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https://www.readbyqxmd.com/read/29352760/endothelial-function-estimated-by-digital-reactive-hyperemia-in-patients-with-atherosclerotic-risk-factors-or-coronary-artery-disease
#1
Jeehoon Kang, Hack-Lyoung Kim, Jae-Bin Seo, Jin-Yong Lee, Min-Kyong Moon, Woo-Young Chung
Due to the complex profile of atherosclerotic risk factors, an integrated analysis of a specific individual is difficult. Endothelial function reflects a composite of various risk factors, and may be used as an optimal tool to estimate the overall atherosclerotic risk. In this study, we investigated the value of digital Reactive Hyperemia Index (RHI) in an actual population with multiple atherosclerotic risk factors or coronary artery disease (CAD). A total of 417 patients from the Seoul National University Boramae Medical Center RHI registry were enrolled in this study...
January 19, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29352285/deep-neural-networks-show-an-equivalent-and-often-superior-performance-to-dermatologists-in-onychomycosis-diagnosis-automatic-construction-of-onychomycosis-datasets-by-region-based-convolutional-deep-neural-network
#2
Seung Seog Han, Gyeong Hun Park, Woohyung Lim, Myoung Shin Kim, Jung Im Na, Ilwoo Park, Sung Eun Chang
Although there have been reports of the successful diagnosis of skin disorders using deep learning, unrealistically large clinical image datasets are required for artificial intelligence (AI) training. We created datasets of standardized nail images using a region-based convolutional neural network (R-CNN) trained to distinguish the nail from the background. We used R-CNN to generate training datasets of 49,567 images, which we then used to fine-tune the ResNet-152 and VGG-19 models. The validation datasets comprised 100 and 194 images from Inje University (B1 and B2 datasets, respectively), 125 images from Hallym University (C dataset), and 939 images from Seoul National University (D dataset)...
2018: PloS One
https://www.readbyqxmd.com/read/29350137/multiplex-pcr-based-next-generation-sequencing-and-global-diversity-of-seoul-virus-in-humans-and-rats
#3
Won-Keun Kim, Jin Sun No, Seung-Ho Lee, Dong Hyun Song, Daesang Lee, Jeong-Ah Kim, Se Hun Gu, Sunhye Park, Seong Tae Jeong, Heung-Chul Kim, Terry A Klein, Michael R Wiley, Gustavo Palacios, Jin-Won Song
Seoul virus (SEOV) poses a worldwide public health threat. This virus, which is harbored by Rattus norvegicus and R. rattus rats, is the causative agent of hemorrhagic fever with renal syndrome (HFRS) in humans, which has been reported in Asia, Europe, the Americas, and Africa. Defining SEOV genome sequences plays a critical role in development of preventive and therapeutic strategies against the unique worldwide hantavirus. We applied multiplex PCR-based next-generation sequencing to obtain SEOV genome sequences from clinical and reservoir host specimens...
February 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29345633/impacts-of-an-exercise-program-and-motivational-telephone-counseling-on-health-related-quality-of-life-in-people-with-parkinson-s-disease
#4
JuHee Lee, MoonKi Choi, Yonju Yoo, Sangwoo Ahn, Justin Y Jeon, Ji Young Kim, Ji Yong Byun
PURPOSE: The purpose of this study was to test the effects of group exercise and telephone counseling on physical and psychosocial health in people with Parkinson's disease (PD). DESIGN: This was a quasiexperimental study with a nonequivalent control group. METHODS: This study took place in Seoul, South Korea. Twenty-two and 20 subjects participated in the intervention and comparison groups, respectively. The intervention group performed group exercises twice a week and received motivational telephone counseling every 2 weeks for 12 weeks...
November 14, 2017: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
https://www.readbyqxmd.com/read/29345022/seroprevalence-of-helicobacter-pylori-in-korea-a-multicenter-nationwide-study-conducted-in-2015-and-2016
#5
Jeong Hoon Lee, Kee Don Choi, Hwoon-Yong Jung, Gwang Ho Baik, Jong Kyu Park, Sung Soo Kim, Byung-Wook Kim, Su Jin Hong, Hyun Lim, Cheol Min Shin, Si Hyung Lee, Seong Woo Jeon, Ji Hyun Kim, Cheol Woong Choi, Hye-Kyung Jung, Jie-Hyun Kim, Suck Chei Choi, Jin Woong Cho, Wan Sik Lee, Soo-Young Na, Jae Kyu Sung, Kyung Ho Song, Jun-Won Chung, Sung-Cheol Yun
BACKGROUND: The Korean College of Helicobacter and Upper Gastrointestinal Research has studied Helicobacter pylori (H. pylori) prevalence since 1998 and found a dynamic change in its prevalence in Korea. The aim of this study was to determine the recent H. pylori prevalence rate and compare it with that of previous studies according to socioeconomic variables. METHODS: We planned to enroll 4920 asymptomatic Korean adults from 21 centers according to the population distribution of seven geographic areas (Seoul, Gyeonggi, Gangwon, Chungcheong, Kyungsang, Cholla, and Jeju)...
