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Lacrimal duct

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https://www.readbyqxmd.com/read/28717520/modeling-chronic-dacryocystitis-in-rabbits-by-nasolacrimal-duct-obstruction-with-self-curing-resin
#1
Kai Hou, Tao Ai, Rong Liu, Nan Xiang, Jing Jin, Weikun Hu, Ban Luo
We established a chronic dacryocystitis model by injecting of 0.05, 0.1, and 0.15 ml self-curing resin via the lacrimal punctum in rabbits. Animals were randomized into four groups (n = 11 animals/group). The control group received 0.15 ml normal saline. Within three months postinjection, epiphora and eye discharge were observed. At the 90th day postlacrimal passage irrigation, CT dacryocystography was performed to find changes in the lacrimal image, and hematoxylin and eosin staining was made to identify pathological changes of the lacrimal sac...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28700811/probing-for-congenital-nasolacrimal-duct-obstruction
#2
REVIEW
Carisa Petris, Don Liu
BACKGROUND: Congenital nasolacrimal duct obstruction (NLDO) is a common condition causing excessive tearing in the first year of life. Infants present with excessive tearing or mucoid discharge from the eyes due to blockage of the nasolacrimal duct system, which can result in maceration of the skin of the eyelids and local infections, such as conjunctivitis, that may require antibiotics. The incidence of nasolacrimal duct obstruction in early childhood ranges from 5% to 20% and often resolves without surgery...
July 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28698824/on-the-tear-proteome-of-the-house-mouse-mus-musculus-musculus-in-relation-to-chemical-signalling
#3
Romana Stopkova, Petr Klempt, Barbora Kuntova, Pavel Stopka
Mammalian tears are produced by lacrimal glands to protect eyes and may function in chemical communication and immunity. Recent studies on the house mouse chemical signalling revealed that major urinary proteins (MUPs) are not individually unique in Mus musculus musculus. This fact stimulated us to look for other sexually dimorphic proteins that may-in combination with MUPs-contribute to a pool of chemical signals in tears. MUPs and other lipocalins including odorant binding proteins (OBPs) have the capacity to selectively transport volatile organic compounds (VOCs) in their eight-stranded beta barrel, thus we have generated the tear proteome of the house mouse to detect a wider pool of proteins that may be involved in chemical signalling...
2017: PeerJ
https://www.readbyqxmd.com/read/28691455/adult-syndrome-dental-features-of-a-very-rare-condition
#4
L Azzi, V Maurino, R Vinci, F Croveri, A Boggio, A Tagliabue, J Silvestre-Rangil
The Acro-Dermato-Ungual-Lacrimal-Tooth syndrome (ADULT syndrome) is one of the rarest ectodermal dysplasias and it is associated with several malformations involving especially the limbs. The most clinical features are the presence of ectrodactyly, syndactyly, hypermelanosis or multiple lentigines, onhycodysplasia, abnormalities in the lacrimal duct, recurrent conjuntivitis, photophobia, mammarian hypoplasia, hypotrichosis and frontal alopecia, hypohydrosis, cutaneous photosensitivity, nasal bridge prominence, exfoliative dermatitis and xerosis...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28687815/postoperative-long-term-morbidity-of-extended-endoscopic-maxillectomy-for-inverted-papilloma
#5
G Bertazzoni, R Accorona, A Schreiber, G Pietrobon, A Karligkiotis, E Fazio, P Castelnuovo, P Nicolai
BACKGROUND: Extended endoscopic maxillectomy (Sturmann-Canfield procedure) allows full visualization of the maxillary sinus by sectioning the lacrimal duct and removing the medial part of the anterior maxillary wall. The aim of this study is to evaluate the morbidity of Sturmann-Canfield procedure in patients treated for inverted papilloma. METHODOLOGY: The clinical records of all patients treated with a Sturmann-Canfield procedure for inverted papilloma from October 2000 to September 2015 at two teaching hospitals were reviewed...
