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https://www.readbyqxmd.com/read/28452100/pediatric-psoriasis-should-we-be-concerned-with-comorbidities-a-cross-sectional-study
#1
A Kelati, H Baybay, A Najdi, S Zinoune, F Z Mernissi
BACKGROUND: Similarly to psoriasis in adult, Recent research has linked psoriasis to several comorbidities in children. Our objective was to describe comorbidities associated with pediatric psoriasis, to investigate their relationship with psoriasis characteristics and severity, and to perform a review of the literature. METHODS: A cross-sectional study was performed on a sample of Moroccan psoriatic children, during two years 2014 -2016. RESULTS: 64 psoriatic children had metabolic comorbidities in association with psoriasis, 20 children had non-metabolic comorbidities and 76 children didn't have any comorbidities...
April 28, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28255730/medial-temporal-lobe-epilepsy-associated-with-hippocampal-sclerosis-is-a-distinctive-syndrome
#2
Young Joo No, Chiara Zavanone, Franck Bielle, Vi-Huong Nguyen-Michel, Yves Samson, Claude Adam, Vincent Navarro, Sophie Dupont
Epileptic syndromes are distinctive disorders with specific features, which when taken together, permit a specific diagnosis. There is actually a debate on that medial temporal lobe epilepsy with hippocampal sclerosis is an epileptic syndrome. To address this issue, we searched for discriminative semiological features between temporal lobe epilepsy patients with hippocampal sclerosis (TLE-HS patients or group 1), TLE patients with medial structural lesion other than hippocampal sclerosis or in MRI-negative cases with medial onset on further investigations (group 2) and lateral TLE patients (LTLE or group 3)...
March 2, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28250326/medication-and-driving-appropriate-interventions
#3
REVIEW
Masahito Hitosugi
 Sudden illness while driving has been identified as a major cause of vehicle collisions, accounting for approximately 1 in 10 collisions. Because most drivers who experience sudden illnesses while driving do not perform avoidance maneuvers, the improvement of drivers' health is being promoted as a traffic safety strategy. Although stroke, heart disease, and epilepsy are common causes of sudden illness, common symptoms, such as abdominal cramps, vertigo, and syncope can also cause problems during driving...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28245538/-improvement-in-hyperglysemia-following-unilateral-adrenalectomy-for-acth-independent-macronodular-adrenal-hyperplasia-aimah-a-case-report
#4
Junichi Ikeda, Kouei Muguruma, Takaaki Inoue, Teruhisa Nishida, Shigenari Kawakita, Takashi Murota, Haruyuki Ohsugi, Nae Takizawa, Hidefumi Kinoshita, Tadashi Matsuda, Amika Noda, Keita Utsunomiya
Adrenal corticotropin (ACTH) -independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of Cushing's syndrome. Bilateral adrenalectomy is the treatment of choice, but lifetime steroid replacement is essential. Here we report a case of AIMAH whose hyperglycemia was improved following unilateral adrenalectomy. A 42-year-old woman with serious intellectual disability and intractable epilepsy presented with polydipsia. Casual blood glucose and hemoglobin A1c (HbA1c) were 322 mg/dl and 8.5%, respectively...
January 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/27980744/abdominal-epilepsy-an-uncommon-cause-of-chronic-and-recurrent-abdominal-pain-a-case-report
#5
Bonaventura C T Mpondo, Godfrey Mwasada, Azan A Nyundo
Abdominal epilepsy is an uncommon cause of paroxysmal abdominal pain. It is relatively common in children, but very rare in adults. We report a case of 38-year-old, who reported with recurrent abdominal pain for 2 years. Electroencephalography confirmed the diagnosis; he responded well to carbamazepine and remains symptom-free on follow-up.
December 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27917225/abdominal-epilepsy-as-an-unusual-cause-of-abdominal-pain-a-case-report
#6
Yilmaz Yunus, Ustebay Sefer, Ulker Ustebay Dondu, Ozanli Ismail, Ehi Yusuf
INTRODUCTION: Abdominal pain, in etiology sometimes difficult to be defined, is a frequent complaint in childhood. Abdominal epilepsy is a rare cause of abdominal pain. OBJECTIVES: In this article, we report on 5 year old girl patient with abdominal epilepsy. METHODS: Some investigations (stool investigation, routine blood tests, ultrasonography (USG), electrocardiogram (ECHO) and electrocardiograpy (ECG), holter for 24hr.) were done to understand the origin of these complaints; but no abnormalities were found...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27891434/abdominal-epilepsy-in-an-adult-a-diagnosis-often-missed
#7
Devavrat G Harshe, Sneha D Harshe, Gurudas R Harshe, Gayatri G Harshe
Abdominal Epilepsy (AE) is a variant of temporal lobe epilepsy and is commonly seen in pediatric age group. There are however, multiple reports of abdominal epilepsy in adolescents and even in adults. Chronic and recurrent gastrointestinal symptoms with one or more neuropsychiatric manifestations are often the presenting picture for a patient with AE. Such patients therefore, are more likely to consult a general practioner, a physician, a surgeon or a gastroenterologist than consulting a psychiatrist or a neurologist...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27876238/thermography-examination-of-abdominal-area-skin-temperatures-in-individuals-with-and-without-focal-onset-epilepsy
#8
Hollis H King, Charles Thomas Cayce, Jeph Herrin
Early osteopathic theory and practice, and the work of the medical intuitive Edgar Cayce suggested that the abdominal areas of individuals with epilepsy would manifest "cold spots." The etiology for this phenomenon was thought to be abdominal adhesions caused by inflammation and viscero-somatic reflexes caused by adhesions or injury to visceral or musculoskeletal system structures. Indeed, until that advent of electroencephalography in the 1930s, medical practice regarding epilepsy focused on abdominal neural and visceral structures...
