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https://www.readbyqxmd.com/read/27913900/bone-mineral-density-of-extremities-is-associated-with-coronary-calcification-and-biopsy-verified-vascular-calcification-in-living-donor-renal-transplant-recipients
#1
Zhimin Chen, Jia Sun, Mathias Haarhaus, Peter Barany, Lars Wennberg, Jonaz Ripsweden, Torkel B Brismar, Bengt Lindholm, Annika Wernerson, Magnus Söderberg, Peter Stenvinkel, Abdul Rashid Qureshi
Chronic kidney disease (CKD) mineral and bone disorders (CKD-MBD) may lead to low bone mineral density (BMD) and vascular calcification (VC), but links to the latter are unclear. Here we investigated associations between BMD, coronary artery calcium (CAC) scores, and histological signs of VC in end-stage renal disease (ESRD) patients undergoing living-donor kidney transplantation (LD-Rtx). In 66 ESRD patients (median age 45 years, 68% males), BMD (by dual-energy X-ray absorptiometry, DXA), CAC score (by computed tomography, CT; n = 54), and degree of VC score (graded by histological examination of epigastric artery specimens collected at LD-Rtx; n = 55) were assessed at the time of LD-Rtx...
December 2, 2016: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/27913896/mesenchymal-stem-cells-with-enos-over-expression-enhance-cardiac-repair-in-rats-with-myocardial-infarction
#2
Leilei Chen, Yuan Zhang, Liangliang Tao, Zhijian Yang, Liansheng Wang
PURPOSE: Transplantation of mesenchymal stem cells (MSCs) is a promising therapeutic option for patients with acute myocardial infarction. METHODS: We show here that the ectopic overexpression of endothelial nitric oxide synthases (eNOS), an endothelial form of NOS, could enhance the ability of MSCs in treating ischemic heart damage after the occlusion of the coronary artery. RESULTS: Adenoviral delivery of human eNOS gene into mouse bone marrow-derived MSCs (BM-MSCs) conferred resistance to oxygen glucose deprivation (OGD)-induced cell death in vitro, and elevated the bioavailability of nitric oxide when injected into the myocardium in vivo...
December 3, 2016: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/27913628/kinect-system-in-home-based-cardiovascular-rehabilitation
#3
Ágata Vieira, Joaquim Gabriel, Cristina Melo, Jorge Machado
Cardiovascular diseases lead to a high consumption of financial resources. An important part of the recovery process is the cardiovascular rehabilitation. This study aimed to present a new cardiovascular rehabilitation system to 11 outpatients with coronary artery disease from a Hospital in Porto, Portugal, later collecting their opinions. This system is based on a virtual reality game system, using the Kinect sensor while performing an exercise protocol which is integrated in a home-based cardiovascular rehabilitation programme, with a duration of 6 months and at the maintenance phase...
December 1, 2016: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/27913564/coronary-artery-bypass-surgery-plus-medical-therapy-is-associated-with-longer-survival-over-10%C3%A2-years-than-medical-therapy-alone-in-patients-with-ischaemic-cardiomyopathy
#4
https://www.readbyqxmd.com/read/27913259/-postoperative-delayed-paradoxical-depression-pdpd-after-uncomplicated-intracranial-aneurysm-surgery
#5
Tomas Garzon-Muvdi, Wuyang Yang, Andrew S Luksik, Alejandro Ruiz-Valls, Rafael John Tamargo, Justin Caplan, Rafael J Tamargo
BACKGROUND: Postoperative delayed paradoxical depression (PDPD) is a psychiatric condition described in patients who undergo a major surgery without complications, do not have a history of mood disorders, but nevertheless become clinically depressed. PDPD has been recognized in major surgical interventions such as coronary artery bypass surgery. We sought to determine the incidence and potential factors associated with PDPD after surgical treatment of intracranial aneurysms. METHODS: The cohort of 105 patients was derived from a prospective observational dataset of 3788 consecutive cases of intracranial aneurysms accrued from 1991-2015...
