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https://www.readbyqxmd.com/read/29458102/%C3%AE-irradiated-chitosan-based-injectable-hydrogels-for-controlled-release-of-drug-montelukast-sodium
#1
Sadaf Hafeez, Atif Islam, Nafisa Gull, Abbas Ali, Shahzad Maqsood Khan, Saba Zia, Kalsoom Anwar, Saba Urooge Khan, Tahir Jamil
Novel pH-sensitive γ-irradiated low molecular weight chitosan (CS) (pre-irradiated) and poly (vinyl alcohol) (PVA) blended injectable hydrogels, crosslinked with varying concentrations of glycerol, were fabricated for drug delivery application. The effect of low molecular weight irradiated CS on controlled drug release was evaluated to address the problem of higher viscosity and lower solubility of high molecular weight CS. The FTIR spectra of hydrogels depicted the presence of all the incorporated functional groups and the developed interactions (physical and chemical)...
February 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29453556/effects-of-increasing-dietary-protein-supplies-on-milk-yield-milk-composition-and-nitrogen-use-efficiency-in-lactating-buffalo
#2
Muhammad Naveed-Ul-Haque, Muhammad Uzair Akhtar, Rizwan Munnawar, Saba Anwar, Anjum Khalique, Murtaza Ali Tipu, Fayyaz Ahmad, Muhammad Qamer Shahid
Nitrogen efficiency of lactating buffalo can be increased by providing dietary crude protein (CP) precisely to the requirement. Twelve lactating Nili-Ravi buffaloes (6 primiparous and 6 multiparous) at 76 ± 37.5 days in milk (DIM) were used in this study. The treatments were diets providing three levels of CP (% DM basis): (1) low-protein = 11%; (2) medium-protein = 13.1%; (3) high-protein = 14.2% according to a 3 × 3 Latin square design. The period length of each treatment was 21 days and the total duration of experiment was 63 days...
February 16, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29452293/genetic-diversity-and-functional-analysis-of-oipa-gene-in-association-with-other-virulence-factors-among-helicobacter-pylori-isolates-from-iranian-patients-with-different-gastric-diseases
#3
Nastaran Farzi, Abbas Yadegar, Hamid Asadzadeh Aghdaei, Yoshio Yamaoka, Mohammad Reza Zali
Helicobacter pylori (H. pylori) is one of the most genetically diverse bacterial pathogens that persistently colonizes the human gastric epithelium. This remarkable genomic plasticity may act as a driving force for successful adaptation and persistence of the bacteria in the harsh gastric environment. Outer inflammatory protein A (OipA) encoded by oipA gene (HP0638/hopH) is a member of the outer membrane proteins (OMPs) of H. pylori involved in induction of IL-8 secretion and is associated with development of peptic ulcer and gastric cancer...
February 13, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29451839/correlates-of-postpartum-visits-among-medicaid-recipients-an-analysis-using-claims-data-from-a-managed-care-organization
#4
Saba W Masho, Susan Cha, Nicole Karjane, Elizabeth McGee, Rashel Charles, Linda Hines, Susan G Kornstein
BACKGROUND: The postpartum care visit (PPCV) plays an important role in ensuring the well-being of mother and infant. This study sought to assess correlates of PPCV attendance among women who are at high risk of nonattendance. MATERIALS AND METHODS: This study used deidentified medical claims data from Virginia Premier-a nonprofit Managed Care Organization that provides health insurance for Medicaid beneficiaries. The association between various correlates and PPCV attendance was examined using multiple logistic regression analyses...
February 16, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29448120/imaging-features-of-malignant-abdominal-neuroendocrine-tumors-with-rare-presentation
#5
Giuseppe Corrias, Serena Monti, Natally Horvat, Laura Tang, Olca Basturk, Luca Saba, Lorenzo Mannelli
BACKGROUND: Gastroenteropancreatic neuroendocrine tumors (NETs) are rare entities arising from neuroendocrine cells in the gastroenteric tract and pancreas. The purpose of this article is to present four cases of gastroenteropancreatic NETs that featured a challenging diagnosis. CASE PRESENTATION: We report a case series of four NETs, each with different features. All NETs were suspected based on clinical and biochemical data. The workup of the abnormalities was performed with CT, PET or MRI...
