation-features-in-a-sample-of-mexican-americans
#8
Odette Aguirre, Rodrigo Mariño, Carlo Medina-Solís, Gerardo Maupomé
The objectives of this study were to explore self-reported Internet and electronic platforms used to search for and store medical and dental information among people of Mexican origin. A sample of adults self-identified as European American (250) and as Mexican American (255), residing in Central Indiana, answered a one-time survey that included technology use questions and measured acculturation via the Psychological-Behavioral Acculturation Scale. Overall use of information technologies was estimated through an Information and Communication Technology score...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/29209244/processing-of-a-subliminal-rebus-during-sleep-idiosyncratic-primary-versus-secondary-process-associations-upon-awakening-from-rem-versus-non-rem-sleep
#9
Jana Steinig, Ariane Bazan, Svenja Happe, Sarah Antonetti, Howard Shevrin
Primary and secondary processes are the foundational axes of the Freudian mental apparatus: one horizontally as a tendency to associate, the primary process, and one vertically as the ability for perspective taking, the secondary process. Primary process mentation is not only supposed to be dominant in the unconscious but also, for example, in dreams. The present study tests the hypothesis that the mental activity during REM-sleep has more characteristics of the primary process, while during non-REM-sleep more secondary process operations take place...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29207728/the-effect-of-soy-isoflavones-on-the-menopause-rating-scale-scoring-in-perimenopausal-and-postmenopausal-women-a-pilot-study
#10
Marya Ahsan, Ayaz Khurram Mallick
Introduction: Menopause is associated with many unpleasant symptoms which vary in different phases of menopausal transition. Although, Hormone Replacement Therapy (HRT) is considered the most effective mode of treatment for these symptoms, its use is associated with increased risk of breast cancer, endometrial cancer and thromboembolic events. Soy isoflavones are being widely used as a safer alternative to HRT, even though scientific evidence of their efficacy is poor or lacking. Aim: To study the effect of soy isoflavone supplementation on the menopausal symptoms in perimenopausal and postmenopausal women...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29200839/prediction-of-risk-of-depressive-symptoms-in-menopausal-women-based-on-hot-flash-and-sweating-symptoms-a-multicentre-study
#11
Yanwei Zheng, Yibei Zhou, Jiangshan Hu, Jieping Zhu, Qi Hua, Minfang Tao
Objective: The present study aimed to develop a symptom-based (namely, hot flashes and sweating) scoring system for predicting the risk of depressive symptoms in menopausal women via a multicentre cross-sectional survey. Methods: The data examined in the present study were obtained from 1,004 women aged 40-60 years who underwent physical examination at A Hospital. The basic information was obtained using a questionnaire-based survey. A self-rating depression scale was used to obtain the depressive symptom scores, while the Kupperman Menopausal Index was used to obtain the scores for the frequency of hot flashes and sweating...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29190404/sex-ed-by-brown-med-a-student-run-curriculum-and-its-impact-on-sexual-health-knowledge
#12
Erica Duh, Sheyla P Medina, Nathan Coppersmith, Naomi Adjei, Mary B Roberts, Susanna Magee
BACKGROUND AND OBJECTIVES: Risky sexual behavior among adolescents is a public health crisis. We describe a novel approach to sexual health education where medical students manage a curriculum for an entire seventh grade in one Rhode Island city to better equip students with comprehensive knowledge about sexual health. METHODS: Medical students were trained to teach 12 sessions to seventh-grade students under the supervision of the classroom teacher using a curriculum designed by medical students and faculty (modeled on the Family Life and Sexual Health [FLASH] curriculum but tailored to meet the community's needs)...
November 2017: Family Medicine
https://www.readbyqxmd.com/read/29146256/isolation-purification-structural-elucidation-and-antimicrobial-activities-of-kocumarin-a-novel-antibiotic-isolated-from-actinobacterium-kocuria-marina-cmg-s2-associated-with-the-brown-seaweed-pelvetia-canaliculata
#13
Bushra Uzair, Farid Menaa, Barkat Ali Khan, Faryal Vali Mohammad, Viqar Uddin Ahmad, Ryad Djeribi, Bouzid Menaa
AIMS: Screening of seaweed-associated bacteria capable of producing antimicrobials. METHODS AND RESULTS: Fifteen microbial strains, associated to the brown seaweed Pelvetia canaliculata (Linnaeus) attached to the rocks of Sonmiani Beach (Karachi, Pakistan), were screened. Crude extract filtrates of CMG S2 strain grew on Zobell marine agar (ZMA) had the most remarkable antimicrobial activity. Based on its phenotypic aspects (e.g. Gram-positive, microccoid form), biochemical characteristics (e...
January 2018: Microbiological Research
https://www.readbyqxmd.com/read/29077767/expectancy-after-the-first-treatment-and-response-to-acupuncture-for-menopausal-hot-flashes
#14
Carolyn C Ee, Sharmala Thuraisingam, Marie V Pirotta, Simon D French, Charlie C Xue, Helena J Teede
BACKGROUND: Evidence on the impact of expectancy on acupuncture treatment response is conflicting. OBJECTIVES: This secondary analysis of a randomized sham-controlled trial on acupuncture for menopausal hot flashes investigated whether treatment expectancy score was associated with hot flash score at end-of-treatment. Secondary analyses investigated whether there were associations between other pre-specified factors and hot flash score. STUDY DESIGN: Women experiencing moderately-severe hot flashes were randomized to receive 10 sessions of real or sham acupuncture over eight weeks...
