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https://www.readbyqxmd.com/read/28544784/presynaptic-congenital-myasthenic-syndrome-with-a-homozygous-sequence-variant-in-lama5-combines-myopia-facial-tics-and-failure-of-neuromuscular-transmission
#1
Ricardo A Maselli, Juan Arredondo, Jessica Vázquez, Jessica X Chong, Michael J Bamshad, Deborah A Nickerson, Marian Lara, Fiona Ng, Victoria L Lo, Peter Pytel, Craig M McDonald
Defects in genes encoding the isoforms of the laminin alpha subunit have been linked to various phenotypic manifestations, including brain malformations, muscular dystrophy, ocular defects, cardiomyopathy, and skin abnormalities. We report here a severe defect of neuromuscular transmission in a consanguineous patient with a homozygous variant in the laminin alpha-5 subunit gene (LAMA5). The variant c.8046C>T (p.Arg2659Trp) is rare and has a predicted deleterious effect. The affected individual, who also carries a rare homozygous sequence variant in LAMA1, had muscle weakness, myopia, and facial tics...
May 25, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28533015/in%C3%A2-vitro-comparison-of-the-load-bearing-capacity-of-ceramic-and-metal-ceramic-resin-bonded-fixed-dental-prostheses-in-the-posterior-region
#2
Wolfgang Bömicke, Moritz Waldecker, Johannes Krisam, Peter Rammelsberg, Stefan Rues
STATEMENT OF PROBLEM: The clinical use of ceramic resin-bonded fixed dental prostheses (RBFDPs) in the posterior region is desirable for esthetic and biological reasons but has been associated with many technical problems, including fractures or chipping of the veneer. Although these problems may be overcome by using monolithic zirconia, information is lacking about the load-bearing capacity of resin-bonded monolithic zirconia restorations for replacing a molar. PURPOSE: The purpose of this in vitro study was to compare the load-bearing capacity (Fu), the load at initial damage (F1d), and the failure pattern of posterior RBFDPs fabricated from monolithic zirconia (MZr), veneered zirconia (VZr), and veneered cobalt-chromium (VCo)...
May 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28528931/evaluation-of-alternative-monomers-to-hema-for-dental-applications
#3
Sven Tauscher, Jörg Angermann, Yohann Catel, Norbert Moszner
OBJECTIVE: The objective of this work is to find potential alternative monomers to 2-hydroxyethyl methacrylate (HEMA) for dental materials (self-etch adhesives and luting composites). METHODS: Monomers 1-9 were tested as potential HEMA substitutes. Methacrylates 4, 5 and 6 and (N-methyl)acrylamides 7-9 were synthesized and characterized by (1)H NMR spectroscopy. The reactivity of each monomer was studied using photo-DSC. Mixtures of monomers 1-9 with the urethane dimethacrylate UDMA (1/1: wt/wt) were formulated and cured...
May 18, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28527812/adhesive-interfacial-characteristics-and-the-related-bonding-performance-of-four-self-etching-adhesives-with-different-functional-monomers-applied-to-dentin
#4
Ruirui Wang, Yilin Shi, Tingting Li, Yueping Pan, Yu Cui, Wenwei Xia
OBJECTIVES: To examine the interfacial chemical and morphological characteristics of four self-etching adhesives bonded to dentin with different functional monomers. Further, to evaluate the effects of this interaction between functional monomers and dentin on short-term in vitro bonding performance of the four adhesives. METHODS: Clearfil SE Bond (CSE) and Scotchbond Universal (SU) containing 10-methacryloxydecyl dihydrogen phosphate (10-MDP), Optibond XTR (OX) containing glycero-phosphate dimethacrylate (GPDM), and Adper Easy One (AEO) containing 6-methacryloyloxyhexyl dihydrogen phosphate (6-MHP) were applied to the dentin surface according to the instructions supplied with each...
