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https://www.readbyqxmd.com/read/27922286/central-pontine-myelinolysis-during-pregnancy-pathogenesis-diagnosis-and-management
#1
María Luisa Sánchez-Ferrer, María Teresa Prieto-Sánchez, Rodrigo Orozco-Fernández, Francisco Machado-Linde, Anibal Nieto-Diaz
Central pontine myelinolysis (CPM) is a rare condition usually caused by rapid sodium correction in hyponatraemia after a severe neurological syndrome. Only few cases have been reported during pregnancy, most of which were reported in patients with hyperemesis. We describe the successful management of the first case of twin pregnancy in a patient who presented with CPM after treatment for premature labour and then review the literature on CPM in pregnancy (aetiology, diagnosis and management). Our patient required emergency delivery to achieve electrolyte and fluid balance...
December 6, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27920706/ipilimumab-induced-enteritis-without-colitis-a-new-challenge
#2
Marcus Messmer, Sunita Upreti, Yaman Tarabishy, Nikhilesh Mazumder, Reezwana Chowdhury, Mark Yarchoan, Matthias Holdhoff
INTRODUCTION: Ipilimumab is an immune checkpoint inhibitor targeting cytotoxic T-lymphocyte associated antigen 4 (CTLA4), approved to treat metastatic melanoma. It was the first therapy shown to prolong survival in a large, randomized clinical trial. However, immune-related adverse events are common and can be severe. Enterocolitis is a common adverse event with ipilimumab, but enteritis without colitis has not been previously described. CASE REPORT: An 83-year-old man presented to our hospital with grade 3 diarrhea for 5 days...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27915351/the-role-of-nephrologist-in-the-intensive-care-unit
#3
Zoltán H Endre
Participation by nephrologists is needed in most intensive care units, even when such units are 'closed'. This participation should assist with diagnosis and management of intrinsic and complex renal diseases such as vasculitis, complex metabolic and electrolyte disorders including hyponatremia, and acute kidney injury (AKI) with and without underlying chronic kidney disease (CKD). Early nephrologist involvement will also facilitate transition to continuing care and follow-up after an episode of AKI, but may also assist in avoiding dialysis where treatment is futile...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915174/molecular-and-physiological-responses-of-iranian-perennial-ryegrass-as-affected-by-trinexapac-ethyl-paclobutrazol-and-abscisic-acid-under-drought-stress
#4
Mohammad Hossein Sheikh Mohammadi, Nematollah Etemadi, Mohammad Mehdi Arab, Mostafa Aalifar, Mostafa Arab, Mohammad Pessarakli
Drought stress is the major limiting factor which affects turfgrass management in area with restricted rainfall or irrigation water supply. Trinexapac ethyl (TE), Paclobutrazol (PAC) and Abscisic acid (ABA) are three plant growth regulators (PGRs) that are commonly used on turf species for increasing their tolerance to different environmental stresses such as drought. However, little is known about the impact of PGRs on stress tolerance of Iranian Perennial ryegrass (Lolium perenne). The present study was conducted to examine the visual and physiological changes of Iranian Perennial ryegrass in response to foliar application of TE, PAC, and ABA under drought stress conditions...
November 27, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27908485/managing-fluid-and-electrolyte-disorders-in-kidney-disease
#5
REVIEW
Cathy Langston
Because of the role of the kidneys in maintaining homeostasis in the body, kidney disease leads to derangements of fluid, electrolyte, and acid-base balance. The most effective therapy of a uremic crisis is careful management of fluid balance, which involves thoughtful assessment of hydration, a fluid treatment plan personalized for the specific patient, and repeated and frequent reassessment of fluid and electrolyte balance. Disorders of sodium, chloride, potassium, calcium, and phosphorus are commonly encountered in kidney disease and some may be life-threatening...
November 28, 2016: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/27893999/ebola-virus-disease-an-update-on-current-prevention-and-management-strategies
#6
REVIEW
M A Trad, W Naughton, A Yeung, L Mazlin, M O'sullivan, N Gilroy, D A Fisher, R L Stuart
Ebola virus disease (EVD) is characterised by systemic viral replication, immuno-suppression, abnormal inflammatory responses, large volume fluid and electrolyte losses, and high mortality in under-resourced settings. There are various therapeutic strategies targeting EVD including vaccines utilizing different antigen delivery methods, antibody-based therapies and antiviral drugs. These therapies remain experimental, but received attention following their use particularly in cases treated outside West Africa during the 2014-15 outbreak, in which 20 (80%) out of 25 patients survived...
November 11, 2016: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27889623/training-needs-of-clinical-nurses-at-an-university-hospital-in-turkey
#7
Emine Kol, Emine İlaslan, Mehtap Turkay
The learning needs of clinical nurses should be determined and evaluated at regular intervals for evaluate the continuity and the efficiency of education. The descriptive study was conducted to determine the training needs of nurses working in an educational hospital between February 1st 2012 and May 1st 2012. It was determined that, among the training topics related to patient care, those demanded the most were cardio-pulmonary resuscitation, fluid-electrolyte balance, safe drug administration and wound Care...
