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https://www.readbyqxmd.com/read/28081314/cryptogenic-organizing-pneumonia-clinical-and-radiological-features-treatment-outcomes-of-17-patients-and-review-of-the-literature
#1
Elif Yelda Niksarlıoğlu, Gülcihan Zehra Özkan, Nur Dilek Bakan, Sibel Yurt, Lütfiye Kılıç, Güngör Çamsarı
BACKGROUND/AIM: We evaluated patients with cryptogenic organizing pneumonia (COP) who attended our clinic. MATERIALS AND METHODS: We retrospectively investigated the clinical and radiological findings, diagnostic methods, treatment, and follow-up outcomes of 17 patients who had been histopathologically diagnosed with COP. RESULTS: The mean age of the patients was 49.8 ± 10.4 years. The most common symptom was cough (n = 15; 88.2%) and the most common radiological finding (n = 10) was consolidation in the inferior lobes on thoracic computed tomography...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28066671/current-advances-of-endobronchial-ultrasonography-in-the-diagnosis-and-staging-of-lung-cancer
#2
REVIEW
Chao-Chi Ho, Ching-Kai Lin, Ching-Yao Yang, Lih-Yu Chang, Shu-Yung Lin, Chong-Jen Yu
The diagnosis and staging of patients with lung cancer has relied on tissue sampling. Endobronchial ultrasound (EBUS) is a minimally invasive procedure for the rapid and safe acquisition of tissue and can be done easily and repeatedly. EBUS transbronchial needle aspiration (TBNA) is now the standard for diagnosis of mediastinal and hilar lymphadenopathy and should be considered in patients who have a high probability of lymph node metastases without systemic involvement. EBUS also provides guidance for biopsy of peripheral lung lesions...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066590/comparison-of-radial-endobronchial-ultrasound-with-a-guide-sheath-and-with-distance-by-thin-bronchoscopy-for-the-diagnosis-of-peripheral-pulmonary-lesions-a-prospective-randomized-crossover-trial
#3
Su-Juan Zhang, Ming Zhang, Jun Zhou, Qiu-Di Zhang, Qian-Qian Xu, Xiong Xu
BACKGROUND: Transbronchial biopsy (TBB) using radial endobronchial ultrasound with a guide sheath (REBUS-GS) has improved the diagnosis of peripheral pulmonary lesions (PPLs). Because of the high cost of the GS, REBUS with distance (REBUS-D) has certain advantages. The aim of this study was to compare the diagnostic yield of the REBUS-GS and REBUS-D by thin bronchoscopy for PPLs. METHODS: Patients with PPLs were enrolled in a prospective randomized crossover study from August 2014 and July 2015...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28057436/comparison-of-clinically-relevant-mutation-profiles-between-preoperative-biopsy-and-corresponding-surgically-resected-specimens-in-japanese-patients-with-non-small-cell-lung-cancer-by-amplicon-based-massively-parallel-sequencing
#4
Mitsuhiro Isaka, Masakuni Serizawa, Hirotsugu Kenmotsu, Yasuhiro Koh, Shoji Takahashi, Tomohiro Maniwa, Kazushige Wakuda, Akira Ono, Tateaki Naito, Haruyasu Murakami, Keita Mori, Masahiro Endo, Masato Abe, Isamu Hayashi, Takashi Nakajima, Nobuyuki Yamamoto, Toshiaki Takahashi, Yasuhisa Ohde
BACKGROUND: Amplicon-based massively parallel sequencing (MPS) is an effective platform for identifying clinically actionable mutations across many genes in limited amounts of tissue. Most lung cancers are diagnosed and staged using small tissue samples obtained by transbronchial biopsy (TBB). To determine whether the mutations in TBB specimens detected by amplicon-based MPS reflect those present in the tumors, we compared the mutational profiles of preoperative TBB specimens and corresponding surgically resected specimens...
