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https://www.readbyqxmd.com/read/29163049/tagging-of-endogenous-bk-channels-with-a-fluorogen-activating-peptide-reveals-%C3%AE-4-mediated-control-of-channel-clustering-in-cerebellum
#1
Christopher P Pratt, Dika A Kuljis, Gregg E Homanics, Jianjun He, Dmytro Kolodieznyi, Srikanth Dudem, Mark A Hollywood, Alison L Barth, Marcel P Bruchez
BK channels are critical regulators of neuronal activity, controlling firing, neurotransmitter release, cerebellar function, and BK channel mutations have been linked to seizure disorders. Modulation of BK channel gating is well characterized, regulated by accessory subunit interactions, intracellular signaling pathways, and membrane potential. In contrast, the role of intracellular trafficking mechanisms in controlling BK channel function, especially in live cells, has been less studied. Fluorogen-activating peptides (FAPs) are well-suited for trafficking and physiological studies due to the binding of malachite green (MG)-based dyes with sub-nanomolar affinity to the FAP, resulting in bright, photostable, far-red fluorescence...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29161225/from-sexual-desire-discrepancies-to-desirable-sex-creating-the-optimal-connection
#2
Peggy J Kleinplatz, Maxime Charest, Shannon Lawless, Marlene Neufeld, Robert Neufeld, Danielle Pratt, A Dana Ménard, Bogdan Buduru, Lianne Rosen
Beginning in 2005, our team conducted a series of studies on optimal sexual experiences. We have applied our findings to develop a group therapy intervention for couples presenting with low sexual desire/frequency and sexual desire discrepancy. The goal was to improve the quality of erotic intimacy by focusing on such elements as being fully embodied during sex, increasing authenticity, trustworthiness and vulnerability. Twenty-eight heterosexual individuals (14 couples) were seen in 16 hours of couples group therapy...
November 21, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29160115/linking-participatory-action-research-on-health-systems-to-justice-in-global-health-a-case-study-of-the-maternal-and-neonatal-implementation-for-equitable-health-systems-project-in-rural-uganda
#3
Bridget Pratt, Adnan A Hyder
An ethical framework called "research for health justice" provides initial guidance on how to link health systems research in low- and middle-income countries to health equity. To further develop the largely conceptual framework, we tested its guidance against the experience of the Maternal and Neonatal Implementation for Equitable Health Systems (Manifest) project, which was performed in rural Uganda by researchers from Makerere University. We conducted 21 in-depth interviews with investigators and research implementers, directly observed study sites, and reviewed study-related documents...
November 1, 2017: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/29158323/fgf8-morphogen-gradients-are-differentially-regulated-by-heparan-sulphotransferases-hs2st-and-hs6st1-in-the-developing-brain
#4
Wai-Kit Chan, David J Price, Thomas Pratt
Fibroblast growth factor (FGF) morphogen signalling through the evolutionarily ancient Extracellular signaling Regulated Kinase/Mitogen Activated Protein Kinase (ERK/MAPK) pathway recurs in many neural and non-neural developmental contexts and understanding the mechanisms that regulate FGF/ERK function are correspondingly important. The glycosaminoglycan heparan sulphate (HS) binds to FGFs and exists in an enormous number of differentially sulphated forms produced by the action of HS modifying enzymes so has the potential to present an extremely large amount of information in FGF/ERK signalling...
November 20, 2017: Biology Open
https://www.readbyqxmd.com/read/29155679/antidepressant-use-among-persons-aged-12-and-over-united-states-2011-2014
#5
Laura A Pratt, Debra J Brody, Qiuping Gu
Key findings Data from the National Health and Nutrition Examination Survey ● During 2011-2014, 12.7% of persons aged 12 and over, 8.6% of males, and 16.5% of females took antidepressant medication in the past month. ● For both males and females, non-Hispanic white persons were more likely to take antidepressant medication compared with those of other race and Hispanic-origin groups. ● One-fourth of persons who took antidepressant medication had done so for 10 years or more. ● Antidepressant use increased from 1999 to 2014...
August 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/29141464/understanding-posttraumatic-growth-of-paratriathletes-with-acquired-disability
#6
Chris Hammer, Leslie Podlog, Ross Wadey, Nick Galli, Anjali J Forber-Pratt, Maria Newton, Morgan Hall, Lindsey Greviskes
PURPOSE: To examine the relevance of key components of Organismic Valuing Theory of Growth through Adversity in understanding posttraumatic growth amongst paratriathletes with acquired disability. METHODS: Semi-structured interviews informed by organismic valuing theory of growth through adversity were conducted with 14 elite paratriathletes (eight male, six female). To increase the likelihood that participants had experienced posttraumatic growth, a short form of the Posttraumatic Growth Inventory was completed prior to interview participation...
November 15, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29137573/can-we-reduce-the-prevalence-of-persistent-opioid-use-after-surgery-by-predicting-the-future
#7
N L Pratt, E E Roughead
No abstract text is available yet for this article.
November 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29137560/randomized-trial-of-interventions-for-smoking-cessation-among-medicaid-beneficiaries-with-mental-illness
#8
Mary F Brunette, Sarah I Pratt, Stephen J Bartels, Emily A Scherer, Stacey C Sigmon, Joelle C Ferron, Meghan Santos, Gail E Williams, Samuel Kosydar, Rosemarie S Wolfe, Doris Lotz, Kelley Capuchino
OBJECTIVE: Medicaid beneficiaries with severe mental illnesses are a financially disadvantaged group with high rates of smoking and poor cessation outcomes. This study examined whether abstinence-contingent monetary incentives improved outcomes when added to cessation treatments at community mental health centers: prescriber visit for pharmacotherapy only (PV only), prescriber visit and facilitated quitline (PV+Q), and prescriber visit and telephone cognitive-behavioral therapy (PV+CBT)...
