keyword
MENU ▼
Read by QxMD icon Read
search

Radiation

keyword
https://www.readbyqxmd.com/read/28103659/-a-case-of-giant-prostate-carcinoma-effectively-treated-with-external-beam-radiation-therapy
#1
Sohei Kanda, Shintaro Narita, Naoki Komine, Seiichi Kitajima, Misa Yamauchi, Akihiro Sugita, Yutaka Saito, Tomonori Habuchi
We present a case of gigantic prostate tumor in a patient with castration-resistant prostate cancer with successful local control by external-beam radiation therapy. A 71-year-old man was shown to have a prostate specific antigen (PSA)level of 24.5 ng/ml, Gleason 9, cT2N1M1a, prostate adenocarcinoma with an estimated prostate volume of 26.9 g. He achieved a PSA nadir at 4 months after the initial androgen deprivation therapy and was diagnosed with castration-resistant prostate cancer three years later. Eight months after the diagnosis of castration-resistant prostate cancer, he visited our hospital due to urinary retention...
December 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28103658/-etoposide-and-carboplatin-effective-for-treatment-of-small-cell-carcinoma-of-prostate-a-report-of-two-cases
#2
Satoru Yumiba, Toshihisa Asakura, Takayuki Okada, Mototaka Satoh, Mikio Nin, Masao Tsujihata
Case 1 : A 76-year-old man consulted a physician because of pollakisuria, decline of urinary stream. A high level of serum prostate specific antigen (PSA) was detected and he came to our hospital. He was diagnosed to have prostate cancer, cT3aN0M1b, and was treated with combined androgen blockage (CAB). Two years and nine months later, postrenal failure appeared and serum level of neuron-specific enolase (NSE) was 162 ng/ml. We performed re-biopsy of prostate, and pathological examination indicated small cell carcinoma of the prostate...
December 2016: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28103615/radiation-induced-lung-metastasis-development-is-mt1-mmp-dependent-in-a-triple-negative-breast-cancer-mouse-model
#3
Gina Bouchard, Hélène Therriault, Sameh Geha, Rachel Bujold, Caroline Saucier, Benoit Paquette
BACKGROUND: The prognosis of triple-negative breast cancer (TNBC) is still difficult to establish. Some TNBC benefit from radiotherapy (RT) and are cured, while in other patients metastases appear during the first 3 years after treatment. In this study, an animal model of TNBC was used to determine whether the expression of the cell membrane protease MT1-MMP in cancer cells was associated with radiation-stimulated development of lung metastases. METHODS: Using invasion chambers, irradiated fibroblasts were used as chemoattractants to assess the invasiveness of TNBC D2A1 cell lines showing downregulated expression of MT1-MMP, which were compared with D2A1-wt (wild-type) and D2A1 shMT1-mock (empty vector) cell lines...
January 19, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28103571/identification-of-aurintricarboxylic-acid-as-a-selective-inhibitor-of-the-tweak-fn14-signaling-pathway-in-glioblastoma-cells
#4
Alison Roos, Harshil D Dhruv, Ian T Mathews, Landon J Inge, Serdar Tuncali, Lauren K Hartman, Donald Chow, Nghia Millard, Holly H Yin, Jean Kloss, Joseph C Loftus, Jeffrey A Winkles, Michael E Berens, Nhan L Tran
The survival of patients diagnosed with glioblastoma (GBM), the most deadly form of brain cancer, is compromised by the proclivity for local invasion into the surrounding normal brain, which prevents complete surgical resection and contributes to therapeutic resistance. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK), a member of the tumor necrosis factor (TNF) superfamily, can stimulate glioma cell invasion and survival via binding to fibroblast growth factor-inducible 14 (Fn14) and subsequent activation of the transcription factor NF-κB...
January 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28103445/factors-influencing-radiation-treatment-recommendations-in-early-stage-merkel-cell-carcinoma-a-survey-of-us-based-radiation-oncologists
#5
Yolanda D Tseng, Smith Apisarnthanarax, Jay J Liao, Shailender Bhatia, Paul T Nghiem, Upendra Parvathaneni
OBJECTIVES: It is unclear which subgroups of Merkel cell carcinoma (MCC) patients benefit the most from radiation. We surveyed radiation oncologists (RO) that regularly see and treat MCC to understand how they approach the treatment of early-stage MCC. METHODS: A web-based survey was emailed to 63 ROs, who were identified through publications, guideline panel membership, and/or affiliation with institutions of high MCC volume. ROs provided treatment recommendations for two hypothetical case scenarios of early stage MCC...
