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https://www.readbyqxmd.com/read/28547764/visibility-of-focal-liver-lesions-comparison-between-kupffer-phase-of-ceus-with-sonazoid-and-hepatobiliary-phase-of-gadoxetic-acid-enhanced-mri
#1
Woo Young Yang, Hee Sun Park, Young Jun Kim, Mi Hye Yu, Sung Il Jung, Hae Jeong Jeon
BACKGROUND: To investigate the agreement between Kupffer phase of Sonazoid contrast-enhanced sonography (CEUS) and hepatobiliary phase of gadoxetic acid-enhanced MRI in the evaluation of focal liver lesions (FLLs). METHODS: One hundred fifty-four FLLs in 154 patients who underwent both Sonazoid CEUS and gadoxetic acid-enhanced liver MRI were included in this retrospective study. FLL visibility on the Kupffer-phase images was graded as one (invisible or isoenhancing), two (vaguely visible or vaguely hypoenhancing), or three (clearly visible or clearly hypoenhancing), and that on the hepatobiliary-phase images of MRI was graded as one (invisible or hyper/isointense), two (vaguely visible or weakly hypointense), or three (clearly visible or strongly hypointense)...
May 26, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28547117/non-hypervascular-hypointense-nodules-at-gadoxetic-acid-mri-hepatocellular-carcinoma-risk-assessment-with-emphasis-on-the-role-of-diffusion-weighted-imaging
#2
Chiara Briani, Marco Di Pietropaolo, Massimo Marignani, Francesco Carbonetti, Paola Begini, Vincenzo David, Elsa Iannicelli
INTRODUCTION AND AIM: In cirrhotic patients, the characterization of hypovascular nodules, hypointense on hepatobiliary phase gadoxetic acid disodium-enhanced magnetic resonance images (Gd-EOB-DTPA-enhanced MRI), is essential to look for the proper approach strategy. Our objective was to evaluate the imaging features and risk assessment of hypovascular nodules, hypointense on Gd-EOB-DTPA-enhanced MRI, focusing on the diagnostic value of diffusion-weighted imaging (DWI). MATERIAL AND METHODS: This prospective study includes 35 patients with 50 hypovascular hypointense nodules...
May 25, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28500365/capsule-septum-and-t2-hyperintense-foci-for-differentiation-between-large-hepatocellular-carcinoma-%C3%A2-5-cm-and-intrahepatic-cholangiocarcinoma-on-gadoxetic-acid-mri
#3
Jiyoung Hwang, Young Kon Kim, Ji Hye Min, Seo-Youn Choi, Woo Kyung Jeong, Seong Sook Hong, Hyun-Joo Kim, Soohyun Ahn, Hyeon Seon Ahn
OBJECTIVE: To determine the added value of capsule, septum, and T2 hyperintense foci for differentiating large hepatocellular carcinoma (HCC; ≥ 5 cm) from intrahepatic cholangiocarcinoma (ICC) using gadoxetic acid MRI. METHODS: The study included 116 patients (94 men, 22 women; mean age, 56.8 years) with surgically confirmed HCCs (n = 87, 5.0-18.0 cm) or ICCs (n = 29, 5.0-14.0 cm) who underwent gadoxetic acid MRI. Three observers independently reviewed MRIs in two sessions, examining enhancement patterns only and then adding capsule, septum, and T2 hyperintense foci...
May 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28492418/clinical-feasibility-of-free-breathing-dynamic-t1-weighted-imaging-with-gadoxetic-acid-enhanced-liver-magnetic-resonance-imaging-using-a-combination-of-variable-density-sampling-and-compressed-sensing
#4
Jeong Hee Yoon, Mi Hye Yu, Won Chang, Jin-Young Park, Marcel Dominik Nickel, Yohan Son, Berthold Kiefer, Jeong Min Lee
OBJECTIVES: The purpose of the study was to investigate the clinical feasibility of free-breathing dynamic T1-weighted imaging (T1WI) using Cartesian sampling, compressed sensing, and iterative reconstruction in gadoxetic acid-enhanced liver magnetic resonance imaging (MRI). MATERIALS AND METHODS: This retrospective study was approved by our institutional review board, and the requirement for informed consent was waived. A total of 51 patients at high risk of breath-holding failure underwent dynamic T1WI in a free-breathing manner using volumetric interpolated breath-hold (BH) examination with compressed sensing reconstruction (CS-VIBE) and hard gating...
