Michelle A Bulterys, Irene Njuguna, Maureen King'e, Daisy Chebet, Hellen Moraa, Laurén Gomez, Alvin Onyango, Kenneth Malavi, Gladys Nzia, Martin Chege, Jillian Neary, Anjuli D Wagner, Kendall A Lawley, Dalton Wamalwa, Sarah Benki-Nugent, Grace John-Stewart
INTRODUCTION: Predictors of neurodevelopment among children who are HIV-exposed uninfected (CHEU) are poorly understood. METHODS: Mothers with and without HIV and their children were enrolled during 6-week postnatal care visits across seven sites in Kenya between March 2021 and June 2022. Infant neurodevelopment was assessed using the Malawi Developmental Assessment Tool, including social, language, fine motor and gross motor domains. We used multivariate linear mixed effects models to identify associations between 1-year neurodevelopment scores, HIV and antiretroviral therapy (ART) exposures, and household factors, adjusted for potential confounders and clustered by the site...
October 2023: Journal of the International AIDS Society