November 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27913107/the-influence-of-iterative-reconstruction-on-coronary-artery-calcium-scoring-phantom-and-clinical-studies
#6
Seitaro Oda, Daisuke Utsunomiya, Takeshi Nakaura, Yoshinori Funama, Hideaki Yuki, Masafumi Kidoh, Kenichiro Hirata, Narumi Taguchi, Keiichi Honda, Hiroko Takaoka, Yuji Iyama, Kazuhiro Katahira, Katsuo Noda, Shuichi Oshima, Shinichi Tokuyasu, Yasuyuki Yamashita
RATIONALE AND OBJECTIVES: We compared the effect of iterative model reconstruction (IMR), filtered back projection (FBP), and hybrid iterative reconstruction (HIR) on coronary artery calcium (CAC) scoring. MATERIALS AND METHODS: CAC scans of 30 consecutive patients (18 men and 12 women, age 70.1 ± 12.2 years) were reconstructed with FBP, HIR, and IMR, and the image noise was measured on all images. Two radiologists independently measured the CAC scores using semiautomated software, and interobserver agreement was evaluated...
November 29, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27912733/the-effect-of-percutaneous-coronary-intervention-on-habitual-physical-activity-in-older-patients
#7
Sarah J Charman, Vincent T van Hees, Louise Quinn, Joseph R Dunford, Bilal Bawamia, Murugapathy Veerasamy, Michael I Trenell, Djordje G Jakovljevic, Vijay Kunadian
BACKGROUND: Given the ongoing burden of cardiovascular disease and an ageing population, physical activity in patients with coronary artery disease needs to be emphasized. This study assessed whether sedentary behaviour and physical activity levels differed among older patients (≥75 years) following percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) consisting of ST-segment elevation myocardial infarction (STEMI) and non STEMI (NSTEMI) versus an elective admission control group of stable angina patients...
December 3, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27912204/incremental-diagnostic-value-of-combined-quantitative-and-qualitative-parameters-of-magnetocardiography-to-detect-coronary-artery-disease
#8
Eun-Seok Shin, Yat-Yin Lam, Ae-Young Her, Johannes Brachmann, Friedrich Jung, Jai-Wun Park
BACKGROUND/OBJECTIVES: Magnetocardiography (MCG) has been proposed as a non-invasive and functional technique with high accuracy for diagnosis of myocardial ischemia. This study sought to investigate the incremental diagnostic value of combined quantitative and qualitative parameters of MCG to detect coronary artery disease (CAD). METHODS: Ninety six patients with suspected CAD who underwent coronary angiography were enrolled in the analysis to test the diagnostic accuracy of 2 MCG parameters (a quantitative parameter of the percent change of ST-segment fluctuation score and a qualitative parameter of non-dipole phenomenon)...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27912202/bioresorbable-stents-current-and-upcoming-bioresorbable-technologies
#9
REVIEW
Hui Ying Ang, Heerajnarain Bulluck, Philip Wong, Subbu S Venkatraman, Yingying Huang, Nicolas Foin
Bioresorbable scaffolds (BRS) represent a novel horizon in interventional cardiology for the treatment of coronary artery disease. The technology was introduced to overcome limitations of current metallic drug-eluting stents such as late in-stent restenosis and permanently caging the vessel. The concept of the BRS is to provide temporal support to the vessel during healing before being degraded and resorbed by the body, promoting restoration of the vessel vasomotion. Currently, there are several BRS that are under development or already commercially available...
