keyword
MENU ▼
Read by QxMD icon Read
search

sporotrichosis

keyword
https://www.readbyqxmd.com/read/29147593/rapidly-progressive-disseminated-sporotrichosis-as-the-first-presentation-of-hiv-infection-in-a-patient-with-a-very-low-cd4-cell-count
#1
Isis Cristine Morávia Ribeiro de Oliveira-Esteves, Guilherme Almeida Rosa da Silva, Walter de Araujo Eyer-Silva, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Carlos José Martins, Rogério Neves-Motta, Marcelo Costa Velho Mendes de Azevedo, Dario José Hart Pontes Signorini, Jorge Francisco da Cunha Pinto, Lívia Machado Moura, Rafael Jacyntho Laterça, Diogo Raphael Garcia de Oliveira Pereira, Isabela Vieira do Lago, Fernando Raphael de Almeida Ferry
Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms. These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29080316/sporotrichosis-transmitted-by-a-cockatiel-nymphicus-hollandicus
#2
V Fichman, I D F Gremião, A A V Mendes-Júnior, F M S Sampaio, D F S Freitas, M M E Oliveira, R Almeida-Paes, A C F Valle, M C Gutierrez-Galhardo
Sporotrichosis is caused by dimorphic, pathogenic species from the genus Sporothrix, which are found in nature as saprophytes in decaying vegetation and soil. Classic transmission occurs after traumatic inoculation while manipulating contaminated plant material, and zoonotic transmission is uncommon. The genus Sporothrix contains relevant species with diverse clinical features, infection routes and virulence traits. This article is protected by copyright. All rights reserved.
October 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29058171/cavitary-pulmonary-sporotrichosis-case-report-and-literature-review
#3
Florencia D Rojas, Mariana S Fernández, Juan Manuel Lucchelli, Dora Lombardi, José Malet, María Eugenia Vetrisano, María Emilia Cattana, María de Los Ángeles Sosa, Gustavo Giusiano
A case of cavitary pulmonary sporotrichosis without mucocutaneous involvement caused by Sporothrix schenckii is reported in a sexagenarian woman with a long smoking history. The patient was hospitalized for septic shock with multiorgan failure from a respiratory focus. The diagnosis was delayed due to the fungal etiological agent was not initially considered in the differential diagnosis. A good clinical and radiological evolution was obtained with the antifungal therapy. Occasional cases of primary pulmonary sporotrichosis have been reported in the literature...
December 2017: Mycopathologia
https://www.readbyqxmd.com/read/29033815/cutaneous-nocardiosis-simulating-cutaneous-lymphatic-sporotrichosis
#4
Pedro Secchin, Beatriz Moritz Trope, Larissa Araujo Fernandes, Glória Barreiros, Marcia Ramos-E-Silva
Sporotrichosis is the subcutaneous mycosis caused by several species of the Sporothrix genus. With worldwide occurrence, the State of Rio de Janeiro is presently undergoing a zoonotic sporotrichosis epidemic. The form of lymphocutaneous nocardiosis is rare, being caused especially by Nocardia brasiliensis. It appears as a nodular or ulcerated lesion, with multiple painful erythematous nodules or satellite pustules distributed along the lymphatic tract, similar to the lymphocutaneous variant of sporotrichosis...
May 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/29026615/an-unusual-cutaneous-infection-caused-by-mycobacterium-marinum
#5
Federica Veronese, Elisa Zavattaro, Pamela Farinelli, Enrico Colombo, Paola Savoia
Introduction.Mycobacterium marinum is a non-tubercular mycobacterium residing in fresh or salt water (in tropical or temperate areas); it is a fish and human pathogen, and in immunocompromised patients can cause severe cutaneous and subcutaneous infections. Case presentation. A 46-year-old white man who underwent immunosuppressive therapy was admitted to our department in May 2016 for skin lesions previously diagnosed as 'unusual erysipelas'. We rejected the hypothesis of erysipelas, due to the clinical features, and our diagnostic hypotheses were oriented towards sporotrichosis, atypical mycobacteriosis, cutaneous tuberculosis and cutaneous sarcoidosis...
