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https://www.readbyqxmd.com/read/28526551/assessment-of-vertical-ridge-augmentation-in-anterior-aesthetic-zone-using-onlay-xenografts-with-titanium-mesh-versus-the-inlay-bone-grafting-technique-a-randomized-clinical-trial
#1
M Mounir, S Mounir, A A Elfetouh, M A Shaker
The aim of this study was to evaluate the final vertical gain at the deficient anterior maxillary alveolar ridges using onlay bone grafts with titanium mesh versus inlay bone grafting. This was a single institutional randomized comparative clinical trial. The study population included 16 patients, with edentulous anterior maxillary alveolar ridges (40 implant sites) who were presented and treated at the Faculty of Oral and Dental Medicine in Cairo University from September 2013 to August 2015. Selected patients were randomly divided into two equal groups...
May 16, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28526045/standardization-of-platelet-releasate-products-for-clinical-applications-in-cell-therapy-a-mathematical-approach
#2
Francesco Agostini, Jerry Polesel, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Alessandro Da Ponte, Giuseppe Astori, Cristina Durante, Mario Mazzucato
BACKGROUND: Standardized animal-free components are required for manufacturing cell-based medicinal products. Human platelet concentrates are sources of growth factors for cell expansion but such products are characterized by undesired variability. Pooling together single-donor products improves consistency, but the minimal pool sample size was never determined. METHODS: Supernatant rich in growth factors (SRGF) derived from n = 44 single-donor platelet-apheresis was obtained by CaCl2 addition...
May 19, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28526022/a-descriptive-cross-sectional-study-of-medical-student-preferences-for-vodcast-design-format-and-pedagogical-approach
#3
Robin K Pettit, Marjorie Kinney, Lise McCoy
BACKGROUND: Vodcasts (video podcasts) are becoming increasingly popular in medical education. At A.T. Still University School of Osteopathic Medicine in Arizona (ATSU SOMA), vodcasts are an essential component of our blended learning environment, where year 2-4 students train in a contextual setting at community health centers across the U.S. Vodcasts are used far less frequently in our year 1 residential learning environment at the main campus in Arizona, but we are considering moving to significantly more interactive educational experiences with on-demand videos followed by in-class activities...
May 19, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28523827/statistical-model-based-hplc-analytical-method-adjustment-strategy-to-adapt-to-different-sets-of-analytes-in-complicated-samples
#4
Binjun Yan, Xue Bai, Yunjie Sheng, Fanzhu Li
INTRODUCTION: On account of the complicated compositions of the products like traditional Chinese medicines (TCMs) and functional foods, it is a common practice to determine different sets of analytes in the same product for different purposes. OBJECTIVE: To efficiently develop the corresponding HPLC methods, a statistical model based analytical method adjustment (SMB-AMA) strategy was proposed. METHODS: In this strategy, the HPLC data acquired with design of experiments methodology were efficiently utilised to build the retention models for all the analytes and interferences shown in the chromatograms with multivariate statistical modelling methods...