May 11, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28488786/gadoxetic-acid-enhanced-magnetic-resonance-imaging-reflects-co-activation-of-%C3%AE-catenin-and-hepatocyte-nuclear-factor-4%C3%AE-in-hepatocellular-carcinoma
#5
Azusa Kitao, Osamu Matsui, Norihide Yoneda, Kazuto Kozaka, Satoshi Kobayashi, Wataru Koda, Tetsuya Minami, Dai Inoue, Kotaro Yoshida, Taro Yamashita, Tatsuya Yamashita, Shuichi Kaneko, Hiroyuki Takamura, Tetsuo Ohta, Hiroko Ikeda, Yasunori Sato, Yasuni Nakanuma, Kenichi Harada, Ryuichi Kita, Toshifumi Gabata
AIM: The aim of this study is to clarify the correlation of the co-activation of β-catenin and hepatocyte nuclear factor (HNF) 4α with the findings of gadoxetic acid enhanced MRI, organic anion transporting polypeptide (OATP) 1B3 expression and histological differentiation grade in hepatocellular carcinoma (HCC). METHODS: Surgically resected 196 HCC in 174 patients were enrolled in this study. HCC were classified into four groups by immunohistochemical expression of β-catenin, glutamine synthetase (GS) and HNF4α: β-catenin/GS (positive: +) HNF4α (+), β-catenin/GS (+) HNF4α (negative: -), β-catenin/GS (-) HNF4α (+) and β-catenin/GS (-) HNF4α (-)...
May 10, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28486977/rapid-cartesian-versus-radial-acquisition-comparison-of-two-sequences-for-hepatobiliary-phase-mri-at-3-tesla-in-patients-with-impaired-breath-hold-capabilities
#6
Johannes Budjan, Philipp Riffel, Melissa M Ong, Stefan O Schoenberg, Ulrike I Attenberger, Daniel Hausmann
BACKGROUND: Hepatocyte-specific gadolinium based contrast agents (HSCA) provide substantial information for the classification of liver lesions in magnetic resonance imaging (MRI). However, breathing artifacts which reduce image quality and diagnostic confidence of hepatobiliary phase acquisitions are regularly observed in clinical routine. The aim of this study was to evaluate two approaches to reduce breathing artifacts for hepatobiliary phase imaging. METHODS: Twenty minutes after administration of a HSCA (gadoxetic acid), a T1-weighted VIBE sequence with radial k-space sampling (radialVIBE, 180 s acquisition time in free breathing) and a highly accelerated Cartesian VIBE with Dixon fat separation (CD-VIBE, CAIPIRINHA acceleration with r = 2 × 2, breath-hold 8-10 s) were acquired in 35 patients (12 female, 57 ± 13 years), who showed breath-holding difficulties in early phases of the examinations...
May 9, 2017: BMC Medical Imaging
https://www.readbyqxmd.com/read/28483680/preoperative-gadoxetic-acid-enhanced-mri-for-predicting-microvascular-invasion-in-patients-with-single-hepatocellular-carcinoma
#7
Sunyoung Lee, Seong Hyun Kim, Ji Eun Lee, Dong Hyun Sinn, Cheol Keun Park
BACKGROUND & AIMS: This study aimed to identify preoperative magnetic resonance (MR) imaging biomarkers for predicting microvascular invasion (MVI) and to determine their diagnostic performance and evaluate whether they are associated with early recurrence after surgery for single hepatocellular carcinoma (HCC). METHODS: The study included 197 patients with surgically resected HCC (≤ 5 cm) who underwent preoperative gadoxetic acid-enhanced MR imaging. Significant MR imaging findings for predicting MVI were identified on univariate and multivariate analyses...
