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nutritional status of patients with CKD

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https://www.readbyqxmd.com/read/29157465/dietos-a-dietary-recommender-system-for-chronic-diseases-monitoring-and-management
#1
Giuseppe Agapito, Mariadelina Simeoni, Barbara Calabrese, Ilaria Caré, Theodora Lamprinoudi, Pietro H Guzzi, Arturo Pujia, Giorgio Fuiano, Mario Cannataro
BACKGROUND AND OBJECTIVE: Use of mobile and web-based applications for diet and weight management is currently increasing. However, the impact of known apps on clinical outcomes is not well-characterized so far. Moreover, availability of food recommender systems providing high quality nutritional advices to both healthy and diet-related chronic diseases users is very limited. In addition, the potentiality of nutraceutical properties of typical regional foods for improving app utility has not been exerted to this end...
January 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29150712/unacylated-ghrelin-and-obestatin-promising-biomarkers-of-protein-energy-wasting-in-children-with-chronic-kidney-disease
#2
Alice Monzani, Michela Perrone, Flavia Prodam, Stefania Moia, Giulia Genoni, Sara Testa, Fabio Paglialonga, Anna Rapa, Gianni Bona, Giovanni Montini, Alberto Edefonti
BACKGROUND: Impairment in orexigenic/anorexigenic hormone balance may be key in the pathogenesis of protein energy wasting in children with chronic kidney disease (CKD). Measurement of ghrelin and obestatin concentrations in children with CKD would help assess the potential contribution of these hormones to uremic protein energy wasting. METHODS: This was a cross-sectional case-control study. Acylated and unacylated ghrelin and obestatin were measured in 42 children on conservative treatment (CT), 20 children on hemodialysis, 48 pediatric renal transplant (RTx) recipients and 43 controls (CTR) (mean age 11...
November 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29138677/oxidative-stress-in-hemodialysis-patients-a-review-of-the-literature
#3
REVIEW
Vassilios Liakopoulos, Stefanos Roumeliotis, Xenia Gorny, Evangelia Dounousi, Peter R Mertens
Hemodialysis (HD) patients are at high risk for all-cause mortality and cardiovascular events. In addition to traditional risk factors, excessive oxidative stress (OS) and chronic inflammation emerge as novel and major contributors to accelerated atherosclerosis and elevated mortality. OS is defined as the imbalance between antioxidant defense mechanisms and oxidant products, the latter overwhelming the former. OS appears in early stages of chronic kidney disease (CKD), advances along with worsening of renal failure, and is further exacerbated by the HD process per se...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29120366/a-low-geriatric-nutrition-risk-index-is-associated-with-progression-to-dialysis-in-patients-with-chronic-kidney-disease
#4
I-Ching Kuo, Jiun-Chi Huang, Pei-Yu Wu, Szu-Chia Chen, Jer-Ming Chang, Hung-Chun Chen
Evaluating nutritional status is crucial to detecting malnutrition in patients with chronic kidney disease (CKD). The Geriatric Nutritional Risk Index (GNRI) has been associated with overall and cardiovascular mortality in the dialysis population. The aim of this study was to evaluate whether the GNRI is associated with progression to dialysis in patients with moderate to advanced CKD. We enrolled 496 patients with stage 3-5 CKD who had received echocardiographic examinations, and categorized them according to baseline GNRI values calculated using the serum albumin level and body weight...
November 9, 2017: Nutrients
https://www.readbyqxmd.com/read/29057381/association-of-sleep-duration-symptoms-and-disorders-with-mortality-in-adults-with-chronic-kidney-disease
#5
Ana C Ricardo, Vivien Goh, Jinsong Chen, Esteban Cedillo-Couvert, Mary Kapella, Bharati Prasad, Sharmila Parvathaneni, Kristen Knutson, James P Lash
INTRODUCTION: In general populations, short and long sleep duration, poor sleep quality and sleep disorders have been associated with increased risk of death. We evaluated these associations in individuals with chronic kidney disease (CKD). METHODS: Prospective cohort study of 1,452 National Health and Nutrition Examination Survey (NHANES) 2005-2008 participants with CKD. CKD was defined by estimated glomerular filtration rate <60 ml/min/1.73m(2) or urine albumin-to-creatinine ratio ≥30 mg/g...