January 19, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28103307/plant-family-specific-impacts-of-petroleum-pollution-on-biodiversity-and-leaf-chlorophyll-content-in-the-amazon-rainforest-of-ecuador
#6
Paul Arellano, Kevin Tansey, Heiko Balzter, Markus Tellkamp
In recent decades petroleum pollution in the tropical rainforest has caused significant environmental damage in vast areas of the Amazon region. At present the extent of this damage is not entirely clear. Little is known about the specific impacts of petroleum pollution on tropical vegetation. In a field expedition to the Ecuadorian Amazon over 1100 leaf samples were collected from tropical trees in polluted and unpolluted sites. Plant families were identified for 739 of the leaf samples and compared between sites...
2017: PloS One
https://www.readbyqxmd.com/read/28103177/hbxip-a-binding-protein-of-hbx-regulates-maintenance-of-the-g2-m-phase-checkpoint-induced-by-dna-damage-and-enhances-sensitivity-to-doxorubicin-induced-cytotoxicity
#7
Hong-Rong Fei, Yun-Sheng Zhou, Ruo-Tong Li, Ming-Feng Yang, Jian Ma, Feng-Ze Wang
To maintain the integrity of the genome, cells need to detect and repair DNA damage before they complete cell division. Hepatitis B x-interacting protein (HBXIP), a binding protein of HBx (Hepatitis B virus x protein), is aberrantly overexpressed in human cancer cells and show to promote cell proliferation and inhibit apoptosis. The present study is designed to investigate the role of HBXIP on the DNA damage response. Our results show that HBXIP acts as an important regulator of G2/M checkpoint in response to DNA damage...
January 19, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28103113/micronuclei-as-a-marker-for-medical-screening-of-subjects-continuously-occupationally-exposed-to-low-doses-of-ionizing-radiation
#8
Smj Mortazavi, Sar Mortazavi, Maryam Paknahad
No abstract text is available yet for this article.
January 19, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28103107/star-masses-and-star-planet-distances-for-earth-like-habitability
#9
David Waltham
This paper presents statistical estimates for the location and duration of habitable zones (HZs) around stars of different mass. The approach is based upon the assumption that Earth's location, and the Sun's mass, should not be highly atypical of inhabited planets. The results support climate-model-based estimates for the location of the Sun's HZ except models giving a present-day outer-edge beyond 1.64 AU. The statistical approach also demonstrates that there is a habitability issue for stars smaller than 0...
January 2017: Astrobiology
https://www.readbyqxmd.com/read/28102961/assessing-the-use-of-4dct-ventilation-in-pre-operative-surgical-lung-cancer-evaluation
#10
Yevgeniy Vinogradskiy, Matthew Jackson, Leah Schubert, Bernard Jones, Richard Castillo, Edward Castillo, Thomas Guerrero, John Mitchell, Chad Rusthoven, Moyed Miften, Brian Kavanagh
PURPOSE: A primary treatment option for lung cancer patients is surgical resection. Patients who have poor lung function prior to surgery are at increased risk of developing serious and life-threatening complications after surgical resection. Surgeons use nuclear medicine ventilation-perfusion (VQ) scans along with pulmonary function test (PFT) information to assess a patient's pre-surgical lung function. The nuclear medicine images and pre-surgery PFTs are used to calculate percent predicted postoperative (%PPO) PFT values by estimating the amount of functioning lung tissue that would be lost with surgical resection...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102958/sliding-window-prior-data-assisted-compressed-sensing-for-mri-tracking-of-lung-tumors
#11
Eugene Yip, Jihyun Yun, Keith Wachowicz, Zsolt Gabos, Satyapal Rathee, B G Fallone
