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Prostate sbrt

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https://www.readbyqxmd.com/read/27890426/patient-reported-quality-of-life-after-stereotactic-body-radiation-therapy-versus-moderate-hypofractionation-for-clinically-localized-prostate-cancer
#1
Skyler Bryce Johnson, Pamela R Soulos, Timothy D Shafman, Constantine A Mantz, Arie P Dosoretz, Rudi Ross, Steven E Finkelstein, Sean P Collins, Simeng Suy, Jeffrey V Brower, Mark A Ritter, Christopher R King, Patrick A Kupelian, Eric M Horwitz, Alan Pollack, Matthew C Abramowitz, Mark A Hallman, Sergio Faria, Cary P Gross, James B Yu
BACKGROUND AND PURPOSE: Evaluate changes in bowel, urinary and sexual patient-reported quality of life following treatment with moderately hypofractionated radiotherapy (<5Gray/fraction) or stereotactic body radiation therapy (SBRT;5-10Gray/fraction) for prostate cancer. MATERIALS AND METHODS: In a pooled multi-institutional analysis of men treated with moderate hypofractionation or SBRT, we compared minimally detectable difference in bowel, urinary and sexual quality of life at 1 and 2years using chi-squared analysis and logistic regression...
November 24, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27881285/conventionally-fractionationed-volumetric-arc-therapy-versus-hypofractionated-stereotactic-body-radiotherapy-quality-of-life-side-effects-and-prostate-specific-antigen-kinetics-in-localized-prostate-cancer
#2
Makbule Tambas, Fulya Agaoglu, Ayca Iribas, Murat Guveli, Yavuz Dizdar, Murat Okutan, Dilek Sahin, Nuri Tenekeci, Emin Darendeliler
OBJECTIVES: To compare conventionally fractionationed volumetric arc therapy (VMAT) and hypofractionated stereotactic body radiotherapy (SBRT) modalities in terms of prostate-specific antigen (PSA) kinetics, toxicity, and quality of life (QOL) in patients with localized prostate cancer. METHODS: Patients received radical radiotherapy as either 33.5 Gy/5 fr for SBRT or 75.6 Gy/35 fr for VMAT. International Prostate Symptom Score (IPSS) and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Prostate Cancer Module (QLQ-PR25) forms were used to assess QOL...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27796820/whole-body-diffusion-weighted-magnetic-resonance-imaging-wb-dw-mri-vs-choline-positron-emission-tomography-computed-tomography-choline-pet-ct-for-selecting-treatments-in-recurrent-prostate-cancer
#3
A J Conde-Moreno, G Herrando-Parreño, R Muelas-Soria, J Ferrer-Rebolleda, R Broseta-Torres, M P Cozar-Santiago, F García-Piñón, C Ferrer-Albiach
OBJECTIVE: To determine the effectiveness of whole-body diffusion-weighted magnetic resonance imaging (WB-DW-MRI) in detecting metastases by comparing the results with those from choline-positron emission tomography-computed tomography (choline-PET/CT) in patients with biochemical relapse after primary treatment, and no metastases in bone scintigraphy, CT and/or pelvic MRI, or metastatic/oligometastatic prostate cancer (PCa). Patients with this disease profile who could benefit from treatment with stereotactic body radiation therapy (SBRT) were selected and their responses to these techniques were rated...
October 31, 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27748126/simple-diagrammatic-method-to-delineate-male-urethra-in-prostate-cancer-radiotherapy-an-mri-based-approach
#4
Tejinder Kataria, Deepak Gupta, Shikha Goyal, Shyam S Bisht, Ravi Chaudhary, Kushal Narang, Susovan Banerjee, Trinanjan Basu, Ashu Abhishek, Sasikumar Sambasivam, Nisha T Vishnu
Stereotactic body radiotherapy (SBRT) is being increasingly utilized in the treatment of prostate cancer. With the advent of high-precision radiosurgery systems, it is possible to obtain dose distributions akin to high-dose rate brachytherapy with SBRT. However, urethral toxicity has a significant impact on the quality of life in patients with prostate cancer. Contouring the male urethra on a CT scan is difficult in the absence of an indwelling catheter. In this pictorial essay, we have used the MRI obtained for radiotherapy planning to aid in the delineation of the male urethra and have attempted to define guidelines for the same...