September 2017: KI Reports
https://www.readbyqxmd.com/read/29056169/unacylated-ghrelin-a-novel-regulator-of-muscle-intermediate-metabolism-with-potential-beneficial-effects-in-chronic-kidney-disease
#6
Gianluca Gortan Cappellari, Michela Zanetti, Pierandrea Vinci, Gianfranco Guarnieri, Rocco Barazzoni
In patients with chronic kidney disease (CKD), malnutrition with loss of skeletal muscle mass has a negative impact on morbidity and mortality. Emerging evidence indicates that a cluster of oxidative stress, inflammation, and insulin resistance directly contributes to skeletal muscle catabolism by favoring protein breakdown over synthesis. Ghrelin is a gastric hormone discovered and initially studied in its acylated orexigenic form. More recently, a role of unacylated ghrelin (UnAG) has been described to reduce skeletal muscle mitochondrial reactive oxygen species generation, inflammation, and insulin resistance both in experimental models and in clinical studies...
November 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29044338/nutritional-profile-of-hemodialysis-patients-concerning-treatment-time
#7
Livia de Almeida Alvarenga, Bárbara Danelon Andrade, Michelle Andrade Moreira, Roberto de Paula Nascimento, Isabela Dariú Macedo, Aline Silva de Aguiar
INTRODUCTION: The mortality of the population with chronic kidney disease (CKD) on hemodialysis (HD) is very high and the protein-energy malnutrition stands out as one of the most common consequences in relation to this condition. OBJECTIVE: To evaluate the association between time of hemodialysis and nutritional parameters of patients. METHODS: It is a cross-sectional study with secondary data, developed of the University Hospital of the Federal University of Juiz de Fora (HU/UFJF)...
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/28884267/diet-and-enteral-nutrition-in-patients-with-chronic-kidney-disease-not-on-dialysis-a-review-focusing-on-fat-fiber-and-protein-intake
#8
REVIEW
Alice Sabatino, Giuseppe Regolisti, Ilaria Gandolfini, Marco Delsante, Filippo Fani, Maria Cristina Gregorini, Enrico Fiaccadori
The clinical data available on dietary requirements of patients with chronic kidney disease (CKD) not on dialysis are limited and largely inconclusive in terms of the renal, cardiovascular and nutritional outcomes achievable through dietary modifications. Restriction of protein intake during the early stages of CKD may in fact slow its progression, but at the same time this approach may also lead to protein-energy wasting, if energy intake is not adequate and properly monitored. Unfortunately, compliance to dietary recommendations is traditionally low in this patient population...
September 7, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28819753/growth-hormone-treatment-improves-final-height-and-nutritional-status-of-children-with-chronic-kidney-disease-and-growth-deceleration
#9
C Bizzarri, A Lonero, M Delvecchio, L Cavallo, M F Faienza, M Giordano, L Dello Strologo, M Cappa
PURPOSE: Growth retardation is a common complication of chronic kidney disease (CKD) in children. Treatment with recombinant human growth hormone (rhGH) has been used to help short children with CKD to attain a height more in keeping with their age group, but the scientific evidence regarding the effect of rhGH on final height is scarce. METHODS: Final heights of children with CKD receiving rhGH treatment (cases) were compared with final heights of a matched cohort of children with CKD that did not receive rhGH therapy (controls)...
August 17, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28775001/characterization-and-correction-of-olfactory-deficits-in-kidney-disease
#10
Sagar U Nigwekar, Jeremy M Weiser, Sahir Kalim, Dihua Xu, Joshua L Wibecan, Sarah M Dougherty, Laurence Mercier-Lafond, Kristin M Corapi, Nwamaka D Eneanya, Eric H Holbrook, Dennis Brown, Ravi I Thadhani, Teodor G Păunescu
Patients with CKD suffer from food aversion, anorexia, and malnutrition. Although olfaction has a significant role in determining food flavor, our understanding of olfactory impairment and of the olfaction-nutrition axis in patients with kidney disease is limited. We quantified odor identification, odor threshold, and subjective odor perception in a cohort (n=161) comprising 36 participants with CKD, 100 participants with ESRD, and 25 controls. We investigated olfaction-nutrition associations in these participants and examined a novel intervention to improve olfaction in ESRD...
