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https://www.readbyqxmd.com/read/28314144/hydrophobicity-and-polymer-compatibility-of-poss-modified-wyoming-na-montmorillonite-for-developing-polymer-clay-nanocomposites
#1
Rustam Hojiyev, Yusuf Ulcay, Mirabbos Hojamberdiev, Mehmet S Çelik, William M Carty
The aim of the present work was to investigate the hydrophobicity and polymer compatibility of aminopropylisooctyl polyhedral oligomeric silsequioxane (POSS) - modified Na-montmorillonite (Na-MMT) towards developing polymer-clay nanocomposites. The effect of different concentrations of POSS on properties of Na-MMT was studied. The intercalation ability of the POSS molecules into the Na-MMT interlayer was analyzed by X-ray diffraction. It was found that the d001 value was increased with increasing the POSS concentration, indicating the successful intercalation of the POSS molecules into the Na-MMT interlayer...
March 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28298421/mimicry-of-an-hiv-broadly-neutralizing-antibody-epitope-with-a-synthetic-glycopeptide
#2
S Munir Alam, Baptiste Aussedat, Yusuf Vohra, R Ryan Meyerhoff, Evan M Cale, William E Walkowicz, Nathan A Radakovich, Kara Anasti, Lawrence Armand, Robert Parks, Laura Sutherland, Richard Scearce, M Gordon Joyce, Marie Pancera, Aliaksandr Druz, Ivelin S Georgiev, Tarra Von Holle, Amanda Eaton, Christopher Fox, Steven G Reed, Mark Louder, Robert T Bailer, Lynn Morris, Salim S Abdool-Karim, Myron Cohen, Hua-Xin Liao, David C Montefiori, Peter K Park, Alberto Fernández-Tejada, Kevin Wiehe, Sampa Santra, Thomas B Kepler, Kevin O Saunders, Joseph Sodroski, Peter D Kwong, John R Mascola, Mattia Bonsignori, M Anthony Moody, Samuel Danishefsky, Barton F Haynes
A goal for an HIV-1 vaccine is to overcome virus variability by inducing broadly neutralizing antibodies (bnAbs). One key target of bnAbs is the glycan-polypeptide at the base of the envelope (Env) third variable loop (V3). We have designed and synthesized a homogeneous minimal immunogen with high-mannose glycans reflective of a native Env V3-glycan bnAb epitope (Man9-V3). V3-glycan bnAbs bound to Man9-V3 glycopeptide and native-like gp140 trimers with similar affinities. Fluorophore-labeled Man9-V3 glycopeptides bound to bnAb memory B cells and were able to be used to isolate a V3-glycan bnAb from an HIV-1-infected individual...
March 15, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28297422/a-methodology-for-on-board-cbct-imaging-dose-using-optically-stimulated-luminescence-detectors
#3
Noor Mail, Muhammad Yusuf, Nazeeh Alothmany, A Abdulrahman Kinsara, Fahad Abdulkhaliq, Suliman M Ghamdi, Abdelhamid Saoudi
Cone-beam computed tomography CBCT systems are used in radiation therapy for patient alignment and positioning. The CBCT imaging procedure for patient setup adds substantial radiation dose to patient's normal tissue. This study presents a complete procedure for the CBCT dosimetry using the InLight optically-stimulated-luminescence (OSL) nanoDots. We report five dose parameters: the mean slice dose (DMSD); the cone beam dose index (CBDIW); the mean volume dose (DMVD); point-dose profile, D(FOV); and the off-field Dose...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28282061/hydroxychloroquine-retinopathy
#4
REVIEW
I H Yusuf, S Sharma, R Luqmani, S M Downes
Hydroxychloroquine (HCQ; Plaquenil) is used increasingly in the management of a variety of autoimmune disorders, with well established roles in dermatology and rheumatology and emerging roles in oncology. Hydroxychloroquine has demonstrated a survival benefit in patients with systemic lupus erythematosus; some clinicians advocate its use in all such patients. However, Hydroxychloroquine and chloroquine (CQ) have been associated with irreversible visual loss due to retinal toxicity. Hydroxychloroquine retinal toxicity is far more common than previously considered; an overall prevalence of 7...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28274899/acoustic-analysis-of-used-tuning-forks
#5
Mustafa Yüksel, Yusuf Kemal Kemaloğlu
OBJECTIVE: In this study, we evaluated used aluminum tuning forks (TFs) for fundamental frequencies (FF), overtones, and decay times. MATERIALS AND METHODS: In total, 15 used (1 C1, 11 C2, and 3 C3) and 1 unused (C2) TFs were tuned, and the recorded sound data were analyzed using the Praat sound analysis program. RESULTS: It was found that FFs of the recorded sounds produced by the used C2-TFs presented a high variability from 0.19% to 74...
