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chromoblastomycosis

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https://www.readbyqxmd.com/read/29136064/chromoblastomycosis-infection-from-a-house-plant
#1
Gerard Smith, Andrea F Chen, Eduardo Weiss
No abstract text is available yet for this article.
October 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29062304/comparative-genomics-of-sibling-species-of-fonsecaea-associated-with-human-chromoblastomycosis
#2
Vania A Vicente, Vinícius A Weiss, Amanda Bombassaro, Leandro F Moreno, Flávia F Costa, Roberto T Raittz, Aniele C Leão, Renata R Gomes, Anamelia L Bocca, Gheniffer Fornari, Raffael J A de Castro, Jiufeng Sun, Helisson Faoro, Michelle Z Tadra-Sfeir, Valter Baura, Eduardo Balsanelli, Sandro R Almeida, Suelen S Dos Santos, Marcus de Melo Teixeira, Maria S Soares Felipe, Mariana Machado Fidelis do Nascimento, Fabio O Pedrosa, Maria B Steffens, Derlene Attili-Angelis, Mohammad J Najafzadeh, Flávio Queiroz-Telles, Emanuel M Souza, Sybren De Hoog
Fonsecaea and Cladophialophora are genera of black yeast-like fungi harboring agents of a mutilating implantation disease in humans, along with strictly environmental species. The current hypothesis suggests that those species reside in somewhat adverse microhabitats, and pathogenic siblings share virulence factors enabling survival in mammal tissue after coincidental inoculation driven by pathogenic adaptation. A comparative genomic analysis of environmental and pathogenic siblings of Fonsecaea and Cladophialophora was undertaken, including de novo assembly of F...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29025254/chromoblastomycosis-of-the-leg
#3
Akash Pramod Sali, Ayushi Sahay
We herein report a case of chromoblastomycosis presenting as a verrucous lesion over the leg. A 56-year-old male patient was a known case of carcinoma larynx and was treated for the same. At presentation to our hospital, the patient, in addition to the recurrent local disease, was suspected to have second primary in the form of verrucous carcinoma of the leg. Histopathological examination of the skin biopsy revealed the presence of characteristic pigmented sclerotic bodies with pseudoepitheliomatous hyperplasia of the overlying epithelium...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/28992604/photodynamic-effects-on-fonsecaea-monophora-conidia-and-raw264-7-in-vitro
#4
Xiuwen Yi, Cindy Fransisca, Ya He, Yinghui Liu, Sha Lu, Liya He, Liyan Xi
Chromoblastomycosis (CBM), one of the neglected tropical diseases, is hard to cure and easy to be recurrent. Many studies suggest that macrophage is involved in the pathogenesis of chromoblastomycosis and the fungicidal effect of 5-Aminolaevulinic Acid-Based Photodynamic Therapy (ALA-PDT) against F. monophora (one of the main causative agent of chromoblastomycosis) has shown great promise. However, the fungicidal ability of ALA-PDT to F. monophora is still controversial and the molecular mechanism and immune mechanism of ALA-PDT against F...
September 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28992137/molecular-identification-of-chromoblastomycosis-clinical-isolates-in-guangdong
#5
Cindy Fransisca, Ya He, Zhiwen Chen, Hongfang Liu, Liyan Xi
No abstract text is available yet for this article.
November 1, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28954095/chromoblastomycosis-tissue-modifications-during-itraconazole-treatment
#6
Kátia Sheylla Malta Purim, Murilo Calvo Peretti, José Fillus, Marcia Olandoski
Background: Histological and mycological changes during itraconazole use have not been totally established in chromoblastomycosis. Objectives: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. Methods: A histological retrospective study of 20 cases of chromoblastomycosis seen at the university hospital at the south of Brazil, during itraconazole 400 mg daily treatment. Patients were classified into two groups: plaque or tumor lesions, and underwent periodic evaluations every four months during three years...
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28774696/neglected-endemic-mycoses
#7
REVIEW
Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inability to work, physical deformities, and amputations...
