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phaeohyphomycosis

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https://www.readbyqxmd.com/read/28764590/vasculitis-causing-massive-infarction-a-rare-presentation-of-primary-cerebral-phaeohyphomycosis
#1
Rajalakshmi Poyuran, B H Srinivas, Bhawana A Badhe
No abstract text is available yet for this article.
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/28761846/phaeohyphomycosis-of-the-face-masquerading-as-basal-cell-carcinoma-in-an-immunocompetent-patient
#2
Sharma Shruti, Avninder Singh, V Ramesh, Fouzia Siraj
Pheohyphomycosis is a rare heterogeneous group of mycotic infections caused by dermatiaceous (phaeoid) fungi affecting the skin, subcutaneous tissue, and the central nervous system.Involvement of the face is extremely rare, and very few cases have been reported in India so far. We reporta case of phaeohyphomycosisin a 45-year-old female with 1-year history of a well- defined hypertrophic plaque over the right cheek advancing towards the forehead. The lesion was ulcerated with rolled-up margins; a provisional clinical diagnosis of basal cell carcinoma was given...
July 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28670680/subcutaneous-mycoses-in-peru-a-systematic-review-and-meta-analysis-for-the-burden-of-disease
#3
Max Carlos Ramírez Soto, German Malaga
BACKGROUND: There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES: This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which fungal species were commonly associated with these mycoses. METHODS: We performed a meta-analysis after a systematic review of the published literature in PubMed, LILACS, and SciELO to estimate the burden of subcutaneous mycoses in 25 regions in Peru...
July 3, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28631431/phaeohyphomycosis-breast-masquerading-as-fibroadenoma-in-a-young-teenage-girl
#4
Amita Jain Gupta, Meeta Singh, Surekha Yadav, Nita Khurana, Shyam Lata Jain, Rohit Chawla, Sunil Laka, Anurag Mishra
Phaeohyphomycosis is an unusual granulomatous fungal infection, observed in immunocompromised or diabetic patients; however, it is even rarer in immunocompetent patients. Cytological findings of the same have been infrequently reported. The histopathological diagnosis or fungal culture helps in definitive diagnosis to identify the exact fungal species. Hereby, we report a rare case of invasive fungal infection in a breast lump in a young female, presenting as fibroadenoma breast. Fine needle aspiration cytology from the breast lesion showed the presence of septate acute-angled branching fungal hyphae with focal pigmentation, morphologically suggestive of phaeohyphomycosis which was positive with fungal stains...
June 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28627488/diversity-of-veronaea-botryosa-from-different-hosts-and-evaluation-of-laboratory-challenge-models-for-phaeohyphomycosis-in-acipenser-transmontanus
#5
Esteban Soto, Christine Richey, Stephen R Reichley, Brittany Stevens, Kirsten V Kenelty, Janiee Lewis, Barbara Byrne, Nathan P Wiederhold, Thomas B Waltzek, Matthew F Sheley, Alvin C Camus, Matt J Griffin
Veronaea botryosa has been identified as a pathogen of cultured white sturgeon Acipenser transmontanus. In 2015, samples from 19 white sturgeon were received for diagnosis, of which 14 cultured positive for V. botryosa. Intraspecific variability among V. botryosa isolates from different clinically affected hosts and geographic regions was investigated using repetitive extragenic palindromic PCR fingerprinting (rep-PCR). The rep-PCR profiles of 16 V. botryosa isolates from a human, sea turtles, and cultured fish were distinct from those of other phaeoid fungi belonging to the genera Cladophialophora and Exophiala...