May 5, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28458596/quantitative-measurement-of-hepatic-fibrosis-with-gadoxetic-acid-enhanced-magnetic-resonance-imaging-in-patients-with-chronic-hepatitis-b-infection-a-comparative-study-on-aspartate-aminotransferase-to-platelet-ratio-index-and-fibrosis-4-index
#8
Guy Mok Lee, Youe Ree Kim, Jong Hyun Ryu, Tae-Hoon Kim, Eun Young Cho, Young Hwan Lee, Kwon-Ha Yoon
OBJECTIVE: To quantitatively measure hepatic fibrosis on gadoxetic acid-enhanced magnetic resonance (MR) in chronic hepatitis B (CHB) patients and identify the correlations with aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis-4 index (FIB-4) values. MATERIALS AND METHODS: This study on gadoxetic acid-enhanced 3T MR imaging included 81 patients with CHB infection. To quantitatively measure hepatic fibrosis, MR images were analyzed with an aim to identify inhomogeneous signal intensities calculated from a coefficient of variation (CV) map in the liver parenchyma...
May 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28458595/diagnosis-of-hepatocellular-carcinoma-with-gadoxetic-acid-enhanced-mri-2016-consensus-recommendations-of-the-korean-society-of-abdominal-radiology
#9
REVIEW
(no author information available yet)
Diagnosis of hepatocellular carcinoma (HCC) with gadoxetic acid-enhanced liver magnetic resonance imaging (MRI) poses certain unique challenges beyond the scope of current guidelines. The regional heterogeneity of HCC in demographic characteristics, prevalence, surveillance, and socioeconomic status necessitates different treatment approaches, leading to variations in survival outcomes. Considering the medical practices in Korea, the Korean Society of Abdominal Radiology (KSAR) study group for liver diseases has developed expert consensus recommendations for diagnosis of HCC by gadoxetic acid-enhanced MRI with updated perspectives, using a modified Delphi method...
May 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28441159/application-of-high-speed-t1-sequences-for-high-quality-hepatic-arterial-phase-magnetic-resonance-imaging-intraindividual-comparison-of-single-and-multiple-arterial-phases
#10
Yang Shin Park, Chang Hee Lee, Jeong Woo Kim, Young-Sun Lee, MunYoung Paek, Kyeong Ah Kim
PURPOSE: The aim of this study was to compare intraindividual single and multiple arterial phase acquisitions and evaluate which acquisition method was more advantageous for obtaining high-quality hepatic arterial phase in gadoxetic acid-enhanced liver magnetic resonance imaging (MRI). MATERIALS AND METHODS: Sixty-seven patients who underwent gadoxetic acid-enhanced liver MRIs and had all 3 kinds of acquisitions (single, dual, and triple arterial phases) were retrospectively included...
April 24, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28439650/gadoxetic-acid-disodium-enhanced-mr-imaging-of-cholangiolocellular-carcinoma-of-the-liver-imaging-characteristics-and-histopathological-correlations
#11
Hiroki Haradome, Toshiyuki Unno, Hiroyuki Morisaka, Yusuke Toda, Thomas C Kwee, Hiroshi Kondo, Keiji Sano, Tomoaki Ichikawa, Fukuo Kondo, Masahiko Sugitani, Tadatoshi Takayama
OBJECTIVES: To review the gadoxetic acid disodium (EOB)-enhanced magnetic resonance (MR) imaging features of cholangiolocellular carcinoma (CoCC) of the liver and compare them with those of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). METHODS: EOB-enhanced MR images of 19 patients with CoCC, 23 with ICC, and 51 with HCC were retrospectively evaluated qualitatively and quantitatively. Univariate and multivariate analyses were performed to determine the characteristic MR features of CoCC with histopathological-imaging correlation...
