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https://www.readbyqxmd.com/read/27913545/what-have-we-learned-from-large-population-studies-of-von-willebrand-disease
#1
Robert R Montgomery, Veronica H Flood
Von Willebrand factor (VWF) is a critical regulator of hemostatic processes, including collagen binding, platelet adhesion, and platelet aggregation. It also serves as a carrier protein to normalize plasma factor VIII synthesis, release, and survival. While VWF protein measurements by immunoassay are reasonably comparable between institutions, the measurement of VWF ristocetin cofactor activity (VWF:RCo) has significant variability. Other tests of VWF function, including collagen binding or platelet glycoprotein IIb-IIIa binding, are not universally available, yet these functional defects may cause major bleeding even with normal VWF antigen (VWF:Ag) and VWF:RCo assays...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27900989/negative-association-of-circulating-microrna-126-with-high-sensitive-c-reactive-protein-and-vascular-cell-adhesion-molecule-1-in-patients-with-coronary-artery-disease-following-percutaneous-coronary-intervention
#2
Jun-Nan Wang, You-You Yan, Zi-Yuan Guo, Ya-Juan Jiang, Lu-Lu Liu, Bin Liu
BACKGROUND: Percutaneous coronary intervention (PCI) causes endothelial damage, resulting in an inflammatory response with elevation of markers such as high-sensitive C-reactive protein (hs-CRP) and vascular cell adhesion molecule-1 (VCAM-1), which are associated with restenosis after PCI. Evidence suggests that microRNA-126 (miR-126) plays an important role in vascular inflammation, but its correlation with PCI-mediated inflammation has not been investigated. In this study, we investigated the effect of PCI on circulating miR-126 and inflammation markers such as hs-CRP and VCAM-1...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27896210/comparison-of-the-bonding-strengths-of-second-and-third-generation-light-emitting-diode-light-curing-units
#3
Hee-Min Lee, Sang-Cheol Kim, Kyung-Hwa Kang, Na-Young Chang
OBJECTIVE: With the introduction of third-generation light-emitting diodes (LEDs) in dental practice, it is necessary to compare their bracket-bonding effects, safety, and efficacy with those of the second-generation units. METHODS: In this study, 80 extracted human premolars were randomly divided into eight groups of 10 samples each. Metal or polycrystalline ceramic brackets were bonded on the teeth using second- or third-generation LED light-curing units (LCUs), according to the manufacturers' instructions...
November 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27895635/molecular-characteristic-and-virulence-gene-profiles-of-community-associated-methicillin-resistant-staphylococcus-aureus-isolates-from-pediatric-patients-in-shanghai-china
#4
Xing Wang, Xia Li, Wei Liu, Weichun Huang, Qihua Fu, Min Li
Staphylococcus aureus is a globally important human pathogen, especially among children and immunocompromised patients. The emergence and spread of community-associated methicillin-resistant S. aureus (CA-MRSA) has become a serious public health problem worldwide. The aim of this study was to investigate the prevalence, molecular characteristics and virulence profiles of CA-MRSA infections from pediatric patients in a university hospital in Shanghai, China. A total of 80 CA-MRSA isolates were collected from July 2012 to December 2013 in Shanghai Children's Medical Center and analyzed by multilocus sequence typing, staphylococcus chromosomal cassette mec (SCCmec) typing, and spa typing...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27891467/an-in-vitro-comparative-study-of-shear-bond-strength-of-composite-resin-to-bleached-enamel-using-three-herbal-antioxidants
#5
Pratap Kumar Mukka, Nanda Kumar Komineni, Sambashivarao Pola, E Soujanya, Anand Ramtheerth Karne, Bhasker Nenavath, Sandeep Shiva, Pallavi Vuppunuthula
INTRODUCTION: If adhesive restorations are carried out imme-diately, the Shear Bond Strength (SBS) to bleached enamel is reduced. The use of antioxidants can be highlighted since it seems to be a more effective alternative to reduce or remove the residual oxygen and immediate improvement in SBS. AIM: The purpose of this in-vitro study was an attempt to regain the lost bond strength, for which, the comparison of SBS of composite resin to bleached enamel was carried out using various antioxidants i...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27880028/effect-of-different-surface-treatments-on-bond-strength-of-resin-cement-to-a-cad-cam-restorative-material
#6
Kubilay Barutcigil, Çağatay Barutcigil, Esra Kul, Mehmet Mustafa Özarslan, Ulviye Sebnem Buyukkaplan
PURPOSE: To investigate the effects of various surface treatment methods on the shear bond strength of self-adhesive resin cement to a novel CAD/CAM hybrid ceramic material. MATERIALS AND METHODS: A novel hybrid ceramic restorative material (Vita Enamic) was used in this study. Sixty resin block specimens were prepared and separated into six groups for each surface treatment method (n = 10); group 1: control group, no treatment applied; group 2: sandblasted by 30 μm silicate-coated alumina particles (CoJet Sandblasting); group 3: 50 μm Al2 O3 sandblasting; group 4: 10% hydrofluoric acid; group 5: no surface treatment + universal adhesive (3M Single Bond Universal); group 6: 200 mJ, 10 Hz 2W Er,Cr:YSGG laser treatment...
