keyword
MENU ▼
Read by QxMD icon Read
search

Lacrimal gland

keyword
https://www.readbyqxmd.com/read/29342030/mesenchymal-chondrosarcoma-of-the-lacrimal-gland
#1
Hayyam Kiratli, Yağmur Deniz, Berrin Büyükeren, Gökhan Gedikoğlu
A 23-year-old woman presented with right-sided painless proptosis that developed in 12 months. MRI studies demonstrated a well-delineated tumorous enlargement of the right lacrimal gland with homogenous signal intensity and compressing the globe. The tumor was removed totally and in 1 piece with the tentative diagnosis of a pleomorphic adenoma. Pathologic examination revealed biphasic neoplastic elements, which were composed of the cartilaginous matrix and small round cell component. Immunohistopathological examination showed positive CD99 staining and negative reaction to S100, panCK, and CD15...
January 16, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29329570/exophthalmos-in-a-young-woman-with-no-graves-disease-a-case-report-of-igg4-related-orbitopathy
#2
Annamaria Erdei, Zita Steiber, Csaba Molnar, Ervin Berenyi, Endre V Nagy
BACKGROUND: Immunoglobulin G4-related disease (IgG4-rd) is characterized by lymphoplasmacytic infiltration and tissue fibrosis. Orbital manifestations of IgG4-rd may include unilateral or bilateral proptosis, cicatricial extraocular muscle myopathy, orbital inflammation and pain which may mimic ophthalmic Graves' disease. CASE PRESENTATION: A 25-year-old woman has been referred to the endocrinology clinic, 4 months after delivery, with suspected Graves' orbitopathy...
January 12, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29319640/orbital-extranodal-marginal-zone-lymphoma-following-radiotherapy-a-report-of-2-cases
#3
Zujaja Tauqeer, Frederick A Jakobiec, Suzanne K Freitag, Michael K Yoon, Natalie Wolkow
PURPOSE: To present 2 patients in whom orbital radiation preceded the development of periorbital extranodal marginal zone lymphoma by more than a decade and to investigate the likelihood of this representing irradiation-induced malignancy. METHODS: Retrospective chart review and histopathologic study with immunohistochemistry of 2 cases. RESULTS: The first patient was a 58-year-old woman who developed an orbital mass within the vicinity of the lateral rectus muscle 17 years after external beam proton radiation therapy for an inferotemporal choroidal melanoma...
January 9, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29318025/feline-dry-eye-syndrome-of-presumed-neurogenic-origin-a-case-report
#4
Lionel Sebbag, Patricia A Pesavento, Sebastian E Carrasco, Christopher M Reilly, David J Maggs
Case summary: A 14-year-old female spayed Abyssinian cat, which about 1 year previously underwent thoracic limb amputation, radiotherapy and chemotherapy for an incompletely excised vaccine-related fibrosarcoma, was presented for evaluation of corneal opacity in the left eye (OS). The ocular surface of both eyes (OU) had a lackluster appearance and there was a stromal corneal ulcer OS. Results of corneal aesthesiometry, Schirmer tear test-1 (STT-1) and tear film breakup time revealed corneal hypoesthesia, and quantitative and qualitative tear film deficiency OU...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29305607/novel-insight-into-the-role-of-cftr-in-lacrimal-gland-duct-function-in-mice
#5
Orsolya Berczeli, Eszter Vizvári, Máté Katona, Dénes Török, László Szalay, Ferenc Rárosi, István Németh, Zoltán Rakonczay, Péter Hegyi, Chuanqing Ding, Edit Tóth-Molnár
Purpose: The role of cystic fibrosis transmembrane conductance regulator (CFTR) in lacrimal gland (LG) function has only recently received some attention, mainly from our group. In the present study, we investigated the potential changes of LG pathology, tear secretion, ocular surface integrity, and fluid secretion in isolated LG ducts from CFTR knockout (KO) mice. Methods: Tear production and ocular surface integrity were investigated in anesthetized wild-type (WT) and KO mice using cotton threads and fluorescein staining, respectively...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29302763/reduced-myofilament-component-in-primary-sj%C3%A3-gren-s-syndrome-salivary-gland-myoepithelial-cells
#6
Margherita Sisto, Loredana Lorusso, Giuseppe Ingravallo, Roberto Tamma, Beatrice Nico, Domenico Ribatti, Simona Ruggieri, Sabrina Lisi
Primary Sjögren's syndrome (pSS) is a solitary poorly understood autoimmune inflammatory disease by involvement of the salivary and lacrimal glands resulting in dry mouth and dry eyes. Myoepithelial cells (MECs) are cells knowing for its hybrid epithelial and mesenchymal phenotype that are important components of the salivary gland (SGs) structure aiding the expulsion of saliva from acinar lobules. In this study we investigate possible alteration in the myofilament component of MECs in SGs specimens obtained from pSS patients in comparison with healthy subjects, to evaluate MECs hypothetical involvement in the pathogenesis of pSS...