April 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29018254/genetic-variation-of-sporothrix-globosa-isolates-from-diverse-geographic-and-clinical-origins-in-china
#6
Lipei Zhao, Yan Cui, Yu Zhen, Lei Yao, Ying Shi, Yang Song, Ruili Chen, Shanshan Li
Sporothrix globosa is the main causative agent of sporotrichosis, a common mycosis that usually affects the skin, in China. Despite increasing efforts in the molecular identification of this fungal pathogen, its modes of transmission and epidemiology remain poorly understood. The goals of this study were to assess the genetic diversity of S. globosa using amplified fragment length polymorphism (AFLP) analysis and to assess the correlation of AFLP profiles with the geographic origins, growth rates, clinical forms, and antifungal susceptibilities of S...
October 11, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28989052/in-silico-analysis-of-cytochrome-p450-monooxygenases-in-chronic-granulomatous-infectious-fungus-sporothrix-schenckii-special-focus-on-cyp51
#7
Retshedisitswe Godfrey Matowane, Lukasz Wieteska, Hans Denis Bamal, Ipeleng Kopano Rosinah Kgosiemang, Mari Van Wyk, Nessie Agnes Manume, Sara Mohamed Hasaan Abdalla, Samson Sitheni Mashele, Dominik Gront, Khajamohiddin Syed
Sporotrichosis is an emerging chronic, granulomatous, subcutaneous, mycotic infection caused by Sporothrix species. Sporotrichosis is treated with the azole drug itraconazole as ketoconazole is ineffective. It is a well-known fact that azole drugs act by inhibiting cytochrome P450 monooxygenases (P450s), heme-thiolate proteins. To date, nothing is known about P450s in Sporothrix schenckii and the molecular basis of its resistance to ketoconazole. Here we present genome-wide identification, annotation, phylogenetic analysis and comprehensive P450 family-level comparative analysis of S...
October 5, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28984226/clotrimazole-is-highly-effective-in-vitro-against-feline-sporothrix-brasiliensis-isolates
#8
Thalita Gagini, Luana Pereira Borba-Santos, Anderson Messias Rodrigues, Zoilo Pires de Camargo, Sonia Rozental
PURPOSE: Sporothrix brasiliensis, the most virulent species in the Sporothrix schenckii complex, is responsible for the ongoing epidemics of human and animal sporotrichosis in Brazil. Feline outbreaks are usually driven by S. brasiliensis and followed by extensive transmission to humans. Itraconazole is the first-line treatment for both feline and human sporotrichosis; however, reduced sensitivity is an emerging issue. Thus, we investigated the effect of the widely used antifungal clotrimazole - alone or in combination with itraconazole - against the pathogenic (yeast) form of feline and human S...
October 6, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28972025/differences-in-clinical-ocular-outcomes-between-exogenous-and-endogenous-endophthalmitis-caused-by-sporothrix-a-systematic-review-of-published-literature
#9
Max Carlos Ramírez Soto
BACKGROUND: Sporotrichosis is an implantation mycosis caused by Sporothrix species prevalent worldwide, which occasionally can also result in intraocular infection presenting as an exogenous or endogenous infection (disseminated sporotrichosis). Knowledge in its clinical recognition and management is limited. AIMS: To systematically review and analyse data from published literature with a view to comparing clinical outcomes between exogenous and endogenous endophthalmitis caused by Sporothrix...