PURPOSE: Hybrid magnetic resonance imaging and radiation therapy devices are capable of imaging in real-time to track intrafractional lung tumor motion during radiotherapy. Highly accelerated magnetic resonance (MR) imaging methods can potentially reduce system delay time and/or improves imaging spatial resolution, and provide flexibility in imaging parameters. Prior Data Assisted Compressed Sensing (PDACS) has previously been proposed as an acceleration method that combines the advantages of 2D compressed sensing and the KEYHOLE view-sharing technique...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102956/experimental-verification-of-4d-monte-carlo-simulations-of-dose-delivery-to-a-moving-anatomy
#12
Sara Gholampourkashi, Miro Vujicic, Jason Belec, Joanna E Cygler, Emily Heath
PURPOSE: To evaluate a novel 4D Monte Carlo simulation tool by comparing calculations to physical measurements using a respiratory motion phantom. METHODS: We used a dynamic Quasar phantom in both stationary and breathing states (sinusoidal motion of amplitude of 1.8 cm and period of 3.3 s) for dose measurements on an Elekta Agility linear accelerator. Gafchromic EBT3 film and the RADPOS 4D dosimetry system were placed inside the lung insert of the phantom to measure dose profiles and point-dose values at the center of the spherical tumor inside the insert...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102954/dosimetric-impact-of-lipiodol-in-stereotactic-body-radiation-therapy-on-liver-after-trans-arterial-chemoembolization
#13
Daisuke Kawahara, Shuichi Ozawa, Akito Saito, Teiji Nishio, Tomoki Kimura, Tatsuhiko Suzuki, Kazunari Hioki, Takeo Nakashima, Yoshimi Ohno, Yuji Murakami, Yasushi Nagata
PURPOSE: Stereotactic body radiation therapy (SBRT) combining trans-arterial chemoembolization (TACE) with Lipiodol is expected to improve local control. This study is aimed to estimate the dose enhancement in Lipiodol's proximity and to evaluate the dose calculation accuracy of the Acuros XB (AXB) algorithm and anisotropic analytical algorithm (AAA) in the Eclipse treatment planning system (TPS) (ver. 11, Varian Medical Systems, Palo Alto, USA), compared with that of the Monte Carlo (MC) calculation (using BEAMnrc/DOSXYZnrc code) for a virtual phantom and a treatment plan for liver SBRT after TACE...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102953/air-kerma-strength-determination-of-an-hdr-192-ir-source-including-a-geometric-sensitivity-study-of-the-seven-distance-method
#14
Blake R Smith, John A Micka, Manik Aima, Larry A DeWerd, Wesley S Culberson
PURPOSE: To perform an in-air air-kerma strength (SK) calibration of the Bebig model Ir2.A85-2 192Ir high-dose rate (HDR) brachytherapy source manufactured by Mallinckrodt Medical (Westerduinweg, Germany) with the NIST-traceable seven-distance technique established by the University of Wisconsin. A comparison was made between the reference air-kerma rate (RAKR) reported on a certificate from the Physikalisch-Technische Bundesanstalt (Berlin, Germany) (PTB) primary laboratory and the SK determined at the University of Wisconsin Madison Radiation Research Center (UWMRRC)...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102948/use-of-parallel-plate-ionization-chambers-in-reference-dosimetry-of-novac-and-liac-%C3%A2-mobile-electron-linear-accelerators-for-intraoperative-radiotherapy-a-multi-center-survey
#15
Paolo Scalchi, Alessia Ciccotelli, Giuseppe Felici, Assunta Petrucci, Raffaella Massafra, Valeria Piazzi, Paola D'Avenia, Francesca Cavagnetto, Federica Cattani, Raffaella Romagnoli, Antonella Soriani
PURPOSE: LIAC(®) and NOVAC are two mobile linear accelerators dedicated to intraoperative radiation therapy (IORT), generating electron beams in the energy range of 3-12 MeV. Due to high dose-per-pulse (up to 70 mGy per pulse), in 2003 the Italian National Institute of Health (ISS) stated that "for the measure of dose to water in reference conditions, ionization chambers cannot be employed and no published dosimetry protocol can be used". As a consequence, ferrous sulphate (or, alternatively alanine) dosimetry was recommended...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102946/a-portal-dosimetry-dose-prediction-method-based-on-collapsed-cone-algorithm-using-the-clinical-beam-model
#16
