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chromoblastomycosis

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https://www.readbyqxmd.com/read/29313921/image-gallery-uncommon-presentation-of-facial-chromoblastomycosis-caused-by-cladophialophora%C3%A2-carrionii
#1
R-J Wang, R-Y Li
No abstract text is available yet for this article.
December 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/29214105/dermoscopy-of-chromoblastomycosis
#2
Sweta Subhadarshani, Deepika Yadav
Chromoblastomycosis is a chronic cutaneous fungal infection commonly caused by Fonsacea and Cladophialophora spp. Dermoscopy is a non-invasive, real-time diagnostic tool for rapid bedside diagnosis of various inflammatory and non-inflammatory disorders and can be an excellent modality for evaluation of cutaneous mycosis, for which it shows characteristic brown dots, crust, scales and yellow orange structures.
October 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/29209318/the-major-chromoblastomycosis-etiologic-agent-fonsecaea-pedrosoi-activates-the-nlrp3-inflammasome
#3
Raffael Júnio Araújo de Castro, Isaque Medeiros Siqueira, Márcio Sousa Jerônimo, Angelina Maria Moreschi Basso, Paulo Henrique de Holanda Veloso Junior, Kelly Grace Magalhães, Luiza Chaves Leonhardt, Stephan Alberto Machado de Oliveira, Pedro Henrique Bürgel, Aldo Henrique Tavares, Anamélia Lorenzetti Bocca
Fonsecaea pedrosoi is the main etiologic agent of chromoblastomycosis (CBM), one of the most prevalent subcutaneous mycosis in tropical and subtropical countries. CBM is a poorly characterized chronic infection that commonly starts after transcutaneous inoculation of conidia and saprophytic hyphae of F. pedrosoi. Recently, we have shown that unlike conidia, hyphae and muriform cells (the parasitic morphotype) of F. pedrosoi promotes an intense inflammatory response pattern in vivo, which comprises the production of an inflammasome-derived cytokine, IL-1β...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29178398/successful-treatment-of-chromoblastomycosis-of-10-year-duration-due-to-fonsecaea-nubica
#4
Liya He, Jianchi Ma, Xin Mei, Sha Lu, Xiqing Li, Liyan Xi
We report a case of chromoblastomycosis due to presence of large plaque and verrucous hyperplasia lesions on the left upper limb, with elbow abnormal activities, in a 56-year-old male. The diagnosis of chromoblastomycosis was based on gross and microscopic morphologies, histopathological examination and clinical manifestation. Molecular tools were applied to identifying the causative agent: Fonsecaea nubica, which is rarely reported to be associated with chromoblastomycosis. The patient was initially treated orally with terbinafine (250 mg/day) and itraconazole (200 mg/day), subsequently patient received thermotherapy (45-50 °C, 3 hours/day) for one month...
November 25, 2017: Mycoses
https://www.readbyqxmd.com/read/29165523/-chromoblastomycosis-clinical-and-microbiological-characteristics-of-a-neglected-disease
#5
Roberto Ventura-Flores, Virgilio Failoc-Rojas, Heber Silva-Díaz
Chromoblastomycosis is a neglected and chronic fungal disease, mainly affects the subcutaneous tissue in limbs of people with occupational risk. Here, we report two cases of adult patients from tropical regions of northern Peru, affected with chronic erythematous scaly lesions and multiple blackheads, pain, itching and scarring in older areas of injury. Direct examination of the dermal scales showed typical of this disease fumagoides cells; Fonsecaea pedrosoi and Fonsecaea sp. were isolated for at first and second case respectively...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/29151624/biodiversity-and-human-pathogenicity-of-phialophora-verrucosa-and-relatives-in-chaetothyriales
#6
Y Li, J Xiao, G S de Hoog, X Wang, Z Wan, J Yu, W Liu, R Li
Phialophora as defined by its type species P. verrucosa is a genus of Chaetothyriales, and a member of the group known as 'black yeasts and relatives'. Phialophora verrucosa has been reported from mutilating human infections such as chromoblastomycosis, disseminated phaeohyphomycosis and mycetoma, while morphologically similar fungi are rather commonly isolated from the environment. Phenotypes are insufficient for correct species identification, and molecular data have revealed significant genetic variation within the complex of species currently identified as P...
June 2017: Persoonia
https://www.readbyqxmd.com/read/29136064/chromoblastomycosis-infection-from-a-house-plant
#7
Gerard Smith, Andrea F Chen, Eduardo Weiss
No abstract text is available yet for this article.