January 4, 2018: Journal of Molecular Histology
https://www.readbyqxmd.com/read/29299096/a-case-report-of-mikulicz-syndrome
#7
Dinesh Rao, Patrick Natter, Rui Fernandes, Zhiqiang Brad Wang, Sukhwinder Johnny Singh Sandhu
Mikulicz Syndrome (MS) is a rare chronic condition characterized by the abnormal enlargement of glandular tissue in the head and neck. Patients usually present with enlarged lacrimal and parotid glands. While this can be a benign self-limiting condition, other complex systemic diseases, such as sarcoidosis, may represent other underlying etiologies. We present a case of MS in a patient with a history of Crohn's disease.
July 2017: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29297564/oral-nodular-lesions-in-patients-with-sj%C3%A3-gren-s-syndrome-unusual-oral-implications-of-a-systemic-disorder
#8
Juliana Barchelli Pinheiro, Camila Tirapelli, Claudia Helena Lovato da Silva, Marilena Chinali Komesu, Flávio Calil Petean, Paulo Louzada Junior, Jorge Esquiche León, Ana Carolina Fragoso Motta
Sjögren's syndrome (SS) is a systemic chronic autoimmune disorder affecting the lacrimal and salivary glands. SS may manifest as primary SS (pSS) or secondary SS (sSS), the latter occurring in the context of another autoimmune disorder. In both cases, the dry eyes and mouth affect the patient's quality of life. Late complications may include blindness, dental tissue destruction, oral candidiasis and lymphoma. This paper reports two cases of SS, each of them presenting unusual oral nodular lesion diagnosed as relapsed MALT lymphoma and mucocele...
May 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29288833/lacrimal-gland-abscess-in-a-child-as-a-rare-manifestation-of-igg4-related-disease
#9
Edward L Raab, Hamideh S Moayedpardazi, Steven M Naids, Alan H Friedman, Murray A Meltzer
Dacryoadenitis is unusual in children, and noninfectious causes can be manifestations of serious undiagnosed systemic conditions. This report brings further attention to this rarely-encountered condition and emphasizes its association with IgG4-related disease, a group of inflammatory disorders of high current interest whose spectrum of manifestations continues to evolve. The pediatric ophthalmologist could be in the position of identifying a patient's serious and previously unappreciated illness.
December 27, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29286080/a-murine-model-of-dry-eye-induced-by-topical-administration-of-erlotinib-eye-drops
#10
Qi-Chen Yang, Jing Bao, Cheng Li, Gang Tan, An-Hua Wu, Lei Ye, Lin-Hong Ye, Qiong Zhou, Yi Shao
In the present study, the effects of erlotinib on mouse tear function and corneal epithelial tissue structure were investigated. Throughout the 3 weeks of treatment, no notable differences were observed in the body, eye or lacrimal gland weights of the control and experimental mice. However, in the experimental group, the tear volume and break‑up times of tear film were significantly lower following treatment with erlotinib compared with the control group. Corneal fluorescein staining in the experimental group revealed patchy staining, and the Lissamine green staining and inflammatory index were significantly higher in the experimental group at 3 weeks than in the control group...