March 9, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28269031/towards-development-of-a-mobile-rf-doppler-sensor-for-continuous-heart-rate-variability-and-blood-pressure-monitoring
#6
Insoo Kim, Yusuf A Bhagat
The standard in noninvasive blood pressure (BP) measurement is an inflatable cuff device based on the oscillometric method, which poses several practical challenges for continuous BP monitoring. Here, we present a novel ultra-wide band RF Doppler radar sensor for next-generation mobile interface for the purpose of characterizing fluid flow speeds, and for ultimately measuring cuffless blood flow in the human wrist. The system takes advantage of the 7.1~10.5 GHz ultra-wide band signals which can reduce transceiver complexity and power consumption overhead...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28249163/vaccine-elicitation-of-high-mannose-dependent-neutralizing-antibodies-against-the-v3-glycan-broadly-neutralizing-epitope-in-nonhuman-primates
#7
Kevin O Saunders, Nathan I Nicely, Kevin Wiehe, Mattia Bonsignori, R Ryan Meyerhoff, Robert Parks, William E Walkowicz, Baptiste Aussedat, Nelson R Wu, Fangping Cai, Yusuf Vohra, Peter K Park, Amanda Eaton, Eden P Go, Laura L Sutherland, Richard M Scearce, Dan H Barouch, Ruijun Zhang, Tarra Von Holle, R Glenn Overman, Kara Anasti, Rogier W Sanders, M Anthony Moody, Thomas B Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L Letvin, Gary J Nabel, David C Montefiori, Georgia D Tomaras, Hua-Xin Liao, S Munir Alam, Samuel J Danishefsky, Barton F Haynes
Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine whether immunization could induce antibodies to the V3-glycan bnAb binding site, we repetitively immunized macaques over a 4-year period with an Env expressing V3-high mannose glycans. Env immunizations elicited plasma antibodies that neutralized HIV-1 expressing only high-mannose glycans-a characteristic shared by early bnAb B cell lineage members...
February 28, 2017: Cell Reports
https://www.readbyqxmd.com/read/28239450/erratum-to-scaling-up-strategies-of-the-chronic-respiratory-disease-programme-of-the-european-innovation-partnership-on-active-and-healthy-ageing-action-plan-b3-area-5
#8
J Bousquet, J Farrell, G Crooks, P Hellings, E H Bel, M Bewick, N H Chavannes, J Correia de Sousa, A A Cruz, T Haahtela, G Joos, N Khaltaev, J Malva, A Muraro, M Nogues, S Palkonen, S Pedersen, C Robalo-Cordeiro, B Samolinski, T Strandberg, A Valiulis, A Yorgancioglu, T Zuberbier, A Bedbrook, W Aberer, M Adachi, A Agusti, C A Akdis, M Akdis, J Ankri, A Alonso, I Annesi-Maesano, I J Ansotegui, J M Anto, S Arnavielhe, H Arshad, C Bai, I Baiardini, C Bachert, A K Baigenzhin, C Barbara, E D Bateman, B Beghé, A Ben Kheder, K S Bennoor, M Benson, K C Bergmann, T Bieber, C Bindslev-Jensen, L Bjermer, H Blain, F Blasi, A L Boner, M Bonini, S Bonini, S Bosnic-Anticevitch, L P Boulet, R Bourret, P J Bousquet, F Braido, A H Briggs, C E Brightling, J Brozek, R Buhl, P G Burney, A Bush, F Caballero-Fonseca, D Caimmi, M A Calderon, P M Calverley, P A M Camargos, G W Canonica, T Camuzat, K H Carlsen, W Carr, A Carriazo, T Casale, A M Cepeda Sarabia, L Chatzi, Y Z Chen, R Chiron, E Chkhartishvili, A G Chuchalin, K F Chung, G Ciprandi, I Cirule, L Cox, D J Costa, A Custovic, R Dahl, S E Dahlen, U Darsow, G De Carlo, F De Blay, T Dedeu, D Deleanu, E De Manuel Keenoy, P Demoly, J A Denburg, P Devillier, A Didier, A T Dinh-Xuan, R Djukanovic, D Dokic, H