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Molluscum contagiosum

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https://www.readbyqxmd.com/read/29736921/an-unusual-presentation-of-giant-molluscum-contagiosum-diagnosed-on-cytology
#1
Smita Singh, Mitali Swain, Shailaja Shukla, Ram Chander
Molluscum contagiosum (MC) is most frequently a self-limiting benign viral skin disease. Transmitted by direct skin contact, it is characterized by flesh-colored, dome-shaped, umbilicated lesions. Diagnosis of MC is often done clinically, but when needed, biopsy can be performed, in which characteristic Henderson-Patterson bodies, representing intracytoplasmic assemblies of the virus, are pathognomonic. Atypical presentations of MC are rare in immunocompetent individuals and are challenging to diagnose. We report a case of giant MC, presenting as an ulcero-proliferative growth, in neck of an 8-month-old female child...
May 7, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29661638/-anetoderma-secondary-to-molluscum-contagiosum
#2
Benigno Monteagudo, Miguel Cabanillas, Laura Rosende, Elvira León-Muiños
No abstract text is available yet for this article.
April 13, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29599765/herpesviruses-in-the-activated-phosphatidylinositol-3-kinase-%C3%AE-syndrome
#3
REVIEW
Jeffrey I Cohen
The phosphatidylinositol-3-kinase (PI3K)/Akt pathway is important for multiple stages of herpesvirus replication including virus entry, replication, latency, and reactivation. Recently, patients with gain-of-function mutations in the p110δ-catalytic subunit of PI3K or in the p85-regulatory subunit of PI3K have been reported. These patients have constitutively active PI3K with hyperactivation of Akt. They present with lymphoproliferation and often have infections, particularly recurrent respiratory infections and/or severe virus infections...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29582619/oral-echinacea-exerts-complete-clearing-of-multiple-facial-molluscum-contagiosum-in-a-young-black-patient
#4
Annunziata Dattola, Alessandra Ventura, Mauro Mazzeo, Luca Bianchi
No abstract text is available yet for this article.
March 26, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29576186/update-on-the-treatment-of-molluscum-contagiosum-in-children
#5
P Gerlero, Á Hernández-Martín
Molluscum contagiosum is one of the most common viral infections in childhood. It is a benign and usually self-limiting infection, but its treatment in children can be challenging, particularly when the patient presents multiple lesions or when lesions are symptomatic or highly visible. Several treatment options exist. Choice of treatment depends on the number and location of lesions, the prior experience of the treating physician, and the preferences of the child's parents or carers. This article provides an update on treatment options for molluscum contagiosum, with a particular focus on immunocompetent pediatric patients...
March 22, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29575222/use-of-a-disposable-ear-speculum-an-alternative-technique-for-molluscum-contagiosum-curettage
#6
Virginie Kelly, Jerome Coulombe, Isabelle Lavoie
Molluscum contagiosum is a common contagious disease in children characterized by small skin-colored umbilicated papules. Although spontaneous resolution is common, many parents and patients seek treatment. Multiple therapeutic modalities have been described. We present an easy, safe, caregiver-friendly, modified curettage technique using an ear speculum.
May 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29573271/a-study-of-skin-disease-spectrum-occurring-in-angola-phototype-v-vi-population-in-luanda
#7
David A De Luca, Ziv Maianski, Michael Averbukh
BACKGROUND: Prevalence of skin diseases in Luanda (Angola) is unknown, and publications are barely found in the literature. We aim to describe, for the first time, the frequency of skin disease spectrum in phototype V-VI Angolan population in Luanda City. METHODS: We included Fitzpatrick phototype V-VI Angolan patients who consulted the Dermatology Unit in Luanda Medical Center during a 1-year period. Medical information was recovered from the electronic database, and diagnoses were based on ICD-10...
March 24, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29554156/molluscum-contagiosum-in-immunocompromised-patients-aids-presenting-as-molluscum-contagiosum-in-a-patient-with-psoriasis-on-biologic-therapy
#8
William S Kaufman, Christine S Ahn, William W Huang
Molluscum contagiosum (MC) is a common, self-limited cutaneous infection in immunocompetent individuals. However, in immunocompromised individuals the infection often has an atypical presentation and can be difficult to eradicate, making both the diagnosis and treatment challenging. Due to advancements in the management of patients with human immunodeficiency virus (HIV) and cancer, there is a growing population of immunosuppressed individuals, signaling the need for dermatologists to recognize and manage related skin diseases...
February 2018: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29528195/langerhans-cell-histiocytosis-mimicking-molluscum-contagiosum-a-case-series
#9
José Manuel Fernández Armenteros, Nuria Arco Huguet, Veronica Sanmartin Novell, Felip Vilardell Villellas, Ana Velasco Sanchez, Elisa Martró Català, Rosa Maria Martí Laborda, Xavier Soria Gili
Langerhans cell histiocytosis (LCH) is a disorder characterized by accumulation of Langerhans-like cells in one or various organs. A correct staging work-up is essential since there are multiorgan presentations with a poor prognosis. We report three patients with LCH skin lesions mimicking molluscum contagiosum in association with both high and low risk organ involvement. This peculiar cutaneous presentation can be a clue for the diagnosis of LCH, a disease with potentially severe systemic involvement.