December 2, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28056871/lung-adenocarcinoma-expressing-receptor-for-advanced-glycation-end-products-with-primary-systemic-al-amyloidosis-a-case-report-and-literature-review
#5
Shouichi Okamoto, Shinsaku Togo, Ichiro Nagata, Kazue Shimizu, Yoshika Koinuma, Yukiko Namba, Jun Ito, Toshimasa Uekusa, Kazuhisa Takahashi
BACKGROUND: Receptor for advanced glycation end-products (RAGE), a receptor for amyloids, is constitutively expressed in lungs and generally observed to be downregulated in lung cancer tissues. However, increasing levels of RAGE or serum amyloids is associated with poor outcome in lung cancer patients. We report a rare case of primary systemic amyloid light-chain (AL) amyloidosis in biopsy-proven multiple organs with early-stage non-small cell lung cancer (NSCLC) that displayed strong staining for RAGE in the tumour tissue...
January 5, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28054531/diagnostic-value-of-core-biopsy-histology-and-cytology-sampling-of-mediastinal-lymph-nodes-using-21-gauge-ebus-tbna-needle
#6
Preyas J Vaidya, Avinandan Saha, Arvind H Kate, Kamlesh Pandey, Vinod B Chavhan, Joerg D Leuppi, Prashant N Chhajed
INTRODUCTION: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is the initial modality of choice in sampling mediastinal lymphadenopathy. It is possible to obtain both cytological and histological samples using both 21-gauge and 22-gauge EBUS-TBNA needles. The current study was undertaken to compare the diagnostic yield of cytology and histology samples obtained by the same EBUS-TBNA 21-gauge needle. PATIENTS AND METHODS: One hundred sixty-six consecutive patients who underwent EBUS-TBNA with a 21-gauge EBUS-TBNA needle over a period of 3 years were included in this retrospective analysis...
July 2016: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28052172/role-of-transbronchial-needle-aspiration-conventional-and-ebus-guided-in-the-diagnosis-of-histoplasmosis-in-patients-presenting-with-mediastinal-lymphadenopathy
#7
Amik Sodhi, Rodjawan Supakul, George W Williams, Elizabeth A Tolley, Arthur S Headley, Luis C Murillo, Dipen Kadaria
OBJECTIVES: The superior performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the diagnosis and staging of malignancy has been demonstrated, with some investigators suggesting the same for sarcoidosis. The role of EBUS-TBNA in the diagnosis of histoplasmosis is not clear, however. In this study we estimate the diagnostic yield of conventional TBNA (cTBNA) and EBUS-TBNA for the diagnosis of histoplasmosis in patients with mediastinal lymphadenopathy...
January 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28051017/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-increases-the-yield-of-transbronchial-lung-biopsy-for-the-evaluation-of-peribronchial-lesions
#8
Cheng Chen, Chuan-Yong Mu, Mei-Qin Su, Jing-Yu Mao, Ye-Han Zhu, Jian-An Huang
BACKGROUND: Due to absence of visible endobronchial target, the diagnostic yield of flexible bronchoscopy for peribronchial lesions has been unsatisfactory. Convex probe endobronchial ultrasound (CP-EBUS) has allowed for performing real-time transbronchial needle aspiration (TBNA) of enlarged hilar and mediastinal lymph nodes and therefore could also be used as a means of diagnosing proximal peribronchial lesions. METHODS: We retrospectively analyzed the results related to 72 patients who underwent CP-EBUS for peribronchial lesions without endobronchial involvement and adjacent to three-grade bronchi based on chest computed tomography (CT) scan...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28050417/diffuse-parenchymal-lung-diseases-with-clinicoradiological-discordance-role-of-transbronchial-lung-biopsy-as-a-diagnostic-tool-an-observational-study
#9
K P Suraj, Kiran Vishnu Narayan, Jyothi Edakalavan, Neethu Kesava Kumar
INTRODUCTION: The diagnosis of Diffuse Parenchymal Lung Disease (DPLD) requires a multidisciplinary approach with reconciliation of clinicoradiological and histopathological data. But when the preliminary clinicoradiological profile fails to suggest a diagnosis, an adequate lung biopsy specimen with meticulous histological examination and a multidisciplinary approach usually yields results. There is also a high chance of sampling error due to patchy and heterogeneous involvement of the disease process and due to the small volume of tissue taken...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28046957/su-g-bra-05-application-of-a-feature-based-tracking-algorithm-to-kv-x-ray-fluoroscopic-images-toward-marker-less-real-time-tumor-tracking
#10
M Nakamura, M Nakao, Y Matsuo, N Mukumoto, Y Iizuka, K Yokota, T Mizowaki, M Hiraoka