May 19, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28523139/an-overview-of-the-use-of-artificial-neural-networks-in-lung-cancer-research
#5
EDITORIAL
Luca Bertolaccini, Piergiorgio Solli, Alessandro Pardolesi, Antonello Pasini
The artificial neural networks (ANNs) are statistical models where the mathematical structure reproduces the biological organisation of neural cells simulating the learning dynamics of the brain. Although definitions of the term ANN could vary, the term usually refers to a neural network used for non-linear statistical data modelling. The neural models applied today in various fields of medicine, such as oncology, do not aim to be biologically realistic in detail but just efficient models for nonlinear regression or classification...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28523051/prevalence-of-anemia-and-related-factors-among-women-in-turkey
#6
Birsen Karaca Saydam, Rabia Ekti Genc, Fulden Sarac, Esin Ceber Turfan
OBJECTIVE: To determine the prevalence of anemia and related factors among women in Turkey. METHODS: This descriptive study was conducted at the outpatient clinics of the Department of Internal Medicine, Ege University Medical School. Randomly selected women were given questionnaires regarding their socio-demographic and obstetric characteristics. The data were coded and analyzed using SPSS version 17.0 software. Statistical analyses with 95% confidence intervals were considered to be significant if p<0...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522319/association-between-gestational-weight-gain-and-perinatal-outcomes-in-women-with-chronic-hypertension
#7
Lynn M Yee, Aaron B Caughey, Yvonne W Cheng
BACKGROUND: Gestational weight gain above or below the 2009 Institute of Medicine guidelines has been associated with adverse maternal and neonatal outcomes. Although it has been well established that excess gestational weight gain is associated with the development of gestational hypertension and preeclampsia, the relationship between gestational weight gain and adverse perinatal outcomes among women with pregestational (chronic) hypertension is less clear. OBJECTIVE: The objective of this study was to examine the relationship between gestational weight gain above and below IOM guidelines and perinatal outcomes in a large, population-based cohort of women with chronic hypertension...
May 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28522317/the-association-between-cytochrome-p450-3a-progesterone-receptor-polymorphisms-plasma-17-ohpc-concentrations-and-spontaneous-preterm-birth
#8
Martha L Bustos, Steve N Caritis, Kathleen A Jablonski, Uma M Reddy, Yoram Sorokin, John M Thorp, Michael W Varner, Ronald J Wapner, Jay D Iams, Marshall W Carpenter, Alan M Peaceman, Brian M Mercer, Anthony Sciscione, Dwight J Rouse, Susan M Ramin
BACKGROUND: Infants born before 37 weeks' gestation are of public health concern since complications associated with preterm birth are the leading cause of mortality in children under 5 years of age and a major cause of morbidity and lifelong disability. The administration of 17-hydroxyprogesterone caproate (17-OHPC) reduces preterm birth by 33% in women with history spontaneous preterm birth (SPTB). We demonstrated previously that plasma concentrations of 17-OHPC vary widely among pregnant women and that women with 17-OHPC plasma concentrations in the lowest quartile had SPTB rates of 40% vs rates of 25% in those women with higher concentrations...
May 15, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28520198/dynamic-and-steady-state-oxygen-dependent-lung-relaxometry-using-inversion-recovery-ultra-fast-steady-state-free-precession-imaging-at-1-5-t
#9
Grzegorz Bauman, Orso Pusterla, Francesco Santini, Oliver Bieri
PURPOSE: To demonstrate the feasibility of oxygen-dependent relaxometry in human lung using an inversion recovery ultra-fast steady-state free precession (IR-ufSSFP) technique. METHODS: Electrocardiogram-triggered pulmonary relaxometry with IR-ufSSFP was performed in 7 healthy human subjects at 1.5 T. The data were acquired under both normoxic and hyperoxic conditions. In a single breath-hold of less than 9 seconds, 30 transient state IR-ufSSFP images were acquired, yielding longitudinal (T1) and transversal (T2) relaxometry parameter maps using voxel-wise nonlinear fitting...
May 18, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28518168/using-high-resolution-variant-frequencies-to-empower-clinical-genome-interpretation
#10
Nicola Whiffin, Eric Minikel, Roddy Walsh, Anne H O'Donnell-Luria, Konrad Karczewski, Alexander Y Ing, Paul J R Barton, Birgit Funke, Stuart A Cook, Daniel MacArthur, James S Ware
PurposeWhole-exome and whole-genome sequencing have transformed the discovery of genetic variants that cause human Mendelian disease, but discriminating pathogenic from benign variants remains a daunting challenge. Rarity is recognized as a necessary, although not sufficient, criterion for pathogenicity, but frequency cutoffs used in Mendelian analysis are often arbitrary and overly lenient. Recent very large reference datasets, such as the Exome Aggregation Consortium (ExAC), provide an unprecedented opportunity to obtain robust frequency estimates even for very rare variants...
