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sporotrichosis

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https://www.readbyqxmd.com/read/27914747/sporothrix-schenckii-sensu-lato-identification-in-fragments-of-skin-lesion-cultured-in-nnn-medium-for-differential-diagnosis-of-cutaneous-leishmaniasis
#1
Liliane de Fátima Antonio, Maria Inês Fernandes Pimentel, Marcelo Rosandiski Lyra, Maria de Fátima Madeira, Luciana de Freitas Campos Miranda, Rodrigo Almeida Paes, Fábio Brito-Santos, Maria Helena Galdino Figueredo Carvalho, Armando de Oliveira Schubach
Eighty-nine patients with clinical suspicion of leishmaniasis were referred for differential diagnosis. Sporothrix schenckii sensu lato was isolated in Novy-MacNeal-Nicolle + Schneider media in 98% of 64 patients with final diagnosis of sporotrichosis. This medium may be suitable for diagnosis of sporotrichosis in areas where cutaneous leishmaniasis is also endemic.
November 15, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27861481/-presence-of-lactoferrin-lf-in-lymphocutaneous-sporotrichosis-yeast-bound-antimicrobial-peptide
#2
Alejandro Palma-Ramos, Laura E Castrillón-Rivera, María Elisa Vega-Mémije, Roberto Arenas-Guzmán, Lucía Rangel-Gamboa
: Sporotrichosis is a common subcutaneous mycosis in Latin America, produced by dimorphic fungi belong to Sporothrix schenckii complex of cryptic species. Infection is acquired by traumatic inoculation with contaminated organic material. Host immune response includes polymorphonuclear neutrophils chemotaxis and release of granular components. Lactoferrin is a protein member of the transferrin family of iron-binding proteins, present inside polymorphonuclear granular structure, and has been reported to affect growth and development of infectious agents, including fungal organisms...
November 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27856302/anti-inflammatory-activity-of-vismia-guianensis-aubl-pers-extracts-and-antifungal-activity-against-sporothrix-schenckii
#3
A H Oliveira, G G de Oliveira, F Carnevale Neto, D F Portuondo, A Batista-Duharte, I Z Carlos
ETHNOPHARMACOLOGICAL RELEVANCE: Vismia guianensis (Aubl.) Pers. is traditionally used in North and Northeast of Brazil for the treatment of dermatomycoses. Since the strategy associating immunomodulators with antifungal drugs seems to be promissory to improve the treatment efficacy in fungal infections, we aimed to investigate the antifungal activity of V. guianensis ethanolic extract of leaves (VGL) and bark (VGB) against Sporothrix schenckii ATCC 16345 and their antinflammatory activities...
November 14, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27771622/refractory-sporotrichosis-due-to-sporothrix-brasiliensis-in-humans-appears-to-be-unrelated-to-in-vivo-resistance
#4
Rodrigo Almeida-Paes, Manoel Marques Evangelista Oliveira, Dayvison Francis Saraiva Freitas, Antônio Carlos Francesconi do Valle, Maria Clara Gutierrez-Galhardo, Rosely Maria Zancopé-Oliveira
Sporotrichosis is a subacute to chronic infection caused by members of the Sporothrix schenckii complex. Itraconazole is the first choice antifungal drug for treating this infection, with terbinafine and potassium iodide as alternatives and amphotericin B used in cases of severe infections. Correlation of antifungal susceptibility data with the clinical outcome of the patients is scarce. The aim of this study was to correlate clinical and mycological data in patients with refractory sporotrichosis. In this work, antifungal susceptibilities, determined according to the reference M38-A2 CLSI protocol, of 25 Sporothrix strains, isolated from seven human cases of sporotrichosis with adversities in the treatment, are presented...
