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https://www.readbyqxmd.com/read/29683877/robotic-assisted-infrarenal-para-aortic-lymphadenectomy-in-gynecological-cancers-technique-and-surgical-outcomes
#1
Minna M Mäenpää, Kari Nieminen, Eija I Tomás, Tiina H Luukkaala, Johanna U Mäenpää
OBJECTIVE: Mini-invasive surgery has essentially replaced open laparotomy in surgery for endometrial and cervical carcinoma. Of the procedures needed for a complete staging, especially para-aortic lymphadenectomy (PALND) is challenging to perform. The present study was undertaken to investigate the technical and surgical outcomes of robotic-assisted PALND for gynecological cancers in the setting of a tertiary university hospital in Finland. METHODS: This was a retrospective chart review of 283 robotic-assisted para-aortic lymphadenectomies using the single-docking transperitoneal technique performed at the Department of Obstetrics and Gynecology of Tampere University Hospital, in 2009-2016...
April 21, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29681402/-clinical-practice-for-morbidly-obese-endometrial-cancer-patients-a-french-multicentric-study
#2
Cécile Loaec, Edouard Vaucel, Eric Darnis, Patrice Lopes, Gabrielle Selmes, Isabelle Jaffre, Jean-Marc Classe
INTRODUCTION: Morbid obesity may lead to difficulties for management of endometrial cancer. The aim of this study was the assessment of management of endometrial cancer for morbidly obese women and the implementation of recommendations. METHODS: this is retrospective study including women with BMI ≥40kg/m2 treated for endometrial cancer between November 2010 and April 2017 in the university hospital in Nantes and the Cancer Center René Gauducheau in Nantes. Patients' demographics, pre-operative intra operative, post-operative data and survival were analyzed...
April 19, 2018: Bulletin du Cancer
https://www.readbyqxmd.com/read/29676694/keyhole-strategy-aiming-at-minimizing-hospital-stay-for-surgical-clipping-of-unruptured-middle-cerebral-artery-aneurysms
#3
Kentaro Mori, Kojiro Wada, Naoki Otani, Arata Tomiyama, Terushige Toyooka, Satoru Takeuchi, Takuji Yamamoto, Yasuaki Nakao, Hajime Arai
OBJECTIVE Aneurysms of the middle cerebral artery (MCA) are still most often treated by clipping through standard craniotomy, but a longer hospital stay is one of the main drawbacks of this treatment. The authors developed a pterional keyhole clipping strategy for unruptured MCA aneurysms with the intention of minimizing hospital stay. In this paper, they report on their experience with this approach and analyze the long-term neurological and radiological outcomes. METHODS A total of 160 relatively small unruptured MCA aneurysms (mean 6...
April 20, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29675718/ultrasound-guided-brain-surgery-echographic-visibility-of-different-pathologies-and-surgical-applications-in-neurosurgical-routine
#4
Domenico Policicchio, Artan Doda, Enrico Sgaramella, Stefano Ticca, Filippo Veneziani Santonio, Riccardo Boccaletti
BACKGROUND: The use of intraoperative ultrasound (iUS) has increased in the last 15 years becoming a standard tool in many neurosurgical centers. Our aim was to assess the utility of routine use of iUS during various types of intracranial surgery. We reviewed our series to assess ultrasound visibility of different pathologies and iUS applications during the course of surgery. MATERIALS AND METHODS: This is a retrospective review of 162 patients who underwent intracranial surgery with assistance of the iUS guidance system (SonoWand)...
April 19, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29672815/minimally-invasive-isolated-tricuspid-valve-redo-surgery-a-safety-and-outcome-analysis
#5
Gloria Färber, Sophie Tkebuchava, Rodolfo Siordia Dawson, Hristo Kirov, Mahmoud Diab, Peter Schlattmann, Torsten Doenst
BACKGROUND:  Isolated tricuspid valve (TV) surgery is considered a high risk-procedure. The optimal surgical approach is controversial. We analyzed our experience with isolated TV redo surgery performed either minimally invasively (redo-MITS) or through sternotomy. METHODS:  We retrospectively analyzed all patients with previous cardiac surgery who underwent redo-MITS ( n  = 26) and compared them to redo-Sternotomy ( n  = 17). A group of primary-MITS ( n  = 61) served as control...