June 19, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/28578629/chaetomiaceae-fungi-novel-pathogens-of-equine-neurotropic-phaeohyphomycosis
#6
Quinci Plumlee, Courtney Meason-Smith, Alexandra Dieterly, Gabriel Gomez, Brian F Porter, Aline Rodrigues Hoffmann
Many previously unrecognized fungi are emerging as potential pathogens. One such group is dematiaceous fungi of the Chaetomiaceae family (phylum Ascomycota, class Sordariomycetes). These fungi are rare causes of opportunistic, neurotropic phaeohyphomycosis in humans but are not known to cause similar infections in animals. The aims of this study were to investigate equine hyphal mycotic encephalitis, characterize key histopathologic features, and classify causative organisms with molecular diagnostic techniques...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28566662/practical-management-of-deep-cutaneous-fungal-infections
#7
Tomotaka Sato
Understanding deep cutaneous fungal infection requires not only reading many case reports and checking the typical clinical images of skin lesions, but also managing the patients properly to prevent misdiagnosis. Herein, I review my recent experiences with eight typical cases of deep cutaneous infections (including protothecosis and nocardiosis) in Japan. It is very important to do the four management processes; namely, KOH direct microscopic examination, skin biopsy, fungal culture, and microscopic examination of the histopathological specimen of PAS and Grocott staining...
2017: Medical Mycology Journal
https://www.readbyqxmd.com/read/28558644/a-case-of-subcutaneous-phaeohyphomycosis-associated-with-leprosy
#8
Márcia M R Teixeira, Claudia B Assunção, Renata R Gomes, Fabiana Rocha-Silva, Sônia M de Figueiredo, Elen R R Teixeira, Adriana S Carneiro, Rogério J M B Júnior, Vânia Vicente, Rachel Basques Caligiorne
Subcutaneous phaeohyphomycosis is a form of infection caused by dematiaceous fungi and frequently reported in the literature. It is considered as an emerging mycosis because it is increasingly reported among immunosuppressive patients. The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria spp. We present a case of a 48-year-old woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive doses due to a type 2 repetitive reaction leprosy outbreak, revealing subcutaneous phaeohyphomycosis lesions...
May 30, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28500778/phaeohyphomycosis-due-to-exophiala-infections-in-solid-organ-transplant-recipients-case-report-and-literature-review
#9
Kate E Oberlin, Anna J Nichols, Rossana Rosa, Adriana Dejman, Adela Mattiazzi, Giselle Guerra, George W Elgart, Lilian M Abbo
This case report and literature review underscores the cutaneous presentations of phaeohyphomycosis in the solid organ transplant population. Increased cognizance with prompt identification is critical. The therapy and clinical outcomes of phaeohyphomycosis, caused by the Exophiala genus, in the solid organ transplant population, is analyzed to examine optimal care. This review highlights the inherent difficulties in providing the appropriate duration of antifungal therapy to avoid relapsing infections in immunosuppressed patients...
August 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28491444/cerebral-pyogranulomatous-encephalitis-caused-by-cladophialophora-bantiana-in-a-15-week-old-domestic-shorthair-kitten
#10
Elise B Russell, Marcus N Gunew, Michelle M Dennis, Catriona L Halliday
CASE SUMMARY: A case of cerebral phaeohyphomycosis caused by Cladophialophora bantiana is described in a 15-week-old domestic shorthair kitten. RELEVANCE AND NOVEL INFORMATION: Cerebral phaeohyphomycosis is a rare condition in cats caused by dematiaceous fungi. This report describes the clinical and histopathological findings in the youngest case documented in a feline, provides a brief review of aetiology, diagnosis, treatment and prognosis of cerebral phaeohyphomycosis and demonstrates the importance of molecular diagnostics in accurate mycotic species identification...
July 2016: JFMS open reports
https://www.readbyqxmd.com/read/28478966/a-rare-case-of-multiple-brain-abscess-and-probably-disseminated-phaeohyphomycosis-due-to-cladophialophora-bantiana-in-an-immunosuppressed-individual-from-india
#11
S Lahiri Mukhopadhyay, A Mahadevan, V H Bahubali, R Dawn Bharath, A R Prabhuraj, S Maji, N Siddaiah
Cladophialophora bantiana, a dematiaceous neurotropic mold causes rare and lethal brain abscess, commonly in immunocompetent hosts. We report a rare and probably a case of disseminated infection with this black mold in an immunosuppressed individual from India. A 55-year-old diabetic male presented with severe headache, blurred-vision, behavioural abnormalities, eye-pain and ear-discharge. He was undergoing treatment for hypertension, prostatomegaly and obstructive pulmonary disease. He was on steroids for the past six years for uveitis...
