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Interbody Bone Fusion

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https://www.readbyqxmd.com/read/28936559/posterior-column-reconstruction-improves-fusion-rates-at-the-level-of-osteotomy-in-three-column-posterior-based-osteotomies
#1
Stephen J Lewis, Chandan Mohanty, Aaron M Gazendam, So Kato, Sam G Keshen, Noah D Lewis, Sofia P Magana, David Perlmutter, Jennifer Cape
PURPOSE: To determine the incidence of pseudarthrosis at the osteotomy site after three-column spinal osteotomies (3-COs) with posterior column reconstruction. METHODS: 82 consecutive adult 3-COs (66 patients) with a minimum of 2-year follow-up were retrospectively reviewed. All cases underwent posterior 3-COs with two-rod constructs. The inferior facets of the proximal level were reduced to the superior facets of the distal level. If that was not possible, a structural piece of bone graft either from the local resection or a local rib was slotted in the posterior column defect to re-establish continual structural posterior bone across the lateral margins of the resection...
September 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28915307/the-use-of-bone-morphogenetic-protein-in-spinal-transforaminal-lumbar-interbody-fusion-our-experience
#2
Eduardo Colom-Beauchamp, David Beaton-Comulada, Julio A Rodriguez, José C Pérez-López, José Montañez-Huertas, Enrique Escobar-Medina, José Massanet-Vollrath
OBJECTIVE: Since its introduction and FDA approval, rhBMP-2 has been adopted by spine surgeons as a substitute for ICBG in numerous spinal fusion techniques. As broad clinical use increased, reports on potential complications associated with rhBMP-2 also increased. We provide our experience with TLIF using rhBMP-2 or ICBG in an entirely Hispanic population. METHODS: This was a 2-year retrospective study of 67 patients, with 26 in the rhBMP-2 group and 41 in the ICBG group, who underwent TLIF...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28886118/in-vivo-experimental-study-of-anterior-cervical-fusion-using-bioactive-polyetheretherketone-in-a-canine-model
#3
Takayoshi Shimizu, Shunsuke Fujibayashi, Seiji Yamaguchi, Bungo Otsuki, Yaichiro Okuzu, Tomiharu Matsushita, Tadashi Kokubo, Shuichi Matsuda
BACKGROUND: Polyetheretherketone (PEEK) is a widely accepted biomaterial, especially in the field of spinal surgery. However, PEEK is not able to directly integrate with bone tissue, due to its bioinertness. To overcome this drawback, various studies have described surface coating approaches aimed at increasing the bioactivity of PEEK surfaces. Among those, it has been shown that the recently developed sol-gel TiO2 coating could provide PEEK with the ability to bond with bone tissue in vivo without the use of a bone graft...
2017: PloS One
https://www.readbyqxmd.com/read/28875092/thoracolumbar-cortical-screw-placement-with-interbody-fusion-technique-and-considerations
#4
Michael Karsy, Michael R Jensen, Kyril Cole, Jian Guan, Andrea Brock, Chad Cole
A surge in interest in cortical bone trajectory (CBT), first described by Santoni in 2009, may be a result of its numerous advantages, including reduced surgical incision length and lateral dissection, limited disruption of the facet joints, and decreased blood loss. In addition, CBT offers improved screw pullout strength and the ability to perform hybrid constructs with pedicle screws using minimally invasive approaches. However, one of the main limitations of the technique involves the small screw size, which limits the potential for long-segment constructs...
