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William D Erwin, Aaron C Jessop, Martha V Mar, Homer A Macapinlac, Osama R Mawlawi
OBJECTIVE: The aim of this study was to assess the feasibility of IQ-SPECT gated blood pool (MUGA) under conditions of decreased scan time (ST). PATIENTS AND METHODS: Ten patients underwent routine 26-min, two-view planar, followed by LEHR and IQ-SPECT MUGA, on a Siemens dual-head Symbia scanner. Six 'back and forth' 4-min SPECT scans were summed into 4-, 8-, 12-, 16-, 20-, and 24-min equivalent scans, and reconstructed iteratively (IQ-SPECT and LEHR) and with FBP (LEHR)...
October 21, 2016: Nuclear Medicine Communications
Fang Meng, Pei-Bei Duan, Junya Zhu, Qing-Qing Lou, Zhao-Hui Fang, Hong-Li An, Lan-Ying Liu, Yue Hu, Qian Hu
OBJECTIVE: This study aims to evaluate the effectiveness and safety of Gua sha therapy on perimenopausal symptoms, quality of life, and serum female hormones in participants with perimenopausal syndrome. METHODS: A prospective, randomized, controlled clinical trial was conducted at the First Affiliated Hospital of Nanjing University of Chinese Medicine in China. Eighty women with perimenopausal syndrome were recruited and randomized into an intervention group or a control group...
October 10, 2016: Menopause: the Journal of the North American Menopause Society
Savita Rani Singhal, Wansalan Kuru Shullai
OBJECTIVE: This study was planned to compare the effects of gabapentin and isoflavones in menopausal vasomotor symptoms. MATERIALS AND METHODS: This prospective comparative study was conducted on 100 patients with complaints of hot flashes, divided into two groups of 50 each. Group I received 900 mg of gabapentin and Group II received 60 mg of isoflavones daily for 3 months. The patients were interviewed to calculate hot flash, global and depression scores and were rescored after 2, 4, 8, and 12 weeks...
July 2016: Journal of Mid-life Health
Sarah J Bayless, Alistair J Harvey
The effect of alcohol intoxication on central and peripheral attention was examined as a test of Alcohol Myopia Theory (AMT). Previous research has supported AMT in the context of visual attention, but few studies have examined the effects of alcohol intoxication on central and peripheral attention. The study followed a 2 (alcohol treatment) × 2 (array size) × 2 (task type) mixed design. Forty-one participants (placebo or intoxicated) viewed an array of four or six colored circles, while simultaneously counting the flashes of a centrally presented fixation cross...
October 3, 2016: Perception
David F Archer, Ellen W Freeman, Barry S Komm, Kelly A Ryan, Ching-Ray Yu, Sebastian Mirkin, JoAnn V Pinkerton
OBJECTIVES: Conjugated estrogens/bazedoxifene (CE/BZA) reduced menopause-related hot flashes (HFs) in the Selective estrogens, Menopause, And Response to Therapy (SMART) trials. This post hoc pooled analysis of SMART-1 and -2 further characterized effects of CE/BZA on HFs in the overall population and patient subgroups. METHODS: Data from two randomized, double-blind, placebo- and active-controlled, phase 3 studies were pooled for nonhysterectomized postmenopausal women with moderate/severe HFs given CE 0...
September 27, 2016: Journal of Women's Health
Stefanie I Siebler, Ursula Gresser, Barbara M Richartz
Objective. This study aims to evaluate the effect of daily dietary nutritional supplement on somatic, psychological, and urogenital symptoms in postmenopausal women. Material and Methods. In this study 28 healthy, symptomatic, peri- and postmenopausal women of 47-67 years of age were allocated to use the nutritional supplement JuicePLUS+®. Primary research parameters: Menopause Rating Scale (MRS) was used to assess menopausal symptoms at baseline and after 8 and 16 weeks of treatment. Secondary parameters: proliferation behaviour of vaginal smear was scored at baseline and after treatment...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
Yusaku Takamura, Maho Imanishi, Madoka Osaka, Satoko Ohmatsu, Takanori Tominaga, Kentaro Yamanaka, Shu Morioka, Noritaka Kawashima
Unilateral spatial neglect is a common neurological syndrome following predominantly right hemispheric stroke. While most patients lack insight into their neglect behaviour and do not initiate compensatory behaviours in the early recovery phase, some patients recognize it and start to pay attention towards the neglected space. We aimed to characterize visual attention capacity in patients with unilateral spatial neglect with specific focus on cortical processes underlying compensatory gaze shift towards the neglected space during the recovery process...
