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Kate Ablett, Andrew R Thompson
Childhood skin conditions can affect the quality of life of children, adolescents, and families. As such, paediatric dermatological conditions have been the focus of a number of qualitative studies and there is now a need to integrate the findings. A meta-ethnography was carried out with the existing 12 studies, which included nine studies examining parental experiences and three studies of child experiences. Meta-ethnographic analysis of the studies identified themes focused on the child's sense of stigmatisation and the challenges for families that arose from this...
October 18, 2016: Body Image
Samuele Zilioli, Ledina Imami, Richard B Slatcher
Social class is a robust predictor of health, with risk for disease and mortality increasing towards the lower end of the socioeconomic (SES) spectrum. While certain psychological characteristics, such as high sense of control, can protect low-SES individuals from adverse health outcomes, very few studies have investigated the biological mechanisms underlying these relationships. In this study, we tested whether sense of control mitigated the associations between SES and cortisol activity, and SES and physical health in daily life (i...
October 6, 2016: Psychoneuroendocrinology
Alexandre Caron, Denis Richard
With the still-growing prevalence of obesity worldwide, major efforts are made to understand the various behavioral, environmental, and genetic factors that promote excess fat gain. Obesity results from an imbalance between energy intake and energy expenditure, which emphasizes the importance of deciphering the mechanisms behind energy balance regulation to understand its physiopathology. The control of energy balance is assured by brain systems/circuits capable of generating adequate ingestive and thermogenic responses to maintain the stability of energy reserves, which implies a proper integration of the homeostatic signals that inform about the status of the energy stores...
October 21, 2016: Annals of the New York Academy of Sciences
Salma Al-Karmi, Silvia A Albu, Alyssa Vito, Nancy Janzen, Shannon Czorny, Laura Banevicius, Max Nanao, Jon Zubieta, Alfredo Capretta, John F Valliant
Hydrocyanine dyes are sensitive "turn-on" type optical probes that can detect reactive oxygen species (ROS). We have developed a method to prepare an 18F-labeled hydrocyanine dye as a multi-modal PET and optical "turn-on" probe. A commercially available NIR dye was modified with a fluorinated prosthetic group that did not alter its ROS sensing properites in the presence of superoxide and hydroxyl radicals. The 18F-labeled analogue was produced using a single step terminal fluorination procedure. PET imaging and quantitative in vivo biodistribution studies indicated this novel probe had remarkably different pharmacokinetics compared to the oxidized cyanine analogue...
October 21, 2016: Chemistry: a European Journal
Hung-Wei Yang, Rung-Ywan Tsai, Jung-Po Chen, Shin-Pon Ju, Jing-Fong Liao, KuoChen Wei, Wei-Lun Zou, Mu-Yi Hua
A simple and accurate device for early detection of malignancies is paramount for prompt treatment and prevention of metastases. In this study, we describe a novel fabrication method for producing an ordered nano-gold-dot array with strong localized surface plasmon resonance (LSPR) and narrow bandwidth. The array was used as an optical bio-sensing chip for the detection of vascular endothelial growth factor (VEGF) in human serum. The biochip was constructed by conjugating an anti-VEGF antibody, a specific bio-recognition element for VEGF, onto the array via the fragment crystallizable (Fc) region of the antibody, ultimately increasing the efficiency of VEGF detection...
October 21, 2016: ACS Applied Materials & Interfaces
Amanda M West, Paul H Evangelista, Catherine S Jarnevich, Nicholas E Young, Thomas J Stohlgren, Colin Talbert, Marian Talbert, Jeffrey Morisette, Ryan Anderson
Early detection of invasive plant species is vital for the management of natural resources and protection of ecosystem processes. The use of satellite remote sensing for mapping the distribution of invasive plants is becoming more common, however conventional imaging software and classification methods have been shown to be unreliable. In this study, we test and evaluate the use of five species distribution model techniques fit with satellite remote sensing data to map invasive tamarisk (Tamarix spp.) along the Arkansas River in Southeastern Colorado...