November 23, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/27878896/bonding-performance-of-universal-adhesives-to-er-cr-ysgg-laser-irradiated-enamel
#7
Muhammet Kerim Ayar, Fatih Erdemir
Universal adhesives have been recently introduced for use as self-etch or etch-and-rinse adhesives depending on the dental substrate and clinical condition. However, their bonding effectiveness to laser-irradiated enamel is still not well-known. Thus, the aim of this study was to compare the shear bond strength (SBS) of universal adhesives (Single Bond Universal; Nova Compo-B Plus) applied to Er,Cr:YSGG laser-irradiated enamel with SBS of the same adhesives applied in self-etch and acid-etching modes, respectively...
November 23, 2016: Microscopy Research and Technique
https://www.readbyqxmd.com/read/27871482/push-out-bond-strength-of-fiber-posts-to-intraradicular-dentin-using-multimode-adhesive-system
#8
Siavash Savadi Oskoee, Mahmoud Bahari, Soodabeh Kimyai, Saeed Asgary, Katayoun Katebi
INTRODUCTION: Because there is little information about bond strength of fiber posts cemented with a universal adhesive system (UAS) with different resin cements, the aim of this study was to compare the effect of different bonding strategies in the application of UASs on push-out bond strength of fiber posts to intraradicular dentin. METHODS: Seventy-two single-rooted teeth were randomly divided into 6 groups: self-adhesive resin cement (SAC), dual-cure resin cement (DCC), UAS in the etch-and-rinse (E&R) mode and SAC (E&R + SAC), UAS in the self-etch (SE) mode and SAC (SE + SAC), UAS in the E&R mode and DCC (E&R + DCC), and UAS in the SE mode and DCC (SE + DCC)...
December 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27870587/17%C3%AE-estradiol-enhances-vascular-endothelial-ets-1-mir-126-3p-expression-the-possible-mechanism-for-attenuation-of-atherosclerosis
#9
Ping Li, Jinzhi Wei, Xiaosa Li, Yang Cheng, Weiyu Chen, Yuhong Cui, Tommaso Simoncini, Zhengtian Gu, Jun Yang, Xiaodong Fu
CONTEXT: Endothelial microRNA 126 (miR-126) attenuates the development of atherosclerosis (AS). However, there is no evidence showing the role of miR-126 in estrogen's anti-atherogenic effects. OBJECTIVE: We hypothesized that 17β-estradiol (E2) modulates miR-126 expression, thus may improve endothelial function and retard AS development. DESIGN/SETTING/PARTICIPANTS: This was a prospective cohort study of 12 healthy regularly menstruating female volunteers aged 23-26 yr conducted at Guangzhou Medical University...
November 21, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27867479/donor-pretreatment-with-carbon-monoxide-prevents-ischemia-reperfusion-injury-following-heart-transplantation-in-rats
#10
Noritomo Fujisaki, Keisuke Kohama, Takeshi Nishimura, Hayato Yamashita, Michiko Ishikawa, Akihiro Kanematsu, Taihei Yamada, Sungsoo Lee, Tetsuya Yumoto, Kohei Tsukahara, Joji Kotani, Atsunori Nakao
Because inhaled carbon monoxide (CO) provides potent anti-inflammatory and antioxidant effects against ischemia reperfusion injury, we hypothesized that treatment of organ donors with inhaled CO would decrease graft injury after heart transplantation. Hearts were heterotopically transplanted into syngeneic Lewis rats after 8 hours of cold preservation in University of Wisconsin solution. Donor rats were exposed to CO at a concentration of 250 parts per million for 24 hours via a gas-exposure chamber. Severity of myocardial injury was determined by total serum creatine phosphokinase and troponin I levels at three hours after reperfusion...