February 8, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29441700/knowledge-about-cervical-cancer-and-barriers-toward-cervical-cancer-screening-among-hiv-positive-women-attending-public-health-centers-in-addis-ababa-city-ethiopia
#6
Saba Shiferaw, Adamu Addissie, Muluken Gizaw, Selamawit Hirpa, Wondimu Ayele, Sefonias Getachewe, Eva J Kantelhardt, Mathewos Assefa, Ahmedin Jemal
Screening rate for cervical cancer among HIV-infected women and among women overall is low in Ethiopia despite the high burden of the disease and HIV infection, which increases cervical cancer risk. In this paper, we assessed knowledge about cervical cancer symptoms, prevention, early detection, and treatment and barriers to screening among HIV-positive women attending community health centers for HIV-infection management in Addis Ababa. A cross-sectional survey of 581 HIV-positive women aged 21-64 years old attending 14 randomly selected community health centers without cervical cancer screening service in Addis Ababa...
February 14, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29441413/distribution-and-health-risk-assessment-of-natural-fluoride-of-drinking-groundwater-resources-of-isfahan-iran-using-gis
#7
Saba Aghapour, Bijan Bina, Mohammad Javad Tarrahi, Fahimeh Amiri, Afshin Ebrahimi
Fluoride (F) contamination in groundwater can be problematic to human health. This study evaluated the concentration of fluoride in groundwater resources of Isfahan Province, the central plateau of Iran, and its related health issues to the inhabitant populations. For this purpose, 573 drinking groundwater samples were analyzed in 2016 by using the spectrophotometric method. Non-carcinogenic health risks due to F exposure through consumption of drinking water were assessed using the US EPA method. In addition, the associated zoning maps of the obtained results were presented using geographic information system (GIS)...
February 13, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29440293/a-correlative-analysis-of-pd-l1-pd-1-pd-l2-egfr-her2-and-her3-expression-in-oropharyngeal-squamous-cell-carcinoma
#8
Conor E Steuer, Christopher C Griffith, Sreenivas Nannapaneni, Mihir R Patel, Yuan Liu, Kelly R Magliocca, Mark W El-Deiry, Cynthia Cohen, Taofeek K Owonikoko, Dong M Shin, Zhuo Georgia Chen, Nabil F Saba
We explored potential associations of the PD-1/PD-L1/PD-L2 pathway with clinical characteristics, outcome, and expression of EGFR, HER2, HER3 in oropharyngeal squamous cell carcinoma (OPSCC) using an institutional database. Protein expression was assessed by immunohistochemistry on tissue microarray sections (EGFR, HER2, HER3) or whole tissue sections (PD-1/PD-L1/PD-L2). Expression of EGFR, HER2, HER3, PD-L1, and PD-L2 was quantified on tumor cells. Maximum density of PD-1 positive lymphocytes was measured on a scale of 0-4 within the tumor mass and peritumoral stroma...
February 13, 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29439079/primary-outcome-switching-among-drug-trials-with-and-without-principal-investigator-financial-ties-to-industry-a-cross-sectional-study
#9
Christopher W Jones, Benjamin S Misemer, Timothy F Platts-Mills, Rosa Ahn, Alexandra Woodbridge, Ann Abraham, Susan Saba, Deborah Korenstein, Erin Madden, Salomeh Keyhani
OBJECTIVES: To determine the relationship between manufacturer-related financial ties among investigators of published drug trials and rates of discrepant registered and published primary trial outcomes. DESIGN: Cross-sectional study. SETTING: Human subjects drug trials published in 'core clinical' MEDLINE journals in 2013. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary study endpoint was the presence of a prospectively registered, clearly defined primary outcome that matched the published primary outcome for each included trial...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438514/antiarrhythmic-drugs-clinical-use-and-clinical-decision-making-a-consensus-document-from-the-european-heart-rhythm-association-ehra-and-european-society-of-cardiology-esc-working-group-on-cardiovascular-pharmacology-endorsed-by-the-heart-rhythm-society-hrs
#10
Gheorghe-Andrei Dan, Antoni Martinez-Rubio, Stefan Agewall, Giuseppe Boriani, Martin Borggrefe, Fiorenzo Gaita, Isabelle van Gelder, Bulent Gorenek, Juan Carlos Kaski, Keld Kjeldsen, Gregory Y H Lip, Bela Merkely, Ken Okumura, Jonathan P Piccini, Tatjana Potpara, Birgitte Klindt Poulsen, Magdi Saba, Irina Savelieva, Juan L Tamargo, Christian Wolpert
No abstract text is available yet for this article.
