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Meteor study

Sytske Anne Bergstra, Pedro M M C Machado, Rosaline van den Berg, Robert B M Landewé, Tom W J Huizinga
OBJECTIVES: Ten years ago, the METEOR tool was developed to simulate treatment-to-target and create an international research database. The development of the METEOR tool and database, research opportunities and future perspectives are described. METHODS: The METEOR tool is a free, online, internationally available tool in which daily practice visits of all rheumatoid arthritis patients visiting a rheumatologist can be registered. In the tool, disease characteristics, patient- and physician-reported outcomes and prescribed treatment could be entered...
September 2016: Clinical and Experimental Rheumatology
Martina Burnik Šturm, Oyunsaikhan Ganbaatar, Christian C Voigt, Petra Kaczensky
For certain remote areas like Mongolia, field-based precipitation, surface and ground water isotopic data are scarce. So far no such data exist for the Mongolian Gobi desert, which hinders the understanding of isotopic fractionation processes in this extreme, arid region. We collected 26 event-based precipitation samples, 39 Bij river samples, and 75 samples from other water bodies in the Dzungarian Gobi in SW Mongolia over a period of 16 months for hydrogen and oxygen stable isotope analysis. δ(2)H and δ(18)O values in precipitation show high seasonal variation and cover an extreme range: 175 ‰ for δ(2)H and 24 ‰ for δ(18)O values...
October 12, 2016: Isotopes in Environmental and Health Studies
John M C Plane, Juan Carlos Gómez-Martín, Wuhu Feng, Diego Janches
Silicon is one of the most abundant elements in cosmic dust, and meteoric ablation injects a significant amount of Si into the atmosphere above 80 km. In this study, a new model for silicon chemistry in the mesosphere/lower thermosphere is described, based on recent laboratory kinetic studies of Si, SiO, SiO2, and Si(+). Electronic structure calculations and statistical rate theory are used to show that the likely fate of SiO2 is a two-step hydration to silicic acid (Si(OH)4), which then polymerizes with metal oxides and hydroxides to form meteoric smoke particles...
April 16, 2016: Journal of Geophysical Research. Atmospheres: JGR
D Janches, J M C Plane, D Nesvorný, W Feng, D Vokrouhlický, M J Nicolls
Recent model development of the Zodiacal Dust Cloud (ZDC) model (Nesvorný et al. 2010, 2011b) argue that the incoming flux of meteoric material into the Earth's upper atmosphere is mostly undetected by radars because they cannot detect small extraterrestrial particles entering the atmosphere at low velocities due to the relatively small production of electrons. In this paper we present a new methodology utilizing meteor head echo radar observations that aims to constrain the ZDC physical model by ground-based measurements...
November 20, 2014: Astrophysical Journal
Adrián Ortega-Guerrero
High arsenic concentrations in groundwater have been documented in La Laguna Region (LLR) in arid northern Mexico, where arsenic poisoning is both chronic and endemic. A heated debate has continued for decades on its origin. LLR consisted of a series of ancient connected lakes that developed at the end of a topographic depression under closed basin conditions. This study addresses the isotopic, chemical composition of the groundwater and geochemical modeling in the southeasternmost part of the LLR to determine the origin of arsenic...
August 18, 2016: Environmental Geochemistry and Health
Alaa Ahmed, Ian Clark
The chemical characteristics of water in the Oratunga Area, Central Flinders Ranges, South Australia have been used to evaluate and determine the processes controlling water chemistry in addition to the sources of ions. The isotopic analysis results show that the groundwater is mainly meteoric. Based on the rock and water chemistry, ionic ratios, hydrochemical facies and saturation indices, the chemical evolution has been studied. The chemistry of groundwater revealed two types of water. Thus, in high topographic areas, low TDS, bicarbonate and mixed water types are dominated and support a rapid and direct recharge...
August 8, 2016: Science of the Total Environment
Philip N Judson, Anthony Long, Ernest Murray, Mukesh Patel
A previous paper1 described new metrics, veracity and utility, for assessing the performance of toxicity prediction systems that report confidence in their predictions. Assessing the performance of systems that predict mammalian metabolism is complicated by the absence of comprehensive sets of negative observations and predictions. This paper presents an approach to assessing the performance of such systems using veracity and utility.
May 2015: Molecular Informatics
E C M Dawkins, J M C Plane, M P Chipperfield, W Feng
The meteoric metal layers act as unique tracers of chemistry and dynamics in the upper atmosphere. Existing lidar studies from a few locations show that K exhibits a semiannual seasonality (winter and summer maxima), quite unlike the annual seasonality (winter maximum and summer minimum) seen with Na and Fe. This work uses spaceborne observations made with the Optical Spectrograph and InfraRed Imager System instrument on the Odin satellite to retrieve the near-global K layer for the first time. The satellite data (2004 to mid-2013) are used to validate the implementation of a recently proposed potassium chemistry scheme in a whole atmosphere chemistry climate model, which provides a chemical basis for this semiannual seasonal behavior...
August 16, 2015: Journal of Geophysical Research. Atmospheres: JGR
J D Carrillo-Sánchez, J M C Plane, W Feng, D Nesvorný, D Janches
The size and velocity distribution of cosmic dust particles entering the Earth's atmosphere is uncertain. Here we show that the relative concentrations of metal atoms in the upper mesosphere, and the surface accretion rate of cosmic spherules, provide sensitive probes of this distribution. Three cosmic dust models are selected as case studies: two are astronomical models, the first constrained by infrared observations of the Zodiacal Dust Cloud and the second by radar observations of meteor head echoes; the third model is based on measurements made with a spaceborne dust detector...
August 16, 2015: Geophysical Research Letters
Abraham E Springer, Elizabeth M Boldt, Katie M Junghans
The recharge location for many springs is unknown because they can be sourced from proximal, shallow, atmospheric sources or long-traveled, deep, regional aquifers. The stable isotope ((18) O and (2) H) geochemistry of springs water can provide cost-effective indications of relative flow path distance without the expense of drilling boreholes, conducting geophysical studies, or building groundwater flow models. Locally sourced springs generally have an isotopic signature similar to local precipitation for that region and elevation...
July 20, 2016: Ground Water
Yetsa A Tuakli-Wosornu, Faith Selzer, Elena Losina, Jeffrey N Katz
OBJECTIVE: To identify predictors of poor exercise adherence in patients with osteoarthritis (OA) and meniscal tear. DESIGN: Secondary analysis of data gathered over the first 12 weeks in the Meniscal Tear in Osteoarthritis Research (MeTeOR) Trial, a multicenter, randomized controlled trial. SETTING: Seven referral centers in the US. PARTICIPANTS: This analysis was conducted in 325 of the 351 MeTeOR patients, each of whom was ≥ 45 years old and had meniscal tear and osteoarthritic changes on imaging studies; 26 were excluded due to missing data from which to derive the primary outcome variable...
June 10, 2016: Archives of Physical Medicine and Rehabilitation
Toni K Choueiri, Bernard Escudier, Thomas Powles, Nizar M Tannir, Paul N Mainwaring, Brian I Rini, Hans J Hammers, Frede Donskov, Bruce J Roth, Katriina Peltola, Jae Lyun Lee, Daniel Y C Heng, Manuela Schmidinger, Neeraj Agarwal, Cora N Sternberg, David F McDermott, Dana T Aftab, Colin Hessel, Christian Scheffold, Gisela Schwab, Thomas E Hutson, Sumanta Pal, Robert J Motzer
BACKGROUND: Cabozantinib is an oral inhibitor of tyrosine kinases including MET, VEGFR, and AXL. The randomised phase 3 METEOR trial compared the efficacy and safety of cabozantinib versus the mTOR inhibitor everolimus in patients with advanced renal cell carcinoma who progressed after previous VEGFR tyrosine-kinase inhibitor treatment. Here, we report the final overall survival results from this study based on an unplanned second interim analysis. METHODS: In this open-label, randomised phase 3 trial, we randomly assigned (1:1) patients aged 18 years and older with advanced or metastatic clear-cell renal cell carcinoma, measurable disease, and previous treatment with one or more VEGFR tyrosine-kinase inhibitors to receive 60 mg cabozantinib once a day or 10 mg everolimus once a day...
July 2016: Lancet Oncology
Marco Domenicali, Manuel Tufoni, Vittoria Bevilacqua, Barbara Benazzi, Carmen Serena Ricci, Alessandra Tovoli, Lucia Napoli, Paolo Caraceni, Mauro Bernardi
PURPOSE: To identify dorsal acoustic windows (DAWs) for the study of the liver and to investigate whether they could improve the visualization of the liver in patients with chronic liver disease and ascites, meteorism, and/or obesity. METHODS: The study was based on a single ultrasound examination and divided into three successive stages. Firstly, we performed a preliminary study involving 10 cirrhotic patients to identify new DAWs. Inter-observer reproducibility of measurements obtained through the DAWs was then assessed in another 29 cirrhotic patients...
October 2013: Journal of Medical Ultrasonics
Ibraheem Hamdan, Bettina Wiegand, Mathias Toll, Martin Sauter
The Tanour spring is one of the several karst springs located in the northern part of Jordan. Water samples from the Tanour spring and precipitation were collected in the area of Ajloun in NW Jordan for the analysis of stable oxygen and hydrogen isotopes to evaluate the spring response to precipitation events. Rainwater and snow samples were collected from different elevations during winters of 2013-2014 and 2014-2015. In addition, spring samples were collected between December 2014 and March 2015. δ(18)O values in rainwater vary from -3...
December 2016: Isotopes in Environmental and Health Studies
Anna Totterdill, J C Gómez Martín, Tamás Kovács, Wuhu Feng, John M C Plane
No abstract text is available yet for this article.
June 2, 2016: Journal of Physical Chemistry. A
Isabella C C von Holstein, Cheryl A Makarewicz
RATIONALE: Light stable isotopic analysis of herbivore proteinaceous tissues (hair, muscle, milk) is critical for authenticating the point of origin of finished agricultural or industrial products in both ancient and modern economies. This study examined the distribution of light stable isotopes in herbivores in northern Europe (Iceland to Finland), which is expected to depend on regional-level environmental inputs (precipitation, temperature) and local variables (vegetation type, fodder type, soil type)...
June 30, 2016: Rapid Communications in Mass Spectrometry: RCM
Kudzai Farai Kaseke, Lixin Wang, Heike Wanke, Veronika Turewicz, Paul Koeniger
Global precipitation isoscapes based on the Global Network for Isotopes in Precipitation (GNIP) network are an important toolset that aid our understanding of global hydrologic cycles. Although the GNIP database is instrumental in developing global isoscapes, data coverage in some regions of hydrological interest (e.g., drylands) is low or non-existent thus the accuracy and relevance of global isoscapes to these regions is debatable. Capitalizing on existing literature isotope data, we generated rainfall isoscapes for Namibia (dryland) using the cokriging method and compared it to a globally fitted isoscape (GFI) downscaled to country level...
2016: PloS One
Chao Tian, Ping Meng, Jin-song Zhang, Shou-jia Sun, Chun-xia He, Chang-rong Jia, Jian-zhong Li
The seasonal characteristics of δD and δ¹⁸O in precipitation and the influence factors were studied in the Xiaolangdi Reservoir area at the eastern monsoon region of China. The precipitation samples and the corresponding meteorological data were collected between April and October from the year 2011 to 2014. The local meteoric water lines (LMWL) of different seasons were established, and the water vapor sources in different seasons were investigated. The results showed that the δD and δ¹⁸O in precipitation exhibited an extremely wide range and a distinct seasonal variation, and they were enriched in the spring, and depleted in the fall...
December 2015: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
Valerie Hubalek, Xiaofen Wu, Alexander Eiler, Moritz Buck, Christine Heim, Mark Dopson, Stefan Bertilsson, Danny Ionescu
Little research has been conducted on microbial diversity deep under the Earth's surface. In this study, the microbial communities of three deep terrestrial subsurface aquifers were investigated. Temporal community data over 6 years revealed that the phylogenetic structure and community dynamics were highly dependent on the degree of isolation from the earth surface biomes. The microbial community at the shallow site was the most dynamic and was dominated by the sulfur-oxidizing genera Sulfurovum or Sulfurimonas at all-time points...
October 2016: ISME Journal
Nina Rman
The aim of the study was to develop and test an optimal and cost-effective regional quality monitoring system in depleted transboundary low-temperature Neogene geothermal aquifers in the west Pannonian basin. Potential tracers for identification of seasonal and long-term quality changes of the Pleistocene thermal waters were investigated at four multiple-screened wells some 720 to 1570 m deep in Slovenia. These thermal waters are of great balneological value owing to their curative effects and were sampled monthly between February 2014 and January 2015...
April 2016: Environmental Monitoring and Assessment
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