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Interbody Bone Fusion

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https://www.readbyqxmd.com/read/27909656/outcomes-of-demineralized-bone-matrix-enriched-with-concentrated-bone-marrow-aspirate-in-lumbar-fusion
#1
Remi M Ajiboye, Mark A Eckardt, Jason T Hamamoto, Benjamin Plotkin, Michael D Daubs, Jeffrey C Wang
BACKGROUND: Multiple studies have demonstrated that a significant amount of variability exists in various demineralized bone matrix (DBM) formulations, which casts doubts on its reliability in consistently promoting fusion. Bone marrow aspirate (BMA) is a cellular based graft that contains mesenchymal stem cells (MSCs) and growth factors can confer osteogenic and osteoinductive potential to DBM. The goal of this study was to describe the outcome of DBM enriched with concentrated BMA in patients undergoing combined lumbar interbody and posterolateral fusion...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27906743/vertebral-body-hounsfield-units-are-associated-with-cage-subsidence-after-transforaminal-lumbar-interbody-fusion-with-unilateral-pedicle-screw-fixation
#2
Jie Mi, Kang Li, Xin Zhao, Chang-Qing Zhao, Hua Li, Jie Zhao
OBJECTIVE: To assess the association between Hounsfield units (HU) measurement and cage subsidence after lumbar interbody fusion. BACKGROUND: Transforaminal lumbar interbody fusion (TLIF) with unilateral fixation becomes a popular treatment modality for lumbar degenerative disease. Cage subsidence is a potentially devastating complication after lumbar interbody fusion with unilateral fixation. Recently, a new technique for assessing bone mineral density using HU values from computed tomography has been proposed...
November 30, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27899272/risk-factors-for-intervertebral-instability-assessed-by-temporal-evaluation-of-the-radiographs-and-reconstructed-computed-tomography-images-after-l5-s1-single-level-transforaminal-interbody-fusion-a-retrospective-study
#3
Yoshiomi Kobayashi, Yoshio Shinozaki, Yohei Takahashi, Hironari Takaishi, Jun Ogawa
Intervertebral instability risks following L5-S1 transforaminal lumbar interbody fusion (TLIF) and causes of bony bridge formation on computed tomography (CT) remain largely unknown. We evaluated the temporal changes on plain radiographs and reconstructed CT images from 178 patients who had undergone single-level L5-S1 TLIF between February 2011 and February 2015. We statistically analyzed temporal changes the L5-S1 angle on radiographs and intervertebral stability (IVS) at the last observation. Bony bridge formation between the L5-S1 vertebral bodies and the titanium cage subsidence were analyzed by using reconstructed CT...
October 28, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27853658/analysis-of-recombinant-human-bone-morphogenetic-protein-2-use-in-the-treatment-of-lumbar-degenerative-spondylolisthesis
#4
Qingqiang Yao, Jeremiah R Cohen, Zorica Buser, Jong-Beom Park, Darrel S Brodke, Hans-Joerg Meisel, Jim A Youssef, Jeffrey C Wang, S Tim Yoon
Study Design Retrospective database review. Objective To identify trends of the recombinant human bone morphogenetic protein-2 (rhBMP-2) use in the treatment of lumbar degenerative spondylolisthesis (LDS). Methods PearlDiver Patient Record Database was used to identify patients who underwent lumbar fusion for LDS between 2005 and 2011. The distribution of bone morphogenetic protein use rate (BR) in various surgical procedures was recorded. Patient numbers, reoperation numbers, BR, and per year BR (PYBR) were stratified by geographic region, gender, and age...