January 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/27866088/is-ketogenic-diet-treatment-hepatotoxic-for-children-with-intractable-epilepsy
#9
Nur Arslan, Orkide Guzel, Engin Kose, Unsal Yılmaz, Pınar Kuyum, Betül Aksoy, Tansel Çalık
PURPOSE: Long-term ketogenic diet (KD) treatment has been shown to induce liver steatosis and gallstone formation in some in vivo and clinical studies. The aim of this retrospective study was to evaluate the hepatic side effects of KD in epileptic children. METHOD: A total of 141 patients (mean age: 7.1±4.1years [2-18 years], 45.4% girls), receiving KD at least one year for intractable epilepsy due to different diagnoses (congenital brain defects, GLUT-1 deficiency, West syndrome, tuberous sclerosis, hypoxic brain injury, etc...
December 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/27792104/neurocutaneous-melanosis-presenting-as-cavernous-hemangioma-persistent-abdominal-pain
#10
Keman Liao, Shuanglin Que, Yongming Qiu, Shilei Zhang, Zhihua Chen
Neurocutaneous melanosis (NCM) is a rare congenital syndrome characterized by the presence of multiple congenital melanocytic nevi and the proliferation of melanocytes in the central nervous system. The authors present a 9-year-old Chinese boy whose clinical manifestations are intermittent headache for 2 months and persistent abdominal pain for 10 days. 3D-reconstruction computed tomography angiography image, digital subtraction angiography, and magnetic resonance imaging plus angiography (MRI+MRA) examinations results suggested that cavernoma at left frontal lobe potentially associated with hemorrhage...
March 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27481338/pediatric-lead-poisoning-from-folk-prescription-for-treating-epilepsy
#11
Xiao-Lan Ying, Jian Xu, Morri Markowitz, Chong-Huai Yan
BACKGROUND: A case of lead poisoning resulting from the ingestion of a folk remedy for treating epilepsy is reported. RESULTS: The initial blood lead concentration of this 6-y-old boy was 63.6μg/dl upon admission. He presented with abdominal pain, constipation, and irritability. The patient's liver function tests were significantly increased. Through chelation therapy, the blood lead concentration dropped markedly and clinical symptoms greatly improved. His blood and urine samples were collected for the kinetic analysis of lead elimination...
October 1, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27375140/novel-mutation-of-the-notch3-gene-in-a-polish-family-with-cadasil
#12
Julia Buczek, Beata Błażejewska-Hyżorek, Agnieszka Cudna, Małgorzata Lusawa, Eliza Lewandowska, Iwona Kurkowska-Jastrzębska, Anna Członkowska
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited small blood vessels disease caused by mutations in the gene encoding the neurogenic locus notch homolog protein 3 (NOTCH 3). We present a Polish family with a previously unreported novel mutation in exon 12 c.1851C>C/G of the NOTCH3 gene and varying disease expression. One of the two family members with the confirmed mutation presented with all the main CADASIL symptoms; while, his affected father was nearly asymptomatic...
July 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/27149672/behavioral-ventilatory-and-thermoregulatory-responses-to-hypercapnia-and-hypoxia-in-the-wistar-audiogenic-rat-war-strain
#13
Érica Maria Granjeiro, Glauber S F da Silva, Humberto Giusti, José Antonio Oliveira, Mogens Lesner Glass, Norberto Garcia-Cairasco
INTRODUCTION: We investigated the behavioral, respiratory, and thermoregulatory responses elicited by acute exposure to both hypercapnic and hypoxic environments in Wistar audiogenic rats (WARs). The WAR strain represents a genetic animal model of epilepsy. METHODS: Behavioral analyses were performed using neuroethological methods, and flowcharts were constructed to illustrate behavioral findings. The body plethysmography method was used to obtain pulmonary ventilation (VE) measurements, and body temperature (Tb) measurements were taken via temperature sensors implanted in the abdominal cavities of the animals...