November 12, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27912201/anxiety-levels-of-patients-undergoing-coronary-procedures-in-the-catheterization-laboratory
#10
Ronak Delewi, Wieneke Vlastra, Wim J Rohling, Tineke C Wagenaar, Max Zwemstra, Martin G Meesterman, Marije M Vis, Joanna J Wykrzykowska, Karel T Koch, Robbert J de Winter, Jan Baan, Jan J Piek, Mirjam A G Sprangers, José P S Henriques
BACKGROUND: High levels of anxiety are associated with worse outcomes in coronary artery disease patients. Little is known about anxiety levels in patients undergoing coronary procedures. Our objective is to examine the levels of anxiety in patients undergoing coronary angiography (CAG) or percutaneous coronary intervention (PCI) during the different phases of hospital stay and to evaluate which patient characteristics are associated with increased anxiety. METHODS: Patients undergoing CAG or PCI between April 2009 and April 2010 were included in this prospective cohort study...
November 11, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27912198/usefulness-of-chads2-score-for-prognostic-stratification-of-patients-with-coronary-artery-disease-a-systematic-review-and-meta-analysis-of-cohort-studies
#11
Xiaobo Zhou, Kaiwu Cao, Shuangqing Kou, Shencheng Qu, Hongling Li, Ying Yu, Cong Wang, Yu Liu, Pengying Li, Dan Li
OBJECTIVE: To evaluate the role of CHADS2 score on predicting ischaemic stroke or transient ischaemic attack (TIA) and death in patients with coronary artery disease (CAD), irrespective of the presence or absence of atrial fibrillation (AF). METHODS: We searched for cohort studies that reported risk estimates for incidence of ischaemic stroke/TIA or mortality by levels of CHADS2 score in Medline/PubMed and Embase. Random effects models were used to calculate pooled risk ratios (RRs) and 95% confidence intervals (CIs)...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27911975/transfusion-requirements-in-esrd-patients-admitted-with-gi-hemorrhage-undergoing-inpatient-endoscopy
#12
Conor McCartney, Shrihari Santosh, Setu Patolia, Sadashiv Santosh
OBJECTIVES: To date there are no studies evaluating the utilization of blood products in patients with end-stage renal disease (ESRD) with gastrointestinal (GI) hemorrhage. This study estimated transfusion needs and determined predictors available at the time of admission for patients with ESRD admitted to a university hospital with GI bleeding requiring inpatient endoscopy. METHODS: A retrospective chart review was performed on all patients with ESRD who underwent inpatient endoscopy for suspected GI bleeding between 2009 and 2015...
December 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27911394/confirmation-of-myocardial-ischemia-and-reperfusion-injury-in-mice-using-surface-pad-electrocardiography
#13
Stephanie L C Scofield, Krishna Singh
Many animal models have been established for the study of myocardial remodeling and heart failure due to its status as the number one cause of mortality worldwide. In humans, a pathologic occlusion forms in a coronary artery and reperfusion of that occluded artery is considered essential to maintain viability of the myocardium at risk. Although essential for myocardial recovery, reperfusion of the ischemic myocardium creates its own tissue injury. The physiologic response and healing of an ischemia/reperfusion injury is different from a chronic occlusion injury...
November 24, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27910999/relationship-between-serum-cytokines-receptors-and-matrix-metalloproteinase-9-levels-and-coronary-artery-disease
#14
Seyed Reza Mirhafez, Amir Avan, Mohammad Tajfard, Shabnam Mohammadi, Mohsen Moohebati, Arash Fallah, Hamed Ghazavi, Hossein Savadi, Majid Ghayour Mobarhan
BACKGROUND: The prevalence of coronary artery disease (CAD) is increasing globally, supporting the need for the identification of novel biomarkers. Therefore in the present study, we have explored the association of SIL2A, SIL6R, STNFRI, STNFRII, and MMP9 in CAD patients. METHODS: Twenty one patients with angiographically defined CAD with more than 50% occlusion, at least, in one coronary artery and twenty healthy subjects (n=20) without the history of cardiovascular symptoms were enrolled...