J Martínez Ortega, N Gómez González, P Castro Tejero, M Pinto Monedero, N B Tolani, L Núñez Martín, R Sánchez Montero
PURPOSE: Amorphous silicon electronical portal imaging devices (EPIDs) are widely used for dosimetric measurements in Radiation Therapy. The purpose of this work was to determine if a portal dose prediction method can be utilized for dose map calculations based on the linear accelerator model within a commercial treatment planning system (Pinnacle(3) v8.0 m). METHODS: The method was developed for a 6 MV photon beam on the Varian Clinac 21-EX, at a nominal dose rate of 400 MU/min...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102944/a-simple-and-robust-trajectory-based-stereotactic-radiosurgery-treatment
#17
Byron Wilson, Karl Otto, Ermias Gete
INTRODUCTION: We present a Trajectory-based Volumetric Modulated Arc Therapy (TVMAT) technique for Stereotactic Radiosurgery (SRS) that takes advantage of a modern linacs ability to modulate dose rate and move the couch dynamically. In addition, we investigate the quality of the developed TVMAT method and the dosimetric accuracy of the technique. METHODS: The main feature of the TVMAT technique is a standard beam trajectory formed by dynamic motion of the treatment couch and the linac gantry...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102943/comparison-of-five-cluster-validity-indices-performance-in-brain-18-f-fet-pet-image-segmentation-using-k-means
#18
Bedor Abualhaj, Guoyang Weng, Melissa Ong, Ali Asgar Attarwala, Flavia Molina, Karen Büsing, Gerhard Glatting
PURPOSE: Dynamic [(18) F]fluoro-ethyl-L-tyrosine positron emission tomography ([(18) F]FET-PET) is used to identify tumor lesions for radiotherapy treatment planning, to differentiate glioma recurrence from radiation necrosis and to classify gliomas grading. To segment different regions in the brain k-means cluster analysis can be used. The main disadvantage of k-means is that the number of clusters must be pre-defined. In this study, we therefore compared different cluster validity indices for automated and reproducible determination of the optimal number of clusters based on the dynamic PET data...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28102933/what-if-a-tumor-is-significantly-enlarged-just-before-stereotactic-body-radiation-therapy-a-case-report-and-review-of-the-literature
#19
Hung-Jen Chen, Ji-An Liang, Chih-Yi Chen, Yang-Hao Yu, Chun-Ru Chien
Stereotactic body radiation therapy (SBRT) plays an important role in early stage non-small cell lung cancer. Tumor growth before radiotherapy planning (RTP) or during SBRT has been reported in lung cancer patients; however, little is known of growth during the period in-between (i.e. after RTP but before SBRT). An 83-year-old man referred to our hospital and diagnosed with medically inoperable non-small cell lung cancer was noted to have significant tumor progression on day 1 of cone beam computed tomography just before the planned SBRT delivery...
November 18, 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/28102829/absorbed-dose-evaluation-of-auger-electron-emitting-radionuclides-impact-of-input-decay-spectra-on-dose-point-kernels-and-s-values
#20
Nadia Falzone, Boon Lee, José Fernández-Varea, Christiana Kartsonaki, Andrew Stuchbery, Tibor Kibedi, Katherine Vallis
AIM: The aim of this study was to investigate the impact of decay data provided by the newly developed stochastic atomic relaxation model <i>BrIccEmis</i> on dose point kernels (DPKs- radial dose distribution around a unit point source) and <i>S</i>-values (absorbed dose per unit cumulated activity) of 14 Auger electron (AE) emitting radionuclides, namely <sup>67</sup>Ga, <sup>80m</sup>Br, <sup>89</sup>Zr, <sup>90</sup>Nb, <sup>99m</sup>Tc, <sup>111</sup>In, <sup>117m</sup>Sn, <sup>119</sup>Sb, <sup>123</sup>I, <sup>124</sup>I, <sup>125</sup>I, <sup>135</sup>La, <sup>195m</sup>Pt and <sup>201</sup>Tl...
January 19, 2017: Physics in Medicine and Biology
keyword
keyword
1207
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"