March 12, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29479727/efficacy-and-safety-of-topical-application-of-15-and-10-potassium-hydroxide-for-the-treatment-of-molluscum-contagiosum
#10
Concepció Teixidó, Olga Díez, Josep R Marsal, Maria Giner-Soriano, Helena Pera, Mireia Martinez, Gisela Galindo-Ortego, Joan A Schoenenberger, Jordi Real, Ines Cruz, Rosa Morros
BACKGROUND/OBJECTIVES: Molluscum contagiosum is the most common skin infection in children. One topical treatment used for Molluscum contagiosum is potassium hydroxide. The objective of this study was to compare the efficacy of potassium hydroxide topical treatment at different concentrations with that of placebo in terms of complete clearing of Molluscum contagiosum lesions and to assess the safety and tolerance of potassium hydroxide topical treatment. METHODS: This was a double-blind randomized clinical trial of three treatments (potassium hydroxide 10%, potassium hydroxide 15%, placebo) applied once daily up to complete clearing of lesions (maximum duration 60 days) in 53 children aged 2-6 years in primary health care pediatric offices in Catalonia, Spain...
May 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29479224/congenital-molluscum-contagiosum
#11
Iria Neri, Giulia Liberati, Annalucia Virdi, Annalisa Patrizi
No abstract text is available yet for this article.
August 2017: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29419892/autosomal-recessive-hyper-ige-syndrome-in-two-brothers-of-a-chinese-family-with-a-novel-mutation-in-dock8-gene
#12
LETTER
S Wang, W Mou, Z Xu, J Gui, L Ma
No abstract text is available yet for this article.
February 8, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29418015/inverted-follicular-keratoses-of-the-buttocks
#13
Marie Kenney, Elizabeth B Lester, Deborah L Cook
No abstract text is available yet for this article.
May 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29393023/a-comparison-of-the-effect-of-molluscum-contagiosum-virus-mc159-and-mc160-proteins-on-vaccinia-virus-virulence-in-intranasal-and-intradermal-infection-routes
#14
Sunetra Biswas, Geoffrey L Smith, Edward J Roy, Brian Ward, Joanna L Shisler
Molluscum contagiosum virus (MCV) causes persistent, benign skin neoplasm in children and adults. MCV is refractive to growth in standard tissue culture and there is no relevant animal model of infection. Here we investigated whether another poxvirus (vaccinia virus; VACV) could be used to examine MCV immunoevasion protein properties in vivo. The MCV MC159L or MC160L genes, which encode NF-κB antagonists, were inserted into an attenuated VACV lacking an NF-κB antagonist (vΔA49), creating vMC159 and vMC160...
February 2018: Journal of General Virology
https://www.readbyqxmd.com/read/29364534/italian-multicentre-study-found-infectious-and-vaccine-preventable-diseases-in-children-adopted-from-africa-and-recommends-prompt-medical-screening
#15
Elena Chiappini, Mauro Zaffaroni, Martina Bianconi, Giuseppina Veneruso, Nicolino Grasso, Silvia Garazzino, Rosangela Arancio, Piero Valentini, Anna Ficcadenti, Maria Rosalia Da Riol, Simona La Placa, Luisa Galli, Maurizio de Martino, Gianni Bona
AIM: This study evaluated the prevalence of infectious diseases and immunisation status of children adopted from Africa. METHODS: We studied 762 African children referred to 11 Italian paediatric centres in 2009-2015. Clinical and laboratory data were retrospectively collected and analysed. RESULTS: The median age of the children (60.3% males) was 3 years and 6 months, 52.6% came from Ethiopia and 50.1% had at least one infectious disease...
January 24, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29344319/sandalwood-album-oil-as-a-botanical-therapeutic-in-dermatology
#16
REVIEW
Ronald L Moy, Corey Levenson
Many skin conditions and diseases are characterized by inflammation, infection, and hyperplasia. Safe and effective topical treatment options that can be used long-term are needed. Traditional botanical medicines, which are often complex mixtures that exert their biological activities via multiple mechanisms of action, are being studied as potential new active ingredients in dermatology. Sandalwood album oil (SAO), also known as East Indian sandalwood oil (EISO), is an essential oil distilled from the Santalum album tree and has demonstrated biological activity as an anti-inflammatory, anti-microbial, and anti-proliferative agent...
October 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29329128/expanding-the-morphologic-heterogeneity-of-stromal-changes-in-molluscum-contagiosum-infection
#17
Kristen N Ruby, Ann E Perry, Konstantinos Linos
No abstract text is available yet for this article.
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29319288/an-unusual-reaction-to-molluscum-contagiosum
#18
LETTER
Iria Neri, Camilla Loi, Michela Magnano, Paola Sgubbi, Annalisa Patrizi
No abstract text is available yet for this article.
February 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29282454/interventions-for-nongenital-molluscum-contagiosum-in-persons-without-immune-deficiency
#19
Johannes C van der Wouden, Sander Koning, Kenneth A Katz
Clinical Question: How effective and safe are treatments for nongenital molluscum contagiosum in persons without immune deficiency? Bottom Line: Compared with placebo, imiquimod, 5%, cream was not more effective in clearing molluscum contagiosum and caused more local adverse effects, including application site reactions, in children aged 2 to 12 years; because high-quality evidence for other interventions is lacking, allowing for natural resolution of the infection remains a reasonable approach...
February 1, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29241785/cantharidin-for-treatment-of-facial-molluscum-contagiosum-a-retrospective-review
#20
Marla N Jahnke, Sook Hwang, James L Griffith, Tor Shwayder
No abstract text is available yet for this article.
January 2018: Journal of the American Academy of Dermatology
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