December 2, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27910804/sudden-cardiac-death-a-nationwide-cohort-study-among-the-young
#15
Bjarke Risgaard
Sudden cardiac death (SCD) is a tragic event affecting millions of individuals worldwide. Although several studies have investigated the epidemiology of SCD, these studies may have been affected by reporting and referral biases, which are reflected in the very different incidence rates and causes of deaths that have previously been reported. Among SCD victims aged < 36 years, inherited cardiac diseases are well known to play an important role. However, the extent to which inherited cardiac diseases also play a role in SCD victims aged < 50 years has not been completely described...
December 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27910301/minimalist-immediate-mechanical-intervention-approach-in-the-management-of-an-acute-proximal-left-anterior-descending-artery-occlusion-with-extensive-thrombus-burden-in-the-left-main-coronary-artery
#16
Laura Cetran, Frédéric Casassus, Guillermo J Tearney, Benjamin Seguy, Pierre Poustis, Pierre Coste, Edouard Gerbaud
No abstract text is available yet for this article.
February 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27910299/native-and-aberrant-left-anterior-descending-artery-arising-from-left-and-right-coronary-sinus-respectively-a-very-rare-congenital-coronary-anomaly
#17
Hiten Patel, Krishna Nemani, Priyank Shah, Arthur Millman, Fayez Shamoon, Meherwan Joshi
No abstract text is available yet for this article.
February 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/27910134/effectiveness-of-handmade-jacky-like-catheter-as-a-single-multipurpose-catheter-in-transradial-coronary-angiography-a-randomized-comparison-with-conventional-two-catheter-strategy
#18
Ismail Erden, Ebru Golcuk, Serdar Bozyel, Emine Cakcak Erden, Yakup Balaban, Kivanc Yalın, Burak Turan
OBJECTIVE: To investigate safety and efficacy of specialized hand-modified "Jacky-Like" catheter (JLC) as a single dual-purpose catheter in transradial coronary angiography. METHODS: Patients over 18 years undergoing diagnostic CAG through right radial artery (RRA) were prospectively enrolled. Procedures were performed with a single JLC modified from a left Judkins (JL) 3.5 catheter or by using 2-catheter approach (2C). Procedures with coronary artery bypass grafts or ventricular angiographies were excluded from the study...
December 2, 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27910111/cystatin-c-and-epicardial-adipose-tissue-as-noninvasive-predictors-of-cardiovascular-risk-in-acromegaly
#19
Anna Aulinas, Iris Crespo, David Viladés, Ruben Leta, Eulàlia Urgell, Betina Biagetti, Susan M Webb, Elena Valassi
BACKGROUND: Acromegaly (ACRO) is associated with elevated cardiovascular risk, although the prevalence of coronary artery disease (CAD) is unclear. Increased epicardial adipose tissue (EAT) and elevated cystatin-C (Cys-C) levels are cardiovascular risk factors, also related to the progression of CAD in several populations. AIMS: To measure the severity and extent of CAD in patients with ACRO and to determine whether either EAT or Cys-C reflect higher cardiovascular risk in patients with ACRO than in healthy controls...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27910082/impact-of-the-presence-of-chronically-occluded-coronary-artery-on-long-term-prognosis-of-patients-with-acute-st-segment-elevation-myocardial-infarction
#20
Maciej Lesiak, Monika Cugowska, Aleksander Araszkiewicz, Marek Grygier, Małgorzata Pyda, Włodzimierz Skorupski, Przemysław Mitkowski, Magdalena Łanocha, Stefan Grajek
BACKGROUND: Multivessel disease (MVD) is a significant risk factor in patients with acute ST-segment elevation myocardial infarction (STEMI). Whether the presence of chronic total occlusion (CTO) poses an additional hazard is still unknown. The objective of this study was to evaluate the impact of CTO on survival in STEMI patients. METHODS: The study group consisted of 836 STEMI patients treated with primary percutaneous coronary intervention (PCI). MVD was diagnosed in 52...
December 2, 2016: Cardiology Journal
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