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Molluscum contagiosum

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https://www.readbyqxmd.com/read/29145905/-a-girl-with-a-tumour-on-the-thorax
#1
M B Notenboom-Kool, W Opstelten
A healthy 1-year old girl visits her general practitioner with a solitary dome-shaped tumour on her thorax. The lesion is about one cm in diameter and is present since several months. Pathological research reveals a solitary giant molluscum contagiosum. This is a common viral disease of the childhood. In contrast to this case, mollusca contagiosa typically present as several small papules.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29120484/elisa-for-molluscum-contagiosum-virus
#2
Subuhi Sherwani, Mohammed Chowdhury, Joachim J Bugert
Molluscum contagiosum virus (MCV) is a common skin pathogen of children and young adults. Infection with MCV causes benign skin tumors in children and young adults and is mostly self-limiting. In contrast to orthopoxviruses, MCV infections tend to take a subacute clinical course but may persist for up to 12 months. Current numbers for MCV seroprevalence in different geographical areas are based on a variety of historical serological methods from complement fixation assays to MCV ELISAs based on purified MCV virions and MC133 antigen expressed in a Semliki Forest Virus expression system...
November 9, 2017: Current Protocols in Microbiology
https://www.readbyqxmd.com/read/29103323/treatment-of-molluscum-contagiosum-with-an-east-indian-sandalwood-oil-product
#3
Malika Haque, Daniel L Coury
OBJECTIVES: To evaluate the safety and efficacy of an East Indian Sandalwood Oil (EISO) product as a topical treatment for molluscum contagiosum. MATERIALS AND METHODS: Ten subjects ranging in age from 22 months to 29 years were recruited. Subjects were instructed to apply an EISO product to the lesions twice daily. Subjects were monitored every 2-3 weeks during the study and were questioned regarding local or systemic side effects. Assessment of response was recorded by counting lesions and documented by photographs...
November 6, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29027896/molluscum-contagiosum-and-pubic-hair-removal-in-male-patients
#4
Gino Antonio Vena, Nicoletta Cassano
No abstract text is available yet for this article.
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28885709/prenylation-of-viral-proteins-by-enzymes-of-the-host-virus-driven-rationale-for-therapy-with-statins-and-ft-ggt1-inhibitors
#5
REVIEW
Ekaterina S Marakasova, Birgit Eisenhaber, Sebastian Maurer-Stroh, Frank Eisenhaber, Ancha Baranova
Intracellular bacteria were recently shown to employ eukaryotic prenylation system for modifying activity and ensuring proper intracellular localization of their own proteins. Following the same logic, the proteins of viruses may also serve as prenylation substrates. Using extensively validated high-confidence prenylation predictions by PrePS with a cut-off for experimentally confirmed farnesylation of hepatitis delta virus antigen, we compiled in silico evidence for several new prenylation candidates, including IRL9 (CMV) and few other proteins encoded by Herpesviridae, Nef (HIV-1), E1A (human adenovirus 1), NS5A (HCV), PB2 (influenza), HN (human parainfluenza virus 3), L83L (African swine fever), MC155R (molluscum contagiosum virus), other Poxviridae proteins, and some bacteriophages of human associated bacteria...
September 8, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/28884917/molluscum-contagiosum-review-and-update-on-management
#6
REVIEW
Emily Forbat, Firas Al-Niaimi, Faisal R Ali
Molluscum contagiosum (MC) is an infectious dermatosis that commonly presents in children and immunocompromised individuals. Although lesions usually resolve spontaneously after several months, they can be symptomatic and cause psychosocial distress. We review the evidence underlying treatment methods available for MC lesions, including potassium hydroxide, salicylic acid, hydrogen peroxide, retinoids, cantharidin, cryotherapy, curettage, and pulsed dye laser to aid practicing dermatologists in therapy selection...