November 16, 2016: Nurse Education in Practice
https://www.readbyqxmd.com/read/27889509/ultrastructural-and-developmental-evidence-of-phytotoxicity-on-cos-lettuce-lactuca-sativa-associated-with-nonylphenol-exposure
#8
Willeke de Bruin, Chris van der Merwe, Quenton Kritzinger, Riana Bornman, Lise Korsten
It has long been understood that the presence of endocrine disrupter chemicals (EDCs) in water can affect the reproductive, behavioural and regulatory systems of different types of mammals. Thus far, only a handful of studies have examined its impact on plant systems. Present research is limited to the potential uptake of these chemicals by plants and the general phytotoxic effects it can elicit. The aim of this study was to determine what effect an EDC has on developing plant and cell organelles and how it affects it...
November 24, 2016: Chemosphere
https://www.readbyqxmd.com/read/27881286/renal-adaptive-changes-and-sodium-handling-in-the-fetal-to-newborn-transition
#9
REVIEW
Jeffrey L Segar
Appropriate fluid and electrolyte management is critical for optimal care of very low birth weight or sick infants. Delivery of such care requires an understanding of developmental changes in renal water and salt handling that occur with advancing gestational age as well as postnatal age. This review focuses on the principles of sodium homeostasis during fetal and postnatal life. The physiology of renal tubular transport mechanisms, as well as neurohumoral factors impacting renal tubular transport are highlighted...
November 20, 2016: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27875284/parenteral-nutrition-electrolyte-abnormalities-and-associated-factors-before-and-after-nutrition-support-team-initiation
#10
Katie Braun, Anne Utech, Maria Eugenia Velez, Renee Walker
BACKGROUND: Studied since the 1940s, refeeding syndrome still has no universal definition, thus making comparison of studies difficult. Negative outcomes (eg, metabolic abnormalities) may occur with the use of specialized nutrition, such as parenteral nutrition (PN). Less than half of medical institutions have a nutrition support team (NST) managing PN. Interdisciplinary team management of PN may reduce negative outcomes of PN. The objective of this study was to show the value of the NST by measuring differences in PN variables, especially electrolyte abnormalities (EAs), before and after NST initiation at a large medical center and to identify factors associated with EAs among adult subjects receiving PN...
October 18, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27871178/use-of-polyethylene-glycol-in-functional-constipation-and-fecal-impaction
#11
Miguel Mínguez, Antonio López Higueras, Javier Júdez
OBJECTIVE: The objective of this study was to evaluate in an analytical and descriptive manner the evidence published so far on the use of polyethylene glycol (PEG), with or without electrolytes, in the management of functional constipation and the treatment of fecal impaction. METHODOLOGY: Search on MEDLINE, EMBASE and Cochrane databases until May 2016 of all publications adjusted to the following terms: constipation AND/OR fecal impaction AND (PEG OR polyethylene glycol OR macrogol OR movicol OR idralax OR miralax OR transipeg OR forlax OR golytely OR isocolan OR mulytely) NOT colonoscopy...
November 22, 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27863592/nursing-interventions-in-stroke-care-delivery-an-evidence-based-clinical-review
#12
Dimitrios Theofanidis, Bernard Gibbon
INTRODUCTION: Generally, nursing interventions during the acute stages following a stroke aim at preventing secondary brain injury (intracranial hypertension), maintaining the airways (due to paralysis of the pharynx muscles), providing general body support (vital signs, fluid and electrolyte balance), and anticipating the occurrence of complications (atelectasis and pneumonia). AIM: This literature review is to prioritize nursing interventions for acute stroke and to update nursing roles and input considering recommended levels of evidence of care to date...
December 2016: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/27857513/difficulties-in-the-diagnosis-and-management-of-hyponatremia
#13
REVIEW
Mihaela Mocan, Lia Manuela Terheş, Sorin Nicu Blaga
Hyponatremia is the most common electrolyte imbalance encountered in clinical practice. Beside the difficulty of the etiological diagnosis, the general lack of awareness regarding the negative impact of hyponatremia on the quality of life and the lack of targeted treatments until recent years may be responsible for the poor management of the disorder. Therefore we consider of utmost importance to improve the knowledge regarding the diagnosis and management of hyponatremia, by underlining the difficulties of the etiological diagnosis and its management...