September 23, 2016: Brain: a Journal of Neurology
R Bove, T Vaughan, T Chitnis, P Wicks, P L De Jager
BACKGROUND: Many women with multiple sclerosis (MS) are postmenopausal. Previously reported findings from an online MS cohort suggested that earlier, surgical menopause may be associated with higher patient-reported MS severity scores. OBJECTIVE: To explore experiences of menopause in a series of MS women responding to a reproductive survey from an online research platform, PatientsLikeMe (PLM). METHODS: The free-text responses from a detailed reproductive history survey deployed to PLM members were analyzed using grounded theory approach...
September 2016: Multiple Sclerosis and related Disorders
Julie L Otte, Jingwei Wu, Menggang Yu, Claire Shaw, Janet S Carpenter
BACKGROUND AND PURPOSE: Sleep hygiene is one factor that contributes to poor sleep in breast cancer survivors but is poorly measured. The purposes of this study were to (a) evaluate the psychometric properties of the Sleep Hygiene Awareness and Practice Scale (SHAPS) and (b) compare SHAPS scores between midlife women with and without breast cancer. METHODS: Cross-sectional, descriptive data from a single-blinded, controlled hot flash intervention trial. RESULTS: 194 women (88 breast cancer survivors; 106 menopausal women)...
2016: Journal of Nursing Measurement
J J Stirnemann, N Fries, R Bessis, M Fontanges, R Mangione, L J Salomon
OBJECTIVE: To assess potential differences in fetal size between the French population and the international population from the INTERGROWTH-21(st) (IG) project and to measure the impact of switching to the IG references for fetal size. DESIGN AND SETTING: Nationwide cross-sectional study of fetal ultrasound biometry. POPULATION: Low-risk pregnancies prospectively recruited within the network of the national French college of fetal ultrasound over a 6 week-period...
August 12, 2016: Ultrasound in Obstetrics & Gynecology
Ebru Gozuyesil, Muruvvet Baser
PURPOSE: This study aims to identify the effects of foot reflexology applied to women on their vasomotor complaints and quality of life. METHODS: A randomised controlled study was conducted with 120 women. The experimental group received foot reflexology treatment, while the control group received nonspecific foot massage. RESULTS: The mean scores for hot flashes, sweats, and night sweats, were lower in the reflexology group than the control group after the practice; and the difference between the groups was statistically significant (p < 0...
August 2016: Complementary Therapies in Clinical Practice
Alireza Salehi, Maryam Marzban, Abbas Rezian Zadeh
PURPOSE: The aim of this study was to evaluate the effectiveness of acupuncture for treatment of hot flash in women with breast cancer. METHODS: The aspects considered in this study included searching for 12 data bases until April 2015 and consulting reference lists of reviews and related articles. Additional features studied comprised all articles on human patients with breast cancer treated with needle acupuncture with or without electrical stimulation for the treatment of hot flashes...
August 6, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Ellen W Freeman, Mary D Sammel
OBJECTIVE: The aim of this study was to identify temporal associations of anxiety dimensions with menopausal hot flashes in women progressing through the menopausal transition. We hypothesized that associations of both somatic and affective dimensions of anxiety with hot flashes increased in the menopausal transition, and that somatic anxiety was an independent risk factor for menopausal hot flashes. METHODS: Hot flashes, anxiety symptoms, hormone levels, and other psychosocial variables were assessed annually for 14 years of follow-up...
September 2016: Menopause: the Journal of the North American Menopause Society
Shenghong He, Rui Zhang, Qihong Wang, Yang Chen, Tingyan Yang, Zhenghui Feng, Yuandong Zhang, Ming Shao, Yuanqing Li
The key issue of electroencephalography (EEG)- based brain switches is to detect the control and idle states in an asynchronous manner. Most existing methods rely on a threshold. However, it is often time consuming to select a satisfactory threshold, and the chosen threshold might be inappropriate over a long period of time due to the variability of the EEG signals. This paper presents a new P300-based threshold-free brain switch. Specifically, one target button and three pseudo buttons, which are intensified in a random order to produce P300 potential, are set in the graphical user interface...
