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phaeohyphomycosis

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https://www.readbyqxmd.com/read/27904058/two-cases-of-chromomycosis-identified-by-molecular-phylogenetic-analysis
#1
Takayo Mitomo, Yukiko Ushigome, Tomoo Fukuda, Yoko Kano, Tetsuo Shiohara
Chromomycosis is an infection caused by dematiaceous fungi. These fungi belong to several genera with varied clinical presentations and parasitic forms. The disease is roughly classified into three types: chromoblastomycosis, black-grain mycetoma, and phaeohyphomycosis. While there are many kinds of dematiaceous fungi, the major etiologic agent is Fonsecaea pedrosoi, which to date has accounted for 90% of chromoblastomycosis cases. The genus Fonsecaea has recently been assessed via rRNA ITS sequence analysis, and species have been classified into F...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27866319/successful-posaconazole-therapy-of-disseminated-alternariosis-due-to-alternaria-infectoria-in-a-heart-transplant-recipient
#2
Pavlina Lyskova, Milos Kubanek, Vit Hubka, Eva Sticova, Ludek Voska, Dana Kautznerova, Miroslav Kolarik, Petr Hamal, Martina Vasakova
We report a case of phaeohyphomycosis caused by Alternaria infectoria in a 61-year-old heart transplant recipient with multiple skin lesions and pulmonary infiltrates. The infection spread via the haematogenous route from the primary cutaneous lesions into the lungs. The diagnosis was based on the histopathological examination, direct microscopy, skin lesion cultures and detection of Alternaria DNA in the bronchoalveolar lavage fluid using molecular methods. The treatment consisted of a combination of surgical excision and systemic antifungal therapy...
November 19, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27833296/three-rare-cases-of-cutaneous-phaeohyphomycosis
#3
Aditi Chhonkar, Deepti Kataria, Swagata Tambe, Chitra S Nayak
Phaeohyphomycosis is a chronic infectious condition caused by dematiaceous fungi which usually involve the skin and subcutaneous tissue. Subcutaneous phaeohyphomycosis is characterised by papulonodules, verrucous, hyperkeratotic or ulcerated plaques, cysts, abscesses, pyogranuloma, non-healing ulcers or sinuses. In India, commonly associated genera are Exophiala, Phialophora, Cladosporium, Curvularia, Fonsecaea and Alternaria. This condition involves the presence of brown-walled hyphal structures in the dermis and epidermis...
May 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/27822460/the-transcriptome-of-exophiala-dermatitidis-during-ex-vivo-skin-model-infection
#4
Caroline Poyntner, Barbara Blasi, Elsa Arcalis, Ursula Mirastschijski, Katja Sterflinger, Hakim Tafer
The black yeast Exophiala dermatitidis is a widespread polyextremophile and human pathogen, that is found in extreme natural habitats and man-made environments such as dishwashers. It can cause various diseases ranging from phaeohyphomycosis and systemic infections, with fatality rates reaching 40%. While the number of cases in immunocompromised patients are increasing, knowledge of the infections, virulence factors and host response is still scarce. In this study, for the first time, an artificial infection of an ex-vivo skin model with Exophiala dermatitidis was monitored microscopically and transcriptomically...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27735161/subcutaneous-phaeohyphomycosis-caused-by-cladophialophora-bantiana-after-abdominal-hernia-surgery
#5
Vipul M Patel, Bhavin Kapadiya, Viral Shah
Phaeohyphomycosis is a term used to describe infections caused by dematiaceous fungi, i.e. fungi which contain melanin in their cell wall. Cladophialophora bantiana has been implicated to cause brain abscess in immunocompromised patients. Infection caused by Cladophialophora bantiana in an immunocompetent host is relatively rare. Surgical site infection at abdominal subcutaneous tissue caused by Cladophialophora bantiana was noted in this case, which was rarely reported.
May 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27726899/first-case-of-chromoblastomycosis-due-to-phoma-insulana
#6
Francisca Hernández-Hernández, Jaime Vargas-Arzola, Oliver Pedro Ríos-Cruz, Erika Córdova-Martínez, Patricia Manzano-Gayosso, Aristeo Segura-Salvador
Chromoblastomycosis is a chronic infection, caused by pigmented fungi affecting skin and subcutaneous tissues characterized by verrucous nodules or plaques. Fonsecaea pedrosoi and Cladophialophora carrionii are the prevalent agents in the endemic areas. Phoma is an uncommon agent of human infection and involved mainly with phaeohyphomycosis cases. The case of a patient with a history of laceration in foot followed by verrucous aspect and scaly lesions, which had evolved for 27 years is presented. On physical examination disease was clinically compatible with chromoblastomycosis and the microscopic examination of scales showed fumagoid cells...