July 2, 2017: Curēus
https://www.readbyqxmd.com/read/28874975/radiologic-and-clinical-courses-of-degenerative-lumbar-scoliosis-10%C3%A2-25%C3%A2-after-a-short-segment-fusion
#5
Kyu Yeol Lee, Min-Woo Kim, Chul Soon Im, Young Hoon Jung
STUDY DESIGN: Retrospective study. PURPOSE: We report the surgical outcomes of small degenerative lumbar scoliosis (DLS) patients treated by a short-segment fusion and followed for a minimum of 5 years. OVERVIEW OF LITERATURE: Several surgical options are available for the treatment of DLS, such as decompression only, decompression plus a short-segment fusion, or decompression with a long segment fusion. Few studies have evaluated the results of a short-segment fusion in patients with DLS over time...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28843115/double-level-isthmic-spondylolisthesis-treated-with-posterior-lumbar-interbody-fusion-a-review-of-32-cases
#6
DeYong Song, DeWei Song, KeHui Zhang, Zhong Chen, Feng Wang, TianHang Xuan
OBJECTIVE: The incidence of double-level isthmic spondylolisthesis is rare. The aim of this study is to evaluate the short-term functional and radiological outcomes of surgical treatment for double-level isthmic spondylolisthesis. PATIENTS AND METHODS: Between 2004 and 2014, thirty-two patients with double-level isthmic spondylolisthesis who underwent posterior lumbar interbody fusion (PLIF) with autogenous bone chips were reviewed retrospectively. The clinical outcomes were measured by VAS (Visual analog scale) and JOA(Japanese Orthopedic Association) score...
August 19, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28841904/a-comparison-of-radiographic-and-clinical-outcomes-of-anterior-lumbar-interbody-fusion-performed-with-either-a-cellular-bone-allograft-containing-multipotent-adult-progenitor-cells-or-recombinant-human-bone-morphogenetic-protein-2
#7
Daniel Dongwhan Lee, John Yongmin Kim
BACKGROUND: Both the map3 Cellular Allogeneic Bone Graft® and recombinant human bone morphogenetic protein 2 (rhBMP-2, Infuse®) were developed to provide an alternative to iliac crest autograft, thus eliminating the morbidity associated with its harvest. The recent literature concerning adverse events associated with the use of rhBMP-2, however, highlights the need for a safe and effective alternative. The multipotent adult progenitor cells (MAPC) found in map3 allograft may provide this alternative...
August 25, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28835868/anterior-cervical-discectomy-with-fusion-using-a-local-source-for-cancellous-autograft-a-biomechanical-analysis-of-vertebral-body-stability-in-an-osteopenic-bone-model
#8
Zakk Walterscheid, Conor O'Neill, Alex Ochs, Adrian D'Averso, Christopher Dew, Alyssa Huntington, Grace Ma, Caleb Behrend, Rafaella De Vita, Jonathan Carmouche
BACKGROUND: Anterior cervical discectomy with fusion is an effective treatment for patients having cervical radiculopathy and myelopathy. To reduce morbidity associated with autograft taken from the iliac crest without sacrificing high fusion rates, a novel technique that harvests bone from the vertebral body adjacent to the operative disc space has been proposed. The effects of square and round bone graft harvest techniques on the mechanical stability of the osteopenic donor vertebrae are unknown...
September 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28834885/morphological-analysis-of-interbody-fusion-following-posterior-lumbar-interbody-fusion-with-cages-using-computed-tomography
#9
Dong Kwang Seo, Myeong Jong Kim, Sung Woo Roh, Sang Ryong Jeon
Posterior lumbar interbody fusion (PLIF) using cages in conjunction with pedicle screw fixation is considered the gold standard for surgical treatment of degenerative lumbar spine disorders due to its biomechanical stability and high fusion rate. However, research regarding patterns of fusion in the interbody space during the early postoperative period is lacking.Sixty consecutive patients were recruited from May 2013 to June 2015. All patients underwent PLIF using 2 titanium cages filled with local bone chips from decompressed lamina and facet bone in conjunction with pedicle screw fixation...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28822825/comparison-of-transforaminal-lumbar-interbody-fusion-outcomes-in-patients-receiving-rhbmp-2-versus-autograft
#10
Taleef R Khan, Kalin R Pearce, Steven J McAnany, Colleen M Peters, Munish C Gupta, Lukas P Zebala
BACKGROUND CONTEXT: Recombinant human bone morphogenetic protein 2 (rhBMP-2) plays a pivotal role in complex spine surgery. Despite its limited approval, the off-label use of rhBMP-2 is prevalent, particularly in transforaminal lumbar interbody fusions (TLIF) PURPOSE: To determine the effectiveness and safety of rhBMP-2 use in TLIF procedures versus autograft. STUDY DESIGN: Retrospective Cohort Study PATIENT SAMPLE: Patients older than 18 years undergoing spine surgery for lumbar degenerative spine disease at a single academic institution...
