keyword
MENU ▼
Read by QxMD icon Read
search

enterococcus vre

keyword
https://www.readbyqxmd.com/read/29028276/enhancing-antibiotic-stewardship-by-tackling-spurious-penicillin-allergy
#1
Mamidipudi Thirumala Krishna, Aarnoud P Huissoon, Mark Li, Alex Richter, Devadas Ganesh Pillay, Dhinakaran Sambanthan, Sumanth C Raman, Shuaib Nasser, Siraj A Misbah
Approximately 90-99% of patients with a label of penicillin allergy (PenA) are not allergic when comprehensively investigated. An inaccurate label of PenA has major public health implications - longer hospital stay, more frequent hospital admissions, greater use of fluoroquinolones, glycopeptides, cephalosporins and other expensive antibiotics resulting in significantly higher costs to the health service and predisposing to Clostridium difficile, meticillin-resistant Staphylococcus aureus infections and vancomycin resistant enterococcus...
October 13, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29023515/a-novel-bacteriocin-from-enterococcus-faecalis-478-exhibits-a-potent-activity-against-vancomycin-resistant-enterococci
#2
Uraporn Phumisantiphong, Kanokrat Siripanichgon, Onrapak Reamtong, Pornphan Diraphat
The emergence of multidrug-resistant enterococci (MDRE) and particularly vancomycin-resistant enterococci (VRE) is considered a serious health problem worldwide, causing the need for new antimicrobials. The aim of this study was to discover and characterize bacteriocin against clinical isolates of MDRE and VRE. Over 10,000 bacterial isolates from water, environment and clinical samples were screened. E. faecalis strain 478 isolated from human feces produced the highest antibacterial activity against several MDRE and VRE strains...
2017: PloS One
https://www.readbyqxmd.com/read/29023124/synthesis-and-antimicrobial-evaluation-of-fire-ant-venom-alkaloid-based-2-methyl-6-alkyl-%C3%AE-1-6-piperideines
#3
Yujie Yan, Yu An, Xiaozhong Wang, Yingqi Chen, Melissa R Jacob, Babu L Tekwani, Liyan Dai, Xing-Cong Li
The first synthesis of 2-methyl-6-pentadecyl-Δ(1,6)-piperideine (1), a major alkaloid of the piperideine chemotype in fire ant venoms, and its analogues, 2-methyl-6-tetradecyl-Δ(1,6)-piperideine (2) and 2-methyl-6-hexadecyl-Δ(1,6)-piperideine (3), was achieved by a facile synthetic method starting with glutaric acid (4) and urea (5). Compound 1 showed in vitro antifungal activity against Cryptococcus neoformans and Candida albicans with IC50 values of 6.6 and 12.4 μg/mL, respectively, and antibacterial activity against vancomycin-resistant Enterococcus faecium with an IC50 value of 19...
October 12, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/29017424/development-of-a-statewide-antibiogram-to-assess-regional-trends-in-antibiotic-resistant-eskape-organisms
#4
Anthony J Guarascio, Laura M Brickett, Timothy J Porter, Nancy D Lee, Erin E Gorse, Jordan R Covvey
BACKGROUND: Hospitals and other facilities utilize antibiograms as tools for optimal antibiotic selection. Currently, no measures compare broad trends on the regional level, despite interest for more comprehensive data, particularly for antibiotic-resistant ESKAPE organisms. OBJECTIVE: To collect and compare regional health-care facility antibiogram data for ESKAPE organisms to form a cumulative antibiogram. METHODS: Health-care facilities were identified using the publicly accessible Pennsylvania Department of Health web site...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29016585/isolation-of-multidrug-resistant-bacteria-from-patients-medical-charts
#5
Roshan Thapa, Narayan Dutt Pant, Uday Narayan Yadav, Eliza Thapa, Anjana Singh, Bharat Mani Pokhrel, Upendra Devkota
BACKGROUND: Patient's medical charts in hospitals are potentially contaminated by pathogenic bacteria and might act as vehicles for transmission of bacterial infections.This study was aimed to determine the rate of contamination of medical charts by multidrug resistant bacteria. METHODS: Sampling of total 250 patient's medical charts from different wards was done with the help of cotton swabs soaked in sterile normal saline. The swabs thus collected were cultured using standard microbiological procedures...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28989875/bacteriological-profile-of-diabetic-foot-ulcer-with-special-reference-to-drug-resistant-strains-in-a-tertiary-care-center-in-north-east-india
#6
Sudhir K Jain, Rashmisnata Barman
AIM: This study was carried out to determine the bacteriological profile of infected diabetic foot ulcers (DFUs) and the antibiotic resistance pattern from the isolates. An attempt was made to suggest an empiric antibiotic regimen to treat such patients. MATERIALS AND METHODS: Tissue samples were collected from 150 patients between February 2015 and January 2016 with DFUs under aseptic precautions and they were processed as per the Clinical and Laboratory Standards Institute guidelines...
