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https://www.readbyqxmd.com/read/29154685/a-qualitative-analysis-of-real-time-continuous-glucose-monitoring-data-sharing-with-care-partners-to-share-or-not-to-share
#1
Michelle L Litchman, Nancy A Allen, Vanessa D Colicchio, Sarah E Wawrzynski, Kerri M Sparling, Krissa L Hendricks, Cynthia A Berg
BACKGROUND: Little research exists regarding how real-time continuous glucose monitoring (RT-CGM) data sharing plays a role in the relationship between patients and their care partners. OBJECTIVE: To (1) identify the benefits and challenges related to RT-CGM data sharing from the patient and care partner perspective and (2) to explore the number and type of individuals who share and follow RT-CGM data. METHODS: This qualitative content analysis was conducted by examining publicly available blogs focused on RT-CGM and data sharing...
November 20, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29151531/repeated-hypoglycemic-episodes-with-postprandial-hyperinsulinemia-after-the-recovery-from-acute-weight-loss-revealed-by-continuous-glucose-monitoring-and-the-oral-glucose-tolerance-test
#2
Seizaburo Masuda, Masanori Murakami, Ryotaro Bouchi, Isao Minami, Koshi Hashimoto, Takanobu Yoshimoto, Yoshihiro Ogawa
We herein report a case of a 20-year-old woman who experienced hypoglycemia in parallel with acute weight loss confirmed by continuous glucose motoring (CGM). When she recovered from the acute weight loss, CGM revealed nocturnal and postprandial hypoglycemia. Six months were required to resolve the hypoglycemia and hyperinsulinemia after the recovery of her weight. Our case suggests that the adaption of insulin secretion to the rapid loss of weight and to the recovery of weight may require a long period of time, leading to the excessive secretion of insulin relative to the glucose level and repeated hypoglycemic episodes with postprandial hyperinsulinemia...
November 20, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29148821/the-effect-of-prior-continuous-glucose-monitoring-use-on-glycemic-outcomes-in-the-pivotal-trial-of-the-minimed-%C3%A2-670g-hybrid-closed-loop-system
#3
Toni L Cordero, Satish K Garg, Ronald Brazg, Timothy S Bailey, John Shin, Scott W Lee, Francine R Kaufman
A 3-month pivotal trial using the MiniMed™ 670G hybrid closed-loop (HCL) system in adolescent and adult patients with type 1 diabetes (T1D), relative to a 2-week baseline run-in period, resulted in increased sensor glucose (SG) values in target range (71-180 mg/dL), reduced HbA1c levels, and no events of diabetic ketoacidosis or severe hypoglycemia ( Clinicaltrials.gov : NCT02463097). This brief report evaluated how prior continuous glucose monitoring (CGM) experience influenced glycemic outcomes, in the same pivotal trial...
November 17, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29144814/self-blood-glucose-monitoring-underestimates-hyperglycemia-and-hypoglycemia-as-compared-to-continuous-glucose-monitoring-in-type-1-and-type-2-diabetes
#4
Devna Mangrola, Christine Cox, Arianne S Furman, Sridevi Krishnan, Sidika E Karakas
OBJECTIVE: When glucose records from self-blood glucose monitoring (SBGM) do not reflect estimated average glucose from HgBA1, or when patients' clinical symptoms are not explained by their SBGM records, clinical management of diabetes becomes a challenge. Our objective was to determine the magnitude of differences in glucose values reported by SBGM vs. documented by continuous glucose monitoring (CGM). METHODS: The CGM was conducted by a clinical diabetes educator/registered nurse by the clinic protocol, using the Medtronic iPRO2™ system...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29139589/severe-fasting-hypoglycemia-in-a-child-after-total-pancreatectomy-with-islet-autotransplantation
#5
Jacob M Redel, Jaimie D Nathan, Maisam Abu-El-Haija, Tom K Lin, Joseph J Palermo, Deborah A Elder
TPIAT is an increasingly utilized treatment option for select children with CP. Post-TPIAT fasting hypoglycemia, unrelated to exogenous insulin, is a complication recently reported in adults. This phenomenon has not been described in children. We review a case of severe fasting hypoglycemia in an adolescent female occurring 10 months post-TPIAT. A 12-year-old girl underwent TPIAT for CP. Ten months postoperatively she developed recurrent hypoglycemia on a total daily insulin dose of 0.03 units/kg. Consequently, insulin therapy was discontinued...
