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https://www.readbyqxmd.com/read/28451481/rare-complications-of-cervical-spine-surgery-pseudomeningocoele
#1
Tamir Ailon, Justin S Smith, Ahmad Nassr, Zachary A Smith, Wellington K Hsu, Michael G Fehlings, David E Fish, Jeffrey C Wang, Alan S Hilibrand, Praveen V Mummaneni, Dean Chou, Rick C Sasso, Vincent C Traynelis, Paul M Arnold, Thomas E Mroz, Zorica Buser, Elizabeth L Lord, Eric M Massicotte, Arjun S Sebastian, Khoi D Than, Michael P Steinmetz, Gabriel A Smith, Jonathan Pace, Mark Corriveau, Sungho Lee, K Daniel Riew, Christopher Shaffrey
STUDY DESIGN: This study was a retrospective, multicenter cohort study. OBJECTIVES: Rare complications of cervical spine surgery are inherently difficult to investigate. Pseudomeningocoele (PMC), an abnormal collection of cerebrospinal fluid that communicates with the subarachnoid space, is one such complication. In order to evaluate and better understand the incidence, presentation, treatment, and outcome of PMC following cervical spine surgery, we conducted a multicenter study to pool our collective experience...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28450150/late-mitral-restenosis-after-percutaneous-commissurotomy-predictive-value-of-inflammation-and-extracellular-matrix-remodeling-biomarkers
#2
Rachid Mechmeche, Amira Zaroui, Sonia Aloui, Marouane Boukhris, Monia Allal-Elasmi, Naziha Kaabachi, Bechir Zouari
BACKGROUND: The role of chronic inflammation in mitral restenosis after percutaneous mitral commissurotomy (PMC) is still controversial. AIMS: We sought to assess the predictive value of inflammation and extracellular matrix (ECM) remodeling biomarkers in late mitral restenosis after PMC. METHODS: We prospectively enrolled 155 patients (mean age 46.2±11 years) with at least 5 year follow up after primary PMC. Serum levels of high sensitive C-Reactive Protein (hs-CRP), matrix metalloproteinases MMPs, tissue-specific inhibitors of matrix metalloproteinases TIMPs, and tumor necrosis factor α (TNFα)] were measured...
April 24, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28447222/feeding-strategies-in-pediatric-cancer-patients-with-gastrointestinal-mucositis-a-multicenter-prospective-observational-study-and-international-survey
#3
Nicoline S S Kuiken, Edmond H H M Rings, Marry M van den Heuvel-Eibrink, Marianne D van de Wetering, Wim J E Tissing
INTRODUCTION: Currently, there is no adequate prevention or treatment for both oral and gastrointestinal mucositis induced by chemotherapy and/or radiotherapy. Supportive care of symptoms plays a primary role during mucositis in the pediatric clinical setting. We aimed to get insight in the currently used feeding strategies in clinical practice in pediatric cancer patients with chemotherapy-induced mucositis. METHODS: A prospective observational study was performed to identify feeding strategies after chemotherapy courses causing mucositis in almost all patients at the University Medical Center Groningen (UMCG), the Academic Medical Center Amsterdam (AMC), and the Princess Maxima Center Utrecht (PMC)...
April 26, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28445076/image-based-phenotypic-screening-with-human-primary-t-cells-using-one-dimensional-imaging-cytometry-with-self-tuning-statistical-gating-algorithms
#4
Steve S Wang, Daniel J Ehrlich
The parallel microfluidic cytometer (PMC) is an imaging flow cytometer that operates on statistical analysis of low-pixel-count, one-dimensional (1D) line scans. It is highly efficient in data collection and operates on suspension cells. In this article, we present a supervised automated pipeline for the PMC that minimizes operator intervention by incorporating multivariate logistic regression for data scoring. We test the self-tuning statistical algorithms in a human primary T-cell activation assay in flow using nuclear factor of activated T cells (NFAT) translocation as a readout and readily achieve an average Z' of 0...