September 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28989519/outbreak-of-vancomycin-resistant-enterococcus-on-a-haematology-ward-management-and-control
#7
Diego García Martínez de Artola, Beatriz Castro, María José Ramos, Zaida Díaz Cuevas, Sunil Lakhwani, María Lecuona
Vancomycin-resistant enterococci (VRE) infections and outbreaks are still infrequent in Spain. A six-month outbreak, which took place in a haematology ward, its control and management are described in this study. A total of 22 patients were colonised and two bloodstream infections occurred during this period. Even though there were two waves of new colonised patients, a multidisciplinary approach, quick interventions and enhanced infection control policies were required in order to control this outbreak.
May 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/28983096/chlorinated-emodin-as-a-natural-antibacterial-agent-against-drug-resistant-bacteria-through-dual-influence-on-bacterial-cell-membranes-and-dna
#8
Feixia Duan, Guang Xin, Hai Niu, Wen Huang
The rise in infections caused by drug-resistant pathogens and a lack of effective medicines requires the discovery of new antibacterial agents. Naturally chlorinated emodin 1,3,8-trihydroxy-4-chloro-6-methyl-anthraquinone (CE) from fungi and lichens was found to markedly inhibit the growth of Gram-positive bacteria, especially common drug-resistant bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VRE). CE was confirmed to cause significant potassium leakage, cell membrane depolarization and damage to the selective permeability of cell membranes in bacterial cells, resulting in bacterial cell death...
October 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28961986/novel-multiresistance-cfr-plasmids-in-linezolid-resistant-methicillin-resistant-staphylococcus-epidermidis-and-vancomycin-resistant-enterococcus-faecium-vre-from-a-hospital-outbreak-co-location-of-cfr-and-optra-in-vre
#9
Alexandros Lazaris, David C Coleman, Angela M Kearns, Bruno Pichon, Peter M Kinnevey, Megan R Earls, Breida Boyle, Brian O'Connell, Gráinne I Brennan, Anna C Shore
Background: Linezolid is often the drug of last resort to treat infections caused by Gram-positive cocci. Linezolid resistance can be mutational (23S rRNA or L-protein) or, less commonly, acquired [predominantly cfr , conferring resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins and streptogramin A compounds (PhLOPS A ) or optrA , encoding oxazolidinone and phenicol resistance]. Objectives: To investigate the clonality and genetic basis of linezolid resistance in 13 linezolid-resistant (LZDR) methicillin-resistant Staphylococcus epidermidis (MRSE) isolates recovered during a 2013/14 outbreak in an ICU in an Irish hospital and an LZDR vancomycin-resistant Enterococcus faecium (VRE) isolate from an LZDR-MRSE-positive patient...
August 28, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28960264/clinical-impact-of-colonization-with-multidrug-resistant-organisms-on-outcome-after-allogeneic-stem-cell-transplantation-in-patients-with-acute-myeloid-leukemia
#10
Sebastian Scheich, Sarah Lindner, Rosalie Koenig, Claudia Reinheimer, Thomas A Wichelhaus, Michael Hogardt, Silke Besier, Volkhard A J Kempf, Johanna Kessel, Hans Martin, Anne C Wilke, Hubert Serve, Gesine Bug, Björn Steffen
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option for patients with acute myeloid leukemia (AML). During transplantation, patients undergo a period of severe neutropenia, which puts them at high risk for infectious complications. However, the impact of patient colonization with multidrug-resistant organisms (MDRO) on overall survival remains unclear. METHODS: In this retrospective, single-center study, the authors analyzed data from 264 patients with AML who underwent a first allo-HSCT between January 2006 and March 2016 at their institution...