October 22, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27742285/invasive-fungal-disease-in-renal-transplant-recipients-at-a-brazilian-center-local-epidemiology-matters
#5
L F A Guimarães, M Halpern, A S de Lemos, E F de Gouvêa, R T Gonçalves, M A A da Rosa Santos, M Nucci, G Santoro-Lopes
INTRODUCTION: Invasive fungal disease (IFD) is an important complication after solid organ transplantation (SOT). A marked geographic variation in the epidemiology of IFD after kidney transplantation (KT) has been suggested by the results of previous studies. Nevertheless, data from Latin American centers are scarce. OBJECTIVE: This study sought to describe the epidemiology of IFD at a Brazilian KT center. METHODS: This study was a retrospective single-center cohort study that included patients who underwent KT between 1998 and 2009 and were followed up until July 2015...
September 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27663926/tinea-on-a-tattoo
#6
Alexandru Oanţă, Marius Irimie
In the last twenty years, the prevalence of individuals with tattoos in the general population has increased in Europe (1) as well as in Australia (2) and the United States of America (3). A series of complications such as acute inflammatory reactions, allergic contact dermatitis (4,5), photoinduced, lichenoid, and granulomatous reactions (6, 7), pseudolymphoma (8), pseudoepitheliomatous hyperplasia (9), skin infections (6), and skin cancers (10) may occur on tattoos. Infectious complications on tattoos include bacterial infections (pyoderma, leprosy, syphilis, cutaneous tuberculosis, mycobacteriosis) (11-14), viral infections (molluscum contagiosum, warts, herpes simplex, hepatitis B and C) (15-17), and fungal infections (sporotrichosis, dermatophytosis) (18,19)...
August 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27648881/sporotrichosis-associated-hospitalizations-united-states-2000-2013
#7
Jeremy A W Gold, Gordana Derado, Rajal K Mody, Kaitlin Benedict
To determine frequency and risk for sporotrichosis-associated hospitalizations, we analyzed the US 2000-2013 National (Nationwide) Inpatient Sample. An estimated 1,471 hospitalizations occurred (average annual rate 0.35/1 million persons). Hospitalizations were associated with HIV/AIDS, immune-mediated inflammatory diseases, and chronic obstructive pulmonary disease. Although rare, severe sporotrichosis should be considered for at-risk patients.
October 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27639705/antifungal-and-immunomodulatory-activity-of-a-novel-cochleate-for-amphotericin-b-delivery-against-sporothrix-schenckii
#8
A Batista-Duharte, M Lastre, B Romeu, D L Portuondo, D Téllez-Martínez, F A Manente, O Pérez, I Z Carlos
INTRODUCTION: Sporotrichosis is an emergent subcutaneous mycoses caused by species of the Sporothrix schenckii complex. Amphotericin B (AmB) remains the main antifungal drug for the treatment of systemic infections, but its use is limited by toxicity reasons. AFCo3 is a novel cochleate containing detoxified LPS, which exhibits drug delivery and immunomodulating properties. Here, AFCo3 was used as the vehicle for AmB to evaluate the immunomodulatory and antifungal efficacy against S. schenckii in vitro and in vivo...
September 15, 2016: International Immunopharmacology
https://www.readbyqxmd.com/read/27635048/whole-genome-sequencing-and-in-silico-analysis-of-two-strains-of-sporothrix-globosa
#9
Lilin Huang, Wenchao Gao, Domenico Giosa, Giuseppe Criseo, Jing Zhang, Tailong He, Xiaowen Huang, Jiufeng Sun, Yao Sun, Jiamin Huang, Yunqing Zhang, Balazs Brankovics, Fabio Scordino, Enrico D'Alessandro, Anne van Diepeningen, Sybren de Hoog, Huaiqiu Huang, Orazio Romeo
Sporothrix globosa is a thermo-dimorphic fungus belonging to a pathogenic clade that also includes Sporothrix schenckii, which causes human and animal sporotrichosis. Here, we present the first genome assemblies of two S. globosa strains providing data for future comparative genomic studies in pathogenic Sporothrix species.