August 16, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28817158/characteristics-and-efficacy-of-a-new-3-dimensional-printed-mesh-structure-titanium-alloy-spacer-for-posterior-lumbar-interbody-fusion
#11
Sung-Soo Chung, Kyung-Joon Lee, Yoo-Beom Kwon, Kyung-Chung Kang
This study evaluated the characteristics of a newly developed 3-dimensional printed mesh structure titanium spacer and its efficacy for posterior lumbar interbody fusion. Posterior lumbar interbody fusion with this spacer was performed at 53 segments (40 patients; mean age, 64 years; range, 51-73 years). Data were collected prospectively. Radiographic characteristics were analyzed with changes in interbody height, instability of the segments, formation of bone bridges around the implants, and pseudarthrosis, as determined by dynamic radiographs and postoperative computed tomography scans...
August 17, 2017: Orthopedics
https://www.readbyqxmd.com/read/28815162/clinical-application-of-ceramics-in-anterior-cervical-discectomy-and-fusion-a-review-and-update
#12
REVIEW
Shayan Abdollah Zadegan, Aidin Abedi, Seyed Behnam Jazayeri, Hirbod Nasiri Bonaki, Alexander R Vaccaro, Vafa Rahimi-Movaghar
STUDY DESIGN: Narrative review. OBJECTIVES: Anterior cervical discectomy and fusion (ACDF) is a reliable procedure, commonly used for cervical degenerative disc disease. For interbody fusions, autograft was the gold standard for decades; however, limited availability and donor site morbidities have led to a constant search for new materials. Clinically, it has been shown that calcium phosphate ceramics, including hydroxyapatite (HA) and tricalcium phosphate (TCP), are effective as osteoconductive materials and bone grafts...
June 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28808623/use-of-recombinant-human-bone-morphogenetic-protein-2-in-spine-surgery
#13
REVIEW
Marios Lykissas, Ioannis Gkiatas
Bone morphogenetic proteins are osteoinductive factors which have gained popularity in orthopaedic surgery and especially in spine surgery. The use of recombinant human bone morphogenetic protein-2 has been officially approved by the United States Food and Drug Administration only for single level anterior lumbar interbody fusion, nevertheless it is widely used by many surgeons with off-label indications. Despite advantages in bone formation, its use still remains a controversial issue and several complications have been described by authors who oppose their wide use...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28800665/fusion-rates-of-intervertebral-polyetheretherketone-and-titanium-cages-without-bone-grafting-in-posterior-interbody-lumbar-fusion-surgery-for-degenerative-lumbar-instability
#14
Christof von Wrangel, Ali Karakoyun, Kaye-Marie Buchholz, Olaf Süss, Theodoros Kombos, Johannes Woitzik, Peter Vajkoczy, Marcus Czabanka
No abstract text is available yet for this article.
August 11, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28797066/computationally-designed-lattices-with-tuned-properties-for-tissue-engineering-using-3d-printing
#15
Paul F Egan, Veronica C Gonella, Max Engensperger, Stephen J Ferguson, Kristina Shea
Tissue scaffolds provide structural support while facilitating tissue growth, but are challenging to design due to diverse property trade-offs. Here, a computational approach was developed for modeling scaffolds with lattice structures of eight different topologies and assessing properties relevant to bone tissue engineering applications. Evaluated properties include porosity, pore size, surface-volume ratio, elastic modulus, shear modulus, and permeability. Lattice topologies were generated by patterning beam-based unit cells, with design parameters for beam diameter and unit cell length...