April 1, 2017: SLAS Discovery
https://www.readbyqxmd.com/read/28441683/geometric-torsion-in-adolescent-idiopathic-scoliosis-a-new-method-to-differentiate-between-lenke-1-subtypes
#5
Jesse Shen, Samuel Kadoury, Hubert Labelle, Marjolaine Roy-Beaudry, Carl-Éric Aubin, Stefan Parent
STUDY DESIGN: Consecutive case series. OBJECTIVE: To study geometric torsion in thoracic adolescent idiopathic scoliosis (AIS) to propose it as a numerical three-dimensional (3D) parameter that quantifies the scoliosis deformity. SUMMARY OF BACKGROUND DATA: AIS is a 3D deformity of the spine. The most widely accepted and used classification systems, however, still rely on two-dimensional aspects of x-rays. Yet, a 3D classification of AIS remains elusive because there is no widely accepted 3D parameter in the clinical practice...
May 1, 2017: Spine
https://www.readbyqxmd.com/read/28432538/superoxide-generated-in-the-chloroplast-stroma-causes-photoinhibition-of-photosystem-i-in-the-shade-establishing-tree-species-psychotria-henryi
#6
Wei Huang, Ying-Jie Yang, Jiao-Lin Zhang, Hong Hu, Shi-Bao Zhang
Our previous studies indicated that high light induced significant photoinhibition of photosystem I (PSI) in the shade-establishing tree species Psychotria henryi. However, the underlying mechanism has not been fully clarified. In the present study, in order to investigate the mechanism of PSI photoinhibition in P. henryi, we treated detached leaves with constant high light in the presence of methyl viologen (MV) or a soluble α-tocopherol analog, 2,2,5,7,8-pentamethyl-6-chromanol (PMC). We found that MV significantly depressed photochemical quantum yields in PSI and PSII when compared to PMC...
April 21, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28410959/the-involvement-of-bdnf-creb-signaling-pathways-in-the-pharmacological-mechanism-of-combined-ssri-antipsychotic-treatment-in-schizophrenia
#7
Reef Einoch, Orly Weinreb, Nina Mandiuk, Moussa B H Youdim, Warren Bilker, Henry Silver
Previous studies into the mechanism of SSRI-antipsychotic synergism in our laboratory identified unique changes in the brain, particularly in the γ-aminobutyric acid (GABA)-A receptor and its modulators. This study examined the role of brain derived neurotrophic factor (BDNF)-cAMP response element binding (CREB) protein signaling pathways, including protein kinase B (AKT), glycogen synthase kinase (GSK)-3β and related molecules in the molecular response to haloperidol, fluvoxamine, combined haloperidol+fluvoxamine and clozapine treatments in rat frontal cortex, hippocampus and primary cortical neuronal cultures...
April 11, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28408690/draft-genome-sequences-of-tetragenococcus-muriaticus-strains-3mr10-3-and-pmc-11-5-isolated-from-thai-fish-sauce-during-natural-fermentation
#8
Chokchai Chuea-Nongthon, Sureelak Rodtong, Jirawat Yongsawatdigul, James L Steele
Tetragenococcus muriaticus strains 3MR10-3 and PMC-11-5 are homofermentative halophilic lactic acid bacteria isolated from Thai fish sauce during natural fermentation. Their draft genomes were sequenced. Our interest in these organisms is related to their impact on fish sauce flavor and their high osmotolerance.
April 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28387881/review-article-intermediate-alleles-of-huntington-s-disease-htt-gene-in-different-populations-worldwide-a-systematic-review
#9
REVIEW
T A Apolinário, C L A Paiva, L A Agostinho
Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative disorder caused by a dynamic mutation due to the expansion of CAG repeats in the HTT gene (4p16.3). The considered normal alleles have less than 27 CAG repeats. Intermediate alleles (IAs) show 27 to 35 CAG repeats and expanded alleles have more than 35 repeats. The IAs apparently have shown a normal phenotype. However, there are some reported associations between individuals that bear an IA and clinical HD signs, such as behavioral disturbs...