May 3, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28447292/ecology-of-the-human-opportunistic-black-yeast-exophiala-dermatitidis-indicates-preference-for-human-made-habitats
#12
Monika Novak Babič, Jerneja Zupančič, Nina Gunde-Cimerman, Sybren de Hoog, Polona Zalar
Exophiala dermatitidis is an ascomycetous black yeast from the order Chaetothyriales. Its growth characteristics include the polymorphic life cycle, ability to grow at high and low temperatures, at a wide pH range, survival at high concentrations of NaCl, and survival at high UV and radioactive radiation. Exophiala dermatitidis causes deep or localized phaeohyphomycosis in immuno-compromised people worldwide and is regularly encountered in the lungs of cystic fibrosis patients. Regardless of numerous ecological studies worldwide, little is known about its natural habitat or the possible infection routes...
April 26, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28365816/multiple-brain-abscesses-caused-by-rhinocladiella-mackenziei-in-an-immunocompetent-patient-a-case-report-and-literature-review
#13
Natan Yusupov, Ashirwad Merve, Clare E Warrell, Elizabeth Johnson, Carmel Curtis, George Samandouras
Primary cerebral phaeohyphomycosis due to Rhinocladiella mackenziei is an extremely rare infection carrying more than 80% mortality, with most cases reported from the Middle East region. This darkly pigmented black yeast is highly neurotropic, aggressive and refractory to most antifungal agents. Here we present an immunocompetent elderly male, presenting with multiple brain abscesses, with R. mackenziei confirmed by nuclear ribosomal repeat region sequencing, who was successfully treated by surgical debridement and intravenous voriconazole...
April 1, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28349548/multifocal-but-non-disseminated-phaeohyphomycosis-in-a-healthy-man-via-a-unique-mechanism-ejection-from-mva-into-a-vegetable-field-in-afghanistan-resulting-in-multiple-contaminated-skin-wounds
#14
M Omer Malakzai, Janat Gul Sahak, Ryan Campbell, Mirwais Abobakar, Daniel R Hoogestraat, Dhruba J SenGupta, Andrew Bryan, Jerad M Gardner
A 20 year-old male presented with multiple subcutaneous nodules on the head, neck, chest and oral cavity. FNA and biopsy showed pigmented fungal hyphae diagnostic of multifocal phaeohyphomycosis, found to be Exophiala spinifera by molecular diagnostics. The presentation initially raised concern for disseminated disease and occult immunosuppression. However, the patient appeared to be immunocompetent and otherwise healthy. Upon further inquiry, the patient was in a motor vehicle accident four years before presentation; he was ejected into a vegetable field resulting in multiple open wounds...
March 28, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28348770/non-traumatic-keratitis-due-to-colletotrichum-truncatum
#15
Reina Llamos, Abdullah M S Al-Hatmi, Gerardo Martínez, Ferry Hagen, Rosario Velar, Alexeide de la Caridad Castillo Pérez, Jacques F Meis, María T Illnait-Zaragozí
INTRODUCTION: The fungal genus Colletotrichum is an uncommon cause of human infections. It has been implicated in cutaneous phaeohyphomycosis, artritis and keratitis secondary to traumatic implantation. CASE PRESENTATION: We report two cases of keratitis due Colletotrichum truncatum in middle-aged, immunocompetent persons without history of trauma. The aetiological agents were identified based on DNA sequencing. Azoles and echinocandins showed high minimal inhibitory concentrations while amphotericin B was ≤ 0...