October 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29062304/comparative-genomics-of-sibling-species-of-fonsecaea-associated-with-human-chromoblastomycosis
#8
Vania A Vicente, Vinícius A Weiss, Amanda Bombassaro, Leandro F Moreno, Flávia F Costa, Roberto T Raittz, Aniele C Leão, Renata R Gomes, Anamelia L Bocca, Gheniffer Fornari, Raffael J A de Castro, Jiufeng Sun, Helisson Faoro, Michelle Z Tadra-Sfeir, Valter Baura, Eduardo Balsanelli, Sandro R Almeida, Suelen S Dos Santos, Marcus de Melo Teixeira, Maria S Soares Felipe, Mariana Machado Fidelis do Nascimento, Fabio O Pedrosa, Maria B Steffens, Derlene Attili-Angelis, Mohammad J Najafzadeh, Flávio Queiroz-Telles, Emanuel M Souza, Sybren De Hoog
Fonsecaea and Cladophialophora are genera of black yeast-like fungi harboring agents of a mutilating implantation disease in humans, along with strictly environmental species. The current hypothesis suggests that those species reside in somewhat adverse microhabitats, and pathogenic siblings share virulence factors enabling survival in mammal tissue after coincidental inoculation driven by pathogenic adaptation. A comparative genomic analysis of environmental and pathogenic siblings of Fonsecaea and Cladophialophora was undertaken, including de novo assembly of F...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29025254/chromoblastomycosis-of-the-leg
#9
Akash Pramod Sali, Ayushi Sahay
We herein report a case of chromoblastomycosis presenting as a verrucous lesion over the leg. A 56-year-old male patient was a known case of carcinoma larynx and was treated for the same. At presentation to our hospital, the patient, in addition to the recurrent local disease, was suspected to have second primary in the form of verrucous carcinoma of the leg. Histopathological examination of the skin biopsy revealed the presence of characteristic pigmented sclerotic bodies with pseudoepitheliomatous hyperplasia of the overlying epithelium...
2017: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/28992604/photodynamic-effects-on-fonsecaea-monophora-conidia-and-raw264-7-in-vitro
#10
Xiuwen Yi, Cindy Fransisca, Ya He, Yinghui Liu, Sha Lu, Liya He, Liyan Xi
Chromoblastomycosis (CBM), one of the neglected tropical diseases, is hard to cure and easy to be recurrent. Many studies suggest that macrophage is involved in the pathogenesis of chromoblastomycosis and the fungicidal effect of 5-Aminolaevulinic Acid-Based Photodynamic Therapy (ALA-PDT) against F. monophora (one of the main causative agent of chromoblastomycosis) has shown great promise. However, the fungicidal ability of ALA-PDT to F. monophora is still controversial and the molecular mechanism and immune mechanism of ALA-PDT against F...
September 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28992137/molecular-identification-of-chromoblastomycosis-clinical-isolates-in-guangdong
#11
Cindy Fransisca, Ya He, Zhiwen Chen, Hongfang Liu, Liyan Xi
No abstract text is available yet for this article.
November 1, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28954095/chromoblastomycosis-tissue-modifications-during-itraconazole-treatment
#12
Kátia Sheylla Malta Purim, Murilo Calvo Peretti, José Fillus, Marcia Olandoski
Background: Histological and mycological changes during itraconazole use have not been totally established in chromoblastomycosis. Objectives: To evaluate tissue modifications in chromoblastomycosis carriers under itraconazole treatment. Methods: A histological retrospective study of 20 cases of chromoblastomycosis seen at the university hospital at the south of Brazil, during itraconazole 400 mg daily treatment. Patients were classified into two groups: plaque or tumor lesions, and underwent periodic evaluations every four months during three years...
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28774696/neglected-endemic-mycoses
#13
REVIEW
Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inability to work, physical deformities, and amputations...