2017: PloS One
https://www.readbyqxmd.com/read/29069110/vortioxetine-for-major-depressive-disorder-vasomotor-and-cognitive-symptoms-associated-with-the-menopausal-transition
#15
Marlene P Freeman, Laura J Cheng, Danna Moustafa, Abigail Davies, Alexandra Z Sosinsky, Betty Wang, Laura F Petrillo, Charlotte Hogan, Lee S Cohen
BACKGROUND: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. METHODS: Perimenopausal and early postmenopausal women with MDD (N = 27) received 8 weeks of open-label, flexible-dose treatment with vortioxetine. The Montgomery-Åsberg Depression Rating Scale (MADRS) was the primary outcome measure. Secondary measures included: HF frequency, the Greene Climacteric Scale (GCS), Menopause-Specific Quality of Life Questionnaire (MEN-QOL), Beck Anxiety Inventory (BAI), Cognitive and Physical Functioning Questionnaire (CPFQ), Digit Symbol Substitution Test (DSST), and Cogstate testing...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29067142/intermittent-96-hour-auricular-electroacupuncture-for-hot-flashes-in-patients-with-prostate-cancer-a-pilot-study
#16
Tyvin Rich, Gerald W Porter, Luisel Ricks-Santi, Tzvi Milshtein, Thomas Corbin
Objective: The hot flash is a common vasomotor disorder that causes distress in menopausal women and that can be debilitating in men with prostate cancer who are treated with androgen deprivation therapy (ADT). The utility of auricular electroacupuncture (AEA) was tested exclusively for a small cohort of men with ADT-induced vasomotor symptoms while the men underwent a course of curative radiotherapy. Materials and Methods: Prior to and during radiotherapy treatment, men with vasomotor symptoms were given repeated questionnaires regarding severity and frequency of hot flashes, quality of life (QoL), and sleep over a 6-week span of an AEA protocol...
October 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/29063390/comparison-of-quality-of-life-between-2-year-and-3-or-more-year-administration-of-leuprorelin-acetate-every-3-months-depot-in-combination-with-tamoxifen-as-adjuvant-endocrine-treatment-in-premenopausal-patients-with-endocrine-responsive-breast-cancer-a-randomized
#17
Yasuo Ohashi, Eiichi Shiba, Hiroko Yamashita, Junichi Kurebayashi, Shinzaburo Noguchi, Hirotaka Iwase, Michihiro Yoshida, Tsukasa Fujimoto
BACKGROUND: We conducted an open-label, randomized controlled trial evaluating the appropriate treatment duration of leuprorelin acetate 3-month depot, TAP-144-SR (3M), administered postsurgically every 3 months for 2 years versus 3 or more (up to 5) years, in combination with tamoxifen, for 5 years in premenopausal endocrine-responsive breast cancer patients and reported similar survival benefit in the two treatment groups. We hereby present patient-reported quality of life (QOL) data obtained from this trial...
October 24, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29060868/real-time-analysis-on-ensemble-svm-scores-to-reduce-p300-speller-intensification-time
#18
Kha Vo, Diep N Nguyen, Ha Hoang Kha, Eryk Dutkiewicz
In most Brain-Computer Interface systems, especially the P300-Speller, there must be a harmonized balance between the accuracy and the spelling time. One major drawback of the classical 36-choice P300-Speller is the slow rate of character elicitation. This paper aims to propose a real-time signal processing method to decrease the spelling time by exploiting the score margins of the ensemble Support Vector Machine classifiers during real-time P300-Speller flashes, rather than just getting the classifiers' highest scores...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29024794/brain-computer-interface-with-the-p300-speller-usability-for-disabled-people-with-amyotrophic-lateral-sclerosis
#19
Violaine Guy, Marie-Hélène Soriani, Mariane Bruno, Théodore Papadopoulo, Claude Desnuelle, Maureen Clerc
OBJECTIVES: Amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease, restricts patients' communication capacity a few years after onset. A proof-of-concept of brain-computer interface (BCI) has shown promise in ALS and "locked-in" patients, mostly in pre-clinical studies or with only a few patients, but performance was estimated not high enough to support adoption by people with physical limitation of speech. Here, we evaluated a visual BCI device in a clinical study to determine whether disabled people with multiple deficiencies related to ALS would be able to use BCI to communicate in a daily environment...
October 10, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28834966/checklist-and-scoring-system-for-the-assessment-of-soft%C3%A2-tissue-preservation-in-ct-examinations-of-human-mummies-application-to-the-tyrolean-iceman
#20
Stephanie Panzer, Patrizia Pernter, Dario Piombino-Mascali, Rimantas Jankauskas, Stephanie Zesch, Wilfried Rosendahl, Gerhard Hotz, Albert R Zink
Purpose Soft tissues make a skeleton into a mummy and they allow for a diagnosis beyond osteology. Following the approach of structured reporting in clinical radiology, a recently developed checklist was used to evaluate the soft tissue preservation status of the Tyrolean Iceman using computed tomography (CT). The purpose of this study was to apply the "Checklist and Scoring System for the Assessment of Soft Tissue Preservation in CT Examinations of Human Mummies" to the Tyrolean Iceman, and to compare the Iceman's soft tissue preservation score to the scores calculated for other mummies...
December 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
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