April 24, 2017: European Radiology
https://www.readbyqxmd.com/read/28409358/added-value-of-gadoxetic-acid-enhanced-t1-weighted-magnetic-resonance-cholangiography-for-the-diagnosis-of-post-transplant-biliary-complications
#12
Sonja Kinner, Tilman B Schubert, Adnan Said, Joshua D Mezrich, Scott B Reeder
OBJECTIVES: Biliary complications after liver transplantation (LT) are common. This study aimed to ascertain the value of gadoxetic acid-enhanced T1-weighted (T1w) magnetic resonance cholangiography (MRC) to evaluate anastomotic strictures (AS), non-anastomotic strictures (NAS) and biliary casts (BC). METHODS: Sixty liver-transplanted patients with suspicion of biliary complications and T2w-MRCP and T1w-MRC followed by endoscopic retrograde cholangiopancreatography (ERCP) or percutaneous transhepatic cholangiography (PTC) were analysed...
April 13, 2017: European Radiology
https://www.readbyqxmd.com/read/28398710/additional-values-of-high-resolution-gadoxetic-acid-enhanced-mr-cholangiography-for-evaluating-the-biliary-anatomy-of-living-liver-donors-comparison-with-t2-weighted-mr-cholangiography-and-conventional-gadoxetic-acid-enhanced-mr-cholangiography
#13
Hyo-Jin Kang, Jeong Min Lee, Jeong Hee Yoon, Ijin Joo, Won Chang, Kyung-Suk Suh, Kwang-Woong Lee, Nam-Joon Yi, Joon Koo Han
PURPOSE: To determine the incremental value of small field of view (sFOV) high-resolution (HR) gadoxetic acid-enhanced 3D T1 -weighted (W) magnetic resonance cholangiography (MRC) for evaluating the biliary anatomy of potential living donors by comparing it to T2 W-MRC. MATERIALS AND METHODS: In all, 73 living donor candidates underwent gadoxetic acid-enhanced MRI (3.0T) including three kinds of MRCs: 3D multislice T2 W-MRC, regular FOV (rFOV) (380 × 380mm, resolution 1...
April 11, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28386720/subcentimeter-hypervascular-nodules-with-typical-imaging-findings-of-hepatocellular-carcinoma-on-gadoxetic-acid-enhanced-mri-outcomes-of-early-treatment-and-watchful-waiting
#14
Jung Han Woo, Kyoung Doo Song, Seong Hyun Kim
OBJECTIVES: To compare treatment outcomes of subcentimeter hypervascular nodules at high risk for developing into hepatocellular carcinomas (SHNHR) between early treatment and watchful waiting until progression to overt hepatocellular carcinoma (HCC) groups. METHODS: SHNHRs were defined as subcentimeter hypervascular nodules with the usual imaging features of HCC on gadoxetic acid-enhanced magnetic resonance imaging (MRI). Among 63 patients with 74 SHNHRs, 27 (37 SHNHRs) received early treatment (treatment of < 1 cm nodules), and 36 (37 SHNHRs) underwent watchful waiting until progression to overt HCC...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28374073/liver-imaging-reporting-and-data-system-on-ct-and-gadoxetic-acid-enhanced-mri-with-diffusion-weighted-imaging
#15
Dong Ik Cha, Kyung Mi Jang, Seong Hyun Kim, Tae Wook Kang, Kyoung Doo Song
OBJECTIVES: To assess major imaging features of Liver Imaging Reporting and Data System (LI-RADS) on contrast-enhanced CT and gadoxetic acid-enhanced MRI and to estimate whether the combination of signal intensity favouring HCC on hepatobiliary phase (HBP) and diffusion-weighted images (DWI) can act as a major feature in LI-RADS. METHODS: Four hundred twenty one patients with 445 observations were included. Major features of LI-RADS on CT and MRI as well as HBP and DWI features were assessed...
April 3, 2017: European Radiology
https://www.readbyqxmd.com/read/28368880/critical-questions-regarding-gadolinium-deposition-in-the-brain-and-body-after-injections-of-the-gadolinium-based-contrast-agents-safety-and-clinical-recommendations-in-consideration-of-the-ema-s-pharmacovigilance-and-risk-assessment-committee-recommendation
#16
Val M Runge
For magnetic resonance, the established class of intravenous contrast media is the gadolinium-based contrast agents. In the 3 decades since initial approval, these have proven in general to be very safe for human administration. However, in 2006, a devastating late adverse reaction to administration of the less stable gadolinium-based contrast agents was identified, nephrogenic systemic fibrosis. The result of actions taken by the European Medicines Agency and the US Food and Drug Administration, stratifying the agents by risk and contraindicating specific agents in severe renal dysfunction, has led to no new cases being identified in North America or Europe...