November 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28771470/chromoblastomycosis-in-india-review-of-169-cases
#14
REVIEW
Reshu Agarwal, Gagandeep Singh, Arnab Ghosh, Kaushal Kumar Verma, Mragnayani Pandey, Immaculata Xess
Chromoblastomycosis (CBM) is a chronic, progressive, cutaneous and subcutaneous fungal infection following the traumatic implantation of certain dematiaceous fungi. The disease has worldwide prevalence with predominant cases reported from humid tropical and subtropical regions of America, Asia, and Africa. Diagnosis is often delayed or misdirected either due to poor degree of clinical suspicions or clinical simulation of dermatological conditions. The infection is not uncommon in India and several case reports from the sub-Himalayan belt and western and eastern coasts of India have been published; however, very few have reviewed the cases...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28753235/study-on-the-organization-of-cellular-elements-in-the-granulomatous-lesion-caused-by-chromoblastomycosis
#15
Renan Minotto, Maria Isabel Albano Edelweiss, Maria Lúcia Scroferneker
BACKGROUND: Chromoblastomycosis is a deep fungal infection characterized by a complex cellular granuloma. The aim of this study was to analyze the arrangement of cells responsible for the granuloma configuration of this disease by semiquantification of the cellular components of chromoblastomycosis skin biopsies. METHODS: The cells of cutaneous biopsies slides from 100 patients with untreated chromoblastomycosis were stained with hematoxylin-eosin and the granuloma cells were evaluated by microscopic examination of the elements of each granuloma and semiquantified the number of cells through its expressivity in crosses and the histopathological variables...
November 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28670680/subcutaneous-mycoses-in-peru-a-systematic-review-and-meta-analysis-for-the-burden-of-disease
#16
Max Carlos Ramírez Soto, German Malaga
BACKGROUND: There is a worrying lack of epidemiological data on the geographical distribution and burden of subcutaneous mycoses in Peru, hindering the implementation of surveillance and control programs. OBJECTIVES: This study aimed to estimate the disease burden of subcutaneous mycoses in Peru and identify which fungal species were commonly associated with these mycoses. METHODS: We performed a meta-analysis after a systematic review of the published literature in PubMed, LILACS, and SciELO to estimate the burden of subcutaneous mycoses in 25 regions in Peru...
July 3, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28660464/respiratory-tract-infection-caused-by-fonsecaea-monophora-after-kidney-transplantation
#17
Isabella Barbosa Cleinman, Sarah Santos Gonçalves, Marcio Nucci, Danielle Carvalho Quintella, Márcia Halpern, Tiyomi Akiti, Glória Barreiros, Arnaldo Lopes Colombo, Guilherme Santoro-Lopes
Fonsecaea spp. are melanized fungi which cause most cases of chromoblastomycosis. The taxonomy of this genus has been revised, now encompassing four species, with different pathogenic potential: F. pedrosoi, F. nubica, F. pugnacius, and F. monophora. The latter two species present wider clinical spectrum and have been associated with cases of visceral infection, most often affecting the brain. To our knowledge, this is the first report of proven case of F. monophora respiratory tract infection. A Brazilian 57-year-old-female patient underwent kidney transplantation on January 12, 2013...
December 2017: Mycopathologia
https://www.readbyqxmd.com/read/28579986/hiv-aspartic-peptidase-inhibitors-modulate-surface-molecules-and-enzyme-activities-involved-with-physiopathological-events-in-fonsecaea-pedrosoi
#18
Vanila F Palmeira, Daniela S Alviano, Lys A Braga-Silva, Fátima R V Goulart, Marcela Q Granato, Sonia Rozental, Celuta S Alviano, André L S Santos, Lucimar F Kneipp
Fonsecaea pedrosoi is the main etiological agent of chromoblastomycosis, a recalcitrant disease that is extremely difficult to treat. Therefore, new chemotherapeutics to combat this fungal infection are urgently needed. Although aspartic peptidase inhibitors (PIs) currently used in the treatment of human immunodeficiency virus (HIV) have shown anti-F. pedrosoi activity their exact mechanisms of action have not been elucidated. In the present study, we have investigated the effects of four HIV-PIs on crucial virulence attributes expressed by F...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28543666/high-resolution-melting-analysis-assay-for-identification-of-fonsecaea-species
#19
Minglan Shi, Xiqing Li, Jiao Feng, Shulin Jia, Xing Xiao, Chunmei Chen, Cindy Fransisca, Liyan Xi, Junmin Zhang
BACKGROUND: Chromoblastomycosis (CBM) is a chronic fungal disease. In China, the principle etiologic agent was a group of dematiaceous fungi, including Fonsecaea monophora, Fonsecaea nubica, and Cladophialophora carrionii. Although the Fonsecaea species have similar morphology, their pathogenicity is quite different. This study aims to establish a new solution for early identification of Fonsecaea species because of their distinctive potential infection risk. METHODS: Five reference strains and 35 clinical isolates from patients with CBM, preserved in our laboratory, were used in this study...
May 22, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28541426/erratum-molecular-identification-of-chromoblastomycosis-clinical-isolates-in-guangdong
#20
(no author information available yet)
No abstract text is available yet for this article.
November 1, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
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