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https://www.readbyqxmd.com/read/29444079/sensitive-and-less-invasive-confirmatory-diagnosis-of-visceral-leishmaniasis-in-sudan-using-loop-mediated-isothermal-amplification-lamp
#1
Maowia Mukhtar, Sababil S Ali, Salah A Boshara, Audrey Albertini, Séverine Monnerat, Paul Bessell, Yasuyoshi Mori, Yutaka Kubota, Joseph M Ndung'u, Israel Cruz
BACKGROUND: Confirmatory diagnosis of visceral leishmaniasis (VL), as well as diagnosis of relapses and test of cure, usually requires examination by microscopy of samples collected by invasive means, such as splenic, bone marrow or lymph node aspirates. This causes discomfort to patients, with risks of bleeding and iatrogenic infections, and requires technical expertise. Molecular tests have great potential for diagnosis of VL using peripheral blood, but require well-equipped facilities and trained personnel...
February 14, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29433583/mid-term-survivorship-of-cruciate-retaining-versus-posterior-stabilized-total-knee-arthroplasty-using-modular-mini-keel-tibial-implants
#2
Cheng-Pang Yang, Kuo-Yao Hsu, Yu-Han Chang, Yi-Sheng Chan, Hsin-Nung Shih, Alvin Chao-Yu Chen
BACKGROUND: Reports of diverse outcomes in modular mini-keel tibial componentry for total knee arthroplasty (TKA) have raised concerns about early aseptic loosening. Cruciate-retaining (CR) prostheses, using mini-keel implants, have yet to be reported and compared to posterior-stabilizing (PS) designs. METHODS: A retrospective, case-matched study of 91 consecutive TKAs (n = 46 CR; n = 45 PS prostheses), using modular mini-keel tibial componentry with a 45-mm drop down stem extension, was conducted...
February 13, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29422252/achieving-high-quality-standards-in-laparoscopic-colon-resection-for-cancer-a-delphi-consensus-based-position-paper
#3
Laura Lorenzon, Alberto Biondi, Thomas Carus, Adam Dziki, Eloy Espin, Nuno Figueiredo, Marcos Gomez Ruiz, Tamas Mersich, Isacco Montroni, Pieter J Tanis, Stefan Rolf Benz, Paolo Pietro Bianchi, Matthias Biebl, Ivo Broeders, Raffaele De Luca, Paolo Delrio, Mathieu D'Hondt, Alois Fürst, Jan Grosek, Jose Flavio Guimaraes Videira, Friedrich Herbst, David Jayne, György Lázár, Danilo Miskovic, Andrea Muratore, Ole Helmer Sjo, Tom Scheinin, Ales Tomazic, Andreas Türler, Cornelius Van de Velde, Steven D Wexner, Christoph Wullstein, Wojciech Zegarski, Domenico D'Ugo
AIM: To investigate the rate of laparoscopic colectomies for colon cancer using registries and population-based studies. To provide a position paper on mini-invasive (MIS) colon cancer surgery based on the opinion of experts leader in this field. METHODS: A systematic review of the literature was conducted using PRISMA guidelines for the rate of laparoscopy in colon cancer. Moreover, Delphi methodology was used to reach consensus among 35 international experts in four study rounds...
February 5, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29415382/one-year-outcomes-after-rapid-deployment-aortic-valve-replacement
#4
Christopher Young, Günther Laufer, Alfred Kocher, Marco Solinas, Francesco Alamanni, Gianluca Polvani, Bruno K Podesser, Jose Ignacio Aramendi, Jose Arribas, Olivier Bouchot, Ugolino Livi, Massimo Massetti, Kim Terp, Christophe Giot, Mattia Glauber
OBJECTIVE: The goals of rapid-deployment aortic valve replacement include facilitation of minimally invasive surgery and reduced aortic crossclamp time. We report the short-term outcomes of a series of 493 patients undergoing rapid-deployment aortic valve replacement with the EDWARDS INTUITY valve system (Edwards Lifesciences, LLC, Irvine, Calif). METHODS: Assessing Standard oF Care and Clinical Outcomes UsiNg the EDWARDS INTUITY VAlve SysTem in a European multI-center, Active, pOst-market surveillaNce Study was a prospective, multicenter (n = 26) European registry designed to evaluate the safety and performance of the valve system...