November 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29135681/piercing-and-metal-sensitivity-extended-analysis-of-the-north-american-contact-dermatitis-group-data-2007-2014
#9
Erin M Warshaw, Kelly A Aschenbeck, Joel G DeKoven, Howard I Maibach, James S Taylor, Denis Sasseville, Donald V Belsito, Joseph F Fowler, Kathryn A Zug, Matthew J Zirwas, Anthony F Fransway, Vincent A DeLeo, James G Marks, Melanie D Pratt, Toby Mathias
BACKGROUND: Body piercing provides a unique route of metal exposure. OBJECTIVE: The aim of this study was to update previous analyses using the North American Contact Dermatitis Group data comparing pierced and unpierced individuals. METHODS: This was a retrospective cross-sectional analysis of 17,912 patients patch tested by the North American Contact Dermatitis Group from 2007 to 2014 for demographics, positive reactions to metals (nickel, cobalt, chromium), and detailed analysis of nickel reactions by age, sex, and source of exposure...
November 2017: Dermatitis
https://www.readbyqxmd.com/read/29133314/decisional-needs-assessment-of-patients-with-complex-care-needs-in-primary-care-a-participatory-systematic-mixed-studies-review-protocol
#10
Mathieu Bujold, Pierre Pluye, France Légaré, Jeannie Haggerty, Genevieve C Gore, Reem El Sherif, Marie-Eve Poitras, Marie-Claude Beaulieu, Marie-Dominique Beaulieu, Paula L Bush, Yves Couturier, Beatrice Débarges, Justin Gagnon, Anik Giguère, Roland Grad, Vera Granikov, Serge Goulet, Catherine Hudon, Bernardo Kremer, Edeltraut Kröger, Irina Kudrina, Bertrand Lebouché, Christine Loignon, Marie-Therese Lussier, Cristiano Martello, Quynh Nguyen, Rebekah Pratt, Benoit Rihoux, Ellen Rosenberg, Isabelle Samson, Nicolas Senn, David Li Tang, Masashi Tsujimoto, Isabelle Vedel, Bruno Ventelou, Michel Wensing
INTRODUCTION: Patients with complex care needs (PCCNs) often suffer from combinations of multiple chronic conditions, mental health problems, drug interactions and social vulnerability, which can lead to healthcare services overuse, underuse or misuse. Typically, PCCNs face interactional issues and unmet decisional needs regarding possible options in a cascade of interrelated decisions involving different stakeholders (themselves, their families, their caregivers, their healthcare practitioners)...
November 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29122874/whole-genome-sequences-of-variants-of-bacillus-anthracis-sterne-and-their-toxin-gene-deletion-mutants
#11
A Staab, R D Plaut, C Pratt, S P Lovett, M R Wiley, T D Biggs, R C Bernhards, L C Beck, G F Palacios, S Stibitz, K L Jones, B G Goodwin, M A Smith, S Sozhamannan
Here, we report the draft genome sequences of three laboratory variants of Bacillus anthracis Sterne and their double (Δlef Δcya) and triple (Δpag Δlef Δcya) toxin gene deletion derivatives.
November 9, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29122047/antipsychotic-polypharmacy-in-older-australians
#12
Lisa M Kalisch Ellett, Nicole L Pratt, Mhairi Kerr, Elizabeth E Roughead
BACKGROUND: Antipsychotics are commonly used, and the rate of use is highest, among those aged 65 years or over, where the risk of adverse events is also high. Up to 20% of younger adults use more than one antipsychotic concurrently; however there are few studies on the prevalence of antipsychotic polypharmacy in older people. We aimed to analyze antipsychotic use in elderly Australians, focusing on the prevalence of antipsychotic polypharmacy and the use of medicines to manage adverse events associated with antipsychotics...
November 10, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29116681/chiral-imprinting-in-the-gas-phase
#13
David W Pratt, Brooks H Pate
Undoing the twist: Recent successful attempts to change the relative populations of two otherwise identical enantiomers of a large gas-phase molecule using resonant microwave fields are highlighted. Specifically, the population of a specific enantiomer of a chiral terpene could be enhanced relative to the other enantiomer by the application of a sequence of microwave pulses in a phase- and polarization-controlled manner.
November 8, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29112326/real-world-challenges-and-unmet-needs-in-the-diagnosis-and-treatment-of-suspected-invasive-pulmonary-aspergillosis-in-patients-with-hematological-diseases-an-illustrative-case-study
#14
Martin Hoenigl, Juergen Prattes, Peter Neumeister, Albert Wölfler, Robert Krause
Recent years have seen important advances in the diagnosis of invasive pulmonary aspergillosis (IPA), complemented by the introduction of new therapies. Despite this, IPA remains a major cause of infection-related mortality in patients with hematological diseases. There are two main reasons for this. First, diagnosis of IPA remains a challenge, since risk factors and the clinical, radiological and mycological presentations vary not only by fungal disease stage, but also by patient group (e.g. neutropenic versus non-neutropenic patients)...
November 7, 2017: Mycoses
https://www.readbyqxmd.com/read/29102704/primary-sclerosing-cholangitis-is-not-rare-among-blacks-in-a-multi-center-north-american-consortium
#15
David Goldberg, Cynthia Levy, Kidist Yimam, Stuart Gordon, Lisa Forman, Elizabeth Verna, Lei Yu, Robert Rahimi, Kathleen Schwarz, Bertus Eksteen, Daniel Pratt, