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cardiac arrhythmia interpretation

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https://www.readbyqxmd.com/read/27909501/-two-for-the-price-of-one-a-single-lead-implantable-cardioverter-defibrillator-system-with-a-floating-atrial-dipole
#1
REVIEW
Nicole E Worden Md, Musab Alqasrawi Md, Siva M Krothapalli Md, Alexander Mazur Md
In patients known to be a high risk for sudden cardiac arrest, implantable cardioverter defibrillators (ICD) are a proven therapy to reduce risk of death. However, in patients without conventional indications for pacing, the optimal strategy for type of device, dual- versus single-chamber, remains debatable. The benefit of prophylactic pacing in this category of patients has never been documented. Although available atrial electrograms in a dual chamber system improve interpretation of stored arrhythmia events, allow monitoring of atrial fibrillation and may potentially reduce the risk of inappropriate shocks by enhancing automated arrhythmia discrimination, the use of dual-chamber ICDs has a number of disadvantages...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27908173/pacemaker-and-icd-oversensing-induced-by-movements-near-the-mri-scanner-bore
#2
E Mattei, F Censi, G Calcagnini, R Falsaperla, E Genovese, A Napolitano, V Cannatà
PURPOSE: The effect of the movement near the MRI scanner bore for people with a pacemaker (PM) or an implantable cardioverter defibrillator (ICD) is experimentally evaluated and discussed. METHODS: The authors performed in vitro measurements on a saline-filled human-shaped phantom (male, 170 cm height), equipped first with an MR-conditional PM (bicameral configuration, DDD programming), then with an MR-conditional ICD (biventricular configuration, detection algorithms enable but shock delivery disable)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27894294/appropriate-threshold-levels-of-cardiac-beat-to-beat-variation-in-semi-automatic-analysis-of-equine-ecg-recordings
#3
Mette Flethøj, Jørgen K Kanters, Philip J Pedersen, Maria M Haugaard, Helena Carstensen, Lisbeth H Olsen, Rikke Buhl
BACKGROUND: Although premature beats are a matter of concern in horses, the interpretation of equine ECG recordings is complicated by a lack of standardized analysis criteria and a limited knowledge of the normal beat-to-beat variation of equine cardiac rhythm. The purpose of this study was to determine the appropriate threshold levels of maximum acceptable deviation of RR intervals in equine ECG analysis, and to evaluate a novel two-step timing algorithm by quantifying the frequency of arrhythmias in a cohort of healthy adult endurance horses...
November 28, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27879323/issues-and-challenges-in-diagnostic-sequencing-for-inherited-cardiac-conditions
#4
REVIEW
Roddy Walsh, Stuart A Cook
BACKGROUND: Inherited cardiac conditions are a relatively common group of Mendelian diseases associated with ill health and death, often in the young. Research into the genetic causes of these conditions has enabled confirmatory and predictive diagnostic sequencing to become an integral part of the clinical management of inherited cardiomyopathies, arrhythmias, aortopathies, and dyslipidemias. CONTENT: Currently, the principle benefit of clinical genetic testing is the cascade screening of family members of patients with a pathogenic variant, enabling targeted follow up of presymptomatic genotype-positive individuals and discharge of genotype-negative individuals to health...
November 22, 2016: Clinical Chemistry
https://www.readbyqxmd.com/read/27871122/efficacy-and-safety-of-ablation-for-people-with-non-paroxysmal-atrial-fibrillation
#5
REVIEW
Jonathan Nyong, Guy Amit, Alma J Adler, Onikepe O Owolabi, Pablo Perel, David Prieto-Merino, Pier Lambiase, Juan Pablo Casas, Carlos A Morillo
BACKGROUND: The optimal rhythm management strategy for people with non-paroxysmal (persistent or long-standing persistent) atrial fibrilation is currently not well defined. Antiarrhythmic drugs have been the mainstay of therapy. But recently, in people who have not responded to antiarrhythmic drugs, the use of ablation (catheter and surgical) has emerged as an alternative to maintain sinus rhythm to avoid long-term atrial fibrillation complications. However, evidence from randomised trials about the efficacy and safety of ablation in non-paroxysmal atrial fibrillation is limited...
November 22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27867423/marginalized-zero-altered-models-for-longitudinal-count-data
#6
Loni Philip Tabb, Eric J Tchetgen Tchetgen, Greg A Wellenius, Brent A Coull
Count data often exhibit more zeros than predicted by common count distributions like the Poisson or negative binomial. In recent years, there has been considerable interest in methods for analyzing zero-inflated count data in longitudinal or other correlated data settings. A common approach has been to extend zero-inflated Poisson models to include random effects that account for correlation among observations. However, these models have been shown to have a few drawbacks, including interpretability of regression coefficients and numerical instability of fitting algorithms even when the data arise from the assumed model...
October 2016: Statistics in Biosciences
https://www.readbyqxmd.com/read/27837002/safety-of-domperidone-in-treating-nausea-associated-with-dihydroergotamine-infusion-and-headache
#7
Nathaniel M Robbins, Hiroyuki Ito, Melvin M Scheinman, Peter J Goadsby
OBJECTIVE: To determine the safety of domperidone in the treatment of nausea associated with dihydroergotamine (DHE) infusion and headache. METHODS: We audited our use of domperidone for the inpatient management of nausea, focusing on known safety concerns, particularly potential cardiac arrhythmias. RESULTS: We reviewed 103 consecutive admissions of 90 patients admitted for IV DHE by infusion. Most admissions were to treat chronic migraine with (n = 53) or without (n = 46) aura...
November 11, 2016: Neurology
https://www.readbyqxmd.com/read/27832567/comparison-of-bioreactance-non-invasive-cardiac-output-measurements-with-cardiac-magnetic-resonance-imaging
#8
F Trinkmann, C Schneider, J D Michels, K Stach, C Doesch, S O Schoenberg, M Borggrefe, J Saur, T Papavassiliu
Impedance cardiography measurement of cardiac output gained wide interest due to its ease of use and non-invasiveness. However, validation studies of different algorithms yielded diverging results. Bioreactance (BR) as a recent adaption differs fundamentally as the flow signal is derived from phase shifts. Our aim was to assess the accuracy and reproducibility of BR, as compared to the non-invasive gold standard--cardiac magnetic resonance imaging (CMR). We prospectively included 32 stable patients. BR was performed twice in the supine position and averaged over 30 seconds...
November 2016: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/27773624/-validation-of-taking-arterial-pulse-in-primary-care-for-the-detection-of-atrial-fibrillation-and-other-cardiac-rhythm-disorders-in-patients-over-65-years-old
#9
L A Pérula-de Torres, V González-Blanco V, R Luque-Montilla, E Martín-Rioboó, M A Martínez-Adell, J Ruiz-de Castroviejo
INTRODUCTION: Atrial fibrillation (AF) is the most frequent arrhythmia in clinical practice and has important prognostic implications. The objective of this study was to demonstrate the validity and the reliability of taking the arterial pulse (TAP) in patients over 65 years for detecting in AF and other rhythm disorders. MATERIALS AND METHODS: A descriptive, observational, multicentre study to validate a diagnostic test within in a controlled clinical trial. SETTING: 39 Primary Care Centres in the Spanish National Health Service...
October 20, 2016: Semergen
https://www.readbyqxmd.com/read/27469897/using-the-think-aloud-technique-to-explore-quality-of-life-issues-during-standard-quality-of-life-questionnaires-in-patients-with-atrial-fibrillation
#10
Ling Zhang, Robyn Gallagher, Nicole Lowres, Jessica Orchard, S Ben Freedman, Lis Neubeck
AIMS AND OBJECTIVES: To investigate whether using the 'think aloud' technique during standard quality of life surveys provides useful additional information about patients' experiences of living with atrial fibrillation (AF) and health related quality of life (HRQoL). BACKGROUND: Atrial fibrillation is the most common cardiac arrhythmia and has serious health consequences, particularly ischaemic stroke, high rates of morbidity and mortality and poor HRQoL. Standard quality-of-life questionnaires are often used but may not provide sufficient detail of patients' experiences living with AF...
July 14, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27128800/hormones-and-sex-differences-changes-in-cardiac-electrophysiology-with-pregnancy
#11
REVIEW
Glenna C L Bett
Disruption of cardiac electrical activity resulting in palpitations and syncope is often an early symptom of pregnancy. Pregnancy is a time of dramatic and dynamic physiological and hormonal changes during which numerous demands are placed on the heart. These changes result in electrical remodelling which can be detected as changes in the electrocardiogram (ECG). This gestational remodelling is a very under-researched area. There are no systematic large studies powered to determine changes in the ECG from pre-pregnancy, through gestation, and into the postpartum period...
May 1, 2016: Clinical Science (1979-)
https://www.readbyqxmd.com/read/27124801/advanced-ecg-in-2016-is-there-more-than-just-a-tracing
#12
Tobias Reichlin, Roger Abächerli, Raphael Twerenbold, Michael Kühne, Beat Schaer, Christian Müller, Christian Sticherling, Stefan Osswald
The 12-lead electrocardiogram (ECG) is the most frequently used technology in clinical cardiology. It is critical for evidence-based management of patients with most cardiovascular conditions, including patients with acute myocardial infarction, suspected chronic cardiac ischaemia, cardiac arrhythmias, heart failure and implantable cardiac devices. In contrast to many other techniques in cardiology, the ECG is simple, small, mobile, universally available and cheap, and therefore particularly attractive. Standard ECG interpretation mainly relies on direct visual assessment...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27117817/behavioural-brain-and-cardiac-responses-to-hypobaric-hypoxia-in-broiler-chickens
#13
Jessica E Martin, Karen Christensen, Yvonne Vizzier-Thaxton, Malcolm A Mitchell, Dorothy E F McKeegan
A novel approach to pre-slaughter stunning of chickens has been developed in which birds are rendered unconscious by progressive hypobaric hypoxia. Termed Low Atmospheric Pressure Stunning (LAPS), this approach involves application of gradual decompression lasting 280s according to a prescribed curve. We examined responses to LAPS by recording behaviour, electroencephalogram (EEG) and electrocardiogram (ECG) in individual male chickens, and interpreted these with regard to the welfare impact of the process...
September 1, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/27080538/marine-omega-3-highly-unsaturated-fatty-acids-from-mechanisms-to-clinical-implications-in-heart-failure-and-arrhythmias
#14
REVIEW
Tobias Glück, Peter Alter
Therapeutic implications of marine omega-3 highly unsaturated fatty acids (HUFA) in cardiovascular disease are still discussed controversially. Several clinical trials report divergent findings and thus leave ambiguity on the meaning of oral omega-3 therapy. Potential prognostic indications of HUFA treatment have been predominantly studied in coronary artery disease, sudden cardiac death, ventricular arrhythmias, atrial fibrillation and heart failure of various origin. It is suspected that increased ventricular wall stress is crucially involved in the prognosis of heart failure...
July 2016: Vascular Pharmacology
https://www.readbyqxmd.com/read/27037505/the-prevalence-and-clinical-significance-of-premature-ventricular-beats-in-the-athlete
#15
F D'Ascenzi, A Zorzi, F Alvino, M Bonifazi, D Corrado, S Mondillo
Adolescents and adults with cardiovascular disease who are engaged in sports activity have an increased risk of sudden cardiac death (SCD) that is three times greater than that of their non-athletic counterparts. Sport acts as a trigger for cardiac arrest in the presence of underlying cardiovascular diseases predisposing to life-threatening ventricular arrhythmias. Frequent and complex premature ventricular beats (PVBs) detected during the cardiovascular screening of the athletic population may be a sign of an underlying cardiovascular disease at risk of SCD, but are also often recorded in trained athletes without cardiovascular abnormalities...
March 31, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/26943358/-hypersensitivity-reactions-to-implantable-cardiac-pacemakers-and-defibrillators
#16
REVIEW
B Kreft
Nowadays, for modern electrotherapy of cardiac arrhythmias different pacemaker systems are used. Antibradycardia pacing systems (e. g. single-chamber, two-chamber, three-chamber systems, frequency-adapted pacemaker) can be distinguished from antitachycardia pacing systems like implantable or portable cardioverter defibrillators and combined antibradycardia/antitachycardia systems. Cutaneous reactions overlying a pacemaker or defibrillator are often termed "pacemaker dermatitis". In terms of the differential diagnostic workup, these cutaneous reactions can have various causes...
May 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/26838316/cardiac-mechano-gated-ion-channels-and-arrhythmias
#17
REVIEW
Rémi Peyronnet, Jeanne M Nerbonne, Peter Kohl
Mechanical forces will have been omnipresent since the origin of life, and living organisms have evolved mechanisms to sense, interpret, and respond to mechanical stimuli. The cardiovascular system in general, and the heart in particular, is exposed to constantly changing mechanical signals, including stretch, compression, bending, and shear. The heart adjusts its performance to the mechanical environment, modifying electrical, mechanical, metabolic, and structural properties over a range of time scales. Many of the underlying regulatory processes are encoded intracardially and are, thus, maintained even in heart transplant recipients...
January 22, 2016: Circulation Research
https://www.readbyqxmd.com/read/26807261/risk-factors-and-clinical-outcomes-of-arrhythmias-in-the-medical-intensive-care-unit
#18
Rodrigo J Valderrábano, Alejandro Blanco, Eduardo J Santiago-Rodriguez, Christine Miranda, José Rivera-Del Rio Del Rio, Juan Ruiz, Robert Hunter
BACKGROUND: The clinical impact of arrhythmias on the continuum of critical illness is unclear, and data in medical intensive care units (ICU) is lacking. In this study, we distinguish between different types of arrhythmias and evaluate if their distinction is of clinical importance based on ICU length of stay and mortality outcomes. METHODS: We performed a retrospective analysis of 215 patients in a community-based teaching hospital medical ICU. Variables gathered include sociodemographic data, arrhythmias identified and interpreted by the study team, and admission diagnoses coded into clinical mediator categories based on theorized common risk pathways...
2016: Journal of Intensive Care
https://www.readbyqxmd.com/read/26803553/the-effect-of-conduction-velocity-slowing-in-left-ventricular-midwall-on-the-qrs-complex-morphology-a-simulation-study
#19
Ljuba Bacharova, Vavrinec Szathmary, Jana Svehlikova, Anton Mateasik, Julia Gyhagen, Milan Tysler
UNLABELLED: Midwall fibrosis is a frequent finding in different types of left ventricular hypertrophy. Fibrosis presents a local conduction block that can create a substrate for ventricular arrhythmias and lead to the continuous generation of reentry. Having also impact on the sequence of ventricular activation it can modify the shape of QRS complex. In this study we simulated the effects of slowed conduction velocity in the midwall in the left ventricle and in its anteroseptal region on the QRS morphology using a computer model...
March 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/26741332/on-the-usefulness-of-a-multilevel-logistic-regression-approach-to-person-fit-analysis
#20
Judith M Conijn, Wilco H M Emons, Marcel A L M van Assen, Klaas Sijtsma
The logistic person response function (PRF) models the probability of a correct response as a function of the item locations. Reise (2000) proposed to use the slope parameter of the logistic PRF as a person-fit measure. He reformulated the logistic PRF model as a multilevel logistic regression model and estimated the PRF parameters from this multilevel framework. An advantage of the multilevel framework is that it allows relating person fit to explanatory variables for person misfit/fit. We critically discuss Reise's approach...
April 11, 2011: Multivariate Behavioral Research
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