November 15, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29137964/oral-glucose-tolerance-test-and-continuous-glucose-monitoring-to-assess-diabetes-development-in-cystic-fibrosis-patients
#6
María Clemente León, Laura Bilbao Gassó, Antonio Moreno-Galdó, Ariadna Campos Martorrell, Silvia Gartner Tizzano, Diego Yeste Fernández, Antonio Carrascosa Lezcano
INTRODUCTION: Patients with cystic fibrosis (CF) undergo a slow and progressive process toward diabetes. Oral glucose tolerance test (OGTT) is recommended to diagnose impaired glucose levels in these patients. Continuous glucose monitoring (CGM) measures glucose profiles under real-life conditions. OBJECTIVE: To compare OGTT and CGM results in CF patients. METHODS: Paired OGTT and 6-day CGM profiles (146.2±9.1h/patient) were performed in 30 CF patients aged 10-18 years...
November 11, 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29120781/balsamic-type-varietal-vinegar-from-cv-xinomavro-northen-greece-optimization-and-scale-up-of-the-alcoholic-fermentation-step-using-indigenous-multistarters
#7
Sofia Lalou, Maria Ferentidou, Fani Th Mantzouridou, Maria Z Tsimidou
Taguchi design was used to examine the effect of parameters that should be optimized in order to control the alcoholic fermentation of the concentrated grape must (CGM) from cv. Xinomavro using the best-performing indigenous Hanseniaspora uvarum and Saccharomyces cerevisiae strains as multistarters. The "optimum" combination of conditions (cell ratio of H. uvarum/S. cerevisiae; inoculum size and inoculation time of S. cerevisiae; fermentation time and temperature) resulted in an alcoholic product that meets ethanol (79 g/kg) and residual sugar (164 g/kg) content requirements for further use in the production of balsamic type vinegar...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29118986/sensor-augmented-csii-therapy-with-predictive-low-glucose-suspend-following-total-pancreatectomy
#8
E S Scott, G R Fulcher, R J Clifton-Bligh
Pancreatogenic diabetes is characterised by recurrent severe hypoglycaemia due to changes in both endocrine and exocrine functions. There are no guidelines to manage these individuals. Herein, we describe the post-operative management of two people who developed pancreatogenic diabetes following total pancreatectomy for neuroendocrine malignancy. In both individuals, diabetes was managed using sensor-augmented predictive low-glucose suspend continuous subcutaneous insulin infusion (CSII). We demonstrate the benefit of sensor-augmented CSII in averting hypoglycaemia whilst optimising glycaemic control...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29107758/exploring-correlates-of-diabetes-related-stress-among-adults-with-type-1-diabetes-in-the-t1d-exchange-clinic-registry
#9
Matthew Tyler Boden, Sasha Gala
AIMS: To explore relations between diabetes-related stress and multiple sociodemographic, diabetes health, other health, and treatment-related variables among a large, diverse sample of adults with Type 1 Diabetes (T1D). METHODS: The sample consisted of 10,821 adults (over 18 years old) enrolled in the T1D Exchange Clinic Registry. The T1D Exchange clinic network consists of 67 diabetes clinical centers throughout the United States selected to broadly represent pediatric and adult patients with T1D...