July 2016: Medical Gas Research
https://www.readbyqxmd.com/read/27863859/effect-of-fiber-posts-on-the-fracture-resistance-of-maxillary-central-incisors-with-class-iii-restorations-an-in%C3%A2-vitro-study
#11
Mohammed Abduljawad, Abdulaziz Samran, Jadalkareem Kadour, Wassim Karzoun, Matthias Kern
STATEMENT OF PROBLEM: Endodontically treated teeth with Class III restorations show reduced fracture resistance. The placement of glass fiber posts may affect fracture resistance and should be further evaluated. PURPOSE: The purpose of this in vitro study was to evaluate the effect of fiber posts on the fracture resistance of endodontically treated maxillary central incisors with Class III restorations. MATERIAL AND METHODS: Forty extracted human maxillary central incisors were selected and divided into 4 test groups (n=10 each) according to the restoration strategy: control group; endodontically treated teeth without endodontic posts (GHT); endodontically treated teeth with 2 Class III restorations simulating coronal destruction (GCT); endodontically treated teeth with 2 Class III restorations and a carbon fiber post (GCF); and endodontically treated teeth with 2 Class III restorations and a glass-fiber post (GGF)...
November 15, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27856386/reproductive-outcome-in-patients-with-intrauterine-adhesions-following-hysteroscopic-adhesiolysis-experience-from-the-largest-women-s-hospital-in-china
#12
Limei Chen, Hongwei Zhang, Qing Wang, Feng Xie, Shujun Gao, Yu Song, Jing Dong, Hua Feng, Kangyun Xie, Long Sui
STUDY OBJECTIVE: To analyze the reproductive outcome of hysteroscopic adhesiolysis and assess the diagnostic accuracy of transvaginal ultrasonography (TVS) in infertile women resulting from intrauterine adhesions (IUAs) DESIGN: Retrospective , cross-sectional study (Canadian Task Force classification II-2). SETTING: University tertiary referral center PATIENTS: Three hundred and fifty seven patients with mild, moderate, and severe IUAs underwent hysteroscopic adhesiolysis between January 2012 and December 2015 INTERVENTIONS: Hysteroscopic adhesiolysis in the outpatient analgesic setting for infertility and IUAs...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27845030/capsule-preserving-hydrodilatation-with-corticosteroid-versus-corticosteroid-injection-alone-in-refractory-adhesive-capsulitis-of-shoulder-a-randomized-controlled-trial
#13
Doo-Hyung Lee, Seung-Hyun Yoon, Michael Young Lee, Kyu-Sung Kwack, Ueon Woo Rah
OBJECTIVE: To determine whether capsule-preserved hydrodilatation with corticosteroid (CPHC) improves pain and function in patients with refractory adhesive capsulitis (AC) better than intra-articular corticosteroid injection (IACI) alone. DESIGN: Prospective randomized controlled study. SETTING: University-affiliated tertiary care hospital. PARTICIPANTS: Primary AC subjects (N=64) with shoulder pain level of visual analogue scale (VAS) ≥ 5 even after the initial administration of IACI alone...
November 11, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27843887/comparative-evaluation-and-influence-on-shear-bond-strength-of-incorporating-silver-zinc-oxide-and-titanium-dioxide-nanoparticles-in-orthodontic-adhesive
#14
Aileni Kaladhar Reddy, Prabhuraj B Kambalyal, Santosh R Patil, Mallikarjun Vankhre, Mohammed Yaser Ahmed Khan, Thamtam Ramana Kumar
OBJECTIVE: To investigate the influence of silver (Ag), zinc oxide (ZnO), and titanium dioxide (TiO2) nanoparticles on shear bond strength (SBS). MATERIALS AND METHODS: One hundred and twenty extracted premolars divided into four groups with thirty specimens in each group. Group 1 (control): brackets (American Orthodontics) were bonded with Transbond XT primer. Groups 2, 3, and 4: brackets (American Orthodontics) were bonded with adhesives incorporated with Ag, ZnO, and TiO2 nanoparticles in the concentration of 1...
