keyword
MENU ▼
Read by QxMD icon Read
search

Responsive behavior

keyword
https://www.readbyqxmd.com/read/29793157/energy-dissipation-in-quasi-linear-viscoelastic-tissues-cells-and-extracellular-matrix
#1
Behzad Babaei, A J Velasquez-Mao, Kenneth M Pryse, William B McConnaughey, Elliot L Elson, Guy M Genin
Characterizing how a tissue's constituents give rise to its viscoelasticity is important for uncovering how hidden timescales underlie multiscale biomechanics. These constituents are viscoelastic in nature, and their mechanics must typically be assessed from the uniaxial behavior of a tissue. Confounding the challenge is that tissue viscoelasticity is typically associated with nonlinear elastic responses. Here, we experimentally assessed how fibroblasts and extracellular matrix (ECM) within engineered tissue constructs give rise to the nonlinear viscoelastic responses of a tissue...
May 21, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29793042/aminergic-neuromodulation-of-associative-visual-learning-in-harnessed-honey-bees
#2
Nino Mancini, Martin Giurfa, Jean-Christophe Sandoz, Aurore Avarguès-Weber
The honey bee Apis mellifera is a major insect model for studying visual cognition. Free-flying honey bees learn to associate different visual cues with a sucrose reward and may deploy sophisticated cognitive strategies to this end. Yet, the neural bases of these capacities cannot be studied in flying insects. Conversely, immobilized bees are accessible to neurobiological investigation but training them to respond appetitively to visual stimuli paired with sucrose reward is difficult. Here we succeeded in coupling visual conditioning in harnessed bees with pharmacological analyses on the role of octopamine (OA), dopamine (DA) and serotonin (5-HT) in visual learning...
May 21, 2018: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29793014/calf-muscle-oxygen-saturation-during-six-minute-walk-test-and-its-relationship-with-walking-impairment-in-symptomatic-peripheral-artery-disease
#3
Aluísio Andrade-Lima, Gabriel G Cucato, Wagner J R Domingues, Antônio H Germano-Soares, Bruno R Cavalcante, Marilia A Correia, Glauco F Saes, Nelson Wolosker, Andrew W Gardner, Antônio E Zerati, Raphael M Ritti-Dias
OBJECTIVE: Impaired microcirculation is associated with poor walking capacity in symptomatic peripheral artery disease (PAD) patients during treadmill test, however, this test does not simulate the efforts of daily walking of these patients. Thus, the aim of the study was to describe the microcirculation responses during six-minute walk test (6MWT) and to analyze the relationship between microcirculation indicators and walking impairment in symptomatic PAD patients. METHODS: Thirty-four patients were included (mean age = 67...
May 21, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29792867/effects-of-amphetamine-exposure-during-adolescence-on-behavior-and-prelimbic-cortex-neuron-activity-in-adulthood
#4
Luke K Sherrill, Joshua M Gulley
Repeated exposure to psychostimulants during adolescence produces long-lasting changes in behavior that may be mediated by disrupted development of the mesocorticolimbic dopamine system. Here, we tested this hypothesis by assessing the effects of amphetamine (AMPH) and dopamine receptor-selective drugs on behavior and neuron activity in the prelimbic region of the medial prefrontal cortex (PFC). Adolescent male, Sprague-Dawley rats were given saline or 3 mg/kg AMPH between postnatal day (P) 27 and P45. In Experiment 1, locomotor behavior was assessed during adulthood following challenges with a dopamine D1 (SKF 82958) or D2 (quinpirole) receptor-selective agonist...
May 21, 2018: Brain Research
https://www.readbyqxmd.com/read/29792582/advancing-child-sexual-abuse-prevention-in-schools-an-exploration-of-the-effectiveness-of-the-enough-online-training-program-for-k-12-teachers
#5
Melinda Gushwa, Jetta Bernier, David Robinson
Child sexual abuse (CSA) in schools and educator misconduct represents a threat to the safety and well-being of our children. The Enough! Preventing Child Sexual Abuse in My School program is a 1-hour online training course developed to address the problem of sexual misconduct and CSA in K-12 education via the use of two avatars/teachers who are navigating CSA and misconduct in their schools. One hundred and thirty-four teachers from three school districts participated in a study to examine the effectiveness of the program in terms of knowledge awareness, including prevalence rates, types of CSA behaviors, impact of CSA on children, signs and symptoms, reporting responsibilities and responses to suspected abuse...