April 19, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29671358/discoidin-domain-receptors-microenvironment-sensors-that-promote-cellular-migration-and-invasion
#6
Yoshifumi Itoh
Extracellular matrix (ECM) provides cells scaffolding for cell migration and microenvironment for various cellular functions. Collagens are major ECM components in tissue and discoidin domain receptors (DDRs) are receptor tyrosine kinases (RTK) that recognise fibrillar collagens. Unlike other RTK, their ligands are solid ECM the that are abundantly present in the pericellular environment in various tissue, and thus its activation and regulations are unique amongst RTK family. It is emerging that DDRs may be the sensors that monitor and detects changes in ECM microenvironment and determines the cellular fates upon tissue injuries...
April 19, 2018: Cell Adhesion & Migration
https://www.readbyqxmd.com/read/29670905/cortical-bone-trajectory-screws-in-posterior-lumbar-interbody-fusion-minimally-invasive-surgery-for-maximal-muscle-sparing-a-prospective-comparative-study-with-the-traditional-open-technique
#7
Nicola Marengo, Marco Ajello, Michele Federico Pecoraro, Giulia Pilloni, Giovanni Vercelli, Fabio Cofano, Francesco Zenga, Alessandro Ducati, Diego Garbossa
Introduction: A prospective comparative study between classical posterior interbody fusion with peduncular screws and the new technique with divergent cortical screws was conducted. Material and Methods: Only patients with monosegmental degenerative disease were recruited into this study. We analyzed a cohort of 40 patients treated from January 2015 to March 2016 divided into 2 groups (20 patients went to traditional open surgery and 20 patients under mini-invasive strategy)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29663383/nanoparticle-based-targeted-cancer-strategies-for-non-invasive-prostate-cancer-intervention
#8
REVIEW
Nicholas H Farina, Areg Zingiryan, Michael A Vrolijk, Scott D Perrapato, Steven Ades, Gary S Stein, Jane B Lian, Christopher C Landry
Prostate cancer is screened by testing circulating levels of the prostate-specific antigen (PSA) biomarker, monitoring changes over time, or a digital rectal exam. Abnormal results often lead to prostate biopsy. Prostate cancer positive patients are stratified into very low-risk, low-risk, intermediate-risk, and high-risk, based on clinical classification parameters, to assess therapy options. However, there remains a gap in our knowledge and a compelling need for improved risk stratification to inform clinical decisions and reduce both over-diagnosis and over-treatment...
April 16, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29662815/the-treatment-of-left-atrial-appendage-aneurysm-by-a-minimally-invasive-approach
#9
Young Woong Kim, Ho Jin Kim, Min Ho Ju, Jae Won Lee
Left atrial appendage (LAA) aneurysm is a rare, pathologic condition that may lead to atrial tachyarrhythmia or thromboembolic events. A 49-year-old man presented with aggravated palpitation and dizziness. He suffered from refractory atrial fibrillation despite a previous history of radiofrequency catheter ablation. Echocardiography revealed a 57-mm LAA aneurysm. Surgical ablation was performed through a right mini-thoracotomy, and the LAA aneurysm was obliterated with a 50-mm AtriClip (Atricure Inc., Westchester, OH, USA)...
April 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29658823/totally-laparoscopic-mini-alpps-using-a-novel-approach-of-laparoscopic-assisted-transmesenteric-portal-vein-embolization
#10
Juan Pekolj, Fernando A Alvarez, David Biagiola, Lucas Villegas, Victoria Ardiles, Eduardo de Santibañes
BACKGROUND: The initial mortality rates of associating liver partition and portal vein occlusion for staged hepatectomy (ALPPS) were high. However, recent data from the International Registry show a continuous reduction of early mortality and major morbidity due to risk adjustment in patient selection and less invasive techniques in stage-1 surgery. During the first ALPPS International Consensus in 2015, we introduced a paradigm inversion of ALPPS, the so-called "Mini-ALPPS." METHODS: We combined a partial liver partition with a novel technique of laparoscopic-assisted percutaneous cannulation of the inferior mesenteric vein for intraoperative transmesenteric portal vein embolization...
