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https://www.readbyqxmd.com/read/29330908/defining-expanded-areas-in-ebus-sampling-ebus-guided-trans-and-intra-pulmonary-artery-needle-aspiration-with-review-of-transvascular-ebus
#1
Ravindra M Mehta, Pavankumar R Biraris, Vallandramam Pattabhiraman, Arjun Srinivasan, Abhinav Singla, Sunil Kumar, Michael Cutaia
BACKGROUND: Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) has revolutionized the diagnostic approach to mediastinal diseases. Lesions located lateral to the pulmonary artery (trans-PA, Station 5), or in the lumen of the PA (intra-PA) are in the 'blind-spot' of EBUS. OBJECTIVES: We describe a case series where EBUS guided trans-pulmonary or intra-pulmonary aspiration (EBUS-TIPNA) was used for diagnosis. METHODS: Retrospective analysis of 10 patients who had EBUS-TIPNA over 3 years in 2 centers...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29321928/lung-cancer-development-in-the-patient-with-granulomatosis-with-polyangiitis-during-long-term-treatment-with-cyclophosphamide-first-documented-case
#2
Midori Toriyama, Etsuko Tagaya, Tomoko Yamamoto, Mitsuko Kondo, Yoji Nagashima, Jun Tamaoki
A 65-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) at the age of 47, when cytoplasmic anti-neutrophil cytoplasmic antibody (C-ANCA) serology was positive, and he had multiple nodular shadows in both lungs. He had been treated with prednisolone, cyclophosphamide (CPA) and plasma exchange. At the age of 64, a nodular shadow was newly detected in the right lower lung field and serum tumour marker increased. Subsequent positron emission tomography/computed tomography scan demonstrated accumulations of fluorodexyglucose (FDG) in the same area, mediastinum lymph nodes, thoracic wall, right iliac bone, and right retroperitoneum...
February 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29321926/lung-injury-associated-with-electronic-cigarettes-inhalation-diagnosed-by-transbronchial-lung-biopsy
#3
Masayuki Itoh, Kazutetsu Aoshiba, Yoriko Herai, Hiroyuki Nakamura, Tamiko Takemura
A 46-year-old healthy man developed respiratory distress, night sweats, fever, and weight loss after using electronic cigarettes (e-cigs) for approximately 1 month. He presented to the hospital when the symptoms worsened 2 months after onset. The findings of bronchoalveolar lavage (BAL) fluid examination and the following transbronchial lung biopsy examination led to the diagnosis of acute alveolitis: intra-alveolar fibrosis accompanied with exudate containing abundant lipid-laden macrophages, eosinophils, and neutrophils...
January 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29320774/how-many-passes-are-needed-for-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-for-sarcoidosis-a-prospective-multicenter-study
#4
Masahide Oki, Hideo Saka, Masahiko Ando, Harunori Nakashima, Akira Shiraki, Yasushi Murakami, Yoshihito Kogure, Chiyoe Kitagawa, Tatsuo Kato
BACKGROUND: While endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is widely used as an initial diagnostic procedure for pathological confirmation of sarcoidosis, it is unclear how many passes are required to obtain diagnostic materials. OBJECTIVES: The aim of this study was to determine the number of needle passes needed for the diagnosis of stage I/II sarcoidosis using EBUS-TBNA. METHODS: At three institutions, 109 patients with suspected stage I/II sarcoidosis were recruited and underwent 6 passes of EBUS-TBNA for the main target lesion...
January 10, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29316560/transbronchial-cryobiopsies-for-the-diagnosis-of-diffuse-parenchymal-lung-diseases-expert-statement-from-the-cryobiopsy-working-group-on-safety-and-utility-and-a-call-for-standardization-of-the-procedure
#5
Jürgen Hetzel, Fabien Maldonado, Claudia Ravaglia, Athol U Wells, Thomas V Colby, Sara Tomassetti, Jay H Ryu, Oren Fruchter, Sara Piciucchi, Alessandra Dubini, Alberto Cavazza, Marco Chilosi, Nicola Sverzellati, Dominique Valeyre, Dimitri Leduc, Simon L F Walsh, Stefano Gasparini, Martin Hetzel, Lars Hagmeyer, Maik Haentschel, Ralf Eberhardt, Kaid Darwiche, Lonny B Yarmus, Alfonso Torrego, Ganesh Krishna, Pallav L Shah, Jouke T Annema, Felix J F Herth, Venerino Poletti
Transbronchial cryobiopsies (TBCB) have recently been introduced as a promising and safer alternative to surgical lung biopsy in the diagnostic approach to diffuse parenchymal lung diseases (DPLD). Despite a substantial and expanding body of literature, the technique has not yet been standardized and its place in the diagnostic algorithm of DPLD remains to be defined. In part, this reflects concerns over the diagnostic yield and safety of the procedure, together with the rapid spread of the technique without competency and safety standards; furthermore, there is a substantial procedural variability among centers and interventional pulmonologists...