May 24, 2018: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29792504/measurement-invariance-of-tgmd-3-in-children-with-and-without-mental-and-behavioral-disorders
#6
Daniele Magistro, Giovanni Piumatti, Fabio Carlevaro, Lauren B Sherar, Dale W Esliger, Giulia Bardaglio, Francesca Magno, Massimiliano Zecca, Giovanni Musella
This study evaluated whether the Test of Gross Motor Development 3 (TGMD-3) is a reliable tool to compare children with and without mental and behavioral disorders across gross motor skill domains. A total of 1,075 children (aged 3-11 years), 98 with mental and behavioral disorders and 977 without (typically developing), were included in the analyses. The TGMD-3 evaluates fundamental gross motor skills of children across two domains: locomotor skills and ball skills. Two independent testers simultaneously observed children's performances (agreement over 95%)...
May 24, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29792497/examining-the-stability-of-social-emotional-and-behavioral-risk-status-implications-for-screening-frequency
#7
Faith G Miller, Sandra M Chafouleas, Megan E Welsh, T Chris Riley-Tillman, Gregory A Fabiano
Responsive service delivery frameworks rely on the use of screening approaches to identify students in need of support and to guide subsequent assessment and intervention efforts. However, limited empirical investigations have been directed to informing how often screening should occur for social, emotional, and behavioral difficulties in school settings. The purpose of the current study was to evaluate the stability of risk status on 3 different screening instruments across 3 administrations across the course of a school year...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792443/sympathy-and-responses-to-suffering-similarity-and-variation-in-china-and-the-united-states
#8
Jennifer L Goetz, Kaiping Peng
Feeling sympathy in response to suffering appears to be a universal human experience, but we know very little about how it is experienced in non-Western cultures. In the present studies, we show that sympathy is a complex emotion that has a distinct appraisal theme of wanting to alleviate suffering and that cultural variation occurs in interpretations of suffering and behavioral responses. In particular, the present studies show that sympathy is conceptualized similarly in both the United States and China (Studies 1 and 2), and that it is elicited by undeserved suffering in both cultures (Study 2), is experienced as unpleasant (Study 2), and motivates a desire to help others (Studies 2, 3, and 4)...
May 24, 2018: Emotion
https://www.readbyqxmd.com/read/29792131/management-of-nursing-workplace-incivility-in-the-health-care-settings-a-systematic-review
#9
Nancy Armstrong
Workplace incivility is a well-documented issue in nursing in the health care setting. It has the potential to cause emotional and physical distress in victims and potentially affects the quality of care provided. The purpose of this study was to critique and summarize the most recent, available evidence related to interventions in assisting nursing staff working in health care settings in managing incivility. This systematic review of literature yielded 10 studies meeting the criteria. The studies were mostly identified as lower quality research...
May 1, 2018: Workplace Health & Safety
https://www.readbyqxmd.com/read/29792030/on-the-role-of-counterions-in-molecularly-imprinted-polymers-for-anionic-species
#10
Sabine Wagner, Carlos Zapata, Wei Wan, Kornelia Gawlitza, Marcus Weber, Knut Rurack
Small-molecule oxoanions are often imprinted noncovalently as carboxylates into molecularly imprinted polymers (MIPs), requiring the use of an organic counterion. Popular species are either pentamethylpiperidine (PMP) as a protonatable cation or tetraalkylammonium (TXA) ions as permanent cations. The present work explores the influence of the TXA as a function of their alkyl chain length, from methyl to octyl, using UV/vis absorption, fluorescence titrations and HPLC, as well as MD simulations. Protected phenylalanines (Z-L/D-Phe) served as templates/analytes...