December 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27709851/comparison-of-dosimetric-performance-among-commercial-quality-assurance-systems-for-verifying-pretreatment-plans-of-stereotactic-body-radiotherapy-using-flattening-filter-free-beams
#5
Jin Beom Chung, Sang Won Kang, Keun Yong Eom, Changhoon Song, Kyoung Sik Choi, Tae Suk Suh
The purpose of this study was to compare the performance of different commercial quality assurance (QA) systems for the pretreatment verification plan of stereotactic body radiotherapy (SBRT) with volumetric arc therapy (VMAT) technique using a flattening-filter-free beam. The verification for 20 pretreatment cancer patients (seven lung, six spine, and seven prostate cancers) were tested using three QA systems (EBT3 film, I'mRT MatriXX array, and MapCHECK). All the SBRT-VMAT plans were optimized in the Eclipse (version 11...
November 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27685123/clinical-experience-with-planning-quality-assurance-and-delivery-of-burst-mode-modulated-arc-therapy
#6
Kristofer Kainz, Douglas Prah, Ergun Ahunbay, X Allen Li
"Burst-mode" modulated arc therapy (hereafter referred to as "mARC") is a form of volumetric-modulated arc therapy characterized by variable gantry rotation speed, static MLCs while the radiation beam is on, and MLC repositioning while the beam is off. We present our clinical experience with the planning techniques and plan quality assurance measurements of mARC delivery. Clinical mARC plans for five representative cases (prostate, low-dose-rate brain, brain with partial-arc vertex fields, pancreas, and liver SBRT) were generated using a Monte Carlo-based treatment planning system...
2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27675906/predictors-of-multidomain-decline-in-health-related-quality-of-life-after-stereotactic-body-radiation-therapy-sbrt-for-prostate-cancer
#7
R T Dess, W C Jackson, S Suy, J Y Lee, Z S Zumsteg, F Y Feng, D A Hamstra, S P Collins, D E Spratt
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675582/effect-of-dose-to-the-bladder-wall-and-trigone-on-late-urinary-flare-following-definitive-stereotactic-body-radiation-therapy-sbrt-for-localized-prostate-cancer
#8
M C Repka, T P Kole, B Wu, M Tong, S Lei, S Suy, A Dritschilo, S P Collins
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675165/dosimetric-validation-of-robotic-prostate-sbrt-with-simultaneous-integrated-dose-escalation-to-dominant-intraprostatic-lesion-using-a-magnetic-resonance-based-3d-printed-prostate-model-in-an-anthropomorphic-pelvis-phantom
#9
H F Xiang, J Cheng, M Alshammari, C Lee, N B Bloch, S Keohan, C Jaffe, J A Efstathiou, A L Zietman, H M Lu, A E Hirsch
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674931/comparative-quality-of-life-outcomes-among-brachytherapy-intensity-modulated-radiation-therapy-imrt-and-stereotactic-body-radiation-therapy-sbrt-for-localized-prostate-cancer-analysis-of-a-multi-institutional-prospective-cohort
#10
J R Broughman, R Basak, G A Dickerson, D S Usinger, K Spearman, R C Chen
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674267/combined-pretreatment-serum-testosterone-concentration-and-risk-stratification-enhances-interpretation-of-prostate-specific-antigen-psa-kinetics-in-localized-prostate-cancer-after-stereotactic-body-radiation-therapy-sbrt
#11
J Wang, D Zhao, D Veruttipong, P A Kupelian, M L Steinberg, C R King
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674262/multicenter-assessment-of-stereotactic-body-radiation-therapy-sbrt-boost-in-intermediate-risk-prostate-cancer-biochemical-failure-and-toxicity
#12
S E Finkelstein, J Forman, E Fernandez, C T Chen, M E Lieberfarb, S Salenius, D E Dosoretz, A Dosoretz, T D Shafman, C A Mantz
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674191/toxicity-and-quality-of-life-report-of-a-phase-2-study-of-stereotactic-body-radiation-therapy-sbrt-for-low-and-intermediate-risk-prostate-cancer
#13
M J Boyer, C Rushing, B Peterson, M A Papagikos, R A Kiteley, W R Lee
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674166/prostate-specific-antigen-kinetics-after-robotic-radiosurgery-based-stereotactic-body-radiation-therapy-sbrt-the-effect-of-pretreatment-clinical-parameters
#14
S R Blacksburg, M R Witten, A E Katz, C Mendez, A Sanchez, V J Martello, N Russo, J A Haas
