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Gadoxetic acid

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https://www.readbyqxmd.com/read/28902723/evaluation-of-transient-motion-during-gadoxetic-acid-enhanced-multiphasic-liver-magnetic-resonance-imaging-using-free-breathing-golden-angle-radial-sparse-parallel-magnetic-resonance-imaging
#1
Jeong Hee Yoon, Jeong Min Lee, Mi Hye Yu, Bo Yun Hur, Robert Grimm, Kai Tobias Block, Hersh Chandarana, Berthold Kiefer, Yohan Son
OBJECTIVES: The aims of this study were to observe the pattern of transient motion after gadoxetic acid administration including incidence, onset, and duration, and to evaluate the clinical feasibility of free-breathing gadoxetic acid-enhanced liver magnetic resonance imaging using golden-angle radial sparse parallel (GRASP) imaging with respiratory gating. MATERIALS AND METHODS: In this institutional review board-approved prospective study, 59 patients who provided informed consents were analyzed...
September 11, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28886231/gadoxetic-acid-enhanced-mri-outperformed-mdct-in-diagnosing-small-hepatocellular-carcinoma-a-meta-analysis
#2
Xijiao Liu, Hanyu Jiang, Jie Chen, You Zhou, Zixing Huang, Bin Song
Early detection of small hepatocellular carcinoma (HCC) lesions can improve long-term patient survival. A systematic review and meta-analysis of the diagnostic performance of gadoxetic acid disodium-enhanced magnetic resonance imaging (Gd-EOB-DTPA-enhanced MRI) and multidetector computed tomography (MDCT) was performed in diagnosing small HCCs measuring up to 2 cm(≤2cm). Two investigators searched multiple databases for studies in which the performances of either Gd-EOB-DTPA-enhanced MRI or MDCT were reported with sufficient data to construct 2 × 2 contingency tables for diagnosing HCCs up to 2 cm on a per-lesion or per-patient level...
September 8, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28879422/differentiating-primary-hepatic-angiosarcomas-from-hemangiomatosis-and-epithelioid-hemangioendotheliomas-using-gadoxetic-acid-enhanced-and-diffusion-weighted-mr-imaging
#3
Jung Wook Seo, Seong Hyun Kim, Ah Yeong Kim, Woo Kyoung Jeong, Ji Young Woo, Won Jeong Park
OBJECTIVES: To assess the value of gadoxetic acid-enhanced and diffusion-weighted (DW) magnetic resonance (MR) imaging for differentiating primary hepatic angiosarcomas from hemangiomatosis and epithelioid hemangioendotheliomas (EHEs). METHODS: We reviewed MR images of seven patients with pathologically determined hepatic angiosarcomas, 11 patients with hemangiomatosis, and five patients with EHEs. Two radiologists assessed morphologic features, signal intensity (SI), enhancement patterns, and the presence of diffusion restriction by consensus and compared between angiosarcoma vs hemangiomatosis and angiosarcoma vs EHEs...
September 6, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28816953/peritumoral-decreased-uptake-area-of-gadoxetic-acid-enhanced-magnetic-resonance-imaging-and-tumor-recurrence-after-surgical-resection-in-hepatocellular-carcinoma-a-strobe-compliant-article
#4
Seung Kak Shin, Yun Soo Kim, Young Sup Shim, Seung Joon Choi, So Hyun Park, Dong Hae Jung, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim
Recently, it has been suggested that peritumoral decreased uptake area (PDUA) in the hepatobiliary phase (HBP) of gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) was associated with vascular invasion in hepatocellular carcinoma (HCC). We aimed to investigate correlations between microvascular invasion and PDUA, and elucidate the predictability of PDUA for tumor recurrence after resection.We retrospectively analyzed clinicopathological and radiological data from 126 consecutive patients with single HCC ≤5 cm without macrovascular invasion who underwent preoperative Gd-EOB-DTPA-enhanced MRI and surgical resection...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28798287/non-hypervascular-hypointense-nodules-on-hepatocyte-phase-gadoxetic-acid-enhanced-mr-images-transformation-of-mr-hepatobiliary-hypointense-nodules-into-hypervascular-hepatocellular-carcinomas
#5
Yun Ku Cho, Ju Won Kim, Mi Young Kim, Hyeon Je Cho
Background/Aims: The annual risk of transformation of non-hypervascular magnetic resonance (MR) hepatobiliary phase imaging (HBPI) hypointense nodules into hypervascular hepatocellular carcinomas (HCCs) was evaluated. Methods: Cirrhotic patients with non-hypervascular HBPI hypointense nodules were retrospectively analyzed if they were diagnosed as HCC and MR followed up longer than 1 year during the period from January 2010 to October 2016 with regular intervals of 3 to 6 months...