April 5, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28371114/perception-of-odors-and-tastes-in-autism-spectrum-disorders-a-systematic-review-of-assessments
#10
REVIEW
Mohamed A Boudjarane, Marine Grandgeorge, Rémi Marianowski, Laurent Misery, Éric Lemonnier
Olfaction and gustation are major sensory functions implied in processing environmental stimuli. Some evidences suggest that loss of olfactory function is an early biomarker for neurodegenerative disorders and atypical processing of odor and taste stimuli is present in several neurodevelopmental disorders, notably in Autism Spectrum Disorders (ASD). In this paper, we conducted a systematic review investigating the assessments of olfaction and gustation with psychophysics methods in individuals with ASD. Pubmed, PMC and Sciencedirect were scrutinized for relevant literature published from 1970 to 2015...
March 30, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28367918/a-thermostable-bilirubin-oxidizing-enzyme-from-activated-sludge-isolated-by-a-metagenomic-approach
#11
Nobutada Kimura, Yoichi Kamagata
Volume 31, no. 4, Page 435-441, 2016Page 435 Year of "Published online" is incorrect. It should be corrected as follows:incorrect: 2015correct: 2016 This correction has been completed on the electronic file of the present paper available at J-STAGE and PMC.The editorial board expresses sincere apology for the misprinting. Microbes and Environments editorial board.
2017: Microbes and Environments
https://www.readbyqxmd.com/read/28365070/clinical-outcome-of-primary-medial-collateral-ligament-posteromedial-corner-repair-with-or-without-staged-anterior-cruciate-ligament-reconstruction
#12
Vivek Pandey, Vikrant Khanna, Sandesh Madi, Anshul Tripathi, Kiran Acharya
INTRODUCTION: Medial collateral ligament (MCL) is a prime valgus stabilizer of the knee, and MCL tears are currently managed conservatively. However, posteromedial corner (PMC) injury along with MCL tear is not same as isolated MCL tear and the former is more serious injury and requires operative attention. However, literature is scarce about the management and outcome of PMC-MCL tear alongside anterior cruciate ligament (ACL) tear. The purpose of this study is to report the clinical outcome of primary repair of MCL and PMC with or without staged ACL reconstruction...
March 22, 2017: Injury
https://www.readbyqxmd.com/read/28343733/low-risk-papillary-microcarcinoma-of-the-thyroid-a-review-of-active-surveillance-trials
#13
REVIEW
Y Ito, A Miyauchi, H Oda
Papillary microcarcinoma (PMC) of the thyroid is defined as papillary thyroid carcinoma (PTC) measuring ≤1 cm. Many autopsy studies on subjects who died of non-thyroidal diseases reported latent small thyroid carcinoma in up to 5.2% of the subjects. A mass screening study for thyroid cancer in Japanese adult women detected small thyroid cancer in 3.5% of the examinees. This incidence was close to the incidence of latent thyroid cancer and more than 1000 times the prevalence of clinical thyroid cancer in Japanese women reported at that time...
March 16, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28322617/clinicians-views-on-management-and-terminology-for-papillary-thyroid-microcarcinoma-a-qualitative-study
#14
Brooke Nickel, Juan P Brito, Alexandra Barratt, Susan Jordan, Ray Moynihan, Kirsten McCaffery
BACKGROUND: There is growing acceptance that the increase in thyroid cancer incidence is in part a result of overdiagnosis of small low-risk papillary microcarcinomas (PMCs) with indolent clinical course. Although surgery is the cornerstone treatment for patients with PMCs, recent management guidelines are shifting toward inclusion of more conservative treatments such as active surveillance. There is little evidence on clinicians' experience in managing PMC patients and their attitudes toward treatment options, including their willingness to accept a nonsurgical option...
May 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28320525/reducing-indoor-air-pollutants-with-air-filtration-units-in-wood-stove-homes
#15
Marcy L McNamara, Jonathon Thornburg, Erin O Semmens, Tony J Ward, Curtis W Noonan
BACKGROUND: Biomass burning has been shown to be a major source of poor indoor air quality (IAQ) in developing and higher income countries across the world. Specifically, wood burning for cooking and heating contributes to high indoor concentrations of fine (particles with aerodynamic diameters<2.5μm; PM2.5) and coarse (particles with aerodynamic diameters <10μm and >2.5μm; PMc) particulate matter. Endotoxin, predominantly found within the coarse fraction of airborne particulate matter, is associated with proinflammatory effects and adverse outcomes among susceptible populations...