September 28, 2017: Cancer
https://www.readbyqxmd.com/read/28951333/complications-during-the-treatment-of-diabetic-foot-osteomyelitis
#11
Suzanne A V van Asten, Moez Mithani, Edgar J G Peters, Javier La Fontaine, Paul J Kim, Lawrence A Lavery
AIM: To identify complications of medical treatment in patients with diabetic foot osteomyelitis (DFO). METHODS: We reviewed 143 records of consecutive patients admitted with DFO, confirmed by bone histopathology or culture. Complications monitored included acute kidney injuries (AKI), development of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), gastrointestinal complications, and venous catheter related complications during a 12 months follow-up period...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28951015/effectiveness-of-an-ultraviolet-c-disinfection-system-for-reduction-of-healthcare-associated-pathogens
#12
Jui-Hsuan Yang, Un-In Wu, Huei-Min Tai, Wang-Huei Sheng
BACKGROUND: Healthcare-associated infections caused by multidrug-resistant (MDR) pathogens are significantly associated with increased mortality and morbidity. Environmental cleaning can reduce transmission of these pathogens but is often inadequate. Adjunctive methods are warranted to enhance the effectiveness of disinfection particularly in hospital settings where healthcare-associated infections are of major concern. METHODS: We conducted a study to examine the effectiveness of a mobile, automatic device, Hyper Light Disinfection Robot (model: Hyper Light P3), which utilized ultraviolet-C (UV-C) to kill MDR-Pseudomonas aeruginosa, MDR- Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), Mycobacterium abscessus and Aspergillus fumigatus...
September 18, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28950170/facile-synthesis-structure-biocompatibility-and-antimicrobial-property-of-gold-nanoparticle-composites-from-cellulose-and-keratin
#13
Chieu D Tran, Franja Prosenc, Mladen Franko
A novel, one-pot method was developed to synthesize gold nanoparticle composite from cellulose (CEL), wool keratin (KER) and chloroauric acid. Two ionic liquids, butylmethylimmidazolium chloride and ethylmethylimmidazolium bis(trifluoromethylsulfonyl)imide were used to dissolve CEL, KER and HAuCl4. X-ray diffraction and X-ray photoelectron results show that Au(3+) was completely reduced to Au(0)NPs with size of (5.5±1) nm directly in the composite with NaBH4. Spectroscopy and imaging results indicate that CEL and KER remained chemically intact and were homogeneously distributed in the composites with Au(0)NPs...
September 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28945343/in-vivo-anti-biofilm-and-anti-bacterial-non-leachable-coating-thermally-polymerized-on-cylindrical-catheter
#14
Chao Zhou, Yang Wu, Kishore Reddy Venkata Thappeta, Jo Thy Lachumy Subramanian, Dicky Pranantyo, En-Tang Kang, Hongwei Duan, Kimberly Kline, Mary B Chan-Park
Catheters are indispensable tools of modern medicine but catheter-associated infection is a significant clinical problem, even when stringent sterile protocols are observed. When the bacteria colonize catheter surfaces, they tend to form biofilms making them hard to treat with conventional antibiotics. Hence, there is a great need for inherently antifouling and anti-bacterial catheters that prevent bacterial colonization. This paper reports the preparation of non-leachable anti-biofilm and anti-bacterial cationic film coatings directly polymerized from actual tubular silicone catheter surfaces via the technique of supplemental activator and reducing agent surface initiated atom transfer radical polymerization (SARA SI-ATRP)...
September 25, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28941790/resistance-mechanism-and-clinical-characteristics-of-linezolid-resistant-enterococcus-faecium-a-single-center-study-in-korea
#15
Sun Young Cho, Hye Mee Kim, Doo Ryeon Chung, So Hyun Kim, Hee Jae Huh, Cheol-In Kang, Kyong Ran Peck, Nam Yong Lee, Jae-Hoon Song
OBJECTIVES: This study aimed to determine the prevalence of linezolid-resistant vancomycin-resistant Enterococcus (LR-VRE) and investigate the mechanisms for linezolid resistance with clinical and microbiological characterization. METHODS: All vancomycin-resistant Enterococcus faecium (VREF) isolates from blood and rectal swab cultures during 2012-2015 were tested for linezolid resistance. LR-VREF isolates were tested for antimicrobial susceptibility, genes for glycopeptide resistance, and virulence genes...