December 29, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29283151/unusual-intraconal-localization-of-orbital-giant-cell-angiofibroma
#11
Meryem Altin Ekin, Seyda Karadeniz Ugurlu, Fulya Cakalagaoglu
Giant cell angiofibroma (GCA) is a recently reported rare soft-tissue tumor that can develop in various sites including orbit. Orbital GCAs were mainly located in the eyelid or extraconal regions such as lacrimal gland and conjunctiva. We report an atypical case of a GCA arising in the intraconal area of the orbit in a 65-year-old male patient. The tumor was excised in total by lateral orbitotomy. Histological and immunohistochemical features were consistent with the diagnosis of GCA. No recurrence was observed during the follow-up of over 2 years...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29279552/nephrotic-syndrome-during-the-tapering-of-oral-steroids-after-pathological-diagnosis-of-kimura-disease-from-a-lacrimal-gland-mass-case-report-and-review-of-10-japanese-patients
#12
Toshihiko Matsuo, Takehiro Tanaka, Masaru Kinomura
A 42-year-old man with eosinophilia and high serum immunoglobulin E (IgE) developed a lacrimal gland mass on the left side. Excisional biopsy revealed hyperplasia of lymphoid follicles, and infiltration with lymphocytes and eosinophils around lacrimal gland acini, leading to the pathological diagnosis of Kimura disease. IgE-positive cells were mainly found along follicular dendritic cells, and a small number of IgG4-positive cells was present. One month after oral prednisolone was started at 40 mg daily and tapered to 10 mg daily, he developed lower leg edema on both sides and marked proteinuria (10...
2017: Journal of Clinical and Experimental Hematopathology: JCEH
https://www.readbyqxmd.com/read/29260748/-necrotizing-sarcoid-granulomatosis-with-clinical-presentations-of-recurrent-acute-abdomen-case-report-and-literature-review
#13
V I Vasilyev, S G Palshina, B D Chaltsev, S G Radenska-Lopovok, T N Safonova
The authors have described the world's first case of necrotizing sarcoid granulomatosis (NSG) in a 22-year-old woman with the clinical presentations of acute abdomen, which are associated with abdominal lymph nodal infiltration and necrosis, obvious constitutional disturbances (fever, nocturnal sweats, and significant weight loss), high inflammatory activity (anemia, leukocytosis, high erythrocyte sedimentation rates and C-reactive protein levels), the gradual appearance of splenic and hepatic necrotic foci, and infiltration into the lung and lacrimal glands with the development of unilateral uveitis...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29251639/mammary-analog-secretory-carcinoma-with-etv6-rearrangement-arising-in-the-conjunctiva-and-eyelid
#14
Yongyang Bao, Jiang Li, Yanbo Zhu
Mammary analog secretory carcinoma (MASC) of salivary gland is a recently described neoplasm that morphologically and immunohistochemically resembles secretory carcinoma of the breast. Genetically, both of them harbor ETV-6-NTRK-3 fusion rearrangement. One case of primary MASCs arising from the eyelid is reported. The patient was a 52-year-old man. Microscopically, the tumor exhibited nodular aggregation of solid, tubular, and microcystic/macrocystic structures. Characteristic "colloid-like" eosinophilic secretory material was present within intraluminal spaces...
November 28, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29242401/eboni-a-tool-for-automated-quantification-of-bone-metastasis-load-in-psma-pet-ct
#15
Jochen Hammes, Philipp Täger, Alexander Drzezga
PSMA PET/CT has a high diagnostic accuracy for lesion detection in metastatic prostate cancer (MPC), including bone metastases. Novel therapeutic approaches require valid biomarkers for standardized disease staging, progression and therapy response. Here, we introduce EBONI (Evaluation of Bone Involvement), a software to automatically quantify bone metastasis load in PSMA PET/CT. Lesion quantity, mean and maximum lesional standardized uptake value (SUV), Z-Score and percentage of affected bone volume are determined...