Douagui, G Dray, R Dubakiene, S R Durham, M S Dykewicz, Y El-Gamal, R Emuzyte, L M Fabbri, M Fletcher, A Fiocchi, A Fink Wagner, J Fonseca, W J Fokkens, F Forastiere, P Frith, M Gaga, A Gamkrelidze, J Garces, J Garcia-Aymerich, B Gemicioğlu, J E Gereda, S González Diaz, M Gotua, I Grisle, L Grouse, Z Gutter, M A Guzmán, L G Heaney, B Hellquist-Dahl, D Henderson, A Hendry, J Heinrich, D Heve, F Horak, J O' B Hourihane, P Howarth, M Humbert, M E Hyland, M Illario, J C Ivancevich, J R Jardim, E J Jares, C Jeandel, C Jenkins, S L Johnston, O Jonquet, K Julge, K S Jung, J Just, I Kaidashev, M R Khaitov, O Kalayci, A F Kalyoncu, T Keil, P K Keith, L Klimek, B Koffi N'Goran, V Kolek, G H Koppelman, M L Kowalski, I Kull, P Kuna, V Kvedariene, B Lambrecht, S Lau, D Larenas-Linnemann, D Laune, L T T Le, P Lieberman, B Lipworth, J Li, K Lodrup Carlsen, R Louis, W MacNee, Y Magard, A Magnan, B Mahboub, A Mair, I Majer, M J Makela, P Manning, S Mara, G D Marshall, M R Masjedi, P Matignon, M Maurer, S Mavale-Manuel, E Melén, E Melo-Gomes, E O Meltzer, A Menzies-Gow, H Merk, J P Michel, N Miculinic, F Mihaltan, B Milenkovic, G M Y Mohammad, M Molimard, I Momas, A Montilla-Santana, M Morais-Almeida, M Morgan, R Mösges, J Mullol, S Nafti, L Namazova-Baranova, R Naclerio, A Neou, H Neffen, K Nekam, B Niggemann, G Ninot, T D Nyembue, R E O'Hehir, K Ohta, Y Okamoto, K Okubo, S Ouedraogo, P Paggiaro, I Pali-Schöll, P Panzner, N Papadopoulos, A Papi, H S Park, G Passalacqua, I Pavord, R Pawankar, R Pengelly, O Pfaar, R Picard, B Pigearias, I Pin, D Plavec, D Poethig, W Pohl, T A Popov, F Portejoie, P Potter, D Postma, D Price, K F Rabe, F Raciborski, F Radier Pontal, S Repka-Ramirez, S Reitamo, S Rennard, F Rodenas, J Roberts, J Roca, L Rodriguez Mañas, C Rolland, M Roman Rodriguez, A Romano, J Rosado-Pinto, N Rosario, L Rosenwasser, M Rottem, D Ryan, M Sanchez-Borges, G K Scadding, H J Schunemann, E Serrano, P Schmid-Grendelmeier, H Schulz, A Sheikh, M Shields, N Siafakas, Y Sibille, T Similowski, F E R Simons, J C Sisul, I Skrindo, H A Smit, D Solé, T Sooronbaev, O Spranger, R Stelmach, P J Sterk, J Sunyer, C Thijs, T To, A Todo-Bom, M Triggiani, R Valenta, A L Valero, E Valia, E Valovirta, E Van Ganse, M van Hage, O Vandenplas, T Vasankari, B Vellas, J Vestbo, G Vezzani, P Vichyanond, G Viegi, C Vogelmeier, T Vontetsianos, M Wagenmann, B Wallaert, S Walker, D Y Wang, U Wahn, M Wickman, D M Williams, S Williams, J Wright, B P Yawn, P K Yiallouros, O M Yusuf, A Zaidi, H J Zar, M E Zernotti, L Zhang, N Zhong, M Zidarn, J Mercier
[This corrects the article DOI: 10.1186/s13601-016-0116-9.].
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28230540/revealing-magnetic-ordering-and-spin-phonon-coupling-in-y1-xtbxmno3-0-1-%C3%AF-x-%C3%AF-0-3-compounds
#9
Keka R Chakraborty, Barnita Paul, Rakesh Shukla, Psr Krishna, Amit Kumar, Mayuresh Mukadam, Balaji Mandal, Anushree Roy, Avesh Tyagi, S Yusuf
The structural and magnetic properties of the Y1-xTbxMnO3(0.1x0.3)compoundswere investigated.Neutron diffraction patterns for all three samples,recorded at room temperature (RT),were fitted to the nuclear structure confirming the paramagnetic nature of the compounds. At 2.8 K,for the x = 0.1 sample magnetic moments of the Tb3+ionic as well as Mn3+ionic were ordered.At 5 K for the x = 0.2 sample only the Mn3+ionic magnetic moments were ordered. Therewere six sites for Mn atoms. Three on the z = 0 plane and three on the z = 0...