February 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29409244/is-achillon-repair-safe-and-reliable-in-delayed-presentation-achilles-tendon-rupture-a-five-year-follow-up
#5
M Yasser Anathallee, Ben Liu, Adam Budgen, James Stanley
BACKGROUND: To assess the outcome of delayed repair of ruptured Achilles tendon using the Achillon mini-open technique. METHODS: A review of all patients who underwent delayed repair (>10 days post injury) of ruptured Achilles tendon with mini invasive technique was compared to acute repairs carried out at the same unit. Leppilahti Score and Achilles Tendon Total Rupture Score (ATRS) were utilised. Complication rates including re-rupture were also reviewed. RESULTS: 14 patients were identified as having delayed repair (11-31 days)...
March 23, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29405770/liquid-biopsy-and-its-role-in-an-advanced-clinical-trial-for-lung-cancer
#6
Donald J Johann, Mathew Steliga, Ik J Shin, Donghoon Yoon, Konstantinos Arnaoutakis, Laura Hutchins, Meeiyueh Liu, Jason Liem, Karl Walker, Andy Pereira, Mary Yang, Susanne K Jeffus, Erich Peterson, Joshua Xu
Liquid biopsy methodologies, for the purpose of plasma genotyping of cell-free DNA (cfDNA) of solid tumors, are a new class of novel molecular assays. Such assays are rapidly entering the clinical sphere of research-based monitoring in translational oncology, especially for thoracic malignancies. Potential applications for these blood-based cfDNA assays include: (i) initial diagnosis, (ii) response to therapy and follow-up, (iii) tumor evolution, and (iv) minimal residual disease evaluation. Precision medicine will benefit from cutting-edge molecular diagnostics, especially regarding treatment decisions in the adjuvant setting, where avoiding over-treatment and unnecessary toxicity are paramount...
February 2018: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29398585/does-intraoperative-success-predict-outcome-in-the-treatment-of-urethral-sphincter-insufficiency-with-bulking-agent
#7
Niklas Pakkasjärvi, Seppo Taskinen
INTRODUCTION: Sphincter insufficiency is mostly associated with neurogenic and some structural abnormalities in the pediatric population. As a mini-invasive treatment, urethral bulking agents have been used to treat this problem. OBJECTIVE: The aim was to evaluate if technical success, defined as intraoperative increase in abdominal leak point pressure (ALPP), predicts the outcome of the treatment of sphincter insufficiency with urethral bulking agent. STUDY DESIGN: We reviewed all children treated first time with dextranomer/hyaluronic acid (Dx/HA) copolymer (Deflux) for urethral sphincter insufficiency and who intraoperatively had ALPPs measured during 2004-2014...
January 31, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29395723/short-stems-versus-conventional-stems-in-cementless-total-hip-arthroplasty-a-long-term-registry-study
#8
Federico Giardina, Francesco Castagnini, Susanna Stea, Barbara Bordini, Maurizio Montalti, Aldo Toni
BACKGROUND: Short stems in total hip arthroplasty (THA) have recently gained increasing popularity, allowing mini-invasive exposures and bone-sparing approaches. However, long-term studies and recommendations for the routine use are not available. The aim of this report was to compare the survival rates and the reasons for revision of short stems versus conventional stems in cementless THAs, in a registry-based population. METHODS: The Registry of Prosthetic Orthopedic Implants (RIPO) was inquired about cementless THAs performed since 2000 to 2016...
January 11, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29380691/advances-in-nanostructure-mediated-hyperthermia-in-tumor-therapies
#9
Jian-Ping Dou, Qun-Fang Zhou, Ping Liang, Jie Yu
Hyperthermia has been proposed as a promising treatment modality for its advantageous profiles such as mini/non-invasiveness, good tolerability, and cost-effectiveness. Quick development of nanotechnology in recent years has greatly broadened the application area of hyperthermia and endowed it with attractive new functions. Thermal sensitive nanostructures can absorb energy from an external source. They can control the therapeutic heating only in the targeted region without damage to normal tissues. They can also be loaded with therapeutic drugs and/or functionalized with imaging properties to construct multifunctional theranostic nanoplatforms...