December 14, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29235530/tri-microspheres-prevent-key-signs-of-dry-eye-disease-in-a-murine-inflammatory-model
#16
Michelle L Ratay, Stephen C Balmert, Abhinav P Acharya, Ashlee C Greene, Thiagarajan Meyyappan, Steven R Little
Dry eye disease (DED) is a highly prevalent, ocular disorder characterized by an abnormal tear film and ocular surface. Recent experimental data has suggested that the underlying pathology of DED involves inflammation of the lacrimal functional unit (LFU), comprising the cornea, conjunctiva, lacrimal gland and interconnecting innervation. This inflammation of the LFU ultimately results in tissue deterioration and the symptoms of DED. Moreover, an increase of pathogenic lymphocyte infiltration and the secretion of pro-inflammatory cytokines are involved in the propagation of DED-associated inflammation...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29234229/isolated-bilateral-congenital-lacrimal-gland-agenesis-report-of-two-cases
#17
Manar Alwohaib, Silvana Artioli Schellini, Sahar M Elkhamary, Osama Al Shaikh
Congenital lacrimal gland agenesis, also called congenital alacrima, is a rare cause of dry eye and is characterized by aplasia or hypoplasia of lacrimal glands. We present two 5-year old children with congenital lacrimal gland agenesis. The two cases had the final diagnosis of isolated bilateral congenital lacrimal gland agenesis and we document the clinical aspects, treatment and present a literature review related to this rare condition.
October 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29222450/elevation-of-autophagy-markers-in-sj%C3%A3-gren-syndrome-dry-eye
#18
Yong-Soo Byun, Hyun Jung Lee, Soojung Shin, So-Hyang Chung
Autophagy is known to be implicated in the pathogenesis of Sjögren syndrome (SS), but evidences are limited. We aimed to examine the levels of autophagy markers in tear film and conjunctival epithelial cells from SS dry eye patients, and analyze their correlations with clinical features. Patients with SS dry eye exhibited lower Schirmer values, lower tear breakup time, and higher ocular staining scores. In tears, ATG5 and LC3B-II/I levels were significantly higher in SS dry eye. ATG5 and LC3B-II mRNA in the conjunctiva were also elevated in SS dry eye compared with non-SS dry eye...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29204759/ocular-manifestations-of-igg4-related-disease-in-children-more-common-than-anticipated-review-of-the-literature-and-case-report
#19
REVIEW
Roubini G Smerla, Dimitra Rontogianni, George E Fragoulis
IgG4-related disease (IgG4-RD) is an entity with various clinical manifestations. Histopathologically, it is characterized by lymphoplasmacytic infiltrates enriched in IgG4 (+) plasmacytes and usually fibrosis of the affected tissue. Most of the patients have also increased IgG4 serum levels and they respond to glucocorticosteroids. In children, due to its rare occurrence, IgG4-RD is ill defined. From the published studies, so far, it appears that ocular manifestations are very common in the paediatric population with IgG4-RD...
December 4, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29201576/anatomical-study-of-the-zygomaticotemporal-branch-inside-the-orbit
#20
Joe Iwanaga, Charlotte Wilson, Koichi Watanabe, Rod J Oskouian, R Shane Tubbs
The location of the opening of the zygomaticotemporal branch (ZTb) of the zygomatic nerve inside the orbit (ZTFIN) has significant surgical implications. This study was conducted to locate the ZTFIN and investigate the variations of the ZTb inside the orbit. A total of 20 sides from 10 fresh frozen cadaveric Caucasian heads were used in this study. The vertical distance between the inferior margin of the orbit and ZTFIN (V-ZTFIN), the horizontal distance between the lateral margin of the orbit and ZTFIN (H-ZTFIN), and the diameter of the ZTFIN (D-ZTFIN) were measured...
September 29, 2017: Curēus
keyword
keyword
120715
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"