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https://www.readbyqxmd.com/read/29773460/cpap-therapy-improves-erectile-function-in-patients-with-severe-obstructive-sleep-apnea
#1
Richard Schulz, Fabian Bischoff, Wolfgang Galetke, Henning Gall, Jörg Heitmann, Andrea Hetzenecker, Markus Laudenburg, Till Jonas Magnus, Georg Nilius, Christina Priegnitz, Winfried Randerath, Maik Schröder, Marcel Treml, Michael Arzt
OBJECTIVES: Erectile dysfunction (ED) is highly prevalent in obstructive sleep apnea (OSA), however, the effect of continuous positive airway pressure (CPAP) therapy on erectile function has not yet been thoroughly investigated in these patients. METHODS: Ninety-four men with severe OSA (ie, with an apnea-hypopnea-index ≥ 30/h of sleep) were prospectively evaluated for the presence and severity of ED before and after 6-12 months of CPAP therapy. The abbreviated version of the International Index of Erectile Function, (the IIEF-5) was used to rate erectile function...
April 10, 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29734988/change-in-cognition-and-other-non-motor-symptoms-with-obstructive-sleep-apnea-treatment-in-parkinson-disease
#2
Marta Kaminska, Victoria P Mery, Anne-Louise Lafontaine, Ann Robinson, Andrea Benedetti, Priti Gros, R John Kimoff
STUDY OBJECTIVES: Parkinson disease (PD) non-motor symptoms are associated with sleep disorders and impair quality of life. Our objective was to assess the effect of obstructive sleep apnea (OSA) treatment using continuous positive airway pressure (CPAP) on PD non-motor symptoms. METHODS: In this prospective observational study, 67 patients with idiopathic PD underwent polysomnography. Those with moderate-severe OSA were offered CPAP therapy. Subjects were divided into those without OSA (OSA-), and those with OSA (OSA+)...
May 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29684315/sleep-disorders-in-patients-with-post-traumatic-stress-disorder
#3
REVIEW
Ali A El-Solh, Usman Riaz, Jasmine Roberts
A growing body of evidence supports a bidirectional relationship between post-traumatic stress disorder (PTSD) and sleep disturbances. Fragmented sleep induced by sleep-related breathing disorders, insomnia, and nightmares impacts recovery and treatment outcomes and worsens PTSD symptoms. Despite recent attention, management of these disorders has been unrewarding in the setting of PTSD. This review summarizes the evidence for empirically supported treatments of these sleep ailments as it relates to PTSD including psychotherapeutic and pharmacologic interventions...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29617049/parents-of-children-referred-to-a-sleep-laboratory-for-disordered-breathing-reported-anxiety-daytime-sleepiness-and-poor-sleep-quality
#4
Marion Cadart, Livio De Sanctis, Sonia Khirani, Alessandro Amaddeo, Lisa Ouss, Brigitte Fauroux
AIM: We evaluated the impact that having a child with sleep-disordered breathing had on their parents, including their own sleep quality. METHODS: Questionnaires were completed by 96 parents of 86 children referred for a sleep study or control of continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) at the sleep laboratory of the Necker Hospital, Paris, France, between October 2015 and January 2016. The questionnaires evaluated anxiety and depression, family functioning, the parents' quality of life, daytime sleepiness and sleep quality RESULTS: The children had a mean age of seven ±5 years and most of the responses (79%) came from their mothers...
April 4, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29454715/-sleepiness-continuous-positive-airway-pressure-and-the-obstructive-sleep-apnea-hypopnea-syndrome
#5
REVIEW
L Lerousseau
Excessive daytime sleepiness is a major symptom in cases of the obstructive sleep apnea-hypopnea syndrome. Most often, it is vastly improved by treatment with continuous positive airway pressure (CPAP). The most effective way to confirm its disappearance is through wakefulness maintenance testing. If residual sleepiness remains, despite CPAP, further diagnostic investigation must be carried out. Firstly, it must be assessed whether the treatment is fully effective (apnea hypopnea index<10/h) by examining flow limitations under treatment (polysomnography) and whether it is sufficiently used (>6h/night)...