July 13, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
C Bentow, G Lakos, P Martis, E Wahl, M Garcia, O Viñas, G Espinosa, R Cervera, C Sjöwall, D Carmona-Fernandes, M J Santos, J G Hanly, M Mahler
OBJECTIVE: Anti-double stranded desoxyribonucleic acid (anti-dsDNA) antibodies are considered fairly specific for systemic lupus erythematosus (SLE) and their quantification is useful for the clinical management of SLE patients. We assessed the diagnostic performance of the QUANTA Flash dsDNA chemiluminescent immunoassay (CIA) in comparison to an ELISA, using patients from five participating countries. The main focus was to evaluate the correlation between anti-dsDNA antibody results from the CIA and global SLE disease activity, as measured by the SLE Disease Activity Index 2000 (SLEDAI-2K)...
July 2016: Lupus
Juliano S Silveira, Ruth Clapauch, Maria das Graças C de Souza, Eliete Bouskela
OBJECTIVE: The aim of the study was to compare the endothelial function of symptomatic (self-reported hot flashes >3 on a scale of 0-10) versus asymptomatic (≤3) women in different postmenopause stages, and to examine if the association between hot flashes and endothelial function was independent of classical cardiovascular risk factors observed during the analysis. METHODS: Noninvasive venous occlusion plethysmography within two groups: recent (recent postmenopause [RPM], <10 y, n = 63) and late (late postmenopause [LPM], ≥10 y, n = 67) postmenopause...
August 2016: Menopause: the Journal of the North American Menopause Society
Susan M McCurry, Katherine A Guthrie, Charles M Morin, Nancy F Woods, Carol A Landis, Kristine E Ensrud, Joseph C Larson, Hadine Joffe, Lee S Cohen, Julie R Hunt, Katherine M Newton, Julie L Otte, Susan D Reed, Barbara Sternfeld, Lesley F Tinker, Andrea Z LaCroix
IMPORTANCE: Effective, practical, nonpharmacologic therapies are needed to treat menopause-related insomnia symptoms in primary and women's specialty care settings. OBJECTIVE: To evaluate the efficacy of telephone-based cognitive behavioral therapy for insomnia (CBT-I) vs menopause education control (MEC). DESIGN, SETTING, AND PARTICIPANTS: A single-site, randomized clinical trial was conducted from September 1, 2013, to August 31, 2015, in western Washington State among 106 perimenopausal or postmenopausal women aged 40 to 65 years with moderate insomnia symptoms (Insomnia Severity Index [ISI] score, ≥12) and 2 or more daily hot flashes...
July 1, 2016: JAMA Internal Medicine
Aaron D Besterman, Jody K Williams, Victor I Reus, Michele T Pato, Susan M Voglmaier, Carol A Mathews
OBJECTIVE: For psychiatry research resident career development, there is a recognized need for improved cross-institutional mentoring and networking opportunities. One method to address this need is via regional conferences, open to current and recently graduated research residents and their mentors. With this in mind, we developed the biennial California Psychiatry Research Resident Retreat (CPRRR) and collected feedback from participants to 1) Assess resident satisfaction, 2) Determine the utility of the retreat as a networking and mentorship tool, and 3) Identify areas for improvement...
May 13, 2016: Academic Psychiatry
Yan Zhao, Jorik Nonnekes, Erik J M Storcken, Sabine Janssen, Erwin E H van Wegen, Bastiaan R Bloem, Lucille D A Dorresteijn, Jeroen P P van Vugt, Tjitske Heida, Richard J A van Wezel
New mobile technologies like smartglasses can deliver external cues that may improve gait in people with Parkinson's disease in their natural environment. However, the potential of these devices must first be assessed in controlled experiments. Therefore, we evaluated rhythmic visual and auditory cueing in a laboratory setting with a custom-made application for the Google Glass. Twelve participants (mean age = 66.8; mean disease duration = 13.6 years) were tested at end of dose. We compared several key gait parameters (walking speed, cadence, stride length, and stride length variability) and freezing of gait for three types of external cues (metronome, flashing light, and optic flow) and a control condition (no-cue)...
June 2016: Journal of Neurology
Andreia C Freitas, Marzena Wylezinska, Malcolm J Birch, Steffen E Petersen, Marc E Miquel
Dynamic imaging of the vocal tract using real-time MRI has been an active and growing area of research, having demonstrated great potential to become routinely performed in the clinical evaluation of speech and swallowing disorders. Although many technical advances have been made in regards to acquisition and reconstruction methodologies, there is still no consensus in best practice protocols. This study aims to compare Cartesian and non-Cartesian real-time MRI sequences, regarding image quality and temporal resolution trade-off, for dynamic speech imaging...
2016: PloS One
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