August 14, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28796732/is-mri-of-the-liver-needed-during-routine-preoperative-workup-for-colorectal-cancer
#6
Sung Il Kang, Duck-Woo Kim, Jai Young Cho, Jihoon Park, Kyung Ho Lee, Il Tae Son, Heung-Kwon Oh, Sung-Bum Kang
BACKGROUND: The clinical efficacy of gadoxetic acid-enhanced liver MRI as a routine preoperative procedure for all patients with colorectal cancer remains unclear. OBJECTIVE: The purpose of this study was to evaluate the efficacy of preoperative gadoxetic acid-enhanced liver MRI for the diagnosis of liver metastasis in patients with colorectal cancer. DESIGN: This was a retrospective analysis from a prospective cohort database. SETTINGS: All of the patients were from a subspecialty practice at a tertiary referral hospital...
September 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28761907/feasibility-and-reproducibility-of-liver-surface-nodularity-quantification-for-the-assessment-of-liver-cirrhosis-using-ct-and-mri
#7
Grace C Lo, Cecilia Besa, Michael J King, Martin Kang, Ashley Stueck, Swan Thung, Mathilde Wagner, Andrew D Smith, Bachir Taouli
PURPOSE: To assess intra-observer, inter-observer and inter-modality (CT vs. MRI) reproducibility of liver surface nodularity (LSN) scores measured with software used for detection of liver fibrosis. METHODS: This IRB-approved retrospective study included patients with both abdominal CT and MRI within 6 months of histopathologic sampling. Two independent observers used post-processing software to quantify LSN scores on axial non-contrast CT (NCT), axial contrast-enhanced CT (CECT), axial T2-weighted (T2W) HASTE, and axial and coronal post-gadoxetic acid T1-weighted (T1W) images obtained during the hepatobiliary phase (HBP)...
2017: European Journal of Radiology Open
https://www.readbyqxmd.com/read/28760631/prospective-comparison-of-gadoxetic-acid-enhanced-liver-mri-and-contrast-enhanced-ct-with-histopathological-correlation-for-preoperative-detection-of-colorectal-liver-metastases-following-chemotherapy-and-potential-impact-on-surgical-plan
#8
Kartik S Jhaveri, Sandra E Fischer, Hooman Hosseini-Nik, Boraiah Sreeharsha, Ravi J Menezes, Steven Gallinger, Carol-Anne E Moulton
OBJECTIVE: To prospectively compare the diagnostic performance of gadoxetic acid-enhanced MRI (EOB-MRI) and contrast-enhanced CT (CECT) for preoperative detection of colorectal liver metastases (CRLM) following chemotherapy and to evaluate the potential change in the hepatic resection plan. METHODS: 51 patients with CRLM treated with preoperative chemotherapy underwent liver imaging by EOB-MRI and CECT prospectively. Two independent blinded readers characterized hepatic lesions on each imaging modality using a 5-point scoring system...
July 28, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28760004/hepatocellular-carcinoma-with-central-scar-on-gadoxetic-acid-enhanced-and-diffusion-weighted-magnetic-resonance-imaging
#9
Sol Bee Han, Young Kon Kim, Ji Hye Min, Sang Yun Ha, Woo Kyung Jeong, Won Jae Lee
Background Central scars are rarely reported in conventional hepatocellular carcinoma (HCC). The presence of central scars on imaging might lead to erroneous diagnosis of hepatic tumors. Purpose To determine imaging features of HCC with central scars on magnetic resonance imaging (MRI) including gadoxetic acid-enhanced and diffusion-weighted imaging (DWI). Material and Methods Fifty-one patients with 51 surgically confirmed HCCs with central scars (fibrotic scar: n = 50; myxoid scar: n = 1; range = 1...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28755071/erratum-to-hepatocellular-carcinoma-detection-diagnostic-performance-of-a-simulated-abbreviated-mri-protocol-combining-diffusion-weighted-and-t1-weighted-imaging-at-the-delayed-phase-post-gadoxetic-acid
#10
Cecilia Besa, Sara Lewis, Pari V Pandharipande, Jagpreet Chhatwal, Amita Kamath, Nancy Cooper, Ashley Knight-Greenfield, James S Babb, Paolo Boffetta, Norma Padron, Claude B Sirlin, Bachir Taouli
No abstract text is available yet for this article.