August 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28348446/exploring-the-genomic-diversity-of-black-yeasts-and-relatives-chaetothyriales-ascomycota
#16
M M Teixeira, L F Moreno, B J Stielow, A Muszewska, M Hainaut, L Gonzaga, A Abouelleil, J S L Patané, M Priest, R Souza, S Young, K S Ferreira, Q Zeng, M M L da Cunha, A Gladki, B Barker, V A Vicente, E M de Souza, S Almeida, B Henrissat, A T R Vasconcelos, S Deng, H Voglmayr, T A A Moussa, A Gorbushina, M S S Felipe, C A Cuomo, G Sybren de Hoog
The order Chaetothyriales (Pezizomycotina, Ascomycetes) harbours obligatorily melanised fungi and includes numerous etiologic agents of chromoblastomycosis, phaeohyphomycosis and other diseases of vertebrate hosts. Diseases range from mild cutaneous to fatal cerebral or disseminated infections and affect humans and cold-blooded animals globally. In addition, Chaetothyriales comprise species with aquatic, rock-inhabiting, ant-associated, and mycoparasitic life-styles, as well as species that tolerate toxic compounds, suggesting a high degree of versatile extremotolerance...
March 2017: Studies in Mycology
https://www.readbyqxmd.com/read/28295973/cutaneous-phaeohyphomycosis-in-a-hematopoietic-stem-cell-transplant-patient-caused-by-alternaria-rosae-first-case-report
#17
Amy W Liu, Allen C Bateman, Adam Greenbaum, Kanishka Garvin, Jill Clarridge, Jonathan Grim
Alternaria species have been reported as a rare cause of fungal infection in organ and stem cell transplant recipients, but to date, no reports have been published of infection in humans caused by Alternaria rosae. Here, we report cutaneous A. rosae infection in a 66-year-old farmer with a history of primary myelofibrosis who had undergone allogeneic unrelated donor hematopoietic stem cell transplantation. Forty-nine days post transplant, he presented with a nodule on the thumb with no findings suggestive of disseminated infection...
June 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/28295266/cutaneous-phaeohyphomycosis
#18
Mariana P Caviedes, Ana C Torre, Maite Lisa Eliceche, Denise C Valdivia Monteros, Victoria I Volonteri, Ricardo L Galimberti
BACKGROUND: Phaeohyphomycosis is an infrequent infection in human beings. However, in recent years, its prevalence has augmented in immunosuppressed patients (mostly in solid organ transplanted patients). Infection can be mucocutaneous or disseminated. In the former, the fungus inoculation occurs mainly through traumatism. Lesions may be polymorphic and asymptomatic, isolated or multiple, and are usually localized in exposed areas of the limbs and head. Treatment is not standardized. When possible, surgical resection of the lesion is combined with systemic antifungals...
April 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28293689/fungal-melanonychia-ungual-phaeohyphomycosis-caused-by-botryosphaeria-dothidea
#19
Hiromitsu Noguchi, Masataro Hiruma, Tadahiko Matsumoto, Rui Kano, Masaru Tanaka, Takashi Yaguchi, Kazuhiro Sonoda, Hironobu Ihn
No abstract text is available yet for this article.
June 9, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/28275534/disseminated-phaeohyphomycosis-in-a-dog
#20
Lana S Rothenburg, Timothy A Snider, Allison Wilson, Anthony W Confer, Akhilesh Ramachandran, Rinosh Mani, Theresa Rizzi, Laura Nafe
Phaeohyphomycosis is a rare but emerging disease caused by dematiaceous fungi. Here we describe the case of an immunosuppressed dog with disseminated phaeohyphomycosis secondary to Bipolaris spicifera infection. Regionally extensive infiltration of the paw pads, skin, myocardium, liver, renal interstitium and diaphragm was identified on histopathology. Candida glabrata and Fusarium oxysporum were also cultured from multiple sites post-mortem. The dog was treated with fluconazole, itraconazole, terbinafine and liposomal amphotericin B, but was euthanized due to its poor prognosis after 12 days of therapy...
March 2017: Medical Mycology Case Reports
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