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28871935/topical-imiquimod-is-an-effective-and-safe-drug-for-molluscum-contagiosum-in-children
#7
George Badavanis, Efstathia Pasmatzi, Alexandra Monastirli, Sophia Georgiou, Dionysios Tsambaos
Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. In adults, the skin lesions are predominantly located in the genital region, whereas in children they are found on the trunk, the extremities, and the face...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28866311/filaggrin-mutations-and-molluscum-contagiosum-skin-infection-in-patients-with-atopic-dermatitis
#8
Sara Manti, Maria Amorini, Caterina Cuppari, Annamaria Salpietro, Francesca Porcino, Salvatore Leonardi, Michele Miraglia Del Giudice, Gianluigi Marseglia, Davide Paolo Caimmi, Carmelo Salpietro
BACKGROUND: Although mutations in the filaggrin (FLG) gene have been reported to predispose patients with atopic dermatitis (AD) skin infection susceptibility, to date, the data reported in the literature are still controversial. OBJECTIVE: To evaluate the role of FLG polymorphisms expression and risk of developing a concomitant Molluscum contagiosum sustained skin infection in the pediatric population with AD. METHODS: A total of 100 children with AD and 97 healthy children were enrolled...
August 30, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28845328/eyelid-molluscum-contagiosum-lesions-in-two-patients-with-unilateral-chronic-conjunctivitis
#9
Şule Serin, Ayşe Bozkurt Oflaz, Pınar Karabağlı, Şansal Gedik, Banu Bozkurt
Molluscum contagiosum (MC) is a viral infection of the skin and mucosal tissues characterized by skin-colored or transparent round nodules with a dimple or pit in the center. The infection is caused by a DNA poxvirus called the MC virus. Although MC generally occurs in children, it has also been reported in immunocompromised and atopic patients. The virus is transmitted by skin contact or sexual intercourse. The lesions disappear spontaneously within several months in most cases. However, excision, cryotherapy, cauterization, topical chemical and antiviral agents, and/or oral cimetidine are used in refractory cases or to accelerate the healing process...
August 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28806866/molecular-screening-and-single-nucleotide-polymorphism-typing-of-molluscum-contagiosum-virus-mcv-from-genital-specimens-between-2012-and-2015
#10
Sedigheh Taghinezhad-S, Amir Hossein Mohseni, Hossein Keyvani, Narges Ghobadi
Background: The present study is the first comprehensive report of the Molluscum contagiosum virus (MCV) in Iran based on the molecular technique for differentiation and typing of the MCV1 and MCV2. Methods: Patients were diagnosed as having tumor-like genital warts less than 5 mm in diameter, and HIV seronegative samples were chosen for this cross-sectional study. TaqMan real-time PCR was used to identify MCV following clinical examination. Typing of the MCV-positive specimens was performed in the SNP A27451G region of MC021L gene...
August 15, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/28805130/melan-a-antibody-cross-reactivity-in-molluscum-contagiosum-bodies
#11
David Creytens
No abstract text is available yet for this article.
August 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28768695/%C3%A2-strontium-ranelate-discontinued
#12
(no author information available yet)
▼ Strontium ranelate discontinued ● Limited treatment options for molluscum contagiosum ● Finasteride drug safety alert ● Does doxycycline delay the next COPD exacerbation? ● Support for WHO standards on reporting clinical trial results ● Delayed antibiotic prescription for lower respiratory tract infections ● Nystatin dose change - much ado about nothing?
August 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28768690/limited-treatment-options-for-molluscum-contagiosum
#13
(no author information available yet)
No abstract text is available yet for this article.
August 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28730670/molluscum-contagiosum-like-presentation-of-langerhans-cell-histiocytosis-a-case-and-review
#14
Matthew S Karpman, Mohammed I AlJasser, Joseph M Lam
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal proliferation of Langerhans cells in the skin. A molluscum-like presentation of cutaneous LCH is rare but important to consider for examination and management. We present an atypical molluscum-like LCH case and review the literature for common features of this unusual presentation.