October 7, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27721785/corneal-phaeohyphomycosis-caused-by-bipolaris-hawaiiensis
#7
Winai Chaidaroon, Sumet Supalaset, Napaporn Tananuvat, Nongnuch Vanittanakom
PURPOSE: To report a rare case of keratitis infected by Bipolaris hawaiiensis. METHODS: A patient who was diagnosed as fungal keratitis caused by B. hawaiiensis was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. RESULTS: A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea...
May 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27630637/subcutaneous-phaeohyphomycosis-due-to-pyrenochaeta-romeroi-mimicking-a-synovial-cyst
#8
Aurélien Dinh, Bruno Levy, Frédérique Bouchand, Benjamin Davido, Clara Duran, Marin Cristi, Adrien Felter, Jérôme Salomon, Nawel Ait Ammar
Opportunistic subcutaneous fungal infections are increasing nowadays due to the growing number of medical conditions causing immunosuppression, especially organ transplant. The incidence rate of subcutaneous phaeohyphomycosis is very low. Most studies found are case reports. They showed a wide variation of clinical presentations. Pyrenochaeta romeroi, a fungus from the Dematiaceae group is a saprophyte found in soil and plants and a possible causative agent of phaeohyphomycosis. We present a rare case of subcutaneous phaeohyphomycosis caused by P...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27628109/phaeohyphomycosis-caused-by-rhytidhysteron-rufulum-and-review-of-literature
#9
Jagdish Chander, Nidhi Singla, Reetu Kundu, Uma Handa, Anuradha Chowdhary
Phaeohyphomycosis is caused by a heterogeneous group of mycelial dematiaceous (phaeoid) fungi, which produce melanin pigment. This condition is often confused with chromoblastomycosis. Rhytidhysteron is a dematiaceous fungus, which has been recently found to be causing human infections. Till date only three cases of infection with Rhytidhysteron rufulum have been reported in the literature. All three cases have been from North India. Hereby, we present another two cases where Rhytidhysteron was isolated. Both the patients belonged to Chandigarh (India) and presented with subcutaneous lesions...
September 15, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27570972/genomic-analyses-of-cladophialophora-bantiana-a-major-cause-of-cerebral-phaeohyphomycosis-provides-insight-into-its-lifestyle-virulence-and-adaption-in-host
#10
Chee Sian Kuan, Chun Yoong Cham, Gurmit Singh, Su Mei Yew, Yung-Chie Tan, Pei-Sin Chong, Yue Fen Toh, Nadia Atiya, Shiang Ling Na, Kok Wei Lee, Chee-Choong Hoh, Wai-Yan Yee, Kee Peng Ng
Cladophialophora bantiana is a dematiaceous fungus with a predilection for causing central nervous system (CNS) infection manifesting as brain abscess in both immunocompetent and immunocompromised patients. In this paper, we report comprehensive genomic analyses of C. bantiana isolated from the brain abscess of an immunocompetent man, the first reported case in Malaysia and Southeast Asia. The identity of the fungus was determined using combined morphological analysis and multilocus phylogeny. The draft genome sequence of a neurotrophic fungus, C...
2016: PloS One
https://www.readbyqxmd.com/read/27466308/disseminated-phaeohyphomycosis-with-brain-abscess-and-biliary-invasion-due-to-bipolaris-spp-in-an-immunocompetent-patient
#11
Thomas Frank, Yoshua Esquenazi, Masayuki Nigo, Audrey Wanger, Benjamin Portnoy, Scott Shepard
Bipolaris is a dematiaceous fungus seen in the skin, nasal sinuses, and occasionally in the central nervous system. We present an immunocompetent female with bilateral dural-based abscesses caused by a Bipolaris species. The patient had no involvement of the sinuses with the fungus but was later found to have a significant Bipolaris infection of her biliary tree.
July 2016: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/27456474/subcutaneous-phaeohyphomycosis-caused-by-exophiala-spinifera-in-a-european-patient-with-lymphoma-a-rare-occurrence-case-report-and-literature-review
#12
G Bohelay, S Robert, C Bouges-Michel, M Gerin, A Levy, O Fain, F Caux
Exophiala spinifera is a dematiaceous fungus responsible for rare skin infections presenting as phaeohyphomycosis or chromoblastomycosis which has been primarily reported in tropical and subtropical areas (Asia, South and North America). We report the first case of E. spinifera phaeohyphomycosis in a European patient. The phaeohyphomycosis was limited to the skin, involving the finger of an immunocompromised patient presenting with a large B-cell lymphoma treated by R-mini-CHOP regimen. Remission was initially achieved by surgical excision; however, a local subcutaneous relapse required treatment with itraconazole...
November 2016: Mycoses
https://www.readbyqxmd.com/read/27447296/unusual-ocular-presentations-of-ocular-phaeohyphomycosis
#13
A Maudgil, Z Johnson, N Rogers, H S Mudhar
PurposePhaeohyphomycosis are melanin-containing fungi that rarely infect the eye. We describe three cases of ocular infection with some unusual clinical features.MethodsSeries of three case reports describing three different presentations of phaeohyphomycosis of the eye, their histopathology, and management.ResultsCase 1 mimicked an inflamed conjunctival naevus and was excised on this basis, revealing a conjunctival retention cyst containing pigmented fungal hyphae. Case 2 showed a wooden foreign body incidentally associated with pigmented fungal hyphae, which required treatment with topical antifungal therapy...