January 29, 2018: Current Drug Metabolism
https://www.readbyqxmd.com/read/29373311/-how-i-do%C3%A2-sacrospinofixation-following-richter-technique-by-mini-invasive-vaginal-route
#10
F Margueritte, C Sallée, Y Aubard, T Gauthier
No abstract text is available yet for this article.
January 16, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29372857/early-experience-of-placing-image-guided-minimally-invasive-pedicle-screws-without-k-wires-or-bone-anchored-trackers
#11
Gregory M Malham, Rhiannon M Parker
OBJECTIVE Image guidance for spine surgery has been reported to improve the accuracy of pedicle screw placement and reduce revision rates and radiation exposure. Current navigation and robot-assisted techniques for percutaneous screws rely on bone-anchored trackers and Kirchner wires (K-wires). There is a paucity of published data regarding the placement of image-guided percutaneous screws without K-wires. A new skin-adhesive stereotactic patient tracker (SpineMask) eliminates both an invasive bone-anchored tracker and K-wires for pedicle screw placement...
January 26, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29367093/a-mini-fluid-challenge-of-150ml-predicts-fluid-responsiveness-using-modelflowr-pulse-contour-cardiac-output-directly-after-cardiac-surgery
#12
Annemieke Smorenberg, Thomas G V Cherpanath, Bart F Geerts, Robert B P de Wilde, Jos R C Jansen, Jacinta J Maas, A B Johan Groeneveld
STUDY OBJECTIVE: The mini-fluid challenge may predict fluid responsiveness with minimum risk of fluid overloading. However, the amount of fluid as well as the best manner to evaluate the effect is unclear. In this prospective observational pilot study, the value of changes in pulse contour cardiac output (CO) measurements during mini-fluid challenges is investigated. DESIGN: Prospective observational study. SETTING: Intensive Care Unit of a university hospital...
January 19, 2018: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29366476/salmonella-typhimurium-metabolism-affects-virulence-in-the-host-a-mini-review
#13
REVIEW
Ana Herrero-Fresno, John Elmerdhahl Olsen
Salmonella enterica remains an important food borne pathogen in all regions of the world with S. Typhimurium as one of the most frequent serovars causing food borne disease. Since the majority of human cases are caused by food of animal origin, there has been a high interest in understanding how S. Typhimurium interacts with the animal host, mostly focusing on factors that allow it to breach host barriers and to manipulate host cells to the benefit of itself. Up to recently, such studies have ignored the metabolic factors that allow the bacteria to multiply in the host, but this is changing rapidly, and we are now beginning to understand that virulence and metabolism in the host are closely linked...
May 2018: Food Microbiology
https://www.readbyqxmd.com/read/29360997/novel-regenerative-therapy-combined-with-transphrenic-peritoneoscopy-assisted-omentopexy
#14
Satoshi Kainuma, Kiyokazu Nakajima, Shigeru Miyagawa, Satsuki Fukushima, Atsuhiro Saito, Akima Harada, Masashi Hirota, Yasuhiro Miyazaki, Noriyoshi Sawabata, Tadashi Watabe, Hiroshi Watabe, Koichi Toda, Jun Hatazawa, Meinoshin Okumura, Yoshiki Sawa
OBJECTIVES: We previously reported that cell sheet transplantation combined with an omentopexy (OP) procedure is more effective for repairing heart damage when compared with cell sheet transplantation alone. However, a simultaneous (conventional) laparotomy as part of the OP may adversely affect the general condition of critically ill heart failure patients who would otherwise benefit from cell sheet transplantation, which is a paradox to be reconciled before this treatment can be applied in a clinical setting...
January 18, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29356942/mid-term-outcome-of-arthroscopic-amic-for-the-treatment-of-articular-cartilage-defects-in-the-knee-joint-is-equivalent-to-mini-open-procedures
#15
J Schagemann, P Behrens, A Paech, H Riepenhof, B Kienast, H Mittelstädt, J Gille
INTRODUCTION: We present the first retrospective study that compares two various autologous matrix-induced chondrogenesis (AMIC) surgical interventions to repair grade III-IV cartilage defects in the knee. Patients who underwent minimally invasive (arthroscopy) or open (mini-arthrotomy) AMIC were followed up to 2 years to investigate if minimally invasive AMIC is superior to open procedures. MATERIALS AND METHODS: Overall n = 50 patients with focal and contained grade III-IV articular cartilage defects in the knee joint were followed in a consecutive cohort study...