2017: PloS One
https://www.readbyqxmd.com/read/28796062/usefulness-of-anterior-cervical-fusion-using-titanium-interbody-cage-for-treatment-of-cervical-degenerative-disease-with-preoperative-segmental-kyphosis
#16
Kunihiko Hosoi, Hitoshi Tonomura, Ryota Takatori, Masateru Nagae, Yasuo Mikami, Toru Osawa, Yuji Arai, Hiroyoshi Fujiwara, Toshikazu Kubo
Favorable bone fusion and clinical results have been reported for anterior cervical fusion (ACF) using titanium interbody cage (TIC). This method might induce postoperative subsidence and local kyphosis, but the relationship between radiological changes and preoperative local alignment is not known. The purpose of the present study is to investigate the impact of preoperative local alignment on the clinical and radiological outcomes of ACF using TIC.The study enrolled 36 patients (mean age 49.8 years) who underwent single-level ACF using TIC for cervical degenerative diseases...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28765799/fortifying-the-bone-implant-interface-part-1-an-in-vitro-evaluation-of-3d-printed-and-tps-porous-surfaces
#17
Regina F MacBarb, Derek P Lindsey, Chelsea S Bahney, Shane A Woods, Mark L Wolfe, Scott A Yerby
BACKGROUND: An aging society and concomitant rise in the incidence of impaired bone health have led to the need for advanced osteoconductive spinal implant surfaces that promote greater biological fixation (e.g. for interbody fusion cages, sacroiliac joint fusion implants, and artificial disc replacements). Additive manufacturing, i.e. 3D-printing, may improve bone integration by generating biomimetic spinal implant surfaces that mimic bone morphology. Such surfaces may foster an enhanced cellular response compared to traditional implant surfacing processes...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28751242/evaluation-of-a-peek-titanium-composite-interbody-spacer-in-an-ovine-lumbar-interbody-fusion-model-a-biomechanical-micro-computed-tomography-and-histologic-analyses
#18
Kirk C McGilvray, Erik I Waldorff, Jeremiah Easley, Howard B Seim, Nianli Zhang, Raymond J Linovitz, James T Ryaby, Christian M Puttlitz
BACKGROUND CONTEXT: The most commonly used materials used for interbody cages are titanium metal and polymer polyetheretherketone (PEEK). Both of these materials have demonstrated good biocompatibility. A major disadvantage associated with solid titanium cages is their radiopacity, limiting post-operative monitoring of spinal fusion via standard imaging modalities. However, PEEK is radiolucent, allowing for temporal assessment of the fusion mass by clinicians. On the other hand, PEEK is hydrophobic, which can limit bony in-growth...
July 24, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28746126/kirschner-wire-and-bone-cement-is-a-viable-alternative-to-reconstruction-of-large-iliac-bone-defects-after-strut-bone-graft-harvesting
#19
Shang-Won Yu, Chin-Hsien Wu, James Jih-Hsi Yeh, Cheng-Yo Yen, Ching-Hou Ma, Yuan-Kun Tu
STUDY DESIGN: A retrospective study. OBJECTIVE: To assess the safety and efficacy of iliac crest defect reconstruction using Kirschner wire (K-wire)/polymethylmethacrylate (PMMA) versus traditional autologous rib graft reconstruction. SUMMARY OF BACKGROUND DATA: The iliac crest has been the preferred donor site for strut bone graft for various spinal fusion surgeries. METHODS: Seventy-three patients (44 males and 29 females; average age: 57...
August 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28739516/endopelvic-approach-for-iliac-crest-bone-harvesting-technical-note
#20
S Le Pape, R Gauthe, L Du Pouget, O Gille, J-M Vital, M Ould-Slimane
BACKGROUND: The anterior approach to lumbar spine surgery has grown in popularity in the past few years; spinal fusion of the last two lumbar levels is often required. While there are alternatives to bone grafting available, including recombinant human bone morphogenetic protein 2 or bone substitutes, only cancellous autologous bone has all the required factors for bone growth. To avoid the use of bone substitutes, remote iliac crest bone harvesting remains the gold standard. However, this technique may lead to some unfavorable outcomes...
July 21, 2017: World Neurosurgery
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