September 15, 2016: Genome Biology and Evolution
https://www.readbyqxmd.com/read/27622513/is-there-any-difference-between-the-in-situ-and-systemic-il-10-and-ifn-%C3%AE-production-when-clinical-forms-of-cutaneous-sporotrichosis-are-compared
#10
Fernanda N Morgado, Armando O Schubach, Maria Inês Pimentel, Marcelo R Lyra, Érica C F Vasconcellos, Claudia M Valete-Rosalino, Fátima Conceição-Silva
Fungus of the Sporothrix schenckii complex can produce skin lesions in humans, commonly lymphocutaneous (LC) and fixed (F) forms of sporotrichosis. Some authors have suggested that clinical forms are influenced by differences in virulence and genetic profile of isolates. But little is known about the role of immune response in determining the clinical outcome of sporotrichosis. To verify the profile of systemic and in situ IFN-γ and IL-10 expression in sporotrichosis patients, and consequently to detect any difference between the two compartments and/or clinical presentation, we quantified the number of IFN-γ and IL-10 producer peripheral blood mononuclear cells stimulated with S...
2016: PloS One
https://www.readbyqxmd.com/read/27616802/the-divorce-of-sporothrix-and-ophiostoma-solution-to-a-problematic-relationship
#11
Z W de Beer, T A Duong, M J Wingfield
One of the causal agents of human sporotrichosis, Sporothrix schenckii, is the type species of the genus Sporothrix. During the course of the last century the asexual morphs of many Ophiostoma spp. have also been treated in Sporothrix. More recently several DNA-based studies have suggested that species of Sporothrix and Ophiostoma converge in what has become known as Ophiostoma s. lat. Were the one fungus one name principles adopted in the Melbourne Code to be applied to Ophiostoma s. lat., Sporothrix would have priority over Ophiostoma, resulting in more than 100 new combinations...
2016: Studies in Mycology
https://www.readbyqxmd.com/read/27613208/mortality-from-fungal-diseases-in-the-us-air-force-from-1970-to-2013
#12
Richard K Kugblenu, Will K Reeves
We review a unique set of documents, death certificates, catalogued in the US Air Force Mortality Registry, which tracks deaths for current and retired Air Force service members. We screened the records for all deaths caused by fungal diseases between 1970 and 2013. There were 216 deaths caused by a variety of diseases such as aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis, pneumocystosis, sporotrichosis, and zygomycosis. The single most common identified cause of death was opportunistic candidiasis...
October 2016: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/27598646/osteomyelitis-caused-by-sporothrix-schenckii-in-an-immunocompetent-patient
#13
Laura Cunha Ferreira, Paulo Feijo Barroso, Elise Tonomura, Tiyomi Akiti, Káris Maria de Pinho Rodrigues
Sporotrichosis is the most common subcutaneous mycosis in South America and its association with zoonotic transmission remains a relevant public health problem in Rio de Janeiro, Brazil. The disease most commonly presents as subacute or chronic cutaneous lesions, although dissemination to various organs and systems occurs in rare cases, mainly in immunosuppressed individuals. This report describes a case of sporotrichosis with severe bone and subcutaneous damage in an immunocompetent patient who did not exhibit the characteristic skin lesions of sporotrichosis, including ulcers, nodules, and lymphangitis...
July 2016: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/27598283/-epidemiological-clinical-and-laboratory-characterization-of-sporotrichosis-in-patients-of-a-tertiary-care-hospital-in-lima-peru-from-1991-to-2014
#14
James A Oyarce, Coralith García, Jorge Alave, Beatriz Bustamante
BACKGROUND: Sporothricosis is endemic in numerous Latin American countries and the rest of the world. In Peru is concentrated in regions with warm and humid climate being little known in the rest of the country. AIM: To describe the epidemiological, clinical and laboratory characteristics of patients diagnosed of sporotrichosis in a tertiary-care level hospital in Lima, Peru from 1991 to 2014. METHODS: This was a retrospective, case series...
June 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27595209/sporotrichosis-long-term-treatment-and-follow-up-in-a-diabetic-patient-from-southern-italy
#15
Serena Lembo, Teresa Cirillo, Claudio Marasca, Viviana Lo Conte, Claudio Lembo, Anna Balato, Giuseppe Monfrecola
No abstract text is available yet for this article.