December 2016: Global Spine Journal
https://www.readbyqxmd.com/read/27843679/high-neurological-complication-rates-for-extreme-lateral-lumbar-interbody-fusion-and-related-techniques-a-review-of-safety-concerns
#5
Nancy E Epstein
BACKGROUND: There are frequent reports of lumbosacral plexus and other neurological injuries occurring with extreme lateral interbody fusions (XLIF) and other related lateral lumbar techniques. METHODS: This review focuses on the new neurological deficits (e.g. lumbosacral plexus, root injuries) that occur following minimally invasive surgery (MIS) XLIF and other related lateral lumbar techniques. RESULTS: A review of multiple articles revealed the following ranges of new postoperative neurological complications for XLIF procedures: plexus injuries 13...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27836500/ex-vivo-loading-of-trussed-implants-for-spine-fusion-induces-heterogeneous-strains-consistent-with-homeostatic-bone-mechanobiology
#6
Jason P Caffrey, Esther Cory, Van W Wong, Koichi Masuda, Albert C Chen, Jessee P Hunt, Timothy M Ganey, Robert L Sah
A truss structure was recently introduced as an interbody fusion cage. As a truss system, some of the connected elements may be in a state of compression and others in tension. This study aimed to quantify both the mean and variance of strut strains in such an implant when loaded in a simulated fusion condition with vertebral body or contoured plastic loading platens ex vivo. Cages were each instrumented with 78 fiducial spheres, loaded between platens (vertebral body or contoured plastic), imaged using high resolution micro-CT, and analyzed for deformation and strain of each of the 221 struts...
November 3, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27831994/pseudarthrosis-repair-using-autologous-cultured-osteoblasts-in-complex-type-1-neurofibromatosis-spinal-deformity-a-case-report-and-review-of-the-literature
#7
Young-Hoon Kim, Genriech N Reoyan, Kee-Yong Ha, Chul-Kyu Kim
STUDY DESIGN: A case report and literature review. OBJECTIVE: To report a late dislocation of the vertebra caused by progressive dural ectasia combined with type-1 neurofibromatosis (NF-1) and the clinical results of pseudarthrosis repairs using autologous cultured osteoblasts. SUMMARY OF BACKGROUND DATA: NF-1 is a well-known genetic disorder that is commonly characterized by spinal deformities including kyphoscoliosis. Late dislocation of the vertebra resulting from progressive dural ectasia after surgical correction of NF-1 scoliosis is a very rare occurrence, and pseudarthrosis frequently develops after surgical intervention for this complex spinal deformity...
November 15, 2016: Spine
https://www.readbyqxmd.com/read/27802255/diagnosing-the-undiagnosed-osteoporosis-in-patients-undergoing-lumbar-fusion
#8
Scott C Wagner, Peter M Formby, Melvin D Helgeson, Daniel G Kang
STUDY DESIGN: Retrospective analysis. OBJECTIVE: The aim of the study was to report the incidence of undiagnosed osteoporosis in patients undergoing lumbar spine fusion using computed tomography (CT) Hounsfield units (HU). SUMMARY OF BACKGROUND DATA: We used a recent technique utilizing HU to estimate bone mineral density (BMD) of the lumbar spine and hypothesized that this technique would reveal a high percentage of undiagnosed osteoporotic patients undergoing transforaminal lumbar interbody fusion (TLIF)...
November 1, 2016: Spine
https://www.readbyqxmd.com/read/27792109/comparison-of-three-surgical-approaches-for-thoracic-spinal-tuberculosis-in-adult-minimum-5-year-follow-up
#9
Long-Jie Wang, Hong-Qi Zhang, Ming-Xing Tang, Qi-le Gao, Zhen-Hai Zhou, Xin-Hua Yin
STUDY DESIGN: Retrospective. OBJECTIVE: To assess the minimum 5-year follow-up outcomes of the surgical management of adults with thoracic tuberculosis by comparing posterior only (PO), anterior only (AO), and combined posterior and anterior (AP) surgical approaches. SUMMARY OF BACKGROUND DATA: Surgeons use multiple methods to treat spinal tuberculosis, including an anterior, posterior, and combined anterior and posterior approach. However, there are few reports comparing the mid- and long-term outcomes of these surgical methods...
October 25, 2016: Spine
https://www.readbyqxmd.com/read/27790319/predisposing-factors-for-intraoperative-endplate-injury-of-extreme-lateral-interbody-fusion
#10
Kotaro Satake, Tokumi Kanemura, Hidetoshi Yamaguchi, Naoki Segi, Jun Ouchida
STUDY DESIGN: Retrospective study. PURPOSE: To compare intraoperative endplate injury cases and no injury cases in consecutive series and to identify predisposing factors for intraoperative endplate injury. OVERVIEW OF LITERATURE: Unintended endplate violation and subsequent cage subsidence is an intraoperative complication of extreme lateral interbody fusion (XLIF). It is still unknown whether it is derived from inexperienced surgical technique or patients' inherent problems...