January 18, 2018: Helicobacter
https://www.readbyqxmd.com/read/29343812/high-albumin-level-is-a-predictor-of-favorable-response-to-immunotherapy-in-autoimmune-encephalitis
#6
Yoonhyuk Jang, Soon-Tae Lee, Tae-Joon Kim, Jin-Sun Jun, Jangsup Moon, Keun-Hwa Jung, Kyung-Il Park, Kon Chu, Sang Kun Lee
There is no known biomarker that predicts the response to immune therapy in autoimmune synaptic encephalitis. Thus, we investigated serum albumin as a prognostic biomarker of early immune therapies in patients with autoimmune encephalitis. We enrolled patients who were diagnosed with definite autoimmune encephalitis and underwent IVIg treatment at Seoul National University Hospital from 2012 to 2017. Patients were dichotomized according to serum albumin prior to IVIg administration with a cut-off level of 4...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29340243/urban-heat-island-effect-on-cicada-densities-in-metropolitan-seoul
#7
Hoa Q Nguyen, Desiree K Andersen, Yuseob Kim, Yikweon Jang
Background: Urban heat island (UHI) effect, the ubiquitous consequence of urbanization, is considered to play a major role in population expansion of numerous insects. Cryptotympana atrata and Hyalessa fuscata are the most abundant cicada species in the Korean Peninsula, where their population densities are higher in urban than in rural areas. We predicted a positive relationship between the UHI intensities and population densities of these two cicada species in metropolitan Seoul. Methods: To test this prediction, enumeration surveys of cicada exuviae densities were conducted in 36 localities located within and in the vicinity of metropolitan Seoul...
2018: PeerJ
https://www.readbyqxmd.com/read/29339660/laparoscopic-surgery-for-gallbladder-cancer-an-expert-consensus-statement
#8
Ho-Seong Han, Yoo-Seok Yoon, Anil K Agarwal, Giulio Belli, Osamu Itano, Andrew A Gumbs, Dong Sup Yoon, Chang Moo Kang, Seung Eun Lee, Toshifumi Wakai, Roberto I Troisi
BACKGROUND: Despite the increasing number of reports on the favorable outcomes of laparoscopic surgery for gallbladder cancer (GBC), there is no consensus regarding this surgical procedure. OBJECTIVE: The study aimed to develop a consensus statement on the application of laparoscopic surgery for GBC based on expert opinions. METHODS: A consensus meeting among experts was held on September 10, 2016, in Seoul, Korea. RESULTS: Early concerns regarding port site/peritoneal metastasis after laparoscopic surgery have been abated by improved preoperative recognition of GBC and careful manipulation to avoid bile spillage...
January 16, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29339658/survey-results-of-the-expert-meeting-on-laparoscopic-surgery-for-gallbladder-cancer-and-a-review-of-relevant-literature
#9
Yoo-Seok Yoon, Ho-Seong Han, Anil Agarwal, Giulio Belli, Osamu Itano, Andrew A Gumbs, Dong Sup Yoon, Chang Moo Kang, Seung Eun Lee, Toshifumi Wakai, Roberto I Troisi
BACKGROUND: Favorable outcomes of laparoscopic surgery for gallbladder cancer (GBC) have been reported; yet consensus on the indications and surgical techniques for laparoscopic surgery for GBC is lacking. OBJECTIVE: To evaluate the current status of laparoscopic surgery for GBC by analyzing the results of a survey of experts and by reviewing the relevant published literature. METHODS: Before an expert meeting was held on September 10, 2016 in Seoul, Korea, an international survey was undertaken of expert surgeons in the field of GBC surgery...