February 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29351819/patient-reported-outcomes-in-older-adults-with-obstructive-sleep-apnea-treated-with-continuous-positive-airway-pressure-therapy
#6
Jennifer Pallansch, Yiping Li, James Bena, Lu Wang, Nancy Foldvary-Schaefer
STUDY OBJECTIVES: Although continuous positive airway pressure (CPAP) therapy is regarded as the gold standard treatment for obstructive sleep apnea (OSA) in adults, outcomes in older patients are limited. This study examines the effect of CPAP therapy in older adults with OSA (older than 60 years) compared to younger adults (age 18 to 60 years) to inform the current standard of practice. METHODS: We performed a retrospective study with a convenience sample to compare responses to CPAP treatment in older versus younger adults with OSA using validated, patient-reported outcomes (PROs)...
February 15, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29330769/comorbid-insomnia-and-sleep-apnea-in-veterans-with-post-traumatic-stress-disorder
#7
Ali A El-Solh, David Adamo, Thomas Kufel
PURPOSE: The purpose of this study was to determine the impact of insomnia in Veterans with post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) on health-related outcomes before and after 12 weeks of continuous positive airway pressure (CPAP) treatment. METHODS: We conducted a prospective cohort study of Veterans with PTSD and documented apnea hypopnea index (AHI) ≥ 5 with and without clinically significant insomnia as determined by the Insomnia Severity Index (ISI)...
March 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29296051/effects-of-continuous-positive-airway-pressure-on-anxiety-depression-and-major-cardiac-and-cerebro-vascular-events-in-obstructive-sleep-apnea-patients-with-and-without-coronary-artery-disease
#8
Ming-Chung Lee, Yu-Chih Shen, Ji-Hung Wang, Yu-Ying Li, Tzu-Hsien Li, En-Ting Chang, Hsiu-Mei Wang
Objective: Obstructive sleep apnea (OSA) is associated with bad cardiovascular outcomes and a high prevalence of anxiety and depression. This study investigated the effects of continuous positive airway pressure (CPAP) on the severity of anxiety and depression in OSA patients with or without coronary artery disease (CAD) and on the rate of cardio- and cerebro-vascular events in those with OSA and CAD. Materials and Methods: This prospective study included patients with moderate-to-severe OSA, with or without a recent diagnosis of CAD; all were started on CPAP therapy...
October 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29106789/depression-and-obstructive-sleep-apnea
#9
Milada Hobzova, Jan Prasko, Jakub Vanek, Marie Ociskova, Samuel Genzor, Michaela Holubova, Ales Grambal, Klara Latalova
OBJECTIVE: Obstructive sleep apnea (OSA), is described as intermittent interruptions or reductions in airflow which are initiated by an incomplete or complete collapse of the upper airways despite respiratory effort. When left untreated, OSA is connected with comorbid conditions, such as cardiovascular and metabolic illnesses. METHOD: The PubMed database was used to examine papers published until April 2017 using the subsequent terms: "obstructive sleep apnea" or "obstructive sleep apnoea" and "depression" in successive combination with "CPAP (continuous positive airway pressure)", "therapy", "pharmacotherapy", "psychotherapy", "cognitive behavioral therapy" or "quality of life"...
October 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28866718/hypersomnia-and-cognitive-impairment-in-a-patient-with-bipolar-disorder-a-case-report
#10
Katarzyna Szaulińska, Anna Antosik-Wójcińska, Ewa Paszkowska, Łukasz Święcicki, Marek Jarema, Adam Wichniak
OBJECTIVES: Obstructive sleep apnea (OSA) is a common clinical problem that can have serious health consequences and complicate the course of mental disorders. It is estimated that the prevalence of sleep apnea in patients with bipolar disorder can be 21-47.5%. Some symptoms of OSA are the same as the symptoms of depression: daytime drowsiness, cognitive dysfunction, decreased drive, apathy, depressed mood, anhedonia. METHODS: We present a case of a patient whose depressive symptoms persisted despite repeated changes of pharmacological treatment and were exacerbated by severe sleep disorder...
June 18, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/28759181/cognitive-function-and-depressivity-before-and-after-cpap-treatment-in-obstructive-sleep-apnea-patients
#11
Milada Hobzova, Lia Hubackova, Jakub Vanek, Samuel Genzor, Marie Ociskova, Ales Grambal, Jan Prasko
OBJECTIVE: The target of the investigation was to find if there is any improvement of depressive symptoms and cognitive functioning after continuous positive airway pressure (CPAP) treatment in the severe obstructive apnea (OSA) patients. METHOD: The study included 59 patients treated with CPAP for OSA in the Sleep Laboratory of the Department of Respiratory Medicine. Thirty-eight patients were treated with CPAP for one month, and twenty-one patients were in a control group...