2016: PloS One
https://www.readbyqxmd.com/read/27110310/assessment-of-coeliac-disease-prevalence-in-patients-with-down-syndrome-in-poland-a-multi-centre-study
#14
Anna Szaflarska-Popławska, Anetta Soroczyńska-Wrzyszcz, Ewa Barg, Jan Józefczuk, Bartosz Korczowski, Urszula Grzybowska-Chlebowczyk, Sabina Więcek, Bożena Cukrowska
INTRODUCTION: The results of studies assessing whether patients with Down syndrome have increased risk of coeliac disease are contradictory. The prevalence of coeliac disease in patients with Down syndrome is estimated at a wide range between 1% to as much as 18.6%. AIM: To assess coeliac disease prevalence in patients with Down syndrome in Poland. MATERIAL AND METHODS: The study enrolled 301 patients with Down syndrome from six centres in Poland (Wroclaw, Sandomierz, Rzeszow, Grudziadz, Katowice, and Bydgoszcz)...
2016: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/27084209/auras-in-patients-with-temporal-lobe-epilepsy-and-mesial-temporal-sclerosis
#15
Ali A Asadi-Pooya, Maromi Nei, Ashwini Sharan, Michael R Sperling
We investigated auras in patients with drug-resistant temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS). We also investigated the clinical differences between patients with MTS and abdominal auras and those with MTS and non-mesial temporal auras. All patients with drug-resistant TLE and unilateral MTS who underwent epilepsy surgery at Jefferson Comprehensive Epilepsy Center from 1986 through 2014 were evaluated. Patients with good postoperative seizure outcome were investigated. One hundred forty-nine patients (71 males and 78 females) were studied...
May 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27034860/a-case-of-primary-hypoparathyroidism-presenting-with-acute-kidney-injury-secondary-to-rhabdomyolysis
#16
Abdullah Sumnu, Zeki Aydin, Meltem Gursu, Sami Uzun, Serhat Karadag, Egemen Cebeci, Savas Ozturk, Rumeyza Kazancioglu
Hypoparathyroidism is the most common cause of symmetric calcification of the basal ganglia. Herein, a case of primary hypoparathyroidism with severe tetany, rhabdomyolysis, and acute kidney injury is presented. A 26-year-old male was admitted to the emergency clinic with leg pain and cramps, nausea, vomiting, and decreased amount of urine. He had been treated for epilepsy for the last 10 years. He was admitted to the emergency department for leg pain, cramping in the hands and legs, and agitation multiple times within the last six months...
2016: Case Reports in Nephrology
https://www.readbyqxmd.com/read/27002245/metabolic-syndrome-in-young-adults-with-epilepsy
#17
Sruthi S Nair, S Harikrishnan, P Sankara Sarma, Sanjeev V Thomas
PURPOSE: Persons with epilepsy have higher cardiovascular mortality and morbidity compared to general population and alteration of their biochemical milieu is one of the proposed mechanisms. We aimed to study the prevalence of metabolic syndrome and cardiovascular risk factors in young adults with epilepsy and the association with antiepileptic drug use. METHOD: An observational study was conducted in persons with epilepsy aged 20-49 years using antiepileptic drugs regularly for the previous three years...
April 2016: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/26949154/analgesic-opioid-use-in-a-health-insured-epilepsy-population-during-2012
#18
A N Wilner, B K Sharma, A R Thompson, A Krueger
RATIONALE: Analgesic opioid use has increased dramatically in the general population. Although opioid analgesics are not indicated for the treatment of epilepsy, frequent opioid use has been reported in the epilepsy population. It is not clear whether comorbid disorders and/or epilepsy-associated injuries due to seizures foster opioid use. Our primary objective was to compare the prevalence of analgesic opioid use in an insured patient population with epilepsy to a matched control population without epilepsy...
April 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/26868277/various-clinical-conditions-can-mimic-crimean-congo-hemorrhagic-fever-in-pediatric-patients-in-endemic-regions
#19
Soner S Kara, Duygu Kara, Ali Fettah
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne disease with high mortality. Many disorders can mimic CCHF. It is important to recognize the condition and to perform differential diagnosis in endemic countries. Twenty-one children aged 18 years or less with a preliminary diagnosis of CCHF were retrospectively evaluated. Real-time PCR and a confirmatory indirect immunofluorescence assay for negative results were performed. The diagnoses determined that 9 patients had (42.9%) CCHF; 7 patients had (33.3%) viral upper respiratory tract infections (URTI); 2 patients had (9...
September 2016: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/26755195/friedreich-ataxia-and-nephrotic-syndrome-a-series-of-two-patients
#20
Julianna E Shinnick, Charles J Isaacs, Sharon Vivaldi, Kimberly Schadt, David R Lynch
BACKGROUND: Friedreich Ataxia (FRDA) is a neurodegenerative disorder characterized by gait and balance abnormalities, sensory loss, weakness, loss of reflexes, and ataxia. Previously, two cases of FRDA and Nephrotic Syndrome (NS) have been reported. Here we report two additional individuals with NS and FRDA, providing further evidence for a possible connection between the two diseases and focusing on the neuromuscular responsiveness of one individual to corticosteroid treatment, an effect not previously described in FRDA...
2016: BMC Neurology
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