March 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28286847/protocol-adherence-in-prehospital-medical-care-provided-for-patients-with-chest-pain-and-loss-of-consciousness-a-brief-report
#16
Mostafa Mehrara, Nader Tavakoli, Marzieh Fathi, Babak Mahshidfar, Mohammad Amin Zare, Azita Asadi, Saeedeh Hosseinzadeh, Mehdi Safdarian
INTRODUCTION: Although many protocols are available in the field of the prehospital medical care (PMC), there is still a notable gap between protocol based directions and applied clinical practice. This study measures the rate of protocol adherence in PMC provided for patients with chest pain and loss of consciousness (LOC). METHOD: In this cross-sectional study, 10 educated research assistants audited the situation of provided PMC for non-traumatic chest pain and LOC patients, presenting to the emergency department of a tertiary level teaching hospital, compare to national recommendations in these regards...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28279837/relevance-of-diagnostic-investigations-in-patients-with-uveitis-retrospective-cohort-study-on-300-patients
#17
REVIEW
Jérôme Hadjadj, Agnès Dechartres, Thibaut Chapron, Manal Assala, Sawsen Salah, Bertrand Dunogué, Lucile Musset, Bruno Baudin, Matthieu Groh, Philippe Blanche, Luc Mouthon, Dominique Monnet, Claire Le Jeunne, Antoine Brézin, Benjamin Terrier
OBJECTIVE: The diagnostic workup of uveitis is a challenge due to the wide range of diagnoses and the lack of a well-codified diagnostic procedure. We aimed to evaluate the relevance of diagnostic investigations for the etiological diagnosis of uveitis. METHODS: Retrospective cohort study of patients referred for etiological diagnosis of uveitis. Uveitis related to ophthalmological diseases or occurring during the course of previously diagnosed diseases were not included...
May 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/28279581/exposure-of-in-pram-babies-to-airborne-particles-during-morning-drop-in-and-afternoon-pick-up-of-school-children
#18
Prashant Kumar, Ioar Rivas, Lovish Sachdeva
In-pram babies are more susceptible to air pollution effects, yet studies assessing their exposure are limited. We measured size-resolved particle mass (PMC; 0.25-32 μm) and number (PNC; 0.2-1 μm) concentrations on a 2.7 km route. The instruments were placed inside a baby pram. The route passed through 4 traffic intersections (TIs) and a bus stand. A total of ∼87 km road length was covered through 64 trips, made during school drop-in (morning) and pick-up (afternoon) hours. The objectives were to assess PMC and PNC exposure to in-pram babies at different route segments, understand their physicochemical characteristics and exposure differences between in-pram babies and adults carrying them...
May 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28247157/impaired-white-matter-connectivity-between-regions-containing-mirror-neurons-and-relationship-to-negative-symptoms-and-social-cognition-in-patients-with-first-episode-schizophrenia
#19
Yukiko Saito, Marek Kubicki, Inga Koerte, Tatsui Otsuka, Yogesh Rathi, Ofer Pasternak, Sylvain Bouix, Ryan Eckbo, Zora Kikinis, Christian Clemm von Hohenberg, Tomohide Roppongi, Elisabetta Del Re, Takeshi Asami, Sang-Hyuk Lee, Sarina Karmacharya, Raquelle I Mesholam-Gately, Larry J Seidman, James Levitt, Robert W McCarley, Martha E Shenton, Margaret A Niznikiewicz
In schizophrenia, abnormalities in structural connectivity between brain regions known to contain mirror neurons and their relationship to negative symptoms related to a domain of social cognition are not well understood. Diffusion tensor imaging (DTI) scans were acquired in 16 patients with first episode schizophrenia and 16 matched healthy controls. FA and Trace of the tracts interconnecting regions known to be rich in mirror neurons, i.e., anterior cingulate cortex (ACC), inferior parietal lobe (IPL) and premotor cortex (PMC) were evaluated...
February 28, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28217756/translational-gastroenterology-and-hepatology-is-now-indexed-in-pubmed-pmc-a-tremendous-step-forward
#20
(no author information available yet)
No abstract text is available yet for this article.
2017: Translational Gastroenterology and Hepatology
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