October 28, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29103302/continuous-glucose-monitoring-measures-can-be-used-for-glycemic-control-in-the-icu-an-in-silico-study
#10
Tony Zhou, Jennifer L Dickson, Geoffrey M Shaw, J Geoffrey Chase
BACKGROUND: Continuous glucose monitoring (CGM) technology has become more prevalent in the intensive care unit (ICU), offering potential benefits of increased safety and reduced workload in glycemic control (GC). The drift and higher point accuracy errors of CGM devices over traditional intermittent blood glucose (BG) measures have so far limited their application in the ICU. This study delineates the trade-offs of performance, safety and workload that CGM sensors provide in GC protocols...
November 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29077488/perspectives-on-long-distance-air-travel-with-type-1-diabetes
#11
Jordan E Pinsker, Benjamen E Schoenberg, Colleen Garey, Asher Runion, Arianna Larez, David Kerr
We sought to determine the real-life experiences of individuals traveling long distance (across five or more time-zones) with type 1 diabetes (T1D). Five hundred three members of the T1D Exchange online community ( www.myglu.org ) completed a 45-question survey about their travel experiences flying long distance. The cohort was stratified by duration of T1D and whether or not participants used continuous subcutaneous insulin infusion (CSII) therapy and/or a continuous glucose monitor (CGM). In the last 5 years, 71% of participants had flown long distance...
October 27, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29077235/strontium-carbonate-precipitation-as-a-sample-preparation-technique-for-isotope-ratio-analysis-of-sr-in-mineral-water-and-wine-by-quadrupole-based-icp-ms
#12
M Dronov, T Koza, A Schwiers, T C Schmidt, J Schram
RATIONALE: The defined origin of food products is nowadays often seen as a marker of quality. Sr isotope ratio determination can be used to verify the origin of such food products and it has thus become an important technique. Wine samples in particular are often investigated using this technique. Sr isotopic ratio measurements are often disturbed by isobaric Rb interference, making a separation procedure necessary. In this investigation a very simple and effective procedure for the separation of Rb(+) and Sr(2+) ions for Sr isotope ratio determination in mineral water and wine samples was developed...
October 27, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29076353/manufacturing-process-changes-and-reduced-skin-irritations-of-an-adhesive-patch-used-for-continuous-glucose-monitoring-devices
#13
Vitaliy Gisin, Anna Chan, John B Welsh
Adhesives used for continuous glucose monitoring (CGM) devices can cause skin irritations, which sometimes lead to abandonment of the therapy. A previous sensor manufacturing process involved two separate adhesives-one applied to the skin-facing surface of the fabric patch, and a second, ethyl cyanoacrylate-based adhesive, which secured the plastic transmitter housing to the superficial side of the patch. Our current process for attaching the transmitter housing to the fabric patch uses heatstaking, wherein the housing is heated and pressed against the patch with a specialized assembly apparatus...
October 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29070577/improving-the-clinical-value-and-utility-of-cgm-systems-issues-and-recommendations-a-joint-statement-of-the-european-association-for-the-study-of-diabetes-and-the-american-diabetes-association-diabetes-technology-working-group
#14
REVIEW
John R Petrie, Anne L Peters, Richard M Bergenstal, Reinhard W Holl, G Alexander Fleming, Lutz Heinemann
The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionize the use of intensive insulin therapy in diabetes; however, progress toward that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardized format for displaying results, and uncertainty on how best to use CGM data to make therapeutic decisions...
October 25, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29067486/improving-the-clinical-value-and-utility-of-cgm-systems-issues-and-recommendations-a-joint-statement-of-the-european-association-for-the-study-of-diabetes-and-the-american-diabetes-association-diabetes-technology-working-group
#15
REVIEW
John R Petrie, Anne L Peters, Richard M Bergenstal, Reinhard W Holl, G Alexander Fleming, Lutz Heinemann
The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionise the use of intensive insulin therapy in diabetes; however, progress towards that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardised format for displaying results and uncertainty on how best to use CGM data to make therapeutic decisions...
