Valentina Giudice, Monica Ianniello, Danilo De Novellis, Luca Pezzullo, Nadia Petrillo, Bianca Serio, Matteo D'Addona, Anna Maria Della Corte, Michela Rizzo, Bianca Cuffa, Maria Antonietta Castaldi, Pasquale Savarese, Alessio Mori, Rosa Castiello, Antonio Fico, Giovanni Savarese, Carmine Selleri
Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-free DNA (cfDNA). The aim of this study was to investigate feasibility, sensitivity, and specificity of non-invasive prenatal test (NIPT) for identification of chromosomal abnormalities in cfDNA from a total of 77 consecutive patients with non-Hodgkin B-cell lymphomas, Hodgkin lymphoma (HL), or plasma cell dyscrasia. In this case series, half of patients had at least one alteration, more frequently in chromosome 6 (23...
April 5, 2024: Clinical and Experimental Medicine