November 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28771470/chromoblastomycosis-in-india-review-of-169-cases
#8
REVIEW
Reshu Agarwal, Gagandeep Singh, Arnab Ghosh, Kaushal Kumar Verma, Mragnayani Pandey, Immaculata Xess
Chromoblastomycosis (CBM) is a chronic, progressive, cutaneous and subcutaneous fungal infection following the traumatic implantation of certain dematiaceous fungi. The disease has worldwide prevalence with predominant cases reported from humid tropical and subtropical regions of America, Asia, and Africa. Diagnosis is often delayed or misdirected either due to poor degree of clinical suspicions or clinical simulation of dermatological conditions. The infection is not uncommon in India and several case reports from the sub-Himalayan belt and western and eastern coasts of India have been published; however, very few have reviewed the cases...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28753235/study-on-the-organization-of-cellular-elements-in-the-granulomatous-lesion-caused-by-chromoblastomycosis
#9
Renan Minotto, Maria Isabel Albano Edelweiss, Maria Lúcia Scroferneker
BACKGROUND: Chromoblastomycosis is a deep fungal infection characterized by a complex cellular granuloma. The aim of this study was to analyze the arrangement of cells responsible for the granuloma configuration of this disease by semiquantification of the cellular components of chromoblastomycosis skin biopsies. METHODS: The cells of cutaneous biopsies slides from 100 patients with untreated chromoblastomycosis were stained with hematoxylin-eosin and the granuloma cells were evaluated by microscopic examination of the elements of each granuloma and semiquantified the number of cells through its expressivity in crosses and the histopathological variables...
November 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28670680/subcutaneous-mycoses-in-peru-a-systematic-review-and-meta-analysis-for-the-burden-of-disease
#10
Max Carlos Ramírez Soto, German Malaga
BACKGROUND: There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES: This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which fungal species were commonly associated with these mycoses. METHODS: We performed a meta-analysis after a systematic review of the published literature in PubMed, LILACS, and SciELO to estimate the burden of subcutaneous mycoses in 25 regions in Peru...
July 3, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28660464/respiratory-tract-infection-caused-by-fonsecaea-monophora-after-kidney-transplantation
#11
Isabella Barbosa Cleinman, Sarah Santos Gonçalves, Marcio Nucci, Danielle Carvalho Quintella, Márcia Halpern, Tiyomi Akiti, Glória Barreiros, Arnaldo Lopes Colombo, Guilherme Santoro-Lopes
Fonsecaea spp. are melanized fungi which cause most cases of chromoblastomycosis. The taxonomy of this genus has been revised, now encompassing four species, with different pathogenic potential: F. pedrosoi, F. nubica, F. pugnacius, and F. monophora. The latter two species present wider clinical spectrum and have been associated with cases of visceral infection, most often affecting the brain. To our knowledge, this is the first report of proven case of F. monophora respiratory tract infection. A Brazilian 57-year-old-female patient underwent kidney transplantation on January 12, 2013...
June 28, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28579986/hiv-aspartic-peptidase-inhibitors-modulate-surface-molecules-and-enzyme-activities-involved-with-physiopathological-events-in-fonsecaea-pedrosoi
#12
Vanila F Palmeira, Daniela S Alviano, Lys A Braga-Silva, Fátima R V Goulart, Marcela Q Granato, Sonia Rozental, Celuta S Alviano, André L S Santos, Lucimar F Kneipp
Fonsecaea pedrosoi is the main etiological agent of chromoblastomycosis, a recalcitrant disease that is extremely difficult to treat. Therefore, new chemotherapeutics to combat this fungal infection are urgently needed. Although aspartic peptidase inhibitors (PIs) currently used in the treatment of human immunodeficiency virus (HIV) have shown anti-F. pedrosoi activity their exact mechanisms of action have not been elucidated. In the present study, we have investigated the effects of four HIV-PIs on crucial virulence attributes expressed by F...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28543666/high-resolution-melting-analysis-assay-for-identification-of-fonsecaea-species
#13
Minglan Shi, Xiqing Li, Jiao Feng, Shulin Jia, Xing Xiao, Chunmei Chen, Cindy Fransisca, Liyan Xi, Junmin Zhang
BACKGROUND: Chromoblastomycosis (CBM) is a chronic fungal disease. In China, the principle etiologic agent was a group of dematiaceous fungi, including Fonsecaea monophora, Fonsecaea nubica, and Cladophialophora carrionii. Although the Fonsecaea species have similar morphology, their pathogenicity is quite different. This study aims to establish a new solution for early identification of Fonsecaea species because of their distinctive potential infection risk. METHODS: Five reference strains and 35 clinical isolates from patients with CBM, preserved in our laboratory, were used in this study...
May 22, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28541426/erratum-molecular-identification-of-chromoblastomycosis-clinical-isolates-in-guangdong
#14
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28525909/counterfeit-pennies-distinguishing-chromoblastomycosis-from-phaeohyphomycotic-infections
#15
Hadas Skupsky, Jacqueline Junkins-Hopkins
No abstract text is available yet for this article.