May 18, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28516731/alopecia-areata-hyperactivity-of-the-hypothalamic-pituitary-adrenal-axis-is-a-myth
#11
Beata Bergler-Czop, Bartosz Miziołek, Ligia Brzezińska-Wcisło
INTRODUCTION: Psychological stress is known to cause exacerbation of different skin pathologies including alopecia areata (AA). A hyperactivity of the HPA axis in patients affected by AA (AA-patients) was proposed to be a neuroendocrine response to stress. Still little is known about MSH and cortisol production in AA settings. AIM: The aim of the study was to compare trends in a production of melanocyte-stimulating hormone (MSH) and cortisol in patients with AA-patients and healthy controls...
May 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28515733/stable-internal-reference-genes-for-normalizing-real-time-quantitative-pcr-in-baphicacanthus-cusia-under-hormonal-stimuli-and-uv-irradiation-and-in-different-plant-organs
#12
Yuxiang Huang, Hexin Tan, Jian Yu, Yue Chen, Zhiying Guo, Guoquan Wang, Qinglei Zhang, Junfeng Chen, Lei Zhang, Yong Diao
Baphicacanthus cusia (Nees) Bremek, the plant source for many kinds of drugs in traditional Chinese medicine, is widely distributed in South China, especially in Fujian. Recent studies about B. cusia mainly focus on its chemical composition and pharmacological effects, but further analysis of the plant's gene functions and expression is required to better understand the synthesis of its effective compounds. Real-time quantitative polymerase chain reaction (RT-qPCR) is a powerful method for gene expression analysis...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28515633/association-between-type-2-diabetes-mellitus-and-anthropometric-measurements-a-case-control-study-in-south-india
#13
REVIEW
A Awasthi, C R Rao, D S Hegde, K Rao N
INTRODUCTION: Obesity is a major risk factor for type 2 diabetes mellitus (T2DM). Clinical evidence indicates a stronger association of diabetes with central obesity than general obesity. The present study aimed to compare the association between type 2 diabetes mellitus and different anthropometric measurements and evaluate the usefulness of these measurements in clinical practice. METHODS: A case-control study was done among 102 individuals; of whom 51 cases included diagnosed T2DM (≥ 20 years age) patients attending the Medicine out-patient consultation of a tertiary care hospital and 51 controls who were screen negative for T2DM and recruited from the local community...
March 2017: Journal of Preventive Medicine and Hygiene
https://www.readbyqxmd.com/read/28513854/verification-of-dose-profiles-generated-by-the-convolution-algorithm-of-the-gamma-knife-%C3%A2-radiosurgery-planning-system
#14
Hyun-Tai Chung, Jeong-Hoon Park, Kook Jin Chun
PURPOSE: A convolution algorithm that takes into account electron-density inhomogeneity was recently introduced to calculate dose distributions for the Gamma Knife (GK) Perfexion(™) treatment planning program. The accuracies of the dose distributions computed using the convolution method were assessed using an anthropomorphic phantom and film dosimetry. METHODS: Absorbed-dose distributions inside a phantom (CIRS Radiosurgery Head Phantom, Model 605) were calculated using the convolution method of the GK treatment-planning software (Leksell Gamma Plan(®) version 10...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28513570/a-study-of-the-protective-properties-of-iraqi-olive-leaves-against-oxidation-and-pathogenic-bacteria-in-food-applications
#15
Ammar B Altemimi
There is an ancient and prodigious history of olive trees because of their nutritional, medicinal, and traditional uses. Intensive studies have been conducted on olive leaves because they have many positive and beneficial effects for human health. In this study, different solvents were used to examine the olive leaves for their antioxidant and antimicrobial activities and their possible food applications. The obtained results showed that the amounts of phenolic compounds of the olive leaf were 190.44 ± 0.50, 173 ± 1...