July 22, 2016: Eye
https://www.readbyqxmd.com/read/27421992/impairment-of-immune-response-against-dematiaceous-fungi-in-card9-knockout-mice
#14
Weiwei Wu, Ruijun Zhang, Xiaowen Wang, Yinggai Song, Zhengyang Liu, Wenling Han, Ruoyu Li
Dematiaceous fungi are a large group of pathogens that can cause a wide range of diseases in both immunocompetent and immunocompromised hosts. Based on our previous finding of caspase recruitment domain-containing protein 9 (CARD9) mutations in patients with subcutaneous phaeohyphomycosis caused by Phialophora verrucosa (P. verrucosa), we further investigated the exact role of CARD9 in the pathogenesis of phaeohyphomycosis using Card9 knockout (Card9 KO) mice. We showed that Card9 KO mice are profoundly susceptible to P...
October 2016: Mycopathologia
https://www.readbyqxmd.com/read/27408767/cerebral-phaeohyphomycosis-by-fonsecaea-monophora-report-in-a-patient-with-aids-and-a-ring-enhancing-lesion
#15
Prabhava Bagla, Michael Loeffelholz, Lucas S Blanton
Fungal infections are infrequent causes of brain abscesses. Fonsecaea monophora is a dematiaceous fungus that appears to be neurotropic. We report a case of Fonsecaea monophora infection in a patient with acquired immunodeficiency syndrome, and review previous reports of brain abscesses by this organism.
June 2016: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/27374381/cutaneous-involvement-in-the-deep-mycoses-a-literature-review-part-i-subcutaneous-mycoses
#16
J E Carrasco-Zuber, C Navarrete-Dechent, A Bonifaz, F Fich, V Vial-Letelier, D Berroeta-Mauriziano
The deep mycoses are uncommon in our setting. These fungal infections occur mainly in immunosuppressed patients or in tropical climates, and include subcutaneous infections and systemic infections. The skin is always involved in the former. In the first part of this review, we describe the main subcutaneous mycoses: sporotrichosis, chromoblastomycosis, mycetoma, phaeohyphomycosis, hyalohyphomycosis, and lacaziosis. Early recognition and treatment is important, as these infections are frequently associated with high morbidity...
June 30, 2016: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/27310167/concurrent-phaeohyphomycosis-and-ranavirus-infection-in-an-eastern-box-turtle-terrapene-carolina-in-athens-georgia-usa
#17
David Perpiñán, Uriel Blas-Machado, Susan Sánchez, Debra L Miller
An eastern box turtle (Terrapene carolina) was found in a stream in the southeastern US, with a mass affecting the distal right forelimb. The turtle developed complications during hospitalization, including lethargy and oral caseous plaques and eventually died. Postmortem analyses diagnosed a mixed infection of phaeohyphomycosis and Ranavirus.
July 2016: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/27299152/cutaneous-phaeohyphomycosis-caused-by-biatriospora-mackinnonii-in-a-renal-transplant-recipient
#18
Rosemara Hughart, Maria Merrick, Oluwatobi T Adelaja, Susan C Bleasdale, Amanda Harrington, Maria Tsoukas
No abstract text is available yet for this article.
May 2016: JAAD Case Reports
https://www.readbyqxmd.com/read/27287745/subcutaneous-phaeohyphomycosis-caused-by-pyrenochaeta-romeroi-in-a-rheumatoid-arthritis-patient-a-case-report-with-review-of-the-literature
#19
Sonam Sharma, Malini R Capoor, Mukul Singh, Deepti Kiran, Ashish Kumar Mandal
Pyrenochaeta romeroi is a rare fungal agent of chronic, suppurative subcutaneous infections leading to mycetoma. It is an unusual cause of deep, non-mycetomatous infections. We herein present review of the literature along with a case of 61-year-old Indian female with rheumatoid arthritis who developed subcutaneous phaeohyphomycosis caused by Pyrenochaeta romeroi. It posed a diagnostic challenge, as the culture from fine-needle aspirate revealed a non-sporulating dematiaceous mould, which was the only supportive tool for its diagnosis and initiation of the therapy...
October 2016: Mycopathologia
https://www.readbyqxmd.com/read/27274641/a-case-of-phaeohyphomycosis-caused-by-exophiala-lecanii-corni
#20
Kyou Chae Lee, Min Ji Kim, Soo Yuhl Chae, Hae Sook Lee, Yong Hyun Jang, Seok-Jong Lee, Do Won Kim, Weon Ju Lee
No abstract text is available yet for this article.
June 2016: Annals of Dermatology
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