September 20, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28935609/novel-insights-into-the-vancomycin-resistant-enterococcus-faecalis-v583-alkylhydroperoxide-reductase-subunit-f
#16
Yew Kwang Toh, Asha Manikkoth Balakrishna, Malathy Sony Subramanian Manimekalai, Boon Bin Chionh, Ramya Ramaswamy Chettiyan Seetharaman, Frank Eisenhaber, Birgit Eisenhaber, Gerhard Grüber
The ability of the vancomycin-resistant Enterococcus faecalis (V583) to restore redox homeostasis via antioxidant defense mechanism is of importance, and knowledge into this defense is essential to understand its antibiotic-resistance and survival in hosts. The flavoprotein disulfide reductase AhpR, composed of the subunits AhpC and AhpF, represents one such vital part. Circular permutation was found to be a feature of the AhpF protein family. E. faecalis (V583) AhpF (EfAhpF) appears to be a representative of a minor subclass of this family, the typically N-terminal two-fold thioredoxin-like domain (NTD_N/C) is located at the C-terminus, whereas the pyridine nucleotide-disulfide oxidoreductase domain is encoded in the N-terminal part of its sequence...
September 18, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28916373/methods-for-computational-disease-surveillance-in-infection-prevention-and-control-statistical-process-control-versus-twitter-s-anomaly-and-breakout-detection-algorithms
#17
Timothy L Wiemken, Stephen P Furmanek, William A Mattingly, Marc-Oliver Wright, Annuradha K Persaud, Brian E Guinn, Ruth M Carrico, Forest W Arnold, Julio A Ramirez
BACKGROUND: Although not all health care-associated infections (HAIs) are preventable, reducing HAIs through targeted intervention is key to a successful infection prevention program. To identify areas in need of targeted intervention, robust statistical methods must be used when analyzing surveillance data. The objective of this study was to compare and contrast statistical process control (SPC) charts with Twitter's anomaly and breakout detection algorithms. METHODS: SPC and anomaly/breakout detection (ABD) charts were created for vancomycin-resistant Enterococcus, Acinetobacter baumannii, catheter-associated urinary tract infection, and central line-associated bloodstream infection data...
September 12, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28894187/small-rnas-in-vancomycin-resistant-enterococcus-faecium-involved-in-daptomycin-response-and-resistance
#18
Clara Sinel, Yoann Augagneur, Mohamed Sassi, Julie Bronsard, Margherita Cacaci, François Guérin, Maurizio Sanguinetti, Pierrick Meignen, Vincent Cattoir, Brice Felden
Vancomycin-resistant Enterococcus faecium is a leading cause of hospital-acquired infections and outbreaks. Regulatory RNAs (sRNAs) are major players in adaptive responses, including antibiotic resistance. They were extensively studied in gram-negative bacteria, but less information is available for gram-positive pathogens. No sRNAs are described in E. faecium. We sought to identify a set of sRNAs expressed in vancomycin-resistant E. faecium Aus0004 strain to assess their roles in daptomycin response and resistance...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28890862/where-is-the-difference-between-an-epidemic-and-a-high-endemic-level-with-respect-to-nosocomial-infection-control-measures-an-analysis-based-on-the-example-of-vancomycin-resistant-enterococcus-faecium-in-hematology-and-oncology-departments
#19
REVIEW
Nikos Ulrich, Petra Gastmeier
Some infection control recommendations distinguish epidemic and endemic levels for infection control. However, it is often difficult to separate long lasting outbreaks from high endemic levels and it remains open, if this distinction is really useful. Aim: To compare infection control measures in endemic and epidemic outbreaks. Methods: The example of vancomycin-resistant Enterococcus faecium outbreaks in haematology or oncology departments was used to analyse differences in infection control measures between outbreaks and high endemic levels...
2017: GMS Hygiene and Infection Control
https://www.readbyqxmd.com/read/28882784/high-prevalence-of-diverse-vancomycin-resistance-enterococcus-faecium-isolates-in-clinical-and-environmental-sources-in-icu-wards-in-southwest-of-iran
#20
Maniya Arshadi, Masoumeh Douraghi, Leili Shokoohizadeh, Seyed Mojtaba Moosavian, Mohammad Reza Pourmand
This study aimed at determining the prevalence, antibiotic resistance patterns, and genetic linkage of Vancomycin Resistant Enterococcus faecium (VREfm) from different sources in the southwest of Iran. A total of 51 VREfm isolates were obtained and subjected to antibiotic susceptibility testing, carriage of virulence genes, and pulsed-field gel electrophoresis (PFGE) method. All the VRE isolates exhibited a high level of resistance to teicoplanin, ampicillin, erythromycin, ciprofloxacin, and gentamicin, also carried the vanA gene...
October 2017: Microbial Pathogenesis
keyword
keyword
120730
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"