January 9, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29312759/virtual-fluoroscopy-during-transbronchial-biopsy-for-locating-ground-glass-nodules-not-visible-on-x-ray-fluoroscopy
#6
Toshiyuki Nakai, Takehiro Izumo, Yuji Matsumoto, Takaaki Tsuchida
Background: Virtual fluoroscopy (VF) is a novel guided technique that provides ray summation images of target lesions similar to X-ray fluoroscopy. Endobronchial ultrasound with a guide sheath (EBUS-GS) is a useful modality for imaging ground-glass nodules (GGNs) but is not ideal for GGNs that cannot be detected on X-ray fluoroscopy. We evaluated whether the addition of VF to EBUS-GS improved the diagnostic yield. Methods: Consecutive patients who had undergone diagnostic bronchoscopy for GGNs that were not detected on X-ray fluoroscopy between September 2012 and January 2016 were retrospectively enrolled...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312755/acute-rejection
#7
REVIEW
Mark Benzimra, Greg L Calligaro, Allan R Glanville
Despite induction immunosuppression and the use of aggressive maintenance immunosuppressive regimens, acute allograft rejection following lung transplantation is still a problem with important diagnostic and therapeutic challenges. As well as causing early graft loss and mortality, acute rejection also initiates the chronic alloimmune responses and airway-centred inflammation that predispose to bronchiolitis obliterans syndrome (BOS), also known as chronic lung allograft dysfunction (CLAD), which is a major source of morbidity and mortality after lung transplantation...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29306252/the-diagnostic-accuracy-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-ebus-tbna-in-mediastinal-tuberculous-lymphadenitis
#8
Onur Fevzi Erer, Serhat Erol, Ceyda Anar, Can Biçmen, Zekiye Aydoğdu, Serir Aktoğu
Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated mediastinal tuberculous lymphadenitis (MTLA). Materials and methods: This study included 527 patients who had undergone EBUS-TBNA between December 2012 and December 2014...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29299871/coronary-air-embolism-following-transbronchial-lung-biopsy
#9
Takuya Sumi, Akihito Tanaka, Hideki Ishii, Susumu Suzuki, Kenji Kada, Toyoaki Murohara
No abstract text is available yet for this article.
January 3, 2018: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/29290199/lung-cancer-with-concomitant-double-gene-mutation
#10
Tao Fan, Xiu-Li Liu, Jun Zhou, Ying-Jie Song, Hong Yang, Ya-Nan Wei
A patient presenting with concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocation is very rare. We report a non-small cell lung cancer (NSCLC) patient with concomitant EGFR (exon 19-del) mutation and ALK rearrangement. The positron emission tomography-computed tomography (PET-CT) scan revealed a highly metabolic mass lesion in the left lower lobe, measured 5.0 cm in the largest dimension in the S6 segment. Transbronchial lung biopsy (TBLB) showed the pathological diagnosis of invasive adenocarcinoma...
January 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29277564/feasibility-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-cytology-specimens-for-next-generation-sequencing-in-non-small-cell-lung-cancer
#11
Sean P Stoy, Jeremy P Segal, Jeffrey Mueller, Larissa V Furtado, Everett E Vokes, Jyoti D Patel, Septimiu Murgu
INTRODUCTION: Next generation sequencing (NGS) testing of lung cancer is recommended by guidelines, and endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) often provides the only material available for testing. Previous studies have demonstrated successful NGS testing on cell block samples obtained by EBUS; however, cytology smears provide a more reliable sample with better DNA quality for testing. In this study, we aimed to determine the success rate of OncoScreen (50 gene) and OncoPlus (1213 gene) panel NGS testing of cytology samples obtained by EBUS utilizing 22- and 25-gauge needles...
December 5, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/29276675/an-onion-farmer-with-a-case-of-hypersensitivity-pneumonitis-caused-by-aspergillus-niger
#12
Tomohiro Sakamoto, Akira Yamasaki, Yoshihiro Funaki, Tomoya Harada, Ryota Okazaki, Yasuyuki Hasegawa, Yuriko Sueda, Takehito Fukushima, Masahito Morita, Akihiro Yamamoto, Masahiro Kodani, Eiji Shimizu
A 62-year old man was admitted to our hospital with a 2-week complaint of a dry cough, general fatigue, and dyspnea on effort. He has been an onion farmer for several years and developed these symptoms after cleaning up onion peels with air compressors. A chest roentgenogram and computed tomography showed a ground glass shadow in the bilateral upper lung field. Cellular analysis of the bronchoalveolar lavage fluid showed elevated total cell numbers and lymphocytes. Transbronchial lung biopsies revealed a non-caseating granuloma with both epithelioid cells and Langhans giant cells...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29276672/combined-pleuroscopy-and-endobronchial-ultrasound-for-diagnosis-and-staging-of-suspected-lung-cancer
#13
Macarena R Vial, George A Eapen, Roberto F Casal, Mona G Sarkiss, David E Ost, Erik Vakil, Horiana B Grosu
The standard approach to staging of lung cancer in patients with pleural effusion (clinical M1a) is thoracentesis followed by pleural biopsies if the cytologic analysis is negative. If pleural biopsy findings are negative, endobronchial ultrasound-guided transbronchial needle aspiration is used to complete the staging process and, in some cases, obtain diagnosis. In this case series we report 7 patients in which a combined procedure was performed for staging of known or suspected lung cancer. We found that the combined approach was both feasible and safe in this case series...
