keyword
MENU ▼
Read by QxMD icon Read
search

corneal confocal microscope

keyword
https://www.readbyqxmd.com/read/28912848/changes-in-the-anterior-cornea-during-the-early-stages-of-severe-myopia-prior-to-and-following-lasik-as-detected-by-confocal-microscopy
#1
Jinrong Zhao, Jinguo Yu, Liu Υang, Yang Liu, Shaozhen Zhao
The present study aimed to assess the microscopic changes of the epithelium and Bowman's layer under confocal microscopy during the early stages of severe myopia following laser in situ keratomileusis (LASIK). The study comprised 54 patients (54 eyes) with severe myopia and 65 patients (65 eyes) with low and moderate myopia, who underwent LASIK surgery at Tianjin Medical University Eye Hospital (Tianjin, China). In all patients, the epithelium, Bowman's layer and anterior stroma were examined prior to and 1, 7, 30, 90 and 180 days after the surgery, using in vivo confocal microscopy...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28894403/corneal-cell-morphology-in-keratoconus-a-confocal-microscopic-observation
#2
Somnath Ghosh, Haliza Abdul Mutalib, Sharanjeet Kaur, Rituparna Ghoshal, Shamala Retnasabapathy
PURPOSE: To evaluate corneal cell morphology in patients with keratoconus using an in vivo slit scanning confocal microscope. METHODS: A cross-sectional study was conducted to evaluate the corneal cell morphology of 47 keratoconus patients and 32 healthy eyes without any ocular disease. New keratoconus patients with different disease severities and without any other ocular co-morbidity were recruited from the ophthalmology department of a public hospital in Malaysia from June 2013 to May 2014...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28794613/association-of-fluorescein-anterior-corneal-mosaic-and-corneal-k-structures-by-in-vivo-laser-confocal-microscopy-in-patients-with-keratoconus
#3
Akira Kobayashi, Hideaki Yokogawa, Natsuko Mori, Toshinori Masaki, Kazuhisa Sugiyama
OBJECTIVE: To report the in vivo laser confocal microscopy findings of corneas with keratoconus, with special attention to abnormality of Bowman's layer and sub-Bowman's fibrous structures (Kobayashi-structures [K-structures]). METHODS: Sixteen keratoconic eyes in 8 consecutive patients with keratoconus (4 males, 4 females, mean age, 41.1 years) were included in this study. Slit-lamp biomicroscopic photos were taken with or without fluorescein staining. The existence of anterior corneal mosaic (ACM) after eyelid rubbing under fluorescein staining was documented...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28751986/evaluation-of-bleb-morphology-and-reduction-in-iop-and-glaucoma-medication-following-implantation-of-a-novel-gel-stent
#4
Antonio Maria Fea, Roberta Spinetta, Paola Maria Loredana Cannizzo, Giulia Consolandi, Carlo Lavia, Vittoria Aragno, Francesco Germinetti, Teresa Rolle
OBJECTIVE: To evaluate the efficacy and safety of the Xen Gel Stent and provide a macro- and microscopic analyses of bleb morphology. METHODS: A prospective 12-month study on patients with primary open-angle glaucoma. Patients underwent implantation of the XEN Gel Stent (Allergan INC, Dublin, Ireland) either alone or combined with a cataract surgery. Biomicroscopy, in vivo confocal microscopy (IVCM), and anterior segment-optical coherence tomography (AS-OCT) were used to assess bleb morphology...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28656670/the-corneal-nerve-density-in-the-sub-basal-plexus-decreases-with-increasing-myopia-a-pilot-study
#5
COMPARATIVE STUDY
Wendy W Harrison, Nicole M Putnam, Christine Shukis, Evelyn Nguyen, Kristen Reinard, Elizabeth Hundelt, Galina Vardanyan, Celine Gabai, Vladimir Yevseyenkov
PURPOSE: Myopia can cause many changes in the health of the eye. As it becomes more prevalent worldwide, more patients seek correction in the form of glasses, contact lenses and refractive surgery. In this study we explore the impact that high myopia has on central corneal nerve density by comparing sub basal nerve plexus density measured by confocal microscopy in a variety of refractive errors. METHODS: Seventy healthy adult subjects between the ages of 21-50 years participated in this study...