June 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28458993/chromoblastomycosis-caused-by-rhinocladiella-similis-case-report
#16
Daiane Heidrich, Gloria M González, Danielle M Pagani, Mauricio Ramírez-Castrillón, Maria Lucia Scroferneker
We report a case of chromoblastomycosis in lesions on the chest and foot. Itraconazole was chosen as the initial treatment for this patient, who was followed up for 8 months before becoming noncompliant. The pathogenic fungal species was identified as Rhinocladiella similis by ITS region sequencing. In vitro analyses indicate that the fungus was sensitive to posaconazole and itraconazole. This report presents R. similis as a new agent of chromoblastomycosis and raises the hypothesis that this species could be more resistant to some antifungals than R...
June 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28396061/-chromomycosis-acquired-in-a-non-tropical-area-a-case-report
#17
M S Ouédraogo, M-D Vignon-Pennamen, M Battistella, A Levy, M Feuilhade de Chauvin, A Petit
BACKGROUND: Chromomycosis, or chromoblastomycosis, is caused by cutaneous inoculation of dematiaceous fungi of telluric or plant origin. It is generally seen in tropical or subtropical zones. Treatment of the condition is known to be complex. Herein we report a case of chromomycosis contracted in a temperate region of Eastern Europe/Central Asia that was effectively treated with oral itraconazole and terbinafine in combination with cryotherapy. PATIENTS AND METHODS: A 44-year-old immunocompetent male subject consulted for a lesion on the buttocks that he had sustained 16 years earlier, and which, although never previously treated, had only become troublesome within the last few months...
April 7, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28355277/modulation-of-the-immune-response-by-fonsecaea-pedrosoi-morphotypes-in-the-course-of-experimental-chromoblastomycosis-and-their-role-on-inflammatory-response-chronicity
#18
Isaque Medeiros Siqueira, Raffael Júnio Araújo de Castro, Luiza Chaves de Miranda Leonhardt, Márcio Sousa Jerônimo, Aluízio Carlos Soares, Tainá Raiol, Christiane Nishibe, Nalvo Almeida, Aldo Henrique Tavares, Christian Hoffmann, Anamelia Lorenzetti Bocca
A common theme across multiple fungal pathogens is their ability to impair the establishment of a protective immune response. Although early inflammation is beneficial in containing the infection, an uncontrolled inflammatory response is detrimental and may eventually oppose disease eradication. Chromoblastomycosis (CBM), a cutaneous and subcutaneous mycosis, caused by dematiaceous fungi, is capable of inducing a chronic inflammatory response. Muriform cells, the parasitic form of Fonsecaea pedrosoi, are highly prevalent in infected tissues, especially in long-standing lesions...
March 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28348446/exploring-the-genomic-diversity-of-black-yeasts-and-relatives-chaetothyriales-ascomycota
#19
M M Teixeira, L F Moreno, B J Stielow, A Muszewska, M Hainaut, L Gonzaga, A Abouelleil, J S L Patané, M Priest, R Souza, S Young, K S Ferreira, Q Zeng, M M L da Cunha, A Gladki, B Barker, V A Vicente, E M de Souza, S Almeida, B Henrissat, A T R Vasconcelos, S Deng, H Voglmayr, T A A Moussa, A Gorbushina, M S S Felipe, C A Cuomo, G Sybren de Hoog
The order Chaetothyriales (Pezizomycotina, Ascomycetes) harbours obligatorily melanised fungi and includes numerous etiologic agents of chromoblastomycosis, phaeohyphomycosis and other diseases of vertebrate hosts. Diseases range from mild cutaneous to fatal cerebral or disseminated infections and affect humans and cold-blooded animals globally. In addition, Chaetothyriales comprise species with aquatic, rock-inhabiting, ant-associated, and mycoparasitic life-styles, as well as species that tolerate toxic compounds, suggesting a high degree of versatile extremotolerance...
March 2017: Studies in Mycology
https://www.readbyqxmd.com/read/28194139/1-10-phenanthroline-5-6-dione-based-compounds-are-effective-in-disturbing-crucial-physiological-events-of-phialophora-verrucosa
#20
Marcela Queiroz Granato, Diego de Souza Gonçalves, Sergio Henrique Seabra, Malachy McCann, Michael Devereux, André Luis Souza Dos Santos, Lucimar Ferreira Kneipp
Phialophora verrucosa is a dematiaceous fungus able to cause chromoblastomycosis, phaeohyphomycosis and mycetoma. All these fungal diseases are extremely difficult to treat and often refractory to the current therapeutic approaches. Therefore, there is an urgent necessity to develop new antifungal agents to combat these mycoses. In this context, the aim of the present work was to investigate the effect of 1,10-phenanthroline-5,6-dione (phendione) and its metal-based derivatives [Ag(phendione)2]ClO4 = ([Ag(phendione)2](+)) and [Cu(phendione)3](ClO4)2...
2017: Frontiers in Microbiology
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