May 23, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29791872/gene-expression-in-cord-blood-links-genetic-risk-for-neurodevelopmental-disorders-with-maternal-psychological-distress-and-adverse-childhood-outcomes
#11
Michael S Breen, Aliza P Wingo, Nastassja Koen, Kirsten A Donald, Mark Nicol, Heather J Zar, Kerry J Ressler, Joseph D Buxbaum, Dan J Stein
Prenatal exposure to maternal stress and depression has been identified as a risk factor for adverse behavioral and neurodevelopmental outcomes in early childhood. However, the molecular mechanisms through which maternal psychopathology shapes offspring development remain poorly understood. We applied transcriptome-wide screens to 149 umbilical cord blood samples from neonates born to mothers with posttraumatic stress disorder (PTSD; n=20), depression (n=31) and PTSD with comorbid depression (n=13), compared to carefully matched trauma exposed controls (n=23) and healthy mothers (n=62)...
May 20, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29791868/ontogeny-of-white-matter-toll-like-receptor-expression-and-motor-skills-in-the-neonatal-ferret
#12
Jessica M Snyder, Thomas R Wood, Kylie Corry, Daniel H Moralejo, Pratik Parikh, Sandra E Juul
Inflammation caused by perinatal infection, superimposed with hypoxia and/or hyperoxia, appears to be important in the pathogenesis of preterm neonatal encephalopathy, with white matter particularly vulnerable during the third trimester. The associated inflammatory response is at least partly mediated through Toll-like receptor (TLR)-dependent mechanisms. Immunohistochemistry, gene expression, and behavioral studies were used to characterize white matter development and determine TLR3 and TLR4 expression and accumulation in the neonatal ferret brain...
May 20, 2018: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29791860/the-olfactory-logic-behind-fruit-odor-preferences-in-larval-and-adult-drosophila
#13
Hany K M Dweck, Shimaa A M Ebrahim, Tom Retzke, Veit Grabe, Jerrit Weißflog, Ales Svatoš, Bill S Hansson, Markus Knaden
Despite the comprehensive knowledge on odor coding, our understanding of the relationship between sensory input and behavioral output in Drosophila remains weak. Here, we measure the behavioral responses generated by larval and adult flies in response to 34 fruit odors and find that larval preference for fruit odors differs from that of adult flies. Next, we provide a functional analysis of the full repertoire of the peripheral olfactory system using the same comprehensive stimulus spectrum. We find that 90% and 53% of larval and adult olfactory receptors tested here, respectively, are involved in evaluating these fruit odors...
May 22, 2018: Cell Reports
https://www.readbyqxmd.com/read/29791803/bacteria-activated-janus-particles-driven-by-chemotaxis
#14
Zihan Huang, Pengyu Chen, Guo-Long Zhu, Ye Yang, Ziyang Xu, Li-Tang Yan
In the development of biocompatible nano/micro-motors for drug and cargo delivery, motile bacteria represent an excellent energy source for biomedical applications. Despite intense research of the fabrication of bacteria-based motors, how to effectively utilize the instinctive responses of bacteria to environmental stimuli in the fabrication process, particularly, chemotaxis, remains an urgent and critical issue. Here, by developing a molecular-dynamics model of bacterial chemotaxis, we present an investigation of the transport of a bacteria-activated Janus particle driven by chemotaxis...
May 23, 2018: ACS Nano
https://www.readbyqxmd.com/read/29791746/molecular-and-cellular-characterization-of-nachr-subtypes-in-the-arcuate-nucleus-of-the-mouse-hypothalamus
#15
Cali A Calarco, Zhiying Li, Seth R Taylor, Somin Lee, Wenliang Zhou, Jeffrey M Friedman, Yann S Mineur, Cecilia Gotti, Marina R Picciotto
Nicotine, acting through nicotinic acetylcholine receptors (nAChRs), increases the firing rate of both orexigenic agouti-related peptide (AgRP) and anorexigenic pro-opiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC), yet nicotine and other nAChR agonists decrease food intake in mice. Viral-mediated knockdown of β4 nAChR subunit in all neuronal cell types in the ARC prevents the nicotinic agonist cytisine from decreasing food intake, but it is not known whether the β4 subunit is selectively expressed in anorexogenic neurons or how other nAChR subtypes are distributed in this nucleus...