July 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28570722/use-of-corneal-confocal-microscopy-to-detect-corneal-nerve-loss-and-increased-dendritic-cells-in-patients-with-multiple-sclerosis
#6
Gulfidan Bitirgen, Zehra Akpinar, Rayaz A Malik, Ahmet Ozkagnici
Importance: Multiple sclerosis (MS) is characterized by demyelination, axonal degeneration, and inflammation. Corneal confocal microscopy has been used to identify axonal degeneration in several peripheral neuropathies. Objective: To assess corneal subbasal nerve plexus morphologic features, corneal dendritic cell (DC) density, and peripapillary retinal nerve fiber layer (RNFL) thickness in patients with MS. Design, Setting, and Participants: This single-center, cross-sectional comparative study was conducted at a tertiary referral university hospital between May 27, 2016, and January 30, 2017...
July 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28562149/in-vivo-laser-confocal-microscopy-using-the-hrt-rostock-cornea-module-diversity-and-diagnostic-implications-in-patients-with-uveitis
#7
Lyndell L Lim, Jing Xie, Chyn C Chua, Tiffany Wong, Lani T Hoang, Matthias D Becker, Eric B Suhler, James T Rosenbaum, Friederike Mackensen
PURPOSE: Keratic precipitates (KP) are a common feature of uveitis. We prospectively examined KP with the Heidelberg Retinal Tomograph II confocal laser scanning microscope and Rostock Corneal Module (HRT-RCM) to explore their diagnostic implications. METHODS: Prospective, observational, multicenter study. HRT-RCM images were classified by two masked observers. RESULTS: 120 scans on 120 eyes from 110 subjects were included. The majority (N = 93) had non-infectious uveitis...
May 31, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28426441/diagnosis-of-corneal-limbal-stem-cell-deficiency
#8
REVIEW
Kyeong Hwan Kim, Shahzad I Mian
PURPOSE OF REVIEW: A state of limbal stem cell deficiency (LSCD) can be secondary to a number of etiologies, resulting in either a reduction in the total number of limbal stem cells or an abnormality in stem cell function. Initially, the epithelium becomes irregular and hazy; however, this condition may progress to persistent corneal epithelial defects, stromal scarring, ulceration, and even perforation. Since LSCD secondary to a variety of etiologies may be reversible, and various factors are prognostic of disease progression, timely diagnosis is important...
July 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28378047/-confocal-microscope-examination-of-the-corneal-nerve-plexus-as-biomarker-for-systemic-diseases-view-from-the-corneal-nerve-plexus-on-diabetes-mellitus-disease
#9
S Baltrusch
It is estimated that approximately 50% of patients with diabetes mellitus suffer from polyneuropathy, which is frequently diagnosed too late. Consequently, the question arises whether imaging procedures of the eye, namely optical coherence tomography of the retina and confocal microscopy of the cornea are suitable for the diagnostics and follow-up control of neurodegenerative changes in patients with diabetes mellitus. De Clerck and co-workers could demonstrate this by a systematic review of studies. Of these studies 11 were further evaluated with respect to corneal confocal microscopy...
July 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28371196/cytoarchitecture-of-epithelial-inflammatory-infiltration-indicates-the-aetiology-of-infectious-keratitis
#10
Adrian Smedowski, Dorota Tarnawska, Michal Orski, Ewa Wroblewska-Czajka, Kai Kaarniranta, Pasquale Aragona, Edward Wylegala
PURPOSE: To analyse cytological features of corneal epithelium in infectious keratitis. METHODS: One hundred and eighteen patients (53 males and 65 females) diagnosed with acute stage of infectious keratitis (45 viral, 40 bacterial, 23 fungal, 10 Acanthamoeba keratitis) were included in study. We performed retrospective analysis of bright and blue-light slit-lamp photographs and in vivo corneal confocal microscopy scans of the corneal epithelium from five corneal regions (superior, inferior, temporal, nasal and central)...