May 17, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28512501/effect-of-traditional-chinese-medicine-product-qiangguyin-on-bone-mineral-density-and-bone-turnover-in-chinese-postmenopausal-osteoporosis
#16
Zhen-Yu Shi, Xin-Gen Zhang, Chun-Wen Li, Kang Liu, Bo-Cheng Liang, Xiao-Lin Shi
Introduction. The aim of this study was to investigate the efficacy of herbal formula QiangGuYin (QGY) in postmenopausal women. Materials and Methods. A total of 240 participants from six clinical centers were randomly to receive alendronate 70 mg/week, QGY granules 20 g/day, and placebo. Primary end points were BMD changes over 6 and 12 months; secondary end points were bone turnover markers changes at 3, 6, 9, and 12 months. Safety was monitored by clinical adverse events reported during the follow-up...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28512360/bullying-behavior-and-mental-health-in-healthcare-and-educational-sectors-in-kaunas-lithuania
#17
Lina Bernotaite, Vilija Malinauskiene, Palmira Leisyte
BACKGROUND: Investigations on workplace bullying in the countries of Eastern Europe are yet not too extensive. The aim of the study has been to identify the most frequent bullying behavior and to explore the associations with psychological distress and post-traumatic stress symptoms in 3 female-dominated occupations in Kaunas, Lithuania. MATERIAL AND METHODS: This crosssectional study employed 517 teachers (response rate (RR) = 71.3%), 174 family physicians (RR = 65...
May 16, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28511659/antiplasmodial-activity-of-indigofera-spicata-root-extract-against-plasmodium-berghei-infection-in-mice
#18
Eshetie Melese Birru, Mestayet Geta, Abyot Endale Gurmu
BACKGROUND: In addition to pharmacovigilance and pharmaco-economic concerns, resistance to anti-malarial medicines has been documented in all classes of anti-malarials and this is further worsened by resistance to common insecticides by malaria vector, which is a major threat to malaria control. As a means of facing the challenges of searching for new anti-malarial agents, the current study focused on evaluation of anti-malarial activity of root extract of Indigofera spicata. METHODS: Chloroquine-sensitive rodent malaria parasite, Plasmodium berghei (ANKA strain) was used to infect the Swiss Albino mice in 4-day suppressive and curative models...
May 16, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28511517/holistic-healing-through-herbs-effectiveness-of-aloe-vera-on-post-extraction-socket-healing
#19
Vijaya Lakshmi Nimma, Harsha Vardhan Talla, Jaya Krishna Bairi, Madhulatha Gopaldas, Haritha Bathula, Sandeep Vangdoth
INTRODUCTION: Advances in the field of alternative medicine has encouraged the use of various natural products for multiple uses in the field of dentistry for treatment of various oral diseases. A natural herbal product is Aloe vera, which has number of benefits with no reported side effects and gaining considerable importance in clinical research. AIM: The aim of this cross-sectional randomized interventional study was to evaluate the effectiveness of Aloe vera in the healing of post extraction sockets...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511475/colour-doppler-evaluation-of-extracranial-carotid-artery-in-patients-presenting-with-acute-ischemic-stroke-and-correlation-with-various-risk-factors
#20
Samrin Haq, Manoj Mathur, Jasvir Singh, Navkiran Kaur, Raminderpal Singh Sibia, Rajesh Badhan
INTRODUCTION: Stroke is defined as an abrupt onset of neurologic deficit due to vascular cause. It is one of the leading causes of mortality and morbidity all over the world making early diagnosis and treatment inevitable. Lesions of extra cranial carotid arteries are implicated in majority of cases of acute ischemic stroke. Carotid Doppler is a non-invasive imaging technique, with sensitivity approaching that of angiography. Computed Tomography (CT) plays a major role to assess the site and nature of the lesion in patients with acute ischemic stroke...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
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