April 16, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29658505/-the-possibilities-of-neurostimulation-sympathetic-correction-in-the-treatment-of-amnestic-korsakoff-s-psychosis
#11
A V Fedotovskih, K Yu Retyunskiy, T S Petrenko, V S Kublanov
AIM: To evaluate the efficacy of non-invasive multichannel electrical stimulation (sympathetic correction) in patients with alcohol amnesic (Korsakoff's) psychosis. MATERIAL AND METHODS: Thirty-seven men, aged 33-48 years, with Korsakoff's (amnestic) psychosis were studied. The duration of disease varied from 12 to 24 month. The device of electrical stimulation of neck nerve structures was used for neuroelectrostimulation. Treatment included 15 sessions within 3 weeks...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29651852/current-treatment-options-of-dupuytren%C3%A2-s-disease
#12
J Kníže, J Miletín, A Nejedlý, M Chorvát, K Novotná, P Tichá, A Fibír, A Sukop, A Knížetová
Dupuytren's disease (fibromatosis of the palmar fascia, benign neoplastic fibromatosis, Dupuytren's contracture) is a disease characterized by growth and successive contracture of single parts of the palmar aponeurosis. This condition is known and has been treated for several centuries. In the advanced stages of the disease, it leads to significant limitation of hand function, resulting in reduced quality of life of the patient. Dupuytren's disease (DD) is a life-long disease with a variable course and a heterogeneous clinical presentation...
2018: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/29649118/optical-dna-biosensor-based-on-square-planar-ethyl-piperidine-substituted-nickel-ii-salphen-complex-for-dengue-virus-detection
#13
Eda Yuhana Ariffin, Ling Ling Tan, Nurul Huda Abd Karim, Lee Yook Heng
A sensitive and selective optical DNA biosensor was developed for dengue virus detection based on novel square-planar piperidine side chain-functionalized N , N '-bis-4-(hydroxysalicylidene)-phenylenediamine-nickel(II), which was able to intercalate via nucleobase stacking within DNA and be functionalized as an optical DNA hybridization marker. 3-Aminopropyltriethoxysilane (APTS)-modified porous silica nanospheres (PSiNs), was synthesized with a facile mini-emulsion method to act as a high capacity DNA carrier matrix...
April 12, 2018: Sensors
https://www.readbyqxmd.com/read/29644289/transpedicular-direct-osteosynthesis-of-hangman-s-fracture-from-a-mini-open-exposure-as-a-less-invasive-procedure-a-technical-note
#14
Viktor Zsolt Kovari, Attila Josvai, Andras Csokay
This surgical technical case report presents initial clinical experience and preliminary results with a less invasive surgical solution for selected hangman's fracture. A well-known stabilization technique (i.e. direct transpedicular osteosynthesis) was applied through a minimally invasive small incision transmuscular posterior approach guided by a standard C-arm fluoroscopy. This mini-open approach to C2 vertebra allows similar dissection, visualization of the bony landmarks, visual control of the transpedicular screw path drilling, tapping and screw insertion to the standard posterior cervical spine approach...
December 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29630054/technique-and-patient-selection-criteria-of-right-anterior-mini-thoracotomy-for-minimal-access-aortic-valve-replacement
#15
Reza Tavakoli, Pascal Leprince, Max Gassmann, Peiman Jamshidi, Nassrin Yamani, Julien Amour, Guillaume Lebreton
Aortic valve stenosis has become the most prevalent valvular heart disease in developed countries, and is due to the aging of these populations. The incidence of the pathology increases with growing age after 65 years. Conventional surgical aortic valve replacement through median sternotomy has been the gold standard of patient care for symptomatic aortic valve stenosis. However, as the risk profile of patients worsens, other therapeutic strategies have been introduced in an attempt to maintain the excellent results obtained by the established surgical treatment...