April 3, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28346276/comparison-of-noncontact-specular-and-confocal-microscopy-for-evaluation-of-corneal-endothelium
#11
Jianyan Huang, Jyotsna Maram, Tudor C Tepelus, Srinivas R Sadda, Vikas Chopra, Olivia L Lee
PURPOSE: To compare endothelial cell analysis obtained by noncontact specular and confocal microscopy, using the Konan NSP-9900 and Nidek ConfoScan4 systems, respectively. METHODS: Three groups including 70 healthy eyes, 49 eyes with Fuchs endothelial corneal dystrophy (FECD), and 78 eyes with glaucoma were examined with both the Konan NSP-9900 specular microscope and the Nidek ConfocScan4 confocal microscope. Certified graders at the Doheny Image Reading Center compared corneal endothelial images from both instruments side by side to assess image quality...
March 24, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28316191/-in-vivo-confocal-microscopic-observation-of-corneal-changes-in-patients-with-chronic-stevens-johnson-syndrome-or-toxic-epidermal-necrolysis
#12
T T Gao, Y Li, J Liu, Q Long
Objective: To describe corneal alterations visible on in vivo confocal microscopy in patients with debilitating ocular sequelae caused by Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). Methods: Twenty-two eyes of 11 consecutive patients suffering from chronic SJS or TEN were studied using slit lamp and in vivo confocal microscopy in the Ophthalmology Outpatient Department of Peking Union Medical College Hospital from March 2014 to April 2015. Results: Dry eye with meibomian gland dysfunction (19 eyes of 10 patients, 86...
March 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28268563/automated-morphometric-description-of-human-corneal-endothelium-from-in-vivo-specular-and-confocal-microscopy
#13
F Scarpa, A Ruggeri
Corneal images acquired by in-vivo specular and confocal microscopy provide clinical information on the cornea endothelium health state. Indeed, the normal hexagonal shape of endothelial cells is usually affected by age and pathologies. At present, the analysis is based on manual or semi-automatic methods and the segmentation of a large number of endothelial cells is required for a meaningful estimation of the clinical parameters. We propose an automated method that detects the centers of endothelial cells by convolving the original image with customized two-dimensional kernels, derives a structure made by connected vertices from the recognized centers using the Euclidean distance, and fine-tunes the derived structure through a genetic algorithm, which combines information about the typical regularity of endothelial cells shape with the pixels intensity of the actual image...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28251081/effects-of-contact-lens-wearing-on-keratoconus-a-confocal-microscopy-observation
#14
Somnath Ghosh, Haliza A Mutalib, Sharanjeet-Kaur, Rituparna Ghoshal, Shamala Retnasabapathy
AIM: To evaluate the corneal cell morphology of new keratoconus patients wearing two different types of rigid gas-permeable (RGP) contact lenses for 1y. METHODS: Thirty nine eyes of 39 new keratoconus patients were selected and randomly fitted with two types of RGP contact lenses. Group 1 had 21 eyes with regular rigid gas-permeable (RRGP) contact lens and rest 18 eyes were in group 2 with specially designed rigid gas-permeable (SRGP) contact lens. Corneal cell morphology was evaluated using a slit scanning confocal microscope at no-lens wear and after 1y of contact lens wearing...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28226740/automated-morphometric-description-of-human-corneal-endothelium-from-in-vivo-specular-and-confocal-microscopy
#15
F Scarpa, A Ruggeri, F Scarpa, A Ruggeri, A Ruggeri, F Scarpa
Corneal images acquired by in-vivo specular and confocal microscopy provide clinical information on the cornea endothelium health state. Indeed, the normal hexagonal shape of endothelial cells is usually affected by age and pathologies. At present, the analysis is based on manual or semi-automatic methods and the segmentation of a large number of endothelial cells is required for a meaningful estimation of the clinical parameters. We propose an automated method that detects the centers of endothelial cells by convolving the original image with customized two-dimensional kernels, derives a structure made by connected vertices from the recognized centers using the Euclidean distance, and fine-tunes the derived structure through a genetic algorithm, which combines information about the typical regularity of endothelial cells shape with the pixels intensity of the actual image...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28130350/in-vivo-confocal-microscopic-characteristics-of-microsporidial-keratoconjunctivitis-in-immunocompetent-adults
#16
Chintan Malhotra, Arun Kumar Jain, Savleen Kaur, Deepika Dhingra, Varshitha Hemanth, Surya Prakash Sharma
BACKGROUND/AIMS: To describe in vivo confocal microscopy (IVCM) features of microsporidial keratoconjunctivitis in immunocompetent adult patients. METHODS: Patients suspected clinically to be suffering from microsporidial keratoconjunctivitis (ie, presence of unilateral follicular and/or papillary conjunctivitis in conjunction with multifocal, coarse corneal epitheliopathy) were subjected to IVCM with the Rostock Cornea Module of the Heidelberg Retinal Tomograph 3, and combined potassium hydroxide and calcofluor white (KOH+CFW) staining of the corneal scrapings, to detect the microsporidial spores...