PURPOSE: To detect target position on kV X-ray fluoroscopic images using a feature-based tracking algorithm, Accelerated-KAZE (AKAZE), for markerless real-time tumor tracking (RTTT). METHODS: Twelve lung cancer patients treated with RTTT on the Vero4DRT (Mitsubishi Heavy Industries, Japan, and Brainlab AG, Feldkirchen, Germany) were enrolled in this study. Respiratory tumor movement was greater than 10 mm. Three to five fiducial markers were implanted around the lung tumor transbronchially for each patient...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040772/three-dimensional-virtual-bronchoscopy-using-a-tablet-computer-to-guide-real-time-transbronchial-needle-aspiration
#11
Alfonso Fiorelli, Antonio Raucci, Roberto Cascone, Alfonso Reginelli, Davide Di Natale, Carlo Santoriello, Antonio Capuozzo, Roberto Grassi, Nicola Serra, Mario Polverino, Mario Santini
OBJECTIVES: We proposed a new virtual bronchoscopy tool to improve the accuracy of traditional transbronchial needle aspiration for mediastinal staging. METHODS: Chest-computed tomographic images (1 mm thickness) were reconstructed with Osirix software to produce a virtual bronchoscopic simulation. The target adenopathy was identified by measuring its distance from the carina on multiplanar reconstruction images. The static images were uploaded in iMovie Software, which produced a virtual bronchoscopic movie from the images; the movie was then transferred to a tablet computer to provide real-time guidance during a biopsy...
December 31, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28031828/three-simultaneous-cases-of-hypersensitivity-pneumonitis-and-acute-lung-injury-caused-by-dichloromethane
#12
Kei Takamura, Takahiro Ogi, Makoto Yamamoto, Keisuke Kikuchi
Three middle-aged male patients were admitted to our hospital complaining of dry cough, dyspnoea, and fever. All three of them had cleaned a refrigerator at a Chinese noodle mill using paint remover containing dichloromethane (90%) the previous day. Chest X-rays revealed bilateral diffuse infiltrative shadows on the lungs. We performed transbronchial lung biopsies and bronchoalveolar lavage (BAL) via bronchoscopy for each patient. Bronchoalveolar lavage showed increased total cell count as well as lymphocyte and neutrophil fraction...
November 2016: Respirology Case Reports
https://www.readbyqxmd.com/read/28027732/endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-the-nodal-staging-of-stereotactic-ablative-body%C3%A2-radiotherapy-patients
#13
Macarena R Vial, Kashif A Khan, Oisin O'Connell, S Andrew Peng, Daniel R Gomez, Joe Y Chang, David C Rice, Reza Mehran, Carlos J Jimenez, Horiana B Grosu, David E Ost, George A Eapen
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) being evaluated for stereotactic ablative body radiotherapy (SABR) are typically staged noninvasively with positron emission tomography/computed tomography (PET/CT). Incorporating endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) into the staging workup of these patients has not been evaluated. Our primary objective was to compare the performance of PET/CT with EBUS-TBNA for intrathoracic nodal assessment among SABR-eligible patients...
December 24, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28005836/pulmonologist-performed-per-esophageal-needle-aspiration-of-parenchymal-lung-lesions-using-an-ebus-bronchoscope-diagnostic-utility-and-safety
#14
Daniel P Steinfort, Michael W Farmer, Louis B Irving, Barton R Jennings
BACKGROUND: Transesophageal introduction of the endobronchial ultrasound (EBUS) videobronchoscope allows pulmonologists to perform endoscopic ultrasound fine-needle aspiration (EUS-B-FNA) of mediastinal lesions. Safety, diagnostic accuracy, and feasibility of EUS-B-FNA in evaluation of pulmonary parenchymal lesions are not established. METHODS: All patients undergoing pulmonologist-performed EUS-B-FNA of parenchymal lung lesions at 2 tertiary centers were included in this prospective observational cohort study...
December 21, 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28005832/going-off-road-the-first-case-reports-of-the-use-of-the-transbronchial-access-tool-with-electromagnetic-navigational-bronchoscopy
#15
Carlos Anciano, Craig Brown, Mark Bowling
The ability to reach the peripheral pulmonary nodule/mass with bronchoscopy has improved greatly over the past several years with the use of Electromagnetic navigational bronchoscopy; however, many of these lesions are unable to be adequately sampled due to their location outside the bronchial airways. We report the first use of the transbronchial access tool that creates a pathway from the bronchial airway through the lung parenchyma into the targeted lung abnormality.