February 9, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29433489/predictors-of-inappropriate-and-excessive-use-of-reliever-medications-in-asthma-a-16-year-population-based-study
#11
Hamid Tavakoli, J Mark FitzGerald, Larry D Lynd, Mohsen Sadatsafavi
BACKGROUND: Understanding factors associated with the inappropriate or excessive use of short-acting beta agonists (SABA) can help develop better policies. METHODS: We used British Columbian (BC)'s administrative health data (1997-2014) to create a retrospective cohort of asthma patients aged between 14 and 55 years. The primary and secondary outcomes were, respectively, inappropriate and excessive use of SABA based on a previously validated definition. Exposures were categorised into groups comprising socio-demographic variables, indicators of type and quality of asthma care, and burden of comorbid conditions...
February 12, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29433272/capturing-consumer-perception-of-vegetable-freshness-in-a-simulated-real-life-taste-situation
#12
Fiorella Sinesio, Anna Saba, Marina Peparaio, Eleonora Saggia Civitelli, Flavio Paoletti, Elisabetta Moneta
Consumer testing in re-created purchase or consumption contexts may produce results with a higher external validity than laboratory testing and be a valid alternative to consumer testing in real-life contexts. Hence, the present study evaluates the utility of a novel immersive approach in sensory consumer testing. An immersive multisensory room was designed to reproduce consumption conditions close to real life, with large wall screen projections, audio and olfactory stimuli and furniture consistent with the video scenario...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29429429/functional-determinants-of-dietary-intake-in-community-dwelling-older-adults-a-dedipac-determinants-of-diet-and-physical-activity-systematic-literature-review
#13
Eva Kiesswetter, Eleonora Poggiogalle, Siliva Migliaccio, Lorenzo Maria Donini, Claire Sulmont-Rossé, Catherine Feart, Aleksandra Suwalska, Katarzyna Wieczorowska-Tobis, Wiktor Pałys, Dorota Łojko, Anna Saba, Fiorella Sinesio, Angela Polito, Elisabetta Moneta, Donatella Ciarapica, Johannes Brug, Dorothee Volkert
OBJECTIVE: The identification of determinants of dietary intake is an important prerequisite for the development of interventions to improve diet. The present systematic literature review aimed to compile the current knowledge on individual functional determinants of dietary intake in community-dwelling older adults. DESIGN: A systematic search was performed in PubMed, Scopus, Web of Science and the Cochrane Library. Titles, abstracts and full texts were screened according to predefined inclusion and exclusion criteria...
February 12, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29429262/-evaluation-of-asthma-disease-perception-from-china-national-asthma-control-survey
#14
W Q Wang, J T Lin, X Zhou, C Z Wang, M Huang, S X Cai, P Chen, Q C Lin, J Y Zhou, Y H Gu, Y D Yuan, D J Sun, X H Yang, L Yang, J M Huo, Z C Chen, P Jiang, J Zhang, X W Ye, H G Liu, H P Tang, R Y Liu, C T Liu, W Zhang, C P Hu, Y Q Chen, X J Liu, L M Dai, W Zhou, Y J Huang, J Y Xu
Objective: In order to evaluate disease perception of asthma patients in urban China and provide evidence for further specific patient education. Methods: A multi-center, cross-sectional, questionnaire-based survey was carried out in 30 general hospitals dispersed in 30 provinces of mainland China (except for Tibet) during Oct 2015 to May 2016. Information of disease perception [Question 1: the disease nature of asthma; Question 2: medication choice of first-line in chronic asthma; Question 3: the occasion of using short-acting aerosols of receptor agonists; Question 4: perception of asthma treatment goal; Question 5: reason for not using peak flow meter (PFM)] were collected from asthma patients of outpatient department...
February 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29427298/meningitis-as-a-consequence-of-otitis-media-in-a-child-referred-from-the-newborn-hearing-screening-programme-a-missed-opportunity
#15
Lorenza Matarazzo, Silvia Nider, Saba Battelino, Enrico Muzzi, Eva Orzan, Alessandro Ventura, Egidio Barbi
No abstract text is available yet for this article.