July 28, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28746206/association-between-relative-liver-enhancement-on-gadoxetic-acid-enhanced-magnetic-resonance-images-and-histologic-grade-of-hepatocellular-carcinoma
#11
Young-Joo Jin, Soon Gu Cho, Kun Young Lee, Joon Mee Kim, Jin Woo Lee
We evaluated the association between histologic grade of hepatocellular carcinoma (HCC) and degree of HCC enhancement on Gd-EOB-DTPA (Gadoxetic acid, Primovist)-enhanced magnetic resonance images (MRI) in HCC patients.A total of 121 patients who underwent curative surgical resection for HCC at our institution between January 2012 and March 2015 were retrospectively analyzed. Gadoxetic acid enhanced MRI was performed in all patients before surgery. Signal intensities of HCC and peri-HCC areas were measured using regions of interest...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28742376/hypervascular-transformation-of-hypovascular-hypointense-nodules-in-the-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri-a-systematic-review-and-meta-analysis
#12
Chong Hyun Suh, Kyung Won Kim, Junhee Pyo, Jayoun Lee, So Yeon Kim, Seong Ho Park
OBJECTIVE: The purpose of this study is to evaluate the outcomes of hypovascular hypointense nodules in the hepatobiliary phase of gadoxetic acid-enhanced MRI and the risk factors for the hypervascular transformation of the nodules through a systematic review and meta-analysis. MATERIALS AND METHODS: We searched the Ovid-MEDLINE and EMBASE databases for published studies of hypovascular hypointense nodules in patients with chronic liver disease. The pooled proportions of the overall and cumulative incidence rates at 1, 2, and 3 years for the transformation of hypovascular hypointense nodules into hypervascular hepatocellular carcinomas (HCCs) were assessed by using random-effects modeling...
July 25, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28731815/reply-to-biliopancreatic-reflux-shown-on-gadoxetic-acid-enhanced-mri
#13
COMMENT
Reiji Sugita, Kei Ito, Yutaka Noda
No abstract text is available yet for this article.
August 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28731814/biliopancreatic-reflux-shown-on-gadoxetic-acid-enhanced-mri
#14
COMMENT
Ali Devrim Karaosmanoglu, Musturay Karcaaltincaba
No abstract text is available yet for this article.
August 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28726119/a-cost-effectiveness-analysis-of-the-diagnostic-strategies-for-differentiating-focal-nodular-hyperplasia-from-hepatocellular-adenoma
#15
Chong Hyun Suh, Kyung Won Kim, Seong Ho Park, Sangjin Shin, Jeonghoon Ahn, Junhee Pyo, Atul B Shinagare, Katherine M Krajewski, Nikhil H Ramaiya
OBJECTIVES: We evaluated the cost-effectiveness of a gadoxetic acid-enhanced MRI (EOB-MRI) strategy compared with conventional MRI strategy and biopsy to differentiate focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA). METHODS: A decision tree model was constructed to compare the cost-effectiveness of EOB-MRI, conventional MRI with extracellular contrast agents, and biopsy as the initial diagnostic modality in patients with incidentally detected focal liver lesions suspected of being FNH or HCA...