December 21, 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27984385/conventional-transbronchial-needle-aspiration-versus-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-with-or-without-rapid-on-site-evaluation-for-the-diagnosis-of-sarcoidosis-a-randomized-controlled-trial
#16
Karan Madan, Ashesh Dhungana, Anant Mohan, Vijay Hadda, Deepali Jain, Sudheer Arava, Ravindra M Pandey, Gopi C Khilnani, Randeep Guleria
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) as a standalone modality is superior to conventional TBNA (c-TBNA) for the diagnosis of sarcoidosis. However, the overall yield is not different if combined with endobronchial biopsy (EBB) and transbronchial lung biopsy (TBLB). The utility of rapid on-site evaluation (ROSE) in a comparative evaluation of EBUS-TBNA versus c-TBNA for the diagnosis of sarcoidosis has not been previously evaluated. METHODS: Eighty patients with suspected sarcoidosis were randomized 1:1:1:1 into 4 groups: c-TBNA without ROSE (TBNA-NR), c-TBNA with ROSE (TBNA-R), EBUS-TBNA without ROSE (EBUS-NR), and EBUS-TBNA with ROSE (EBUS-R)...
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27984382/diagnostic-yield-and-complications-of-ebus-tbna-performed-under-bronchoscopist-directed-conscious-sedation-single-center-experience-of-1004-subjects
#17
Sahajal Dhooria, Inderpaul S Sehgal, Nalini Gupta, Ashutosh N Aggarwal, Digambar Behera, Ritesh Agarwal
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can be performed under either conscious sedation or general anesthesia. Herein, we describe the diagnostic yield and complications of EBUS-TBNA performed under bronchoscopist-directed conscious sedation. METHODS: This is a retrospective analysis of data collected in the bronchoscopy suite of this center on EBUS-TBNA or endoscopic ultrasound with a bronchoscope-guided fine needle aspiration (EUS-B-FNA) procedures performed between July 2011 and January 2016...
January 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27980084/utility-of-rapid-on-site-cytologic-evaluation-during-endobronchial-ultrasound-with-a-guide-sheath-for-peripheral-pulmonary-lesions
#18
Takehiro Izumo, Yuji Matsumoto, Shinji Sasada, Christine Chavez, Toshiyuki Nakai, Takaaki Tsuchida
OBJECTIVE: The utility of rapid on-site evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions is unclear. The aim of this study was to evaluate the role of rapid on-site evaluation during endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions. METHODS: Consecutive patients who underwent endobronchial ultrasound with a guide sheath for the diagnosis of peripheral pulmonary lesions at our hospital between September 2012 and July 2014 were included in this retrospective study...
December 15, 2016: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27977603/diagnostic-performance-of-convex-probe-ebus-tbna-in-patients-with-mediastinal-and-coexistent-endobronchial-or-peripheral-lesions
#19
Akash Verma, Kee San Goh, Chee Kiang Phua, Wen Yuan Sim, Kuan Sen Tee, Albert Y H Lim, Dessmon Y H Tai, Soon Keng Goh, Ai Ching Kor, Benjamin Ho, Sennen J W Lew, John Abisheganaden
To compare the performance of convex probe endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) with conventional endobronchial biopsy (EBB) or transbronchial lung biopsy (TBLB) in patients with mediastinal, and coexisting endobronchial or peripheral lesions.Retrospective review of records of patients undergoing diagnostic EBUS-TBNA and conventional bronchoscopy in 2014.A total of 74 patients had mediastinal, and coexisting endobronchial or peripheral lesions. The detection rate of EBUS-TBNA for mediastinal lesion >1 cm in short axis, EBB for visible exophytic type of endobronchial lesion, and TBLB for peripheral lesion with bronchus sign were 71%, 75%, and 86%, respectively...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27969481/ps01-14-diagnostic-yield-in-patients-undergoing-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-a%C3%A2-single-center-experience-topic-pulmonology
#20
Sunkaru Touray, Rahul N Sood, Carlos Martinez-Balzano, Jonathan Holdorf, Paulo J Oliveira, Scott E Kopec
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Oncology
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