November 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28755901/protein-energy-wasting-syndrome-in-advanced-chronic-kidney-disease-prevalence-and-specific-clinical-characteristics
#11
Almudena Pérez-Torres, M Elena González Garcia, Belén San José-Valiente, M Auxiliadora Bajo Rubio, Olga Celadilla Diez, Ana M López-Sobaler, Rafael Selgas
INTRODUCTION: Protein-energy wasting (PEW) is associated with increased mortality and differs depending on the chronic kidney disease (CKD) stage and the dialysis technique. The prevalence in non-dialysis patients is understudied and ranges from 0 to 40.8%. OBJECTIVE: To evaluate the nutritional status of a group of Spanish advanced CKD patients by PEW criteria and subjective global assessment (SGA). PATIENTS AND METHODS: Cross-sectional study of 186 patients (101 men) with a mean age of 66...
July 26, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28745686/-effects-of-keto-amino-acids-and-a-low-protein-diet-on-the-nutritional-status-of-patients-with-stages-3b-4-chronic-kidney-disease
#12
S Yu Milovanova, Yu S Milovanov, M V Taranova, I A Dobrosmyslov
AIM: To evaluate the efficacy of keto/amino acids in maintaining protein balance and preventing mineral metabolic disturbances and the development of uremic hyperparathyroidism in the long-term use of a low-protein diet (LPD) in patients with Stages 3B-4 chronic kidney disease (CKD). SUBJECTS AND METHODS: Ninety patients with CKD caused by chronic latent glomerulonephritis in 65 patients and chronic tubulointerstitial nephritis of various etiologies (gout, drug-induced, and infection) in 25 were examined...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28675610/vitamin-d-a-modulator-of-musculoskeletal-health-in-chronic-kidney-disease
#13
REVIEW
Pablo Molina, Juan J Carrero, Jordi Bover, Philippe Chauveau, Sandro Mazzaferro, Pablo Ureña Torres
The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD), who display the combination of bone metabolism disorder, muscle wasting, and weakness. Here, we review how vitamin D represents a pathway in which bone and muscle may interact. In vitro studies have confirmed that the vitamin D receptor is present on muscle, describing the mechanisms whereby vitamin D directly affects skeletal muscle...
October 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28582807/dietary-fiber-intake-is-associated-with-chronic-kidney-disease-ckd-progression-and-cardiovascular-risk-but-not-protein-nutritional-status-in-adults-with-ckd
#14
Lu Lu, Yan-Feng Huang, Ming-Qing Wang, De-Xiu Chen, Heng Wan, Lian-Bo Wei, Wei Xiao
BACKGROUND AND OBJECTIVES: Evidence suggests that dietary fiber benefits patients with chronic kidney disease (CKD); however, this conclusion requires further validation. In this study, we examined the effects of dietary fiber on kidney function, inflammation, indoxyl sulfate, nutritional status, and cardiovascular risk in patients with advanced CKD. METHODS AND STUDY DESIGN: We performed linear regressions to assess the association between dietary fiber intake and CKD parameters...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28572892/relationship-between-chronic-kidney-disease-and-depression-in-elderly-koreans-using-the-2013-korea-national-health-and-nutrition-examination-survey-data
#15
Ji Woon Kim, Sung Jin Moon, Hyun Ja Kim, Dae Geun Lee
BACKGROUND: Depression is prevalent in patients with chronic kidney disease (CKD) and continues to increase in elderly adults. Therefore, the aim of our study was to examine the relationship between CKD and depression in older patients. METHODS: We conducted a cross-sectional study based on 2013 Korea National Health and Nutrition Examination Survey data. In total, data of 973 subjects aged ≥65 years were analyzed, and the estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration equation...