February 23, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28229559/size-dependent-consequences-of-exogenous-cortisol-manipulation-on-overwinter-survival-and-condition-of-largemouth-bass
#10
Jonathan D Midwood, Kathryn S Peiman, Aja E W Burt, Mohammed Yusuf Sarker, Michael A Nannini, David H Wahl, Steven J Cooke
Little is known about the size-dependent consequences of stressors on wild animals, which is particularly relevant during winter where size-specific trends in survival are common. Here, exogenous cortisol manipulation was used to investigate the effect of a physiological challenge on overwinter mortality and spring condition of largemouth bass (Micropterus salmoides) across a range of body sizes. Fish were wild-caught in the fall, assigned into either control or cortisol manipulated treatments, and held in replicated experimental ponds...
February 23, 2017: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/28227244/towards-development-of-a-mobile-rf-doppler-sensor-for-continuous-heart-rate-variability-and-blood-pressure-monitoring
#11
Insoo Kim, Yusuf A Bhagat, Insoo Kim, Yusuf A Bhagat, Insoo Kim, Yusuf A Bhagat
The standard in noninvasive blood pressure (BP) measurement is an inflatable cuff device based on the oscillometric method, which poses several practical challenges for continuous BP monitoring. Here, we present a novel ultra-wide band RF Doppler radar sensor for next-generation mobile interface for the purpose of characterizing fluid flow speeds, and for ultimately measuring cuffless blood flow in the human wrist. The system takes advantage of the 7.1~10.5 GHz ultra-wide band signals which can reduce transceiver complexity and power consumption overhead...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224268/serum-serotonin-leptin-and-adiponectin-changes-in-women-with-postpartum-depression-controlled-study
#12
Gazi Yildiz, Mehmet Baki Senturk, Pinar Yildiz, Yusuf Cakmak, Mehmet Sukru Budak, Erbil Cakar
PURPOSE: Postpartum depression (PPD) affects nearly 10% of mothers after delivery and has many serious results. Although many factors associated with PPD, the etiology, and pathophysiology of PPD are not known completely. The relationship between serum serotonin concentration and depression is well known, but there are no enough data regarding the serum change of leptin and adiponectin. The aims of this study are to research the level of serum serotonin, leptin,s and adiponectin concentrations in women with PPD...
February 21, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28220309/transseptal-suturing-technique-in-septoplasty-impact-on-bacteremia-and-nosocomial-colonization
#13
Onur Ismi, Cengiz Ozcan, Yusuf Vayısoğlu, Candan Öztürk, Sebahat Aslan Tek, Kemal Görür
Although effects of Merocel(®) nasal packs and silicone splints on nasal flora alterations and bacteremia formation after septoplasty were assessed before, the effect of transseptal suturing technique has not been studied yet. The objective of this study is to compare nasal flora alterations and bacteremia occurrence rates between Merocel packs, silicone splints, and transseptal suturing technique in septoplasty. Ninety patients were divided into three groups randomly: Merocel packing (Group M), silicone splint (Group S), and transseptal suturing without packing (Group T)...
February 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28190527/assessing-quality-of-life-in-diabetes-ii-deconstructing-measures-into-a-simple-framework
#14
REVIEW
Tricia S Tang, Fardowsa L A Yusuf, William H Polonsky, Lawrence Fisher
A growing number of instruments measuring diabetes-specific health-related quality of life (HRQOL) have been identified in previous systematic reviews, the most recent being published in 2008. The purpose of this paper is report on an updated systematic review of diabetes-specific HRQOL measures highlighting the time period 2006-2016; to deconstruct existing diabetes-specific HRQOL measures into a simple framework for evaluating the goodness-of-fit between specific research needs and instrument characteristics; and to present core characteristics of measures not yet reported in other reviews to further facilitate scale selection...
October 26, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28186509/hydroxychloroquine-retinopathy-an-emerging-problem
#15
M Latasiewicz, H Gourier, I H Yusuf, R Luqmani, S M Sharma, S M Downes
PurposeThe aim of this case series is to raise awareness of the emerging issue of serious retinal damage caused by the prolonged use of hydroxychloroquine (HCQ) and the importance of adequate and appropriate monitoring of visual function during treatment.Patient and methodsThis is a small retrospective case series of 3 patients on long-term HCQ who developed serious symptomatic retinal toxicity confirmed on imaging and functional testing.ResultsAll 3 patients were treated with HCQ for over 15 years; two for rheumatoid arthritis (RA), and the third for systemic lupus erythematosus (SLE)...