May 17, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28527695/cytoprotection-proliferation-and-epidermal-differentiation-of-adipose-tissue-derived-stem-cells-on-emu-oil-based-electrospun-nanofibrous-mat
#5
Younes Pilehvar-Soltanahmadi, Mohammad Nouri, Mikaël M Martino, Amir Fattahi, Effat Alizadeh, Masoud Darabi, Mohammad Rahmati-Yamchi, Nosratollah Zarghami
Electrospun nanofibrous scaffolds containing natural substances with wound healing properties such as Emu oil (EO) may have a great potential for increasing the efficiency of stem cell-based skin bioengineering. For this purpose, EO blended PCL/PEG electrospun nanofibrous mats were successfully fabricated and characterized using FE-SEM, FTIR and Universal Testing Machine. The efficiency of the scaffolds in supporting the adherence, cytoprotection, proliferation and differentiation of adipose tissue-derived stem cells (ADSCs) to keratinocyte was evaluated...
May 17, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28521113/real-time-imaging-of-gap-progress-during-and-after-composite-polymerization
#6
J Hayashi, Y Shimada, J Tagami, Y Sumi, A Sadr
The aims of this study were to observe the behavior of composite and formation of gaps during and immediately after light polymerization using swept source optical coherence tomography (OCT) and to compare the interfacial integrity of adhesives in cavities through 3-dimensional (3D) image analysis. Forty tapered cylindrical cavities (4-mm diameter, 2-mm depth) were prepared in bovine incisors and restored using Bond Force (BF), Scotchbond Universal Adhesive (SBU), OptiBond XTR (XTR), or Clearfil SE Bond 2 (SE2), followed by Estelite Flow Quick flowable composite...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28512485/effect-of-blood-exposure-on-push-out-bond-strength-of-four-calcium-silicate-based-cements
#7
Kazem Ashofteh Yazdi, Behnam Bolhari, Tohid Sabetmoghaddam, Naghmeh Meraji, Mohammad Javad Kharazifard
INTRODUCTION: The purpose of this study was to compare the push-out bond strength of white ProRoot Mineral Trioxide Aggregate (MTA), Biodentine, calcium-enriched mixture (CEM) cement and Endosequence Root Repair Material (ERRM) putty after exposure to blood. METHODS AND MATERIALS: A total of 96 root dentin slices with a standardized thickness of 1.00±0.05 mm and standardized canal spaces were randomly divided into 4 main experimental groups (n=24) according to the calcium silicate based cement (CSC) used: white ProRoot MTA, CEM Cement, ERRM Putty and Biodentine...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28508711/surface-sensing-and-stress-signalling-in-ulva-and-fouling-diatoms-potential-targets-for-antifouling-a-review
#8
Stephanie E M Thompson, Juliet C Coates
Understanding the underlying signalling pathways that enable fouling algae to sense and respond to surfaces is essential in the design of environmentally friendly coatings. Both the green alga Ulva and diverse diatoms are important ecologically and economically as they are persistent biofoulers. Ulva spores exhibit rapid secretion, allowing them to adhere quickly and permanently to a ship, whilst diatoms secrete an abundance of extracellular polymeric substances (EPS), which are highly adaptable to different environmental conditions...
May 2017: Biofouling
https://www.readbyqxmd.com/read/28506642/no-waiting-dentine-self-etch-concept-merit-or-hype
#9
Xue-Qing Huang, César R Pucci, Tao Luo, Lorenzo Breschi, David H Pashley, Li-Na Niu, Franklin R Tay
OBJECTIVE: A recently-launched universal adhesive, G-Premio Bond, provides clinicians with the alternative to use the self-etch technique for bonding to dentine without waiting for the adhesive to interact with the bonding substrate (no-waiting self-etch; Japanese brochure), or after leaving the adhesive undisturbed for 10s (10-s self-etch; international brochure). The present study was performed to examine in vitro performance of this new universal adhesive bonded to human coronal dentine using the two alternative self-etch modes...
May 12, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28503474/bonding-of-the-silane-containing-multi-mode-universal-adhesive-for-lithium-disilicate-ceramics
#10
Hyun-Young Lee, Geum-Jun Han, Juhea Chang, Ho-Hyun Son
OBJECTIVES: This study evaluated the influence of a multi-mode universal adhesive (MUA) containing silane (Single Bond Universal, 3M EPSE) on the bonding of resin cement to lithium disilicate. MATERIALS AND METHODS: Thirty IPS e.max CAD specimens (Ivoclar Vivadent) were fabricated. The surfaces were treated as follows: Group A, adhesive that did not contain silane (ANS, Porcelain Bonding Resin, Bisco); Group B, silane (S) and ANS; Group C, hydrofluoric acid (HF), S, and ANS; Group D, MUA; Group E, HF and MUA...