July 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28683481/-recanalization-of-lacrimal-duct-stenosis-by-laserdacryoplasty-using-a-diode-laser-comparison-of-success-rates-using-an-erbium%C3%A2-%C3%A2-yag-laser
#6
Ludwig Stock, Ralf Ungerechts, Karl-Heinz Emmerich
Background In a retrospective study, the success rates of laserdacryoplasty using a diode laser were defined and compared to success rates using an erbium : YAG laser. Using a diode laser at a wave length of 980 nm, thermal destruction of tissue leads to recanalization. Using an erbium : YAG laser at a wave length of 2940 nm, recanalization of punctual stenosis is achieved by formation of a cavitation bubble in a closed system. Materials and Methods 94 patients (64 women, 30 men, mean age 60.8 years) with 107 absolute lacrimal duct stenoses who were treated by laserdacryoplasty using a diode laser were included in a retrospective study...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28648105/abnormal-distribution-of-aqp4-in-minor-salivary-glands-of-primary-sj%C3%A3-gren-s-syndrome-patients
#7
Margherita Sisto, Loredana Lorusso, Giuseppe Ingravallo, Beatrice Nico, Domenico Ribatti, Simona Ruggieri, Dario Domenico Lofrumento, Sabrina Lisi
A decreased saliva production occurs in primary Sjögren's syndrome (pSS), an autoimmune disease characterized by oral and ocular dryness due to dysfunction of the lacrimal and salivary glands (SGs). Since water movement is involved in saliva secretion, the expression, localization, and function of the water channels aquaporins (AQPs) have been extensively studied in SGs. To date, the presence of AQP4 remains controversial and ambiguous in human SGs. We investigated by immunohistochemistry, high-resolution confocal microscopy and quantitative image analysis, Western blot and real-time RT-PCR, the presence of the AQP4 gene, and the distribution of AQP4 protein in healthy controls and pSS SG biopsies...
June 24, 2017: Autoimmunity
https://www.readbyqxmd.com/read/28636742/results-of-endonasal-dacryocystorhinostomy-in-pediatric-patients
#8
Sat Paul Gulati, Raman Wadhera, Ashok Kumar Khurana, Nidhi Singh, Vijay Kalra, Anju Ghai
We conducted a prospective interventional study to evaluate the role of endoscopic endonasal dacryocystorhinostomy in children. Our study population was made up of 20 patients-18 boys and 2 girls, aged 2 to 12 years (mean: 5.3)-who presented with signs and symptoms suggestive of nasolacrimal duct blockage that was refractory to conventional medical treatment. In all cases, blockage was confirmed by nasolacrimal duct syringing that demonstrated regurgitation from the opposite punctum. The primary outcome measures for success were resolution of symptoms and duct patency on lacrimal irrigation...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28634110/pharmacological-rescue-of-ductal-cftr-rescue-pancreatic-and-salivary-glands-acinar-cells-and-tissue-function-in-mouse-models-of-autoimmune-diseases
#9
Mei Zeng, Mitchell Szymczak, Malini Ahuja, Changyu Zheng, Hongen Yin, William Swaim, John A Chiorini, Robert J Bridges, Shmuel Muallem
BACKGROUND & AIMS: Sjögren's syndrome and autoimmune pancreatitis (AIP) are disorders with decreased function of salivary, lacrimal glands, and the exocrine pancreas. NOD/ShiLTJ mice and mice transduced with the cytokine BMP6 develop Sjögren's syndrome and chronic pancreatitis and MRL/Mp mice are models of AIP. CFTR is a ductal Cl(-) channel essential for ductal fluid and HCO3(-) secretion. We used these models to ask: is CFTR expression altered in these diseases, does correction of CFTR correct gland function, and most notably, does correcting ductal function correct acinar function...