September 28, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28966608/tacrolimus-increases-the-effectiveness-of-itraconazole-and-fluconazole-against-sporothrix-spp
#10
Luana P Borba-Santos, Leandro F Reis de Sá, Juliene A Ramos, Anderson M Rodrigues, Zoilo P de Camargo, Sonia Rozental, Antonio Ferreira-Pereira
Calcineurin inhibitors - such as the clinically used drug tacrolimus - are active against important fungal pathogens, particularly when combined with azoles. However, tacrolimus has not been tested against sporotrichosis, an endemic subcutaneous mycosis with worldwide distribution. Here, we evaluated the activity of tacrolimus and cyclosporine A in vitro - as monotherapy and in combination with itraconazole or fluconazole - against yeasts of Sporothrix brasiliensis and S. schenckii, the main sporotrichosis agents in Brazil...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28919888/the-sporothrix-schenckii-gene-encoding-for-the-ribosomal-protein-l6-has-constitutive-and-stable-expression-and-works-as-an-endogenous-control-in-gene-expression-analysis
#11
Elías Trujillo-Esquivel, José A Martínez-Álvarez, Diana M Clavijo-Giraldo, Nahúm V Hernández, Alberto Flores-Martínez, Patricia Ponce-Noyola, Héctor M Mora-Montes
Sporothrix schenckii is one of the causative agents of sporotrichosis, a worldwide-distributed mycosis that affects humans and other mammals. The interest in basic and clinical features of this organism has significantly increased in the last years, yet little progress in molecular aspects has been reported. Gene expression analysis is a set of powerful tools that helps to assess the cell response to changes in the extracellular environment, the genetic networks controlling metabolic pathways, and the adaptation to different growth conditions...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28855477/the-current-status-of-feline-sporotrichosis-in-malaysia
#12
Han Hock Siew
Feline sporotrichosis has been reported in Malaysia since the 1990's. Since then, studies have revealed that clinical clade D, Sporothrix schenckii sensu stricto, of a single clonal strain is the most common cause of this disease in Malaysia. The prevalence of a single clonal strain from a clinical clade was never before reported in Asia in a specific geographical niche. This raises the possibility of a process of purifying selection and subsequent clonal proliferation. While agricultural practices may serve as the selective pressure, direct causality has yet to be established...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28854184/exploring-virulence-and-immunogenicity-in-the-emerging-pathogen-sporothrix-brasiliensis
#13
Paula Portella Della Terra, Anderson Messias Rodrigues, Geisa Ferreira Fernandes, Angela Satie Nishikaku, Eva Burger, Zoilo Pires de Camargo
Sporotrichosis is a polymorphic chronic infection of humans and animals classically acquired after traumatic inoculation with soil and plant material contaminated with Sporothrix spp. propagules. An alternative and successful route of transmission is bites and scratches from diseased cats, through which Sporothrix yeasts are inoculated into mammalian tissue. The development of a murine model of subcutaneous sporotrichosis mimicking the alternative route of transmission is essential to understanding disease pathogenesis and the development of novel therapeutic strategies...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28846164/cutaneous-sporotrichosis-treated-with-methylene-blue-daylight-photodynamic-therapy
#14
Ana Julia García-Malinis, Ana Milagro Beamonte, Luis Torres Sopena, Oscar García-Callen, Pilar Puertolas-Villacampa, Yolanda Gilaberte
Sporotrichosis is an infection caused by the dimorphic fungus,Sporothrix schenckii. Acquisition typically occurs via cutaneous inoculation with development of a localized cutaneous and/or lymphocutaneous infection. aPDT (antimicrobial photodynamic therapy) is a process that generates reactive oxygen species (ROS) in presence of a photosensitizer, visible light and oxygen which destroys fungal and bacterial cells(1). Daylight PDT (DL-PDT) uses the visible spectrum of daylight (400-750nm) for the activation of the photosensitizer instead of an artificial light source...
August 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28833587/cutaneous-disseminated-sporotrichosis-clinical-experience-of-24-cases
#15
Alexandro Bonifaz, Andrés Tirado-Sánchez, Vanesa Paredes-Solís, Rodrigo Cepeda-Valdés, Gloria María González, Rogelio de J Treviño-Rangel, Leonel Fierro-Arias
Sporotrichosis is a subcutaneous mycosis, caused by complex Sporothrix schenckii, It is the most common implantation mycoses in worldwide. It is a polymorphic disease, cutaneous-lymphatic is the most frequent (75-90%).(1-3) We report our 25 years' experience (1990-2015) in cutaneous disseminated sporotrichosis (CDS). We conducted, an open, retrospective and observational study. This article is protected by copyright. All rights reserved.