May 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28498267/endoscopic-infracochlear-approach-for-drainage-of-petrous-apex-cholesterol-granulomas-a-case-series
#11
Cameron C Wick, Alexander R Hansen, Joe Walter Kutz, Brandon Isaacson
OBJECTIVE: To describe the feasibility and technical nuances of a transcanal endoscopic infracochlear approach for drainage of petrous apex cholesterol granulomas. STUDY DESIGN: Retrospective case review. SETTING: Tertiary care university hospital. PATIENTS: A 32-year-old man with bilateral petrous apex cholesterol granulomas and a 54-year-old man with a left-sided petrous apex granuloma each with symptoms necessitating surgical intervention...
May 11, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28492752/effect-of-metal-primers-on-bond-strength-of-a-composite-resin-to-nickel-chrome-metal-alloy
#12
Gabriel Nima, Paulo Vitor Campos Ferreira, Andreia Bolzan de Paula, Simonides Consani, Marcelo Giannini
This study evaluated the effects of three metal primers and one multi-mode adhesive system on the shear bond strength (SBS) of a flowable composite resin to nickel-chrome metal alloy (Ni-Cr). Ninety plates were cast from Ni-Cr and divided in nine groups (n=10). The surfaces were sandblasted with Al2O3 and primed with three adhesive primers: Alloy Primer (AP), Universal Primer (TP) and RelyX Ceramic Primer (CP), and a multi-mode adhesive (Scotchbond Universal, SU). The Adper Single Bond Plus (SB) and SU adhesives were also combined with adhesive primers...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28488772/active-application-of-primer-acid-on-acid-treated-enamel-influence-on-the-bond-effectiveness-of-self-etch-adhesives-systems
#13
Cíntia Tereza Pimenta Araújo, Lúcia Trazzi Prieto, Daiane Cristianismo Costa, Mariana Avalone Bosso, Erick Kamiya Coppini, Carlos Tadeu Santos Dias, Luis Alexandre Maffei Sartini Paulillo
AIM: Evaluate the composite-to-enamel bond after passive or active application of self-etching primer systems on polished or pre-etched enamel with phosphoric acid. MATERIALS AND METHODS: Two self-etch adhesives systems (SEAS) were used: Clearfil SE Bond and Easy Bond. Third human molars were divided into 8 groups (N = 10). The crown of each tooth was sectioned into halves and the mesial/distal surfaces were used. The adhesives were actively or passively applied on enamel with or without prior phosphoric-acid etching...
May 10, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28487037/effect-of-self-curing-activators-and-curing-protocols-on-adhesive-properties-of-universal-adhesives-bonded-to-dual-cured-composites
#14
Mario Felipe Gutiérrez, Elisama Sutil, Pâmela Malaquias, Thalita de Paris Matos, Lucas Marques de Souza, Alessandra Reis, Jorge Perdigão, Alessandro D Loguercio
OBJECTIVES: To measure microshear bond strength (μSBS) and nanoleakage (NL) of self-etch universal adhesives under core buildup restorations using different curing protocols, at 24h and after 6-month water storage. METHODS: Middle dentin of 55 molars was divided into: Clearfil Universal Bond [CFU], Prime&Bond Elect [PBE], and One Coat 7 Universal [OCU]. All-Bond Universal [ABU] and Clearfil SE Bond [CSE] were used as control. CFU, PBE and OCU were: light-cured [LC], dual-cured [DC] and self-cured [SC]...
May 6, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28483506/laparoscopic-repair-of-a-symptomatic-post-cesarean%C3%A2-section-isthmocele-a-video-case-report
#15
Giorgio Aimi, Laura Buggio, Nicola Berlanda, Paolo Vercellini
OBJECTIVE: To describe our technique for laparoscopic management of post-cesarean section isthmocele. DESIGN: Surgical video article. Local Institutional Review Board approval for the video reproduction has been obtained. SETTING: University hospital. PATIENT(S): A 36-year-old patient with a history of two previous cesarean deliveries. She complained of persistent postmenstrual spotting and chronic pelvic pain. At transvaginal ultrasound examination, a cesarean scar defect of 20...