2018: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29275603/-efficacy-and-safety-of-transbronchial-cryobiopsy-in-the-etiologic-diagnosis-of-diffuse-lung-disease
#14
Y S Li, S L Guo, X H Yi, M L Xiao, X X Jin, Y Xiao, X Y Zhu, X Li, L W Dai, Z Ao, X Z Liu, M Ding
Objective: To assess the efficacy and safety of transbronchial cryobiopsy (TBCB) for the etiologic evaluation of diffuse lung disease (DLD). Methods: Between December 2015 to April 2017, a total of 38 patients with DLD met the inclusion criteria for TBCB in the First Affiliated Hospital of Chongqing Medical University, and 35 of them consented to undergo the procedure under rigid or flexible bronchoscopy. On the tissues obtained from the 35 patients, histopathologic and microbiological evaluations were performed, and together with clinical and radiological manifestations, diagnoses were made and the efficacy of TBCB in the diagnosis of DLD was confirmed, and then therapies were planned accordingly...
December 12, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29261589/transbronchial-lung-cryobiopsy-with-2-bronchoscopes-nec-novum-nec-magna
#15
Sahajal Dhooria, Inderpaul S Sehgal, Kuruswamy T Prasad, Ritesh Agarwal
No abstract text is available yet for this article.
January 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29261582/efficacy-of-endobronchial-ultrasound-transbronchial-needle-aspiration-virtual-reality-simulator-training
#16
Lars Konge, Paul F Clementsen, Jouke Annema
No abstract text is available yet for this article.
January 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29261581/risk-of-jaw-dislocation-with-prolonged-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#17
Usman Maqsood, Janet Mills, Mohammed Munavvar
No abstract text is available yet for this article.
January 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/29248880/constrictive-bronchiolitis-presenting-with-a-mixed-obstructive-and-restrictive-pattern-associated-with-acid-reflux
#18
Kristen Capel, Richard Dee Shih
A previously healthy 55-year-old woman presented with worsening dyspnoea on exertion. The patient lived at altitude, did not smoke and had no exposure to occupational or environmental toxins. Her physical examination, including pulmonary, was unremarkable. Pulmonary function tests showed forced expiratory volume in 1 s/forced vital capacity ratio 74% predicted, diffusing capacity for carbon monoxide (DLCO) 92% predicted and residual volume 213% predicted. Rheumatological workup was negative. Chest radiograph showed hyperinflation without consolidation, and high-resolution chest CT showed mosaic attenuation with air trapping on expiratory imaging...
December 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29242258/ers-statement-interventional-bronchoscopy-in-children
#19
Ernst Eber, Juan L Antón-Pacheco, Jacques de Blic, Iolo Doull, Al Faro, Raffaella Nenna, Thomas Nicolai, Petr Pohunek, Kostas N Priftis, Paola Serio, Courtney Coleman, Sarah Masefield, Thomy Tonia, Fabio Midulla
Paediatric airway endoscopy is accepted as a diagnostic and therapeutic procedure, with an expanding number of indications and applications in children. The aim of this European Respiratory Society task force was to produce a statement on interventional bronchoscopy in children, describing the evidence available at present and current clinical practice, and identifying areas deserving further investigation. The multidisciplinary task force panel performed a systematic review of the literature, focusing on whole lung lavage, transbronchial and endobronchial biopsy, transbronchial needle aspiration with endobronchial ultrasound, foreign body extraction, balloon dilation and occlusion, laser-assisted procedures, usage of airway stents, microdebriders, cryotherapy, endoscopic intubation, application of drugs and other liquids, and caregiver perspectives...
December 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29228929/virtual-bronchoscopic-navigation-without-x-ray-fluoroscopy-to-diagnose-peripheral-pulmonary-lesions-a-randomized-trial
#20
Fumihiro Asano, Takashi Ishida, Naofumi Shinagawa, Noriaki Sukoh, Masaki Anzai, Kenya Kanazawa, Akifumi Tsuzuku, Satoshi Morita
BACKGROUND: Transbronchial biopsy for peripheral pulmonary lesions is generally performed under X-ray fluoroscopy. Virtual bronchoscopic navigation (VBN) is a method in which virtual images of the bronchial route to the lesion are produced based on CT images obtained before VBN, and the bronchoscope is guided using these virtual images, improving the diagnostic yield of peripheral pulmonary lesions. VBN has the possibility of eliminating the need for X-ray fluoroscopy in the bronchoscopic diagnosis of peripheral lesions...
December 11, 2017: BMC Pulmonary Medicine
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