October 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27770186/fusion-rate-and-clinical-outcome-in-anterior-lumbar-interbody-fusion-with-beta-tricalcium-phosphate-and-bone-marrow-aspirate-as-a-bone-graft-substitute-a-prospective-clinical-study-in-fifty-patients
#11
Ricarda Lechner, David Putzer, Michael Liebensteiner, Christian Bach, Martin Thaler
PURPOSE: Bone graft substitutes have been successfully used in posterolateral lumbar fusion, anterior cervical fusion and animal studies. This study has been conducted to assess the safety and efficacy of β-tricalcium phosphate (β-TCP) in instrumented anterior lumbar interbody fusion (ALIF) procedure. METHODS: In a prospective clinical study, ALIF cages were prefilled with β-TCP and additionally fixated with posterior pedicle screw. Computed tomography (CT) and X-rays were performed one year after surgery...
October 21, 2016: International Orthopaedics
https://www.readbyqxmd.com/read/27760661/-clinical-results-of-the-patients-with-severe-kyphosis-and-paraplegia-in-different-spine-segment-due-to-tuberculosis-of-thoracic-and-lumbar-treated-by-one-stage-posterior-surgical-procedure-to-debriment-of-lesion-bone-fusion-with-internal-fixation-by-pedicle
#12
J Tayierjiang, N Waresijiang, H Wang
Objective: To evaluate the clinical results of the patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar had been treated by one stage posterior surgical procedure to debriment of lesion and titian mesh bone fusion with internal fixation by pedicle screw system. Method: From May 2008 to March 2014, there were total 30 patients with severe kyphosis and paraplegia in different spine segment due to tuberculosis of thoracic and lumbar in Department of Orthopaedics, the People's Hospital of Xinjiang Uygur Autonoumy Region...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27756345/the-new-zero-p-implant-can-effectively-reduce-the-risk-of-postoperative-dysphagia-and-complications-compared-with-the-traditional-anterior-cage-and-plate-a-systematic-review-and-meta-analysis
#13
Mengchen Yin, Junming Ma, Quan Huang, Ye Xia, Qixing Shen, Chenglong Zhao, Jun Tao, Ni Chen, Zhingxing Yu, Jie Ye, Wen Mo, Jianru Xiao
BACKGROUND: The low-profile angle-stable spacer Zero-P is a new kind of cervical fusion system that is claimed to limit the potential drawbacks and complications. The purpose of this meta-analysis was to compare the clinical and radiological results of the new Zero-P implant with those of the traditional anterior cage and plate in the treatment of symptomatic cervical spondylosis, and provides clinicians with evidence on which to base their clinical decision making. METHODS: The following electronic databases were searched: PMedline, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, Evidence Based Medicine Reviews, VIP, and CNKI...
October 18, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27720376/anterior-cervical-interbody-fusion-using-polyetheretherketone-cage-filled-with-synthetic-bone-graft-in-acute-cervical-spine-injury
#14
L Hattou, X Morandi, J Lefebvre, P-J Le Reste, L Riffaud, P-L Hénaux
PURPOSE: The aim of this study was to assess the interbody fusion rate for patients treated by anterior cervical interbody fusion (ACIF) using polyetheretherketone (PEEK) cages filled with synthetic bone graft in acute cervical spine injury. MATERIALS AND METHODS: Twenty-nine patients (mean age: 49 years) with monosegmental instability due to cervical spine injury were followed. We assessed the rate of and time to interbody fusion at 1-year follow-up. In case of secondary displacement, we analysed its causes and surgical management...
October 5, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27683681/surgery-for-spinal-tuberculosis-a-multi-center-experience-of-582-cases
#15
Md Shah Alam, Kevin Phan, Rezaul Karim, Sharif Ahmed Jonayed, Hasan Khalid Md Munir, Shubhendu Chakraborty, Tashfique Alam
BACKGROUND: Tuberculosis (TB) of the spine is a common site of osseous TB, accounting for 50%-60% of cases. Spinal TB still occurs in both developed and developing countries. The diagnosis of spinal TB is difficult and it commonly presents at an advanced stage. Delays in establishing diagnosis and management result in complications such as spinal cord compression and spinal deformity. METHODS: A total of 582 patients with TB of the cervical, thoracic and lumbar spine with moderate to severe cord compression were studied...