July 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28625382/impact-of-continuous-positive-airway-pressure-and-oxygen-on-health-status-in-patients-with-coronary-heart-disease-cardiovascular-risk-factors-and-obstructive-sleep-apnea-a-heart-biomarker-evaluation-in-apnea-treatment-heartbeat-analysis
#12
RANDOMIZED CONTROLLED TRIAL
Eldrin F Lewis, Rui Wang, Naresh Punjabi, Daniel J Gottlieb, Stuart F Quan, Deepak L Bhatt, Sanjay R Patel, Reena Mehra, Roger S Blumenthal, Jia Weng, Michael Rueschman, Susan Redline
INTRODUCTION: Obstructive sleep apnea (OSA) is associated with impaired health-related quality of life (HRQL). Treatment with continuous positive airway pressure (CPAP) has variable impacts on HRQL, and this may be influenced by patient's tolerance of therapy. The objective is to determine the impact of nocturnal supplemental oxygen (NSO) and CPAP on HRQL compared with healthy lifestyle education (HLSE) in individuals with OSA. METHODS: Patients with coronary heart disease (CHD) or at least 3 major CHD risk factors with apnea-hypopnea index of 15 to 50 events/h were randomized to CPAP, NSO, or HLSE...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28330459/a-prospective-observational-study-to-evaluate-the-effect-of-social-and-personality-factors-on-continuous-positive-airway-pressure-cpap-compliance-in-obstructive-sleep-apnoea-syndrome
#13
Atul Gulati, Masood Ali, Mike Davies, Tim Quinnell, Ian Smith
BACKGROUND: Compliance with CPAP treatment for OSAS is not reliably predicted by the severity of symptoms or physiological variables. We examined a range of factors which could be measured before CPAP initiation to look for predictors of compliance. METHODS: This was a prospective cohort-study of CPAP treatment for OSAS, recording; socio-economic status, education, type D personality and clinician's prediction of compliance. RESULTS: We recruited 265 subjects, of whom 221 were still using CPAP at 6 months; median age 53 years, M: F, 3...
March 22, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28289449/does-personality-play-a-role-in%C3%A2-continuous-positive-airway-pressure-compliance
#14
REVIEW
Emily L Maschauer, Donna M Fairley, Renata L Riha
KEY POINTS: Continuous positive airway pressure (CPAP) adherence is low among individuals with obstructive sleep apnoea.Type D personality and high scores on the depression and hypochondriasis scales on the Minnesota Multiphasic Personality Inventory (MMPI) have been identified as factors contributing to non-compliance with CPAP.Further research into personality type may assist in understanding why some people adhere to CPAP, while others fail. Obstructive sleep apnoea (OSA) is a condition characterised by repetitive, intermittent partial or complete collapse/obstruction of the upper airway during sleep...
March 2017: Breathe
https://www.readbyqxmd.com/read/28007359/neurocognitive-function-in-patients-with-residual-excessive-sleepiness-from-obstructive-sleep-apnea-a-prospective-controlled-study
#15
Ksdy S Werli, Leonardo J Otuyama, Paulo H Bertolucci, Camila F Rizzi, Christian Guilleminault, Sergio Tufik, Dalva Poyares
OBJECTIVE: This study aimed to evaluate neurocognitive function in adult patients with residual excessive sleepiness (RES) after appropriate treatment of obstructive sleep apnea (OSA) with CPAP and good adherence to treatment. METHODS: This was a prospective controlled study. We included patients of both sexes, aged 35-60 years with OSA and an apnea-hypopnea index >20 ev/h, effectively treated with CPAP, but with a residual Epworth Sleepiness Scale score ≥11...
October 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27797160/pathogenesis-of-central-and-complex-sleep-apnoea
#16
REVIEW
Jeremy E Orr, Atul Malhotra, Scott A Sands
Central sleep apnoea (CSA) - the temporary absence or diminution of ventilatory effort during sleep - is seen in a variety of forms including periodic breathing in infancy and healthy adults at altitude and Cheyne-Stokes respiration in heart failure. In most circumstances, the cyclic absence of effort is paradoxically a consequence of hypersensitive ventilatory chemoreflex responses to oppose changes in airflow, that is elevated loop gain, leading to overshoot/undershoot ventilatory oscillations. Considerable evidence illustrates overlap between CSA and obstructive sleep apnoea (OSA), including elevated loop gain in patients with OSA and the presence of pharyngeal narrowing during central apnoeas...