October 11, 2016: Journal of Visualized Experiments: JoVE
Brun Jean-Frédéric, Boulot Pierre, Varlet-Marie Emmanuelle
Physiological studies on fetal blood in narrow glass tubes have suggested that fetal optimal hematocrit (hct) might be as high as 60%. A theoretical 'ideal' hct can also be predicted with a theoretical curve of hematocrit/viscosity (h/η) ratio vs hct constructed with Quemada's model. We used the database of one of our previous papers on fetal hemorheology to reinterpret its results with this concept. A series of 28 intrauterine cord punctures (between 19 and 33 weeks gestation) with doppler measurements of resistance in umbilical arteries was studied...
October 18, 2016: Clinical Hemorheology and Microcirculation
Virginia Ginny Stoffel
Family is a metaphor for the connectedness that occupational therapy practitioners and students feel for one another, for the American Occupational Therapy Association (AOTA), and toward those served. Exploring values and cultural practices that emanate from family experiences affects how we practice occupational therapy and engage with families; how we serve and lead; and how, as the profession approaches its 100th anniversary in the United States, we strengthen AOTA by welcoming all 213,000 practitioners and students who could become active, engaged members...
November 2016: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
Xiu-Zhi Wu, Qiong Zhou, Hua Lin, Kan Zhai, Xiao-Juan Wang, Wei-Bing Yang, Huan-Zhong Shi
RATIONALE: Toll like receptor (TLR) 2 is well known by sensing multiple ligands; however, its role in the development of malignant pleural effusion (MPE) remains unknown. We performed the present study to explore the impact of TLR2 signaling on the development of MPE, and to define the underline mechanisms by which TLR2 works. METHODS: Development of MPE was compared between TLR2-/- and wild type (WT) mice. The effect of TLR2 on differentiation of Th17, Th9, and Th2 cells in MPE was explored...
October 21, 2016: American Journal of Respiratory Cell and Molecular Biology
Nathaniel Andrew, Suzanne Meeks
OBJECTIVES: Person-centered care constructs such as fulfilled preferences, sense of control, and life satisfaction might contribute to loneliness among nursing home residents, but these relationships have not been thoroughly explored. The aim of this study was to examine the relationship between fulfilled preferences and loneliness in nursing home residents with perceived control and life satisfaction as potential mediators. METHODS: The study utilized a cross-sectional design, examining the targeted variables with a questionnaire administered by trained research staff...
October 21, 2016: Aging & Mental Health
A S M Iftekhar Uddin, Usman Yaqoob, Gwiy-Sang Chung
Herein we report an enhanced triboelectric nanogenerator (TENG) based on the contact-separation mode between a patterned film of polydimethylsiloxane (PDMS) with a semi-metallic elastomer of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) and a nylon fiber film. The addition of ethylene glycol to the PEDOT:PSS film improves the functionality of the TENG significantly, yielding promising applicability in both indoor and outdoor (i.e., under sunlight) environments, with the maximum instantaneous power of 0...
October 21, 2016: ACS Applied Materials & Interfaces
Hao Zhu, Jiangli Fan, Huiying Mu, Tao Zhu, Zhen Zhang, Jianjun Du, Xiaojun Peng
Polarity-sensitive fluorescent probes are powerful chemical tools for studying biomolecular structures and activities both in vitro and in vivo. However, the lack of "off-on" polarity-sensing probes has limited the accurate monitoring of biological processes that involve an increase in local hydrophilicity. Here, we design and synthesize a series of "off-on" polarity-sensitive fluorescent probes BP series consisting of the difluoroboron dippyomethene (BODIPY) fluorophore connected to a quaternary ammonium moiety via different carbon linkers...
October 21, 2016: Scientific Reports
Mona Agel
Data sourcesPubMed, Embase, Ebsco/PsycInfo, Ebsco/CINAHL and ISI/Web of Science databases.Study selectionStudies that evaluated the association between the psychosocial correlates and oral hygiene behaviour varying from self-reports to clinical measurements, including plaque and bleeding scores were considered.Data extraction and synthesisTwo reviewers independently selected studies, abstracted data and assessed study quality using a modified version of the Newcastle-Ottawa Scale.ResultsTwenty-four studies were included providing 31 datasets...