December 2015: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27627709/advances-in-spinal-interbody-cages
#16
REVIEW
Sukrit Jain, Adam E M Eltorai, Roy Ruttiman, Alan H Daniels
Since the late 1980s, spinal interbody cages (ICs) have been used to aid bone fusion in a variety of spinal disorders. Utilized to restore intervertebral height, enable bone graft containment for arthrodesis, and restore anterior column biomechanical stability, ICs have since evolved to become a highly successful means of achieving fusion, being associated with less postoperative pain, shorter hospital stay, fewer complications and higher rates of fusion when than bone graft only spinal fusion. IC design and materials have changed considerably over the past two decades...
August 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/27627708/evolution-of-design-of-interbody-cages-for-anterior-lumbar-interbody-fusion
#17
REVIEW
Kevin Phan, Ralph J Mobbs
Anterior lumbar interbody fusion (ALIF) is one of the surgical procedures for the relief of chronic back pain, radiculopathy and neurogenic claudication in patients with degenerative lumbar spine disease that is refractory to conservative therapy, low-grade spondylolisthesis and pseudo arthrosis. Over the past half century, both the surgical techniques and instrumentation required for ALIF have changed significantly. In particular, the designs of ALIF cage and the materials used have evolved dramatically, the common goal being to improve fusion rates and optimize clinical outcomes...
August 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/27626889/development-of-an-integrated-cad-fea-system-for-patient-specific-design-of-spinal-cages
#18
Mingzheng Zhang, Fang Pu, Liqiang Xu, Linlin Zhang, Hang Liang, Deyu Li, Yu Wang, Yubo Fan
Spinal cages are used to create a suitable mechanical environment for interbody fusion in cases of degenerative spinal instability. Due to individual variations in bone structures and pathological conditions, patient-specific cages can provide optimal biomechanical conditions for fusion, strengthening patient recovery. Finite element analysis (FEA) is a valuable tool in the biomechanical evaluation of patient-specific cage designs, but the time- and labor-intensive process of modeling limits its clinical application...
September 14, 2016: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/27623301/cross-sectional-area-of-the-lumbar-spine-trunk-muscle-and-posterior-lumbar-interbody-fusion-rate-a-retrospective-study
#19
Man Kyu Choi, Sung Bum Kim, Chang Kyu Park, Hridayesh P Malla, Sung Min Kim
STUDY DESIGN: A retrospective study. OBJECTIVE: To investigate the relationship between trunk muscle cross-sectional area (MCSA) and fusion rate after posterior lumbar interbody fusion using pedicle screw fixation (PLIF-PSF). SUMMARY OF BACKGROUND DATA: Although trunk muscles of the lumbar spine contribute to spinal stability and alignment, effect of trunk muscles on spinal fusion rate and time to fusion is unclear. METHODS: A total of 192 adult patients with degenerative lumbar disease who underwent PLIF-PSF at L3-L4 or L4-L5 were included...
September 10, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27623299/radiographic-and-clinical-outcome-of-silicate-substituted-calcium-phosphate-si-cap-ceramic-bone-graft-in-spinal-fusion-procedures
#20
Marjan Alimi, Rodrigo Navarro-Ramirez, Karishma Parikh, Innocent Njoku, Christoph P Hofstetter, Apostolos J Tsiouris, Roger Härtl
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To evaluate the radiographic and clinical outcome of silicate-substituted calcium phosphate (Si-CaP), utilized as a graft substance in spinal fusion procedures. SUMMARY OF BACKGROUND DATA: Specific properties of Si-CaP provide the graft with negative surface charge that can result in a positive effect on the osteoblast activity and neovascularization of the bone. METHODS: This study included those patients who underwent spinal fusion procedures between 2007 and 2011 in which Si-CaP was used as the only bone graft substance...
September 10, 2016: Clinical Spine Surgery
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