September 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28127735/effects-of-panretinal-laser-photocoagulation-on-the-corneal-nerve-plexus-and-retinal-nerve-fiber-layer-in-retinal-vein-occlusion
#17
Gulfidan Bitirgen, Selman Belviranli, Rayaz A Malik, Hurkan Kerimoglu, Ahmet Ozkagnici
PURPOSE: To determine the effects of panretinal photocoagulation (PRP) on corneal sub-basal nerve plexus (SBNP) and peripapillary retinal nerve fiber layer (RNFL) thickness in patients with unilateral central retinal vein occlusion (CRVO) who had previously undergone PRP treatment. METHODS: Sixty-four eyes of 32 patients (19 male, 13 female) with unilateral ischemic type CRVO who had undergone PRP treatment at least 6 months previously were included in this cross-sectional study...
August 30, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27994400/in-vivo-confocal-microscopic-architecture-of-corneal-nerves-in-a-case-of-multiple-endocrine-neoplasia-type-2b
#18
Chintan Malhotra, Arun Kumar Jain, Bikram Thapa, Sabin Sahu
A detailed ocular examination and in vivo confocal microscopy (IVCM) using the Heidelberg retinal tomograph 3 with Rostock cornea module were performed in a patient with multiple endocrine neoplasia (MEN) 2b syndrome. Ocular findings included ptosis secondary to thickening of the lid margins, subconjunctival and perilimbal neuromas, and prominent corneal nerves extending up to the pupillary area. IVCM demonstrated structural alterations of both the main nerve trunks and the smaller branches. The main nerve trunks were grossly thickened while the smaller fibers were present in an intertwining manner in the anterior stroma...
October 2016: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/27941384/characterization-of-the-corneal-subbasal-nerve-plexus-in-limbal-stem-cell-deficiency
#19
COMPARATIVE STUDY
Pichaya Chuephanich, Chantaka Supiyaphun, Carolina Aravena, Tahir Kansu Bozkurt, Fei Yu, Sophie X Deng
PURPOSE: To quantify the changes in the subbasal nerve plexus in patients with limbal stem cell deficiency (LSCD) using in vivo laser scanning confocal microscopy. METHODS: In this retrospective cross-sectional comparative study, confocal images of 51 eyes of 37 patients with LSCD collected between 2010 and 2015 by the Heidelberg Retina Tomograph III Rostock Corneal Module Confocal Microscope were analyzed. Two independent observers evaluated the scans of the central cornea...
March 2017: Cornea
https://www.readbyqxmd.com/read/27898982/evaluation-of-corneal-cross-linking-for-treatment-of-fungal-keratitis-using-confocal-laser-scanning-microscopy-on-an-ex-vivo-human-corneal-model
#20
RANDOMIZED CONTROLLED TRIAL
Jawaher M Alshehri, David Caballero-Lima, M Chantal Hillarby, Susan G Shawcross, Arun Brahma, Fiona Carley, Nick D Read, Hema Radhakrishnan
Purpose: Some previous reports have established the use of photoactivated chromophore-induced corneal cross-linking (PACK-CXL) in treating fungal keratitis. The results of these case reports have often been conflicting. To systematically study the effect of PACK-CXL in the management of Fusarium keratitis, we have developed an ex vivo model of human corneal infection using eye-banked human corneas. Methods: Sixteen healthy ex vivo human corneas were divided into four study groups: (1) untreated control, (2) cross-linked, (3) infected with fungal spores, and (4) infected with fungal spores and then cross-linked...
November 1, 2016: Investigative Ophthalmology & Visual Science
keyword
keyword
120671
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"