September 2016: Evidence-based Dentistry
Li-Wa Shao, Rong Niu, Ying Liu
Neurons have a central role in the systemic coordination of mitochondrial unfolded protein response (UPR(mt)) and the cell non-autonomous modulation of longevity. However, the mechanism by which the nervous system senses mitochondrial stress and communicates to the distal tissues to induce UPR(mt) remains unclear. Here we employ the tissue-specific CRISPR-Cas9 approach to disrupt mitochondrial function only in the nervous system of Caenorhabditis elegans, and reveal a cell non-autonomous induction of UPR(mt) in peripheral cells...
October 21, 2016: Cell Research
Thomas Voets
Two recent studies reveal a crucial role for the cation channel TRPM2 in sensing warm temperatures, both in the thermoregulatory center of the brain and in the somatosensory system.
October 21, 2016: Cell Research
Matthieu O Pasquet, Matthieu Tihy, Aurélie Gourgeon, Marco N Pompili, Bill P Godsil, Clément Léna, Guillaume P Dugué
While miniature inertial sensors offer a promising means for precisely detecting, quantifying and classifying animal behaviors, versatile inertial sensing devices adapted for small, freely-moving laboratory animals are still lacking. We developed a standalone and cost-effective platform for performing high-rate wireless inertial measurements of head movements in rats. Our system is designed to enable real-time bidirectional communication between the headborne inertial sensing device and third party systems, which can be used for precise data timestamping and low-latency motion-triggered applications...
October 21, 2016: Scientific Reports
Wei Lv, Asegun Henry
Thermal conductivity is important for almost all applications involving heat transfer. The theory and modeling of crystalline materials is in some sense a solved problem, where one can now calculate their thermal conductivity from first principles using expressions based on the phonon gas model (PGM). However, modeling of amorphous materials still has many open questions, because the PGM itself becomes questionable when one cannot rigorously define the phonon velocities. In this report, we used our recently developed Green-Kubo modal analysis (GKMA) method to study amorphous silicon dioxide (a-SiO2)...
October 21, 2016: Scientific Reports
S Drijkoningen, S D Janssens, P Pobedinskas, S Koizumi, M K Van Bael, K Haenen
Nanocrystalline diamond (NCD) membranes are promising candidates for use as sensitive pressure sensors. NCD membranes are able to withstand harsh conditions and are easily fabricated on glass. In this study the sensitivity of heavily boron doped NCD (B:NCD) pressure sensors is evaluated with respect to different types of supporting glass substrates, doping levels and membrane sizes. Higher pressure sensing sensitivities are obtained for membranes on Corning Eagle 2000 glass, which have a better match in thermal expansion coefficient with diamond compared to those on Schott AF45 glass...
October 21, 2016: Scientific Reports
Zhimin Xie, Dongliang Chai, Youshan Wang, Huifeng Tan
The effective potentials are of great importance for the coarse-grained (CG) simulations, which can be obtained by the structure-based iterative Boltzmann inversion (IBI) method. However, the standard IBI method is incapable of keeping the mechanical and thermodynamic properties of the CG model in consistence with those of the all-atom model. Unlike the existed techniques, such as introducing the friction force as the dissipative force to drop the superatom motion while the conservative force arising from the CG potential was kept intact, we directly modified the standard IBI nonbonded potential by adding an empirical function...
October 21, 2016: Journal of Physical Chemistry. B
Yang Jie, Huarui Zhu, Xia Cao, Yue Zhang, Ning Wang, Liqun Zhang, Zhong Lin Wang
Tactile sensing is of great importance in developing human-machine interface, remote control and security systems. Here, a self-triggered alarm system based on the one-piece triboelectric nanosensor (TENS) is reported. By using nitrocellulose (NC) membrane as the triboelectric material, the as-designed TENS can not only sensitively respond to physical contacts in a self-triggered mode, but also securely detect the third-level details of latent fingerprint. The self-triggered idea based on the triboelectric nanogenerator is compatible with intelligent interactive interface...
October 21, 2016: ACS Nano
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