June 17, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28598869/graft-versus-host-disease-what-should-the-oculoplastic-surgeon-know
#10
Cynthia I Tung
PURPOSE OF REVIEW: To provide a concise review of the oculoplastic manifestations of ocular graft versus host disease (GVHD), and to discuss their management. RECENT FINDINGS: Ocular GVHD occurs as a common immune-mediated complication of hematopoietic stem cell transplantation that presents as a Stevens-Johnson-like syndrome in the acute phase or a Sjögren-like syndrome in the chronic phase. Cicatricial conjunctivitis may be underreported in ocular GVHD. The spectrum of oculoplastic manifestations includes GVHD of the skin, cicatricial entropion, nasolacrimal duct obstruction, and lacrimal gland dysfunction...
June 8, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28570687/intervention-using-a-novel-biodegradable-hollow-stent-containing-polylactic-acid-polyprolactone-polyethylene-glycol-complexes-against-lacrimal-duct-obstruction-disease
#11
Xinyuan Zhan, Xin Guo, Rong Liu, Weikun Hu, Lei Zhang, Nan Xiang
Lacrimal duct obstruction disease (LDOD) is a common ophthalmologic disease. Stent implantation surgery is one of the most effective therapies. In this study, we intended to find out the satisfactory biodegradable stents containing poly-L-lactic acid-polycaprolactone-polyethylene glycol (PLLA- PCL- PEG) complexes for therapeutic application in LDOD. Stents made of PLLA- PCL- PEG complexes in various ratios, were prepared and used in vitro to determine stents with appropriate mechanical properties and shorter range of bio-degradation for study in vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28550338/a-comparative-study-of-modified-transcanalicular-diode-laser-dacryocystorhinostomy-versus-conventional-transcanalicular-diode-laser-dacryocystorhinostomy
#12
Eduardo Damous Feijó, Juliana Alves Caixeta, Ana Carla de Souza Nery, Roberto Murillo Limongi, Suzana Matayoshi
External dacryocystorhinostomy (DCR) is the gold standard surgical technique for the treatment of primary acquired nasolacrimal duct obstruction (PANDO). However, new techniques such as endoscopic DCR and transcanalicular dacryocystorhinostomy (T-DCR) are being studied in an attempt to reduce surgical time, avoid external scarring and preserve the lacrimal pump while achieving the same efficacy. The purpose of this study was to compare the efficacy between conventional T-DCR and modified transcanalicular dacryocystorhinostomy (MT-DCR) in patients with PANDO...
August 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28510777/anatomical-characterization-of-the-nasolacrimal-canal-based-on-computed-tomography-in-children-with-complex-congenital-nasolacrimal-duct-obstruction
#13
Chengyue Zhang, Gang Yu, Yanhui Cui, Qian Wu, Wenbin Wei
PURPOSE: To characterize anatomical variations of the nasolacrimal canal in patients with complex congenital nasolacrimal duct obstruction. METHODS: Retrospective case series of 25 children with congenital nasolacrimal duct obstruction. All children had failed probings and were examined by computed tomography. An analysis of imaging data is presented. RESULTS: Anomalous development of the nasolacrimal canal was confirmed on computed tomography...
May 15, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28509331/anatomic-landmarks-in-lacrimal-surgery-from-an-ophthalmologist-s-point-of-view
#14
REVIEW
Jens Heichel, Hans-Gert Struck, Anja Viestenz, Thomas Hammer, Arne Viestenz, Miltiadis Fiorentzis
Epiphora is a common clinical symptom of nasolacrimal duct obstruction. However, it is present in several pathologies and can lead to decreased quality of life for patients. A careful clinical examination including a detailed patient's history and diagnostic tests such as the fluorescein dye disappearance test and diagnostic syringing of the lacrimal duct are essential. Depending on the time of presentation (congenital, primary or secondary acquired), grade (subtotal or total) and location of the stenosis, different surgical approaches can be considered...
May 16, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28490404/causes-of-dacryocystorhinostomy-failure-external-versus-endoscopic-approach
#15
Giant C Lin, Christopher D Brook, Mark P Hatton, Ralph Metson
OBJECTIVES: To compare the causes of failure between external and endoscopic dacryocystorhinostomy (DCR) techniques for the treatment of lacrimal obstruction. STUDY DESIGN: A retrospective cohort study. METHODS: The study population consisted of 53 consecutive patients who underwent revision endoscopic DCR from 2002 to 2013 for lacrimal duct obstruction. Identified causes of previous DCR failure were compared between patients whose initial surgery was performed through an external versus an endoscopic approach...