March 26, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29626458/re-expansion-pulmonary-edema-after-asd-closure-through-right-sided-mini-thoracotomy
#16
Keiichi Hirose, Senri Miwa, Hisashi Sakaguchi, Shinya Takimoto, Yukiyo Yoshida, Yohei Onga, Yuichi Tara, Kazuo Yamanaka
We described a case suffering from re-expanded pulmonary edema (RPE) after atrial septal defect (ASD) closure through right-sided mini-thoracotomy. After re-expansion of the right lung after weaning from cardiopulmonary bypass (CPB), a large amount of serous slight-hemorrhagic bronchial secretions spilled out from the right bronchus. Positive pressure ventilation and differential ventilation were used. We found no bleeding and decreased secretions 24 hours after the onset of RPE. She was extubated 42 hours after the operation...
April 4, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29623859/non-invasive-cerebellar-stimulation-in-cerebellar-disorders
#17
Roberta Ferrucci, Ciara Di Nuzzo, Fabiana Ruggiero, Francesca Cortese, Ilaria Cova, Alberto Priori
Non-invasive brain stimulation (NIBS) might be a valuable therapeutic approach for neurological diseases by modifying the cortical activity in the human brain and promoting neural plasticity. Currently, researchers are exploring the use of NIBS on the cerebellum to promote functional neural changes in cerebellar disorders. In the presence of cerebellar dysfunction, several movement disorders, such as kinetic tremor, ataxia of gait, limb dysmetria and oculomotor deficits, become progressively more disabling in daily life, and no pharmacological treatments currently exist...
April 3, 2018: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/29619020/molecular-detection-of-azole-resistant-aspergillus-fumigatus-in-clinical-samples
#18
REVIEW
Jochem B Buil, Jan Zoll, Paul E Verweij, Willem J G Melchers
Aspergillus diseases are often caused by Aspergillus fumigatus . Azoles are the mainstay of therapy, but the management of aspergillosis is hampered by the emergence of azole resistance. Rapid detection of azole resistance might benefit treatment outcome by early treatment modifications. However, the yield of fungal culture in invasive aspergillosis is low and susceptibility testing requires several days to be completed. To overcome the low yield of fungal cultures and slow detection of resistance, it is possible to use molecular tools directly on clinical specimens in order to rapidly detect molecular markers of azole resistance...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29617839/outcomes-of-aortic-valve-replacement-via-partial-upper-sternotomy-versus-conventional-aortic-valve-replacement-in-obese-patients
#19
Henryk A Welp, Isabell Herlemann, Sven Martens, Heinz Deschka
OBJECTIVES: Excellent outcomes after minimally invasive aortic valve replacement (mini-AVR) have been reported. Therefore, mini-AVR has become a popular treatment option in many cardiac surgery centres. However, whether obese patients particularly benefit from mini-AVR remains unclear. The aim of the present study was to evaluate outcomes of AVR performed through partial upper sternotomy compared to AVR through a full sternotomy (full-AVR) in obese patients. METHODS: We retrospectively reviewed the medical records of all patients who underwent isolated AVR at our institution, and 217 consecutive obese [body mass index (BMI) >30 kg/m2] patients were identified...
March 30, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29610733/peculiarities-of-intra-thoracic-colon-interposition-eso-coloplasty-indications-surgical-management-and-outcomes
#20
REVIEW
Lucile Gust, Henri De Lesquen, Ilies Bouabdallah, Geoffrey Brioude, Pascal-Alexandre Thomas, Xavier-Benoit D'journo
Stomach is the usual organ of choice for oesophageal replacement. Gastric pull-up is a standardized, fast and secure procedure, requiring only one anastomosis and usually performed with mini-invasive techniques. Colon is used when the stomach is not available, for tumours of the upper oesophagus or the hypopharynx, for benign or paediatric diseases. It is a complex surgery requiring a specific pre-operative management, three or four anastomoses, and a careful choice of the route of reconstruction. Early post-operative complications, such as anastomotic leakage, are frequent...
February 2018: Annals of Translational Medicine
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