May 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/28558794/assessment-of-physical-activity-capacity-and-nutritional-status-in-elderly-peritoneal-dialysis-patients
#16
Adamasco Cupisti, Claudia D'Alessandro, Viviana Finato, Claudia Del Corso, Battista Catania, Gian Marco Caselli, Maria Francesca Egidi
BACKGROUND: This study aimed to evaluate the prevalence of sedentarism, and to assess physical capacity and nutritional status in a cohort of older patients on peritoneal dialysis (PD), with respect to age-matched non-dialysis CKD population, using highly accessible, simple methods, namely the Rapid Assessment of Physical activity (RAPA) test and the 30″ Sit-to-stand (STS) test. METHODS: This cross-sectional multicenter study included 151 renal patients older than 60 years; 71 pts...
May 30, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28553038/the-relationship-between-metabolic-acidosis-and-nutritional-parameters-in-patients-on-hemodialysis
#17
A D Sajgure, T A Dighe, J S Korpe, C B Bale, A O Sharma, N S Shinde, A A Goel, A V Mulay
The progressive loss of kidney function is accompanied by metabolic acidosis. The relationship between metabolic acidosis, nutritional status, and oral bicarbonate supplementation has not been assessed in the Indian chronic kidney disease (CKD) population who are on maintenance hemodialysis (MHD). This is a single-center prospective study conducted in the Western part of India. Thirty-five patients, who were receiving MHD were assessed for metabolic acidosis along with various nutritional parameters at the baseline and at the follow-up after 3 months, postcorrection of acidosis with oral sodium bicarbonate supplements...
May 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/28468236/non-traditional-aspects-of-renal-diets-focus-on-fiber-alkali-and-vitamin-k1-intake
#18
Adamasco Cupisti, Claudia D'Alessandro, Loreto Gesualdo, Carmela Cosola, Maurizio Gallieni, Maria Francesca Egidi, Maria Fusaro
Renal diets for advanced chronic kidney disease (CKD) are structured to achieve a lower protein, phosphate and sodium intake, while supplying adequate energy. The aim of this nutritional intervention is to prevent or correct signs, symptoms and complications of renal insufficiency, delaying the start of dialysis and preserving nutritional status. This paper focuses on three additional aspects of renal diets that can play an important role in the management of CKD patients: the vitamin K1 and fiber content, and the alkalizing potential...
April 29, 2017: Nutrients
https://www.readbyqxmd.com/read/28446125/soluble-transferrin-receptor-as-a-marker-of-erythropoiesis-in-patients-undergoing-high-flux-hemodialysis
#19
Pei Yin, Jijun Li, Yan Song
Anemia is a common complication in chronic kidney disease (CKD) patients receiving hemodialysis. The effect of high-flux dialysis (HFD) on anemia remains unclear. This prospective study aimed to evaluate the effect of HFD on anemia, and the potential of soluble transferrin receptor (sTfR) as a marker of iron status and erythropoiesis in CKD patients on hemodialysis. Forty patients, who switched from conventional low-flux dialysis to HFD for 12 months, were enrolled in this study. The levels of sTfR, hemoglobin, iron, and nutritional markers, as well as the dose of recombinant human erythropoietin (rhEPO) and use of chalybeate were determined at 0, 2, 6, and 12 months after starting HFD...
April 27, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28439567/sarcopenia-obesity-and-mortality-in-us-adults-with-and-without-chronic-kidney-disease
#20
Lagu Androga, Deep Sharma, Afolarin Amodu, Matthew K Abramowitz
INTRODUCTION: In pre-dialysis chronic kidney disease (CKD), the association of muscle mass with mortality is poorly defined, and no study has examined outcomes related to the co-occurrence of low muscle mass and excess adiposity (sarcopenic-obesity). Methods: We examined abnormalities of muscle and fat mass in adult participants of the National Health and Nutrition Examination Survey 1999-2004. We determined whether associations of body composition with all-cause mortality differed between participants with CKD compared to those without...
March 2017: KI Reports
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