July 19, 2017: European Radiology
https://www.readbyqxmd.com/read/28723741/characterization-of-small-%C3%A2-3%C3%A2-cm-hepatic-lesions-with-atypical-enhancement-feature-and-hypointensity-in-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri-in-cirrhosis-a-stard-compliant-article
#16
Seung Kak Shin, Yun Soo Kim, Seung Joon Choi, Young Sup Shim, Dong Hae Jung, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim
It is difficult to characterize the nodular lesions in cirrhotic liver if typical enhancement pattern is not present on dynamic contrast-enhanced imagings. Although the signal intensity of the hepatobiliary phase in gadoxetic acid-enhanced magnetic resonance imaging (MRI) is helpful for characterization of the lesions, some dysplastic nodules may also exhibit low signal intensity in the hepatobiliary phase. We aimed to assess the usefulness of gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI including diffusion-weighted imaging (DWI) for differentiation between atypical small hepatocellular carcinomas (HCCs) and dysplastic nodules showing low signal intensity (SI) in the hepatobiliary phase, and to evaluate the MRI findings in determining the histological grade of atypical HCCs in patients with cirrhosis...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28709718/gadoxetic-acid-enhanced-high-temporal-resolution-hepatic-arterial-phase-imaging-with-view-sharing-technique-impact-on-the-li-rads-category
#17
Satoshi Goshima, Yoshifumi Noda, Kimihiro Kajita, Nobuyuki Kawai, Hiromi Koyasu, Hiroshi Kawada, Masayuki Matsuo, Kyongtae T Bae
PURPOSE: To evaluate the value of view-sharing multi-hepatic arterial-phase (mHAP) imaging for diagnosis of hypervascular hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Forty-seven consecutive patients with HCC underwent gadoxetic acid-enhanced magnetic resonance (MR) imaging before angiographic and lipiodol CT. Hepatic arterial-phase images were obtained at 5 consecutive phases with shared central k-space of 25%, followed by portal venous, late (2 and 3min), and hepatobiliary phase imaging...
July 3, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28673445/does-injection-flow-rate-have-an-impact-on-arterial-phase-image-degradation-in-liver-mri-a-comparison-of-gadoxetic-acid-versus-gadobutrol
#18
V Cohen-Hallaleh, L Guo, H Hosseini-Nik, N Razaghi Kashani, R Menezes, K Jhaveri
AIM: To evaluate retrospectively the impact of injection flow rate on arterial phase image degradation in liver magnetic resonance imaging (MRI) with gadoxetic acid (Gd-EOB-DTPA) compared to gadobutrol. MATERIALS AND METHODS: Two hundred consecutive patients who had undergone liver MRI were enrolled in this Health Insurance Portability and Accountability Act (HIPAA)-compliant institutional review board (IRB)-approved study and were divided into three groups. Group 1 (50 patients) and 2 (50 patients) had undergone MRI performed with gadoxetic acid (fixed 10 ml) at flow rate of 1 and 2 ml/s, respectively...
June 30, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28670163/t2-mapping-from-multi-echo-dixon-sequence-on-gadoxetic-acid-enhanced-magnetic-resonance-imaging-for-the-hepatic-fat-quantification-can-it-be-used-for-hepatic-function-assessment
#19
Hyunsuk Yoo, Jeong Min Lee, Jeong Hee Yoon, Hyo-Jin Kang, Sang Min Lee, Hyun Kyung Yang, Joon Koo Han
OBJECTIVE: To evaluate the diagnostic value of T2(*) mapping using 3D multi-echo Dixon gradient echo acquisition on gadoxetic acid-enhanced liver magnetic resonance imaging (MRI) as a tool to evaluate hepatic function. MATERIALS AND METHODS: This retrospective study was approved by the IRB and the requirement of informed consent was waived. 242 patients who underwent liver MRIs, including 3D multi-echo Dixon fast gradient-recalled echo (GRE) sequence at 3T, before and after administration of gadoxetic acid, were included...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28659180/multiparametric-imaging-for-detection-and-characterization-of-hepatocellular-carcinoma-using-gadoxetic-acid-enhanced-mri-and-perfusion-ct-which-parameters-work-best
#20
Mustafa Kurucay, Christopher Kloth, Sascha Kaufmann, Konstantin Nikolaou, Hans Bösmüller, Marius Horger, Wolfgang M Thaiss
BACKGROUND: MRI and perfusion-CT (PCT) are both useful imaging techniques for detection and characterization of liver lesions. The aim of this study was to compare the diagnostic accuracy of imaging parameters derived from PCT and gadoxetic acid-enhanced MRI in patients with hepatocellular carcinoma (HCC). METHODS: 36 patients with liver cirrhosis and a total of 67 lesions referred to our hospital for multi-parametric diagnosis of HCC-suspected liver lesions in the setting of liver cirrhosis were prospectively enrolled and underwent PCT and MRI...
June 28, 2017: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
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