August 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28774696/neglected-endemic-mycoses
#16
REVIEW
Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inability to work, physical deformities, and amputations...
November 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28706855/a-rare-case-of-disseminated-sporothrix-schenckii-with-bone-marrow-involvement-in-a-patient-with-idiopathic-cd4-lymphocytopenia
#17
Kruti J Yagnik, William Paul Skelton, Angela Olson, Cesar A Trillo, Jorge Lascano
Sporothrix schenckii is a pathogen with a predilection for dissemination in immunocompromised individuals, often with HIV. We report a case of disseminated sporotrichosis in an unfortunate 25 year old male (without HIV) who was originally treated for presumed pneumonia. The patient continued to worsen clinically and further work-up eventually revealed Sporothrix schenckii species with involvement of multiple organs including the skin, heart, lungs and bone marrow. Despite treatment with multiple antibacterials and antifungals, he ultimately passed away...
2017: IDCases
https://www.readbyqxmd.com/read/28702316/sporotrichosis-in-a-liver-transplant-patient-a-case-report-and-literature-review
#18
Renato Ferreira da Silva, Miguel Bonfitto, Francisco Inaldo Mendes da Silva Junior, Margarete Teresa Gottardo de Ameida, Rita de Cma da Silva
The liver transplant patient was admitted to the hospital with hyperemic, granulomatous, ulcerated lesion in the anterior compartment of the right lower limb with report of local trauma. The agent Sporothrix schenckii was isolated from biopsy of the lesion and lymph nodes of the right lower limb. In this case, the treatment was difficult because the patient has severe pulmonary hypertension and took the following drugs: warfarin, sildenafil, and tacrolimus. These medicines interact with the antifungal, which made it difficult...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28699881/chemical-composition-and-cytotoxicity-of-extracts-of-marjoram-and-rosemary-and-their-activity-against-sporothrix-brasiliensis
#19
Stefanie Bressan Waller, Isabel Martins Madrid, Jéssica Fernanda Hoffmann, Tony Picoli, Marlete Brum Cleff, Fábio Clasen Chaves, Renata Osório de Faria, Mário Carlos Araújo Meireles, João Roberto Braga de Mello
PURPOSE: Motivated by increasing reports of antifungal resistance in human and animal sporotrichosis, this study evaluated the chemical composition, cytotoxicity and anti-Sporothrix brasiliensis activity of extracts of marjoram (Origanum majorana) and rosemary (Rosmarinus officinalis). METHODOLOGY: Ten (INF10) and 60 min (INF60) infusions, a decoction and a hydroalcoholic extract (HAE, 70 %) were prepared from both plants (10 % w/v). The extract composition was analysed by liquid chromatography/mass spectrometry and the cytotoxicity was evaluated using a colorimetric assay in canine and feline kidney cells...
July 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28687406/comparative-efficacy-and-toxicity-of-two-vaccine-candidates-against-sporothrix-schenckii-using-either-montanide%C3%A2-pet-gel-a-or-aluminum-hydroxide-adjuvants-in-mice
#20
Deivys Leandro Portuondo, Alexander Batista-Duharte, Lucas Souza Ferreira, Cleverton Roberto de Andrade, Camila Quinello, Damiana Téllez-Martínez, Maria Luiza de Aguiar Loesch, Iracilda Zeppone Carlos
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous mycosis in Latin America, caused by different Sporothrix species. Currently, there is no effective vaccine available to prevent this disease. In this study, the efficacy and toxicity of the adjuvant Montanide™ Pet Gel A (PGA) formulated with S. schenckii cell wall proteins (ssCWP) was evaluated and compared with that of aluminum hydroxide (AH). Balb/c mice received two subcutaneous doses (1st and 14th days) of either the unadjuvanted or adjuvanted vaccine candidates...
July 4, 2017: Vaccine
keyword
keyword
120763
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"