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674116/prostate-bed-stereotactic-body-radiation-therapy-pb-sbrt-for-postprostatectomy-biochemical-recurrence-first-toxicity-results-of-a-phase-1-dose-escalation-trial
#15
S Sampath, B Yuh, P Frankel, A Liu, P Tsai, P Twardowski, C Stein, M Kawachi, S V Dandapani, T E Schultheiss, J Y C Wong
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27674113/prospective-patient-reported-outcomes-after-stereotactic-body-radiation-therapy-sbrt-for-prostate-cancer-longitudinal-predictors-of-potency-preservation
#16
R T Dess, W C Jackson, D A Hamstra, S Suy, J Y Lee, Z S Zumsteg, H M Sandler, F Y Feng, S P Collins, D E Spratt
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27637137/early-and-multiple-psa-bounces-can-occur-following-high-dose-prostate-stereotactic-body-radiation-therapy-subset-analysis-of-a-phase-1-2-trial
#17
D Nathan Kim, Christopher Straka, L Chinsoo Cho, Yair Lotan, Jingsheng Yan, Brian Kavanagh, David Raben, Susan Cooley, Jeffrey Brindle, Xian Jin Xie, David Pistenmaa, Robert Timmerman
PURPOSE: We hypothesized that high-dose stereotactic body radiation therapy (SBRT) would lead to faster time to nadir and lower nadir values compared with conventional radiation therapy experiences. We now report prostate-specific antigen (PSA) kinetics following high-dose SBRT in patients treated with radiation alone. METHODS AND MATERIALS: Ninety-one patients were enrolled on the phase 1/2 dose escalation study of SBRT for localized prostate cancer. All patients with at least 36 months of follow-up and without hormone therapy were included in this analysis (n = 47)...
June 24, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/27622157/dose-escalated-stereotactic-body-radiation-therapy-for-prostate-cancer-quality-of-life-comparison-of-two-prospective-trials
#18
Harvey C Quon, Hima Bindu Musunuru, Patrick Cheung, Geordi Pang, Alexandre Mamedov, Laura D'Alimonte, Andrea Deabreu, Liying Zhang, Andrew Loblaw
INTRODUCTION: The optimal prostate stereotactic body radiation therapy (SBRT) dose-fractionation scheme is controversial. This study compares long-term quality of life (QOL) from two prospective trials of prostate SBRT to investigate the effect of increasing dose (NCT01578902 and NCT01146340). MATERIAL AND METHODS: Patients with localized prostate cancer received SBRT 35 or 40 Gy delivered in five fractions, once per week. QOL was measured using the Expanded Prostate Cancer Index Composite at baseline and every 6 months...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/27602330/the-comparison-of-stereotactic-body-radiation-therapy-and-intensity-modulated-radiation-therapy-for-prostate-cancer-by-nccn-risk-groups
#19
Anthony Ricco, Genevieve Manahan, Rachelle Lanciano, Alexandra Hanlon, Jun Yang, Stephen Arrigo, John Lamond, Jing Feng, Michael Mooreville, Bruce Garber, Luther Brady
OBJECTIVES: The primary objective of this study is to compare freedom from biochemical failure (FFBF) between stereotactic body radiation therapy (SBRT) and intensity-modulated radiation therapy (IMRT) for patients with organ confined prostate cancer treated between 2007 through 2012 utilizing the 2015 National Comprehensive Cancer Network (NCCN) risk stratification guidelines. A secondary objective is to compare our updated toxicity at last follow-up compared with pretreatment with respect to bowel, bladder, sexual functioning, and need for invasive procedures between the two groups...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/27587270/plan-quality-and-dosimetric-association-of-patient-reported-rectal-and-urinary-toxicities-for-prostate-stereotactic-body-radiotherapy
#20
X Sharon Qi, Jason P Wang, Caitlin L Gomez, Weber Shao, Xiaoqing Xu, Christopher King, Daniel A Low, Michael Steinberg, Patrick Kupelian
BACKGROUND AND PURPOSE: To study the association between dosimetric parameters with patient-reported quality-of-life (QOL) in urinary irritative/incontinency and bowel functions for prostate stereotactic body radiotherapy (SBRT). MATERIAL AND METHODS: The patient-reported QOL was evaluated using the Expanded Prostate Cancer Index Composite (EPIC-26). According to the progression in QOL score over 12months, patients were assigned to one of three subgroups: score decrement, no change, or increment...
August 29, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
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