February 10, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29419413/congenital-hypogonadotropic-hypogonadism-and-constitutional-delay-of-growth-and-puberty-have-distinct-genetic-architectures
#16
Daniele Cassatella, Sasha Howard, James Acierno, Cheng Xu, Georgios Papadakis, Federico A Santoni, Andrew A Dwyer, Sara Santini, Gerasimos Sykiotis, Caroline Chambion, Jenny Meylan, Laura Marino, Lucie Favre, Jiankang Li, Xuanzhu Liu, Jian-Guo Zhang, Pierre Bouloux, Christian De Geyter, Anne De Paepe, Waljit S Dhillo, Jean-Marc Ferrara, Michael Hauschild, Mariarosaria Lang-Muritano, Johannes Lemke, Christa E Flück, Attila Nemeth, Franziska Phan-Hug, Duarte Pignatelli, Vera Popovic, Sandra Pekic, Richard Quinton, Gabor Szinnai, Dagmar l'Allemand, Daniel Konrad, Saba Sharif, Özlem Turhan Iyidir, Brian J Stevenson, Huanming Yang, Leo Dunkel, Nelly Pitteloud
OBJECTIVE: Congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) represent rare and common forms of GnRH deficiency, respectively. Both CDGP and CHH present with delayed puberty, and the distinction between these two entities during early adolescence is challenging. More than 30 genes have been implicated with CHH, while the genetic basis of CDGP is poorly understood. DESIGN: We characterized and compared the genetic architectures of CHH and CDGP, to test the hypothesis of a shared genetic basis between these disorders...
February 1, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29417860/an-insight-into-frequency-and-predictors-leading-psychiatric-patients-to-visit-faith-healers-a-hospital-based-cross-sectional-survey-karachi-pakistan
#17
Aneeta Khoso, Rafiq Ahmed Soomro, Ayesha Muquim Quraishy, Hammad Ali Khan, Saba Ismail, Mehrunnisa Nazaz, Sana Younus, Saima Zainab
BACKGROUND: Psychiatric illnesses have recently escalated in numbers, with patients resorting to various forms of healthcare providers, including faith healers. This delays early psychiatric treatment, resulting in further mental health deterioration of the patient. Various factors impact the mode of treatment preferred by psychiatric patients. AIMS: To determine the frequency of psychiatric patients visiting faith healers, presenting at the outpatient department of Liaquat National Hospital, Karachi, Pakistan, and to explore the predictors that direct them toward visiting faith healers...
February 1, 2018: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/29417482/fullerene-c60-for-enhancing-phytoremediation-of-urea-plant-wastewater-by-timber-plants
#18
Sara Yavari, Amirhossein Malakahmad, Nasiman B Sapari, Saba Yavari
Phytoremediation has been applied as a promising and cost-effective technique for removing nutrient pollutants from wastewater. In this study, the effect of fullerene C60 was assessed on enhancing the phytoremediation efficiency of teak plants over a period of 1 month. Teak plants were supplied with fullerene C60 (0, 25, or 50 mg L-1) and fed daily with two types of urea plant wastewater (with and without adding optimum ratio of phosphorus and potassium). The required volume of wastewater by the teak plants, nitrogen removal percentage, plant growth parameters (plant height, number of leaves, leaf surface area, and dry biomass), and nutrient content was recorded throughout the study...
February 7, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29417455/a-review-of-photodynamic-therapy-for-neoplasms-of-the-head-and-neck
#19
REVIEW
Francisco J Civantos, Barış Karakullukcu, Merrill Biel, Carl E Silver, Alessandra Rinaldo, Nabil F Saba, Robert P Takes, Vincent Vander Poorten, Alfio Ferlito
Photodynamic therapy (PDT) involves the use of a phototoxic drug which is activated by low powered laser light to destroy neoplastic cells. Multiple photosensitizers have been studied and tumors have been treated in a variety of head and neck sites over the last 30 years. PDT can effectively treat head and neck tumors, particularly those of the superficial spreading type, and the classic application of this technology has been in the patient with a wide field of dysplastic change and superficial carcinomatosis...
February 7, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29415075/the-other-campylobacters-not-innocent-bystanders-in-endemic-diarrhea-and-dysentery-in-children-in-low-income-settings
#20
Ruthly François, Pablo Peñataro Yori, Saba Rouhani, Mery Siguas Salas, Maribel Paredes Olortegui, Dixner Rengifo Trigoso, Nora Pisanic, Rosa Burga, Rina Meza, Graciela Meza Sanchez, Michael J Gregory, Eric R Houpt, James A Platts-Mills, Margaret N Kosek
BACKGROUND: Campylobacter is one of the main causes of gastroenteritis worldwide. Most of the current knowledge about the epidemiology of this food-borne infection concerns two species, C. coli and C. jejuni. Recent studies conducted in developing countries and using novel diagnostic techniques have generated evidence of the increasing burden and importance of other Campylobacter species, i.e. non-C. coli/jejuni. We performed a nested case-control study to compare the prevalence of C...
February 7, 2018: PLoS Neglected Tropical Diseases
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