January 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27707442/nasal-dilator-strip-is-an-effective-placebo-intervention-for-severe-obstructive-sleep-apnea
#17
Fabiana Yagihara, Geraldo Lorenzi-Filho, Rogerio Santos-Silva
STUDY OBJECTIVES: The aim of this study was to evaluate the effects of nasal dilator strip (NDS) as a placebo intervention compared with continuous positive airway pressure (CPAP) treatment in patients with severe obstructive sleep apnea (OSA). METHODS: Patients were treated with both NDS and nasal CPAP. The sequence was randomized and interposed by 15 days of washout. Polysomnography was performed at baseline and on the first night of intervention with NDS and CPAP (titration)...
February 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27583668/residual-excessive-sleepiness-in-patients-with-obstructive-sleep-apnea-on-treatment-with-continuous-positive-airway-pressure
#18
Eptehal M Dongol, Adrian J Williams
PURPOSE OF REVIEW: One of the most common causes of excessive daytime sleepiness in clinical practice is obstructive sleep apnea syndrome (OSAS). So far, continuous positive airway pressure (CPAP) is the most effective treatment for OSA. Some of the patients do not improve on CPAP and remain sleepy despite using CPAP.This review provides updated information about the possible causes of residual sleepiness whilst using the CPAP in patients with OSAS. RECENT FINDINGS: Prevalence of OSAS has increased recently to 23...
November 2016: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27334512/upper-airway-variation-and-frequent-alcohol-consumption-can-affect-compliance-with-continuous-positive-airway-pressure
#19
Jong In Jeong, Hyo Yeol Kim, Sang Duk Hong, Gwanghui Ryu, Su Jin Kim, Kyung Eun Lee, Hun-Jong Dhong, Seung-Kyu Chung
OBJECTIVES: Compliance with continuous positive airway pressure (CPAP) treatment remains a primary concern for improving treatment outcomes of obstructive sleep apnea. There are few studies that have considered the role of upper airway anatomy on the compliance with CPAP. We hypothesized that upper airway anatomy would influence the compliance with CPAP. METHODS: One hundred out of 161 consecutive patients were enrolled in this study. The following possible determinants were tested against CPAP use: demographic and anthropometric data, minimal cross-sectional area on acoustic rhinometry, cephalometric and polysomnographic data, questionnaires of Epworth sleepiness scale and Beck depression index, and histories of previous upper airway surgery, degree of nasal obstruction, daily cigarette consumption, and weekly frequency of alcohol intake...
December 2016: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/27181196/continuous-positive-airway-pressure-improves-quality-of-life-in-women-with-obstructive-sleep-apnea-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Francisco Campos-Rodriguez, Carlos Queipo-Corona, Carmen Carmona-Bernal, Bernabe Jurado-Gamez, Jose Cordero-Guevara, Nuria Reyes-Nuñez, Fernanda Troncoso-Acevedo, Araceli Abad-Fernandez, Joaquin Teran-Santos, Julian Caballero-Rodriguez, Mercedes Martin-Romero, Ana Encabo-Motiño, Lirios Sacristan-Bou, Javier Navarro-Esteva, Maria Somoza-Gonzalez, Juan F Masa, Maria A Sanchez-Quiroga, Beatriz Jara-Chinarro, Belen Orosa-Bertol, Miguel A Martinez-Garcia
RATIONALE: Continuous positive airway pressure (CPAP) is the treatment of choice in patients with symptomatic obstructive sleep apnea (OSA). CPAP treatment improves quality of life (QoL) in men with OSA, but its role in women has not yet been assessed. OBJECTIVES: To investigate the effect of CPAP on QoL in women with moderate to severe OSA. METHODS: We conducted a multicenter, open-label randomized controlled trial in 307 consecutive women diagnosed with moderate to severe OSA (apnea-hypopnea index, ≥15) in 19 Spanish sleep units...
November 15, 2016: American Journal of Respiratory and Critical Care Medicine
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