May 5, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28478897/one-stage-surgical-treatment-for-concomitant-rotator-cuff-tears-with-shoulder-stiffness-has-comparable-results-with-isolated-rotator-cuff-tears-a-systematic-review
#16
REVIEW
Soheil Sabzevari, Amir Reza Kachooei, Juan Giugale, Albert Lin
BACKGROUND: Addressing preoperative shoulder stiffness before rotator cuff repair (RCR) is advocated, but the effectiveness of this approach is debatable. We hypothesized that 1-stage treatment of concomitant rotator cuff tear (RCT) with shoulder stiffness has comparable results with isolated RCT. METHODS: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the databases including MEDLINE, Embase, Cochrane Library, and Scopus were searched using the keywords of "shoulder stiffness" OR "adhesive capsulitis" OR "frozen shoulder" AND "rotator cuff...
May 3, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28468685/a-neglected-risk-for-sparganosis-eating-live-tadpoles-in-central-china
#17
Jing Cui, Ye Wang, Xi Zhang, Xi-Meng Lin, Hong-Wei Zhang, Zhong-Quan Wang, Jia-Xu Chen
A 29-year-old farmer from central China was sent into the Emergency Department of the Affiliated Hospital of Zhengzhou University. He had a 15-day history of persistent high fever, abdominal distention and pain. The patient was clinically diagnosed as appendicitis and peritonitis, and treated with antibiotics in a local hospital, did not improve. On exploratory laparotomy, the appendicular perforation and peritonitis were seen; appendicectomy were performed, and antibiotics were given. However, high fever and abdominal pain still persisted; intestinal adhesion and obstruction, ascites appeared...
May 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28468322/virus-like-particle-vlp-plus-microcrystalline-tyrosine-mct-adjuvants-enhance-vaccine-efficacy-improving-t-and-b-cell-immunogenicity-and-protection-against-plasmodium-berghei-vivax
#18
Gustavo Cabral-Miranda, Matthew D Heath, Mona O Mohsen, Ariane C Gomes, Paul Engeroff, Amy Flaxman, Fabiana M S Leoratti, Aadil El-Turabi, Arturo Reyes-Sandoval, Murray A Skinner, Matthias F Kramer, Martin F Bachmann
Vaccination is the most effective prophylactic tool against infectious diseases. Despite continued efforts to control malaria, the disease still generally represents a significant unmet medical need. Microcrystalline tyrosine (MCT) is a well described depot used in licensed allergy immunotherapy products and in clinical development. However, its proof of concept in prophylactic vaccines has only recently been explored. MCT has never been used in combination with virus-like particles (VLPs), which are considered to be one of the most potent inducers of cellular and humoral immune responses in mice and humans...
May 2, 2017: Vaccines
https://www.readbyqxmd.com/read/28467265/bonding-polycrystalline-zirconia-with-10-mdp-containing-adhesives
#19
A E Llerena-Icochea, R M Costa, Afs Borges, Jfs Bombonatti, A Y Furuse
OBJECTIVE: The objective of this study was to evaluate the influence of adhesives with different 10-MDP concentrations on the shear bond strength of a resin cement to zirconia. METHODS AND MATERIALS: Six experimental adhesives were prepared with the following composition: camphorquinone, 1,2-diaminobenzene, butylhydroxytoluene, diphenyliodonium hexafluorophosphate, 2-hydroxyethyl methacrylate triethylene glycol dimethacrylate, ethoxylated bisphenol A glycol dimethacrylate, urethane dimethacrylate, bisphenol A diglycidyl methacrylate, and ethanol...
May 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28467258/effect-of-endocrown-pulp-chamber-extension-depth-on-molar-fracture-resistance
#20
A Hayes, N Duvall, M Wajdowicz, H Roberts
PURPOSE: The purpose of this study was to evaluate the effect of endocrown pulp chamber extension on mandibular molar fracture resistance. METHODS AND MATERIALS: A total of 36 recently extracted mandibular third molars of approximate equal size were sectioned at the facial lingual height of contour followed by endodontic access into the pulp chamber. The specimens were then randomly divided into three groups (n=12) and pulpal and root canal contents removed. Pulp chamber floors were established at 2, 3, and 4 mm from the occlusal table using a three-step etch-and-rinse adhesive and a flowable resin composite...
May 2017: Operative Dentistry
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