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28685222/characterization-of-eptesipoxvirus-a-novel-poxvirus-from-a-microchiropteran-bat
#15
Shin-Lin Tu, Yoshinori Nakazawa, Jinxin Gao, Kimberly Wilkins, Nadia Gallardo-Romero, Yu Li, Ginny L Emerson, Darin S Carroll, Chris Upton
The genome of Eptesipoxvirus (EPTV) is the first poxvirus genome isolated from a microbat. The 176,688 nt sequence, which is believed to encompass the complete coding region of the virus, is 67% A+T and is predicted to encode 191 genes. 11 of these genes have no counterpart in GenBank and are therefore unique to EPTV. The presence of a distantly related ortholog of Vaccinia virus F5L in EPTV uncovered a link with fragmented F5L orthologs in Molluscum contagiosum virus/squirrelpox and clade II viruses. Consistent with the unique position of EPTV approximately mid-point between the orthopoxviruses and the clade II viruses, EPTV has 11 genes that are specific to the orthopoxviruses and 13 genes that are typical, if not exclusive, to the clade II poxviruses...
July 6, 2017: Virus Genes
https://www.readbyqxmd.com/read/28667573/urologic-dermatology-a-review
#16
REVIEW
Andrew W Stamm, Kathleen C Kobashi, Ksenija B Stefanovic
PURPOSE OF REVIEW: Genital dermatology represents a challenge to many providers. Though dermatologic lesions involving the genitalia may present to any of a number of practices, ranging from primary care to urology, gynecology, and dermatology, few training programs provide significant training regarding the diagnosis and management of genital dermatologic lesions. The purpose of this review is to provide urologists with an overview of common genital dermatological lesions that may be encountered in a clinic...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28555548/recombination-events-and-variability-among-full-length-genomes-of-co-circulating-molluscum-contagiosum-virus-subtypes-1-and-2
#17
Alberto López-Bueno, Marcos Parras-Moltó, Olivia López-Barrantes, Sylvia Belda, Alí Alejo
Molluscum contagiosum virus (MCV) is the sole member of the Molluscipoxvirus genus and causes a highly prevalent human disease of the skin characterized by the formation of a variable number of lesions that can persist for prolonged periods of time. Two major genotypes, subtype 1 and subtype 2, are recognized, although currently only a single complete genomic sequence corresponding to MCV subtype 1 is available. Using next-generation sequencing techniques, we report the complete genomic sequence of four new MCV isolates, including the first one derived from a subtype 2...
May 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28543922/molluscum-contagiosum-of-the-gluteal-cleft-observations-and-implications-for-management-in-five-children
#18
Joshua R Bakke, Sarah L Stein
Molluscum contagiosum (MC) is a common, self-limited skin infection caused by a double-stranded DNA virus of the family Poxviridae. Although the morphology of the disease is well described, MC presenting at unusual sites can exhibit atypical morphology, resulting in misdiagnosis. This observational, retrospective case series discusses the novel morphology of MC presenting in the intergluteal cleft of five children seen in the outpatient dermatology clinic of an academic medical center. We present this case series to highlight this novel presentation of MC in children and to emphasize a conservative approach to management given the sensitive location and the self-limited nature of the infection...
July 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28528469/multiple-sclerosis-treatment-with-fingolimod-profile-of-non-cardiologic-adverse-events
#19
REVIEW
Yara Dadalti Fragoso
Fingolimod was the first oral medication approved for management of multiple sclerosis and is currently used by tens of thousands patients worldwide. Fingolimod acts via the sphingosine 1-phosphate (S1P) receptor, maintaining peripheral lymphocytes entrapped in the lymph nodes. In consequence, there is a reduction in the infiltration of aggressive lymphocytes into the central nervous system. The drug is safe and effective, and its first hours of use are associated with related to S1P receptors in the heart...
May 20, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28521677/molluscum-contagiosum-an-update
#20
Alexander Kc Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Molluscum contagiosum is a viral cutaneous infection in childhood that occurs worldwide. Physicians should familiarize themselves with this common condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications and, in particular, treatment of molluscum contagiosum. METHODS: A PubMed search was completed in Clinical Queries using the key term "molluscum contagiosum". Patents were searched using the key term "molluscum contagiosum" from www...
May 17, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
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