June 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28363694/cost-effectiveness-of-eob-mri-for-hepatocellular-carcinoma-in-japan
#17
Akihiro Nishie, Satoshi Goshima, Hiroki Haradome, Etsuro Hatano, Yasuharu Imai, Masatoshi Kudo, Masanori Matsuda, Utaroh Motosugi, Satoshi Saitoh, Kengo Yoshimitsu, Bruce Crawford, Eliza Kruger, Graeme Ball, Hiroshi Honda
PURPOSE: The objective of the study was to evaluate the cost-effectiveness of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) in the diagnosis and treatment of hepatocellular carcinoma (HCC) in Japan compared with extracellular contrast media-enhanced MRI (ECCM-MRI) and contrast media-enhanced computed tomography (CE-CT) scanning. METHODS: A 6-stage Markov model was developed to estimate lifetime direct costs and clinical outcomes associated with EOB-MRI...
April 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28348578/contrast-enhanced-magnetic-resonance-cholangiography-practical-tips-and-clinical-indications-for-biliary-disease-management
#18
REVIEW
Stefano Palmucci, Federica Roccasalva, Marina Piccoli, Giovanni Fuccio Sanzà, Pietro Valerio Foti, Alfonso Ragozzino, Pietro Milone, Giovanni Carlo Ettorre
Since its introduction, MRCP has been improved over the years due to the introduction of several technical advances and innovations. It consists of a noninvasive method for biliary tree representation, based on heavily T2-weighted images. Conventionally, its protocol includes two-dimensional single-shot fast spin-echo images, acquired with thin sections or with multiple thick slabs. In recent years, three-dimensional T2-weighted fast-recovery fast spin-echo images have been added to the conventional protocol, increasing the possibility of biliary anatomy demonstration and leading to a significant benefit over conventional 2D imaging...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28342102/the-value-of-gadoxetic-acid-enhanced-mri-for-differentiation-between-hepatic-microabscesses-and-metastases-in-patients-with-periampullary-cancer
#19
Seo-Youn Choi, Young Kon Kim, Ji Hye Min, Dong Ik Cha, Woo Kyoung Jeong, Won Jae Lee
OBJECTIVES: We aimed to identify features that differentiate hepatic microabscess from hepatic metastasis on gadoxetic acid-enhanced MRI in patients with periampullary cancer. METHODS: We included 72 patients (31 patients with 83 hepatic microabscesses and 41 patients with 71 hepatic metastases) who had a history of periampullary cancer and underwent gadoxetic acid-enhanced MRI. Image analysis was performed for margin, signal intensity, rim enhancement, perilesional hyperaemia, pattern on DWI and dynamic phases, and size discrepancy between sequences by consensus of two observers...
March 24, 2017: European Radiology
https://www.readbyqxmd.com/read/28292007/magnetic-resonance-imaging-for-colorectal-cancer-metastasis-to-the-liver-comparative-effectiveness-research-for-the-choice-of-contrast-agents
#20
Nieun Seo, Mi-Suk Park, Kyunghwa Han, Kyung Ho Lee, Seong Ho Park, Gi Hong Choi, Jin-Young Choi, Yong Eun Chung, Myeong-Jin Kim
Purpose: This study was conducted to compare the diagnostic performance and early recurrence rate between gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-MRI) and MRI with extracellular contrast agent (ECA-MRI) for evaluating hepatic lesions in colorectal cancer. Materials and Methods: Between 2005 and 2010, 418 colorectal cancer patients with both preoperative computed tomography (CT) and liver MRI were retrospectively reviewed. Image analysis was based on initial radiologic reports, and diagnostic performance was assessed based on the area under the receiver operating characteristic curve (AUROC)...
March 14, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
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