October 2016: Journal of Orthodontic Science
https://www.readbyqxmd.com/read/27843249/in-vitro-evaluation-of-stainless-steel-crowns-cemented-with-resin-modified-glass-ionomer-and-two-new-self-adhesive-resin-cements
#15
REVIEW
Sidhant Pathak, K K Shashibhushan, P Poornima, Vv Subba Reddy
AIMS: To assess and compare the retentive strength of two dual-polymerized self-adhesive resin cements (RelyX U200, 3M ESPE & SmartCem2, Dentsply Caulk) and a resin-modified glass ionomer cement (RMGIC; RelyX Luting 2, 3M ESPE) on stainless steel crown (SSC). MATERIALS AND METHODS: Thirty extracted teeth were mounted on cold cured acrylic resin blocks exposing the crown till the cemento-enamel junction. Pretrimmed, precontoured SSC was selected for a particular tooth...
July 2016: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27842516/comparative-genomic-analysis-of-the-flagellin-glycosylation-island-of-the-gram-positive-thermophile-geobacillus
#16
Pieter De Maayer, Don A Cowan
BACKGROUND: Protein glycosylation involves the post-translational attachment of sugar chains to target proteins and has been observed in all three domains of life. Post-translational glycosylation of flagellin, the main structural protein of the flagellum, is a common characteristic among many Gram-negative bacteria and Archaea. Several distinct functions have been ascribed to flagellin glycosylation, including stabilisation and maintenance of the flagellar filament, motility, surface recognition, adhesion, and virulence...
November 14, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27836148/volumetric-shrinkage-and-film-thickness-of-cementation-materials-for-veneers-an-in%C3%A2-vitro-3d-microcomputed-tomography-analysis
#17
Camila S Sampaio, João Malta Barbosa, Eduardo Cáceres, Lindiane C Rigo, Paulo G Coelho, Estevam A Bonfante, Ronaldo Hirata
STATEMENT OF PROBLEM: Few studies have investigated the volumetric polymerization shrinkage and film thickness of the different cementation techniques used to cement veneers. PURPOSE: The purpose of this in vitro study was to evaluate the volumetric polymerization shrinkage (VS) and film thickness (FT) of various cementation techniques through 3-dimensional (3D) microcomputed tomography (μCT). MATERIAL AND METHODS: Forty-eight artificial plastic maxillary central incisors with standard preparations for veneers were provided by a mannequin manufacturer (P-Oclusal) and used as testing models with the manufacturer's plastic veneers...
November 8, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27834412/effect-of-sonic-application-of-universal-adhesive-systems-on-bond-strength-of-fiber-posts-to-root-canal
#18
Driellen C Zarpellon, Anna L Szesz, Alessandro D Loguercio, Cesar A G Arrais
PURPOSE: This study evaluated the push-out bond strength (BS) of fiber posts in root canals and the nanoleakage (NL) pattern at the bonding interface when universal adhesives were applied in etch-and-rinse mode to root dentin using an oscillating sonic device. MATERIALS AND METHODS: Fifty-four roots of human premolars were endodontically prepared and divided into 6 experimental groups according to the main factors: adhesive system/resin cement (Ambar Universal/AllCem, Scotchbond Universal/RelyX ARC, Prime&Bond Elect/Enforce) and application mode (vigorous manual or sonic)...
November 10, 2016: Journal of Adhesive Dentistry
https://www.readbyqxmd.com/read/27829765/comparative-study-on-the-tensile-bond-strength-and-marginal-fit-of-complete-veneer-cast-metal-crowns-using-various-luting-agents-an-in-vitro-study
#19
B Devi Parameswari, M Rajakumar, G Lambodaran, Shyam Sundar
INTRODUCTION: Several commercially available luting agents are used to cement the dental restorations such as intra-coronal, extra-coronal, and fixed partial dentures. Tensile bond strength (TBS) and accurate marginal fit are the essential factors to determine the good clinical results in fixed prosthesis. The retentivity of the luting cements is assessed by their adhesive capacity over the tooth surface and metal surface. Generally, the adhesive ability has been evaluated with in vitro testing, with tensile bond tests...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27826391/effect-of-gluma-desensitizer-on-the-retention-of-full-metal-crowns-cemented-with-rely-x-u200-self-adhesive-cement
#20
Shirin Lawaf, Ezatallah Jalalian, Roshanak Roshan, Arash Azizi
PURPOSE: Considering the importance of retention in the success and long-term clinical service of fixed partial dentures (FPDs) as well as the existing controversy regarding the effect of GLUMA desensitizer on the retention of full metal crowns cemented with RelyX U200 self-adhesive cement, this study aimed to assess the effect of GLUMA desensitizer on the retention of full metal crowns cemented using RelyX U200. MATERIALS AND METHODS: In this experimental study, 20 sound human premolars were prepared; a 0...
October 2016: Journal of Advanced Prosthodontics
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