May 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28470654/-dacryoliths-and-iatrogenic-foreign-bodies-as-classical-triggers-for-inflammatory-pseudotumors-of-the-lacrimal-drainage-system
#16
J Heichel, C Neumann, D Bethmann, U Siebolts, T Hammer, H-G Struck
Background Tumors of the lacrimal duct are rare. Inflammatory pseudotumors do not represent neoplasias as such. Chronic inflammation may lead to an angiomatous granulation tissue. Patients The first case presents a 53-year-old male patient suffering a mass of the mediocaudal orbit after an acute dacryocystitis has been cured. Using diagnostic dacryoendoscopy, a large dacryolith was detected. Removing the concrement, via external dacryocystorhinostomy, a polypous tissue appeared which was resected as well. The second case concerns a 29-year-old female patient...
May 3, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28430706/rare-pleurostomophora-richardsiae-mass-causing-transient-nasolacrimal-duct-obstruction
#17
Md Shahid Alam, D Vaidehi, K Lily Therese, Mohammad Javed Ali
Transient nasolacrimal duct obstruction secondary to a mass lesion compressing the sac or sac-duct junction is rare. We report a case of a young female who presented to us with complaints of watering and a mass lesion in the lacrimal sac region. An organized perilacrimal mass filled with thick pultaceous material was noted during surgery. Following the drainage of the mass lesion, irrigation of the lacrimal system was freely patent. Microbiological examination and DNA sequencing targeting interspacer region was suggestive of Pleurostomophora richardsiae species...
April 20, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28410267/lacrimal-sac-pneumatocele-following-blunt-nasal-trauma
#18
Sima Das, Mohammad Javed Ali, Smriti Bansal, Manpreet Chugh, Nishi Gupta, Vidya Janaki
Pneumatocele of the lacrimal sac is an uncommon entity and has been rarely reported in literature. The valvular function of the Hasner's valve at the lower end of nasolacrimal duct is presumed to prevent the retrograde reflux of air into the lacrimal sac with increased intranasal pressure as in valsalva maneuver. Loss of this valvular function as noted with persistent positive airway pressure ventilation can cause retrograde air reflux into lacrimal sac. The authors report a case of lacrimal sac pneumatocele which developed following blunt nasal trauma involving the bony nasolacrimal duct...
April 13, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28380654/-graduated-treatment-concept-for-connatal-dacryostenosis
#19
J Heichel
Unresolved epiphora in childhood is one of the most frequent issues in paediatric ophthalmology. In this context, connatal nasolacrimal duct obstruction (CNLDO) is the most important differential diagnosis and the condition is caused by a persistent Hasner's membrane in most cases. As there is a risk of complications, treatment should be considered. Therapeutic options include conservative and invasive approaches. As CNLDO is associated with high spontaneous recovery rates during the first years of life, the indication for invasive interventions must be carefully deliberated in that period...
April 5, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28374054/-tuna-saving-endoscopic-medial-maxillectomy-a-surgical-technique-for-maxillary-inverted-papilloma
#20
Fabio Pagella, Alessandro Pusateri, Elina Matti, Irene Avato, Dario Zaccari, Enzo Emanuelli, Tiziana Volo, Diego Cazzador, Leonardo Citraro, Giampiero Ricci, Giovanni Leo Tomacelli
The maxillary sinus is the most common site of sinonasal inverted papilloma. Endoscopic sinus surgery, in particular endoscopic medial maxillectomy, is currently the gold standard for treatment of maxillary sinus papilloma. Although a common technique, complications such as stenosis of the lacrimal pathway and consequent development of epiphora are still possible. To avoid these problems, we propose a modification of this surgical technique that preserves the head of the inferior turbinate and the nasolacrimal duct...
April 3, 2017: European Archives of Oto-rhino-laryngology
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