May 23, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29791517/costs-of-cold-acclimation-on-survival-and-reproductive-behavior-in-drosophila-melanogaster
#16
Elizabeth R Everman, Jennifer L Delzeit, F Kate Hunter, Jennifer M Gleason, Theodore J Morgan
Fitness is determined by the ability of an organism to both survive and reproduce; however, the mechanisms that lead to increased survival may not have the same effect on reproductive success. We used nineteen natural Drosophila melanogaster genotypes from the Drosophila Genetic Reference Panel to determine if adaptive plasticity following short-term acclimation through rapid cold-hardening (RCH) affects mating behavior and mating success. We confirmed that exposure to the acclimation temperature is beneficial to survival following cold stress; however, we found that this same acclimation temperature exposure led to less efficient male courtship and a significant decrease in the likelihood of mating...
2018: PloS One
https://www.readbyqxmd.com/read/29790938/the-low-threshold-calcium-channel-cav3-2-mediates-burst-firing-of-mature-dentate-granule-cells
#17
Mael Dumenieu, Oleg Senkov, Andrey Mironov, Emmanuel Bourinet, Michael R Kreutz, Alexander Dityatev, Martin Heine, Arthur Bikbaev, Jeffrey Lopez-Rojas
Mature granule cells are poorly excitable neurons that were recently shown to fire action potentials, preferentially in bursts. It is believed that the particularly pronounced short-term facilitation of mossy fiber synapses makes granule cell bursting a very effective means of properly transferring information to CA3. However, the mechanism underlying the unique bursting behavior of mature granule cells is currently unknown. Here, we show that Cav3.2 T-type channels at the axon initial segment are responsible for burst firing of mature granule cells in rats and mice...
April 18, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29790868/altered-prefrontal-correlates-of-monetary-anticipation-and-outcome-in-chronic-pain
#18
Katherine T Martucci, Nicholas Borg, Kelly H MacNiven, Brian Knutson, Sean C Mackey
Chronic pain may alter both affect- and value-related behaviors, which represents a potentially treatable aspect of chronic pain experience. Current understanding of how chronic pain influences the function of brain reward systems, however, is limited. Using a monetary incentive delay task and functional magnetic resonance imaging (fMRI), we measured neural correlates of reward anticipation and outcomes in female participants with the chronic pain condition of fibromyalgia (N = 17) and age-matched, pain-free, female controls (N = 15)...
April 4, 2018: Pain
https://www.readbyqxmd.com/read/29790548/role-of-flower-like-ultrathin-co-3-o-4-nanosheets-in-water-splitting-and-non-aqueous-li-o-2-batteries
#19
Haitao Wu, Wang Sun, Junrong Shen, David W Rooney, Zhenhua Wang, Kening Sun
The oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are both fundamental and essential processes for various energy conversion and storage systems. The kinetics of ORR and OER play a critical role in their energy efficiency and practicality. Here, flower-like ultrathin Co3O4 nanosheets synthesized through a facile solvothermal technique were studied as a bifunctional catalyst for both water splitting and non-aqueous Li-O2 batteries. Due to the novel structure and highly active {110} and {100} exposed facets, which can effectively facilitate mass transfer and enhance catalytic capability, Co3O4 nanosheets exhibit better stability and higher ORR/OER activity than Co3O4 nanoparticles, Co3O4 bulks, Pt/C, and RuO2 in alkaline solution...
May 23, 2018: Nanoscale
https://www.readbyqxmd.com/read/29790419/rictor-gene-amplification-is-correlated-with-metastasis-and-therapeutic-resistance-in-triple-negative-breast-cancer
#20
Said El Shamieh, Fatima Saleh, Salim Moussa, Joseph Kattan, Fadi Farhat
Triple-negative breast cancer (TNBC) is characterized by its aggressive behavior, metastasis and lack of targeted therapies. Herein, we discuss the clinical, histopathological and genetic profile of a woman diagnosed with TNBC. Since the patient had no durable response to chemotherapy, a genetic profiling was carried out. Next-generation sequencing analysis of 592 genes showed a missense mutation, p.E545A in PIK3CA, thus the patient was started on the mTOR inhibitor everolimus, in combination with exemestane, which controlled her pain; however, the disease progressed aggressively...
May 23, 2018: Pharmacogenomics
keyword
keyword
120798
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"