February 10, 2017: Eye
https://www.readbyqxmd.com/read/28183036/which-one-is-more-effective-for-analgesia-in-infratentorial-craniotomy-the-scalp-block-or-local-anesthetic-infiltration
#16
RANDOMIZED CONTROLLED TRIAL
Eren Fatma Akcil, Ozlem Korkmaz Dilmen, Hayriye Vehid, Lutfiye Serap Ibısoglu, Yusuf Tunali
OBJECTIVES: The most painful stages of craniotomy are the placement of the pin head holder and the skin incision. The primary aim of the present study is to compare the effects of the scalp block and the local anesthetic infiltration with bupivacaine 0.5% on the hemodynamic response during the pin head holder application and the skin incision in infratentorial craniotomies. The secondary aims are the effects on pain scores and morphine consumption during the postoperative 24h. METHODS: This prospective, randomized and placebo controlled study included forty seven patients (ASA I, II and III)...
March 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28174104/new-1-4-dihydro-1-8-naphthyridine-derivatives-as-dna-gyrase-inhibitors
#17
Hülya Karaca Gençer, Serkan Levent, Ulviye Acar Çevik, Yusuf Özkay, Sinem Ilgın
Owing to the growing need for novel antibacterial agents, we synthesized a novel series of fluoroquinolones including 7-substituted-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid derivatives, which were tested against clinically relevant Gram positive and Gram negative bacteria. Chemical structures of the synthesized compounds were identified using spectroscopic methods. In vitro antimicrobial effects of the compounds were determined via microdilution assay. Microbiological examination revealed that compounds 13 and 14 possess a good antibacterial profile...
January 26, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28116279/bilateral-femoral-fracture-in-a-newborn-with-myelomeningocele-at-cesarean-section-a-case-report
#18
Yusuf Erdem, Serkan Akpancar, M Hanifi Gemci
INTRODUCTION: Femur fractures as a result of birth trauma can still occur during the C/S, in spite of recent developments of surgical and anesthetic techniques. In this study, we aimed to present a rare case of a newborn with myelomeningocele who delivered by cesarean section due to breech presentation and sustained bilateral fracture of femoral shaft. CASE PRESENTATION: A 2690 g female newborn with myelomeningocele sustained bilateral femoral shaft fractures during cesarean section...
July 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28107922/-rough-guide-evanescent-wave-optrode-for-colorimetric-metalloporphyrine-sensors
#19
Abraham Kirwa Tuwei, Nicholas H Williams, Mohammad Yusuf Mulla, Corrado Di Natale, Roberto Paolesse, Martin Grell
When films of zinc 5-(4-carboxyphenyl),10,15,20-triphenyl porphyrin (ZnTPP) are exposed to waterborne amine in pH- neutral or alkaline media, both Q- band and Soret band respond with a change of absorbance due to the donation of amine 'lone pair' electrons to the metalloprophyrin π orbital. However, this is difficult to reveal with a conventional spectrometer even under high amine concentration. We therefore introduce optical fibres coated with ZnTPP into a bespoke 'light balance' evanescent wave absorbance meter [doi:10...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28104186/effects-of-bidi-smoking-on-all-cause-mortality-and-cardiorespiratory-outcomes-in-men-from-south-asia-an-observational-community-based-substudy-of-the-prospective-urban-rural-epidemiology-study-pure
#20
MyLinh Duong, Sumathy Rangarajan, Xiaohe Zhang, Kieran Killian, Prem Mony, Sumathi Swaminathan, Ankalmadagu Venkatsubbareddy Bharathi, Sanjeev Nair, Krishnapillai Vijayakumar, Indu Mohan, Rajeev Gupta, Deepa Mohan, Shanthi Rani, Viswanathan Mohan, Romaina Iqbal, Khawar Kazmi, Omar Rahman, Rita Yusuf, Lakshmi Venkata Maha Pinnaka, Rajesh Kumar, Paul O'Byrne, Salim Yusuf
BACKGROUND: Bidis are minimally regulated, inexpensive, hand-rolled tobacco products smoked in south Asia. We examined the effects of bidi smoking on baseline respiratory impairment, and prospectively collected data for all-cause mortality and cardiorespiratory events in men from this region. METHODS: This substudy of the international, community-based Prospective Urban Rural Epidemiology (PURE) study was done in seven centres in India, Pakistan, and Bangladesh...
February 2017: Lancet Global Health
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