2016: Clujul Medical (1957)
https://www.readbyqxmd.com/read/27854090/effective-and-cheap-behavioral-modification-therapy-to-manage-complicated-polydipsia-and-seizures-in-a-chronic-mental-health-institute
#14
Yen-Wen Chen, Weilun Chung, Ching-Kuan Wu, Shih-Pin Hsu, Ping-Tao Tseng
PURPOSE: Polydipsia is one of the most serious and complicated problems causing morbidity and mortality in chronic mental health institutes. The pathophysiology of polydipsia in chronic schizophrenia remains unclear; as a result, no effective methods exist to deal with this serious problem. This report describes a patient with schizophrenia with polydipsia and seizures who benefitted from a behavioral modification program at a chronic mental health institute. CASE REPORT: A 56-year-old schizophrenic man did not have a history of physical illnesses or seizures and developed seizures following polydipsia...
June 15, 2016: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/27843077/renal-replacement-therapies-in-neonates-issues-and-ethics
#15
REVIEW
Lesley Rees
Chronic irreversible kidney disease requiring dialysis is rare in the neonate. Many such neonates are diagnosed following antenatal ultrasound with congenital abnormalities of the kidneys and urinary tract. There is an increased incidence of prematurity and infants that are small for gestational age. Given the natural improvement in renal function that occurs in the neonatal period, some with extremely poor renal function may, with careful management of fluid and electrolytes, be kept off dialysis until the creatinine reaches a nadir when a definitive plan can be made...
November 11, 2016: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27842634/a-review-of-the-peri-operative-management-of-paediatric-burns-identifying-adverse-events
#16
H Rode, C Brink, K Bester, M P Coleman, T Baisey, R Martinez
BACKGROUND: Burn injuries are common in poverty-stricken countries. The majority of patients with large and complex burns are referred to burn centres. Of the children who qualify for admission, according to burn admission criteria, about half require some kind of surgical procedure to obtain skin cover. These range from massive full-thickness fire burns to skin grafts for small, residual unhealed wounds. Burn anaesthetic procedures are of the most difficult to perform and are known for high complication rates...
November 2, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27834596/ventriculo-ureteral-shunt-insertion-using-percutaneous-nephrostomy-a-novel-minimally-invasive-option-in-a-patient-with-chronic-hydrocephalus-complicated-by-multiple-distal-ventriculoperitoneal-shunt-failures
#17
Ashok Pillai, Georgie Mathew, Sivasankaran Nachimuthu, Sanjeevan Vasudevan Kalavampara
The management of ventriculoperitoneal (VP) shunt failure is a common problem in neurosurgical practice. On occasion, extraperitoneal sites for CSF diversion are required when shunting to the peritoneal cavity has failed after multiple attempts. The authors report a novel minimally invasive procedure allowing cannulation of the ureter for the purpose of ventriculo-ureteral (VU) shunting. Sixteen years prior to presentation, this 46-year-old woman had contracted tuberculous meningitis and had chronic hydrocephalus, with multiple distal shunt failures in recent months...
November 11, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27833494/anesthetic-management-of-a-case-of-sanjad-sakati-syndrome
#18
A N Alshoaiby, M Rafiq, R Jan, M Shahbaz, A Faqeeh, M A Alsohaibani
Sanjad-Sakati syndrome is an autosomal recessive genetic disorder first described in Saudi Arabia. Anesthetic management of these patients is challenging due to airway difficulties, electrolyte imbalance, growth and mental retardation, and seizures. The anesthetic management of the syndrome is described in this case report.
October 2016: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/27826432/antidiabetic-effects-of-mangifera-indica-kernel-flour-supplemented-diet-in-streptozotocin-induced-type-2-diabetes-in-rats
#19
Emmanuel A Irondi, Ganiyu Oboh, Afolabi A Akindahunsi
Our previous report showed that Mangifera indica kernel flour (MIKF) is a rich source of pharmacologically important flavonoids and phenolic acids; and that its methanolic extract inhibits some key enzymes linked to the pathology and complications of type 2 diabetes (T2D) in vitro. Hence, this study evaluated the antidiabetic effects of 10% and 20% MIKF-supplemented diets in T2D in rats. T2D was induced in rats using a high-fat diet (HFD), low-dose streptozotocin (HFD/STZ) model, by feeding the rats with HFD for 2 weeks followed by single dose administration of STZ (40 mg/kg body weight, intraperitoneally)...
November 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27824535/update-on-the-management-of-intestinal-failure
#20
REVIEW
Shishira Bharadwaj, Parul Tandon, John M Rivas, Anne Furman, Lisa Moccia, Ashley Ratliff, Abdullah Shatnawei, Ezra Steiger, Donald F Kirby
Intestinal failure is a serious complication of conditions such as inflammatory bowel disease, mesenteric ischemia, and radiation enteritis--and of extensive bowel resection performed because of these diseases. Imbalances of fluids and electrolytes and poor nutritional status manifest as chronic diarrhea or increased ostomy output. Prompt referral to a center specializing in intestinal rehabilitation is key to achieving nutritional homeostasis and, in some cases, can help the patient return to oral food intake...
November 2016: Cleveland Clinic Journal of Medicine
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