January 22, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29353871/minimally-invasive-cardiac-surgery-in-china-multi-center-experience
#16
Kun Hua, Yang Zhao, Ran Dong, Taoshuai Liu
BACKGROUND To the best of our knowledge, there is no nationwide data available on the development of minimally invasive cardiac surgery (MICS) in China. The purpose of this study was to report the results of MICS in 6 experienced centers in China. MATERIAL AND METHODS From September 2014 to July 2016, 1241 patients with cardiac conditions who underwent MICS procedures were randomly enrolled in 6 centers in China, and those patients were randomly selected for inclusion in this study. The MICS procedures were defined as any cardiac surgery performed through a less invasive incision, rather than a complete median sternotomy, mainly including mini-incision surgery (400, 32...
January 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29353464/laparoscopic-2port-varicocelectomy-with-scarless-periumblical-mini-incision-initial-experience-in-approach-and-outcomes
#17
Won Ik Seo, Jong Kyou Kwon, Pil Moon Kang, Wansuk Kim, Jang Ho Yoon, Taek Sang Kim, Jae Seung Chung, Cheol Kyu Oh
PURPOSE: As with other areas, there have been many efforts for minimally invasive surgery in varicocelectomy. We present our initial experience with laparoscopic varicocelectomy with a two-port scarless periumbilical mini-incision. MATERIALS AND METHODS: The study enrolled 18 patients who underwent laparoscopic varicocelectomy with a twoportscarless periumbilical mini-incision from February 2012 to April 2013. The laparoscopic varicocelectomy was performed using two 5-mm ports at periumbilical sites in skin creases...
January 21, 2018: Urology Journal
https://www.readbyqxmd.com/read/29349999/-percutaneous-endoscopic-lumbar-discectomy-combined-with-epidural-injection-for-prolapsed-lumbar-disc-herniation
#18
Hai-Hao Wu, Tao Tang, Qing-Jiang Pang, Yun Wang, Zong-Kai Zhang
OBJECTIVE: To assess the effect of percutaneous endoscopic lumbar discectomy (PELD) combined with epidural injection for prolapsed lumbar disc herniation(PLDH). METHODS: In this prospective randomized controlled study, the clinical data of 126 patients who had undergone a PELD because of a single-level PLDH from March 2014 to June 2015 were analyzed. There were 67 males and 59 females, ranging in age from 17 to 75 years old with an average of(41.0±13.5) years old, 9 cases were L₃,₄, 76 cases were L₄,₅ and 41 cases were L₅S₁...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29342018/mini-or-less-open-sublay-operation-milos-a-new-minimally-invasive-technique-for-the-extraperitoneal-mesh-repair-of-incisional-hernias
#19
Wolfgang Reinpold, Michael Schröder, Cigdem Berger, Jennifer Nehls, Alexander Schröder, Martin Hukauf, Ferdinand Köckerling, Reinhard Bittner
OBJECTIVE: Improvement of ventral hernia repair. BACKGROUND: Despite the use of mesh and other recent improvements, the currently popular techniques of ventral hernia repair have specific disadvantages and risks. METHODS: We developed the endoscopically assisted mini- or less-open sublay (MILOS) concept. The operation is performed transhernially via a small incision with light-holding laparoscopic instruments either under direct, or endoscopic visualization...
January 16, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29324792/critical-evaluation-of-colon-submucosal-microdialysis-in-awake-mobile-rats
#20
Norbert Cibicek, Jiri Ehrmann, Jitka Proskova, Rostislav Vecera
Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking. Microdialysis is a mini-invasive technique that may be utilized to continuously deliver or recover low-molecular substances from various tissues. In this experiment we evaluated the feasibility of in vivo microdialysis to monitor extracellular fluid chemistry in the descending colon submucosa of conscious, freely moving rodents. Following surgical implantation of a microdialysis probe, male Wistar rats were housed in metabolic cages where they were analgized and clinically followed for four days with free access to standard diet and water...
2018: PloS One
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