December 2017: Diabetologia
https://www.readbyqxmd.com/read/29063509/erratum-to-efficacy-of-additional-canagliflozin-administration-to-type-2-diabetes-patients-receiving-insulin-therapy-examination-of-diurnal-glycemic-patterns-using-continuous-glucose-monitoring-cgm
#16
Mihoko Matsumura, Yuki Nakatani, Seiichi Tanka, Chie Aoki, Masaaki Sagara, Kazunori Yanagi, Kunihiro Suzuki, Yoshimasa Aso
Unfortunately, the original publication of this paper contained errors in the presentation of Fig. 2.
October 23, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29061323/comparison-of-continuous-glucose-monitoring-in-adolescents-with-type-1-diabetes-ramadan-versus-non-ramadan
#17
Walid Kaplan, Bachar Afandi, Noura Al Hassani, Suha Hadi, Taoufik Zoubeidi
AIM: To assess the impact of fasting on interstitial glucose (IG) in adolescents with type 1 DM (T1DM) by using continuous glucose monitoring (CGM). METHOD: A minimum of 2.5 days CGM was done on adolescents with T1DM during fasting in Ramadan and in the month before or after Ramadan to compare the differences in mean IG, and in the durations of hypoglycemia (<70 mg/dL), hyperglycemia (200-299 mg/dL), and severe hyperglycemia (≥300 mg/dL). RESULTS: Fourteen adolescents were studied, age 15 ± 4 years, duration of diabetes 6 ± 4 years, and HbA1C 8...
October 20, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29060503/a-deep-learning-approach-to-adherence-detection-for-type-2-diabetics
#18
Ali Mohebbi, Tinna B Aradottir, Alexander R Johansen, Henrik Bengtsson, Marco Fraccaro, Morten Morup
Diabetes has become one of the biggest health problems in the world. In this context, adherence to insulin treatment is essential in order to avoid life-threatening complications. In this pilot study, a novel adherence detection algorithm using Deep Learning (DL) approaches was developed for type 2 diabetes (T2D) patients, based on simulated Continuous Glucose Monitoring (CGM) signals. A large and diverse amount of CGM signals were simulated for T2D patients using a T2D adapted version of the Medtronic Virtual Patient (MVP) model for T1D...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060208/data-driven-strategies-for-robust-forecast-of-continuous-glucose-monitoring-time-series
#19
Samuele Fiorini, Chiara Martini, Davide Malpassi, Renzo Cordera, Davide Maggi, Alessandro Verri, Annalisa Barla
Over the past decade, continuous glucose monitoring (CGM) has proven to be a very resourceful tool for diabetes management. To date, CGM devices are employed for both retrospective and online applications. Their use allows to better describe the patients' pathology as well as to achieve a better control of patients' level of glycemia. The analysis of CGM sensor data makes possible to observe a wide range of metrics, such as the glycemic variability during the day or the amount of time spent below or above certain glycemic thresholds...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060152/personalization-of-a-compartmental-physiological-model-for-an-artificial-pancreas-through-integration-of-patient-s-state-estimation
#20
P Jallon, S Lachal, C Franco, G Charpentier, E Huneker, M Doron, Sylvia Franc, Pierre-Yves Benhamou, Sophie Borot, Bruno Guerci, He le Ne Hanaire, Nathalie Jeandidier, Alfred Penfornis, Eric Renard, Yves Reznik, Pauline Schaepelynck, Chantal Simon
Artificial Pancreas (AP) are developed for patients with Type 1 diabetes. This medical device system consists in the association of a subcutaneous continuous glucose monitor (CGM) providing a proxy of the patient's glycaemia and a control algorithm offering the real-time modification of the insulin delivery with an automatic command of the subcutaneous insulin pump. The most complex algorithms are based on a compartmental model of the glucoregulatory system of the patient coupled to an approach of MPC (Model-Predictive-Control) for the command...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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