October 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27583270/disseminated-sporotrichosis-in-an-immunocompetent-patient
#16
Kareem Hassan, Tolga Turker, Tirdad Zangeneh
Sporothrix schenckii, the causative agent of sporotrichosis, is a relatively rare infection. Local infection usually occurs through direct inoculation of the organism through the skin; disseminated disease is rarely seen. This article describes a case of disseminated sporotrichosis in a middle-aged man without the commonly seen risk factors for dissemination.
2016: Case Reports in Plastic Surgery & Hand Surgery
https://www.readbyqxmd.com/read/27581775/studies-in-phylogeny-development-of-rapid-identificationmethods-antifungal-susceptibility-and-growth-rates-of-clinical-strains-of-sporothrix-schenckii-complex-in-japan
#17
Rumi Suzuki, Alimu Yikelamu, Reiko Tanaka, Ken Igawa, Hiroo Yokozeki, Takashi Yaguchi
Sporotrichosis is a fungal infection caused by the Sporothrix species, which have distinct virulence profiles and geographic distributions. We performed a phylogenetic study in strains morphologically identified as Sporothrix schenckii from clinical specimens in Japan, which were preserved at the Medical Mycology Research Center, Chiba University. In addition, we examined the in vitro antifungal susceptibility and growth rate to evaluate their physiological features. Three hundred strains were examined using sequence analysis of the partial calmodulin gene, or polymerase chain reaction(PCR)method using newly designed species-specific primers; 291 strains were Sporothrix globosa and 9 strains were S...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27581121/adamantylidene-substituted-alkylphosphocholine-tcan26-is-more-active-against-sporothrix-schenckii-than-miltefosine
#18
Luana Pereira Borba-Santos, Kelly Ishida, Theodora Calogeropoulou, Wanderley de Souza, Sonia Rozental
Sporotrichosis is the most frequent subcutaneous mycosis in the world and its increasing incidence has led to the search for new therapeutic options for its treatment. In this study, we demonstrated that three structural analogues of miltefosine (TCAN26, TC19, and TC70) showed inhibitory activity against Sporothrix schenckii sensu stricto and that TCAN26 was more active in vitro than miltefosine against several isolates. Scanning electron microscopy showed that S. schenckii exposure to TCAN26 resulted in cells that were slightly more elongated than untreated cells...
August 2016: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/27579758/disseminated-cutaneous-sporotrichosis-associated-with-ocular-lesion-in-an-immunocompetent-patient
#19
Karina Bittencourt Medeiros, Luana Gomes Landeiro, Lucia Martins Diniz, Aloísio Falqueto
A 59-year-old female patient, previously healthy, immunocompetent, presented left bulbar conjunctiva lesions and nodular-ulcerated lesions on the arms and cervical region, besides left cervical and retroauricular lymphadenopathy. She had previous contact with domestic cats that excoriated her face. The diagnosis was conclusive of disseminated sporotrichosis through clinical and epidemiological history and cultures of skin and ocular secretions. It evolved with good response to oral antifungal therapy.
July 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27521671/clinical-features-of-10-cases-of-eyelid-sporotrichosis-in-jilin-province-northeast-china
#20
Bin Fan, Jin-Feng Wang, Bin Zheng, Xin-Zhu Qi, Jing-Yao Song, Guang-Yu Li
OBJECTIVE: Sporotrichosis is a common subcutaneous mycosis caused by an infection with dimorphic fungus Sporothrix schenckii. We present a series of patients with eyelid sporotrichosis and study the clinical and histopathological presentation, microbiology, treatment options, and outcome. METHODS: A retrospective case-series study of patients with a clinical diagnosis of eyelid sporotrichosis. Records were examined to obtain information regarding patient demographics, presenting symptoms and signs, histopathological examination, microbiology, management, and outcomes...
August 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
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