January 16, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29335100/risk-factors-for-and-management-of-pupillary-intraocular-lens-capture-after-intraocular-lens-transscleral-fixation
#10
Se Rang Choi, Ji Hoon Jeon, Joon Won Kang, Jang Won Heo
PURPOSE: To analyze risk factors and management of pupillary intraocular lens (IOL) capture after IOL transscleral fixation. SETTING: Department of Ophthalmology, Seoul National University Hospital, Seoul, South Korea. DESIGN: Retrospective case series. METHODS: A chart review was performed of patients who had transscleral fixation of IOLs between January 1, 2012, and December 31, 2013. Eyes were divided into 2 groups depending on whether the IOL was pupillary captured...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29335093/changes-in-biomechanically-corrected-intraocular-pressure-and-dynamic-corneal-response-parameters-before-and-after-transepithelial-photorefractive-keratectomy-and-femtosecond-laser-assisted-laser-in%C3%A2-situ-keratomileusis
#11
Hun Lee, Cynthia J Roberts, Tae-Im Kim, Renato Ambrósio, Ahmed Elsheikh, David Sung Yong Kang
PURPOSE: To evaluate the changes in biomechanically corrected intraocular pressure (IOP) and new dynamic corneal response parameters measured by a dynamic Scheimpflug analyzer before and after transepithelial photorefractive keratectomy (PRK) and femtosecond laser-assisted laser in situ keratomileusis (LASIK). SETTING: Yonsei University College of Medicine and Eyereum Eye Clinic, Seoul, South Korea. DESIGN: Retrospective case series. METHODS: Medical records of patients having transepithelial PRK or femtosecond-assisted LASIK were examined...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29334727/apob-apoa-i-ratio-is-independently-associated-with-carotid-atherosclerosis-in-type-2-diabetes-mellitus-with-well-controlled-ldl-cholesterol-levels
#12
Ji Eun Jun, Young Ju Choi, Yong-Ho Lee, Dae Jung Kim, Seok Won Park, Byung Wook Huh, Eun Jig Lee, Sun-Ha Jee, Kyu Yeon Hur, Sung Hee Choi, Kap Bum Huh
BACKGROUND/AIMS: This study aimed to investigate whether the apolipoprotein (Apo) B/ApoA-I ratio is associated with carotid intima-media thickness (CIMT) in type 2 diabetes mellitus (T2DM) subjects with low density lipoprotein cholesterol (LDL-C) levels less than 100 mg/dL. METHODS: This cross-sectional study included 845 subjects aged with T2DM 40 to 75 years who had visited Huh's Diabetes Center in Seoul, Republic of Korea for CIMT measurement. Traditional fasting lipid profiles, ApoB and ApoA-I levels were examined...
January 2018: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29333509/rate-and-association-of-lower-urinary-tract-infection-with-recurrence-after-transurethral-resection-of-bladder-tumor
#13
Byung Soo Kim, Bum Sik Tae, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Chang Wook Jeong
Purpose: To evaluate the rate of pyuria and bacteriuria after transurethral resection of bladder tumor (TURBT). Materials and Methods: We retrospectively evaluated data obtained from 363 patients who underwent TURBT between October 2012 and December 2013 at Seoul National University Hospital. Urinalysis and urine culture were assessed at 3, 6, 12, and 24 months postoperatively. Primary endpoint was the rate of bacteriuria (≥105/mL in a midstream) and pyuria (white blood cells ≥5/high-power field)...
January 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29333407/the-limited-role-of-serum-galactomannan-assay-in-screening-for-invasive-pulmonary-aspergillosis-in-allogeneic-stem-cell-transplantation-recipients-on-micafungin-prophylaxis-a-retrospective-study
#14
Ryul Kim, Youngil Koh, Dong-Yeop Shin, Pyoeng Gyun Choe, Nam Joong Kim, Sung-Soo Yoon, Myoung-Don Oh, Wan Beom Park, Inho Kim
Background: We evaluated the outcomes of serum galactomannan (GM) assay for the screening of invasive pulmonary aspergillosis (IPA) in allogeneic hematopoietic stem cell transplantation (alloHSCT) recipients while on primary antifungal prophylaxis (PAP). Methods: This study included patients with hematologic disorders who underwent alloHSCT from January 2013 to November 2015. Patients received routine PAP with fluconazole before 2014 and micafungin after 2014; serum GM tests were performed and retrospectively analyzed...
December 2017: Blood Research
https://www.readbyqxmd.com/read/29332372/measurement-and-modeling-of-indoor-radon-concentrations-in-residential-buildings
#15
Ji Hyun Park, Sungim Whang, Hyun Young Lee, Cheol-Min Lee, Dae Ryong Kang
Objectives: Radon, the primary constituent of natural radiation, is the second leading environmental cause of lung cancer after smoking. To confirm a relationship between indoor radon exposure and lung cancer, estimating cumulative levels of exposure to indoor radon for an individual or population is necessary. This study sought to develop a model for estimate indoor radon concentrations in Korea. Especially, our model and method may have wider application to other residences, not to specific site, and can be used in situations where actual measurements for input variables are lacking...
January 8, 2018: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/29331886/anti-cancer-effects-of-hnha-and-lenvatinib-by-the-suppression-of-emt-mediated-drug-resistance-in-cancer-stem-cells
#16
Yong Sang Lee, Seok-Mo Kim, Bup-Woo Kim, Ho Jin Chang, Soo Young Kim, Cheong Soo Park, Ki Cheong Park, Hang-Seok Chang
Anaplastic thyroid cancer (ATC) constitutes less than 2% of total thyroid cancers but accounts for 20-40% of thyroid cancer-related deaths. Cancer stem cell drug resistance represents a primary factor hindering treatment. This study aimed to develop targeted agents against thyroid malignancy, focusing on individual and synergistic effects of HNHA (histone deacetylase), lenvatinib (FGFR), and sorafenib (tyrosine kinase) inhibitors. Patients with biochemically and histologically proven papillary thyroid cancer (PTC) and ATC were included...
January 11, 2018: Neoplasia: An International Journal for Oncology Research
https://www.readbyqxmd.com/read/29331863/airborne-volatile-aromatic-hydrocarbons-at-an-urban-monitoring-station-in-korea-from-2013-to-2015
#17
Azmatullah Khan, Jan E Szulejko, Ki-Hyun Kim, Richard J C Brown
The concentrations of C6-C10 volatile aromatic hydrocarbons (AHCs) in air were measured at an urban air quality monitoring station in Jong-Ro, Seoul, Korea, between 2013 and 2015. Their temporal patterns (e.g., diurnal, intraweek, daily) were assessed individually and collectively as groups of benzene, toluene, ethylbenzene, styrene, and xylene (BTESX); total aliphatic hydrocarbon (TALHC: C2-C12); total aromatic hydrocarbon (TARHC: C6-C10); and total hydrocarbon (THC: C2-C12). The highest mean AHC concentrations over the 3-year study (in ppb (v/v)) were observed for toluene (6...
January 11, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29325562/increased-epicardial-adipose-tissue-thickness-is-a-predictor-of-new-onset-diabetes-mellitus-in-patients-with-coronary-artery-disease-treated-with-high-intensity-statins
#18
Jeehoon Kang, Young-Chan Kim, Jin Joo Park, Sehun Kim, Si-Hyuck Kang, Young Jin Cho, Yeonyee E Yoon, Il-Young Oh, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Tae-Jin Youn, In-Ho Chae, Dong-Ju Choi
BACKGROUND: Statins are widely used for lipid lowering in patients with coronary artery disease (CAD), but increasing evidence indicates an association between statin use and new-onset of diabetes mellitus (NODM). Epicardial adipose tissue (EAT) refers to the visceral fat surrounding the heart, which is associated with metabolic diseases. We sought to determine the association between EAT thickness and NODM in CAD patients treated with high-intensity statins. METHODS: We conducted a retrospective medical record review of CAD patients treated with high-intensity statins for at least 6 months after percutaneous coronary intervention performed between January 2009 and June 2013 at Seoul National University Bundang Hospital...
January 11, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29315276/identifying-dietary-patterns-associated-with-mild-cognitive-impairment-in-older-korean-adults-using-reduced-rank-regression
#19
Dayeon Shin, Kyung Won Lee, Mi-Hye Kim, Hung Ju Kim, Yun Sook An, Hae-Kyung Chung
Diet plays a crucial role in cognitive function. Few studies have examined the relationship between dietary patterns and cognitive functions of older adults in the Korean population. This study aimed to identify the effect of dietary patterns on the risk of mild cognitive impairment. A total of 239 participants, including 88 men and 151 women, aged 65 years and older were selected from health centers in the district of Seoul, Gyeonggi province, and Incheon, in Korea. Dietary patterns were determined using Reduced Rank Regression (RRR) methods with responses regarding vitamin B6, vitamin C, and iron intakes, based on both a one-day 24-h recall and a food frequency questionnaire...
January 9, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29312713/outcomes-of-perioperative-extracorporeal-membrane-oxygenation-use-in-patients-undergoing-lung-transplantation
#20
Joo Han Song, Ji Eun Park, Jin Gu Lee, Chang Young Lee, Kyung Sik Nam, Jee Won Suh, Anes Kim, Seung Hyun Lee, Hyun Chel Joo, Young Nam Youn, Song Yee Kim, Moo Suk Park, Hyo Chae Paik
Background: The aim of this single-center study is to review the transplant outcomes of patients receiving lung transplantation (LTx) using intraoperative extracorporeal membrane oxygenation (ECMO) according to the perioperative use of ECMO. Methods: We retrospectively reviewed the transplant outcomes of 107 consecutive patients who underwent LTx using intraoperative ECMO between March 2013 and August 2016 at Severance Hospital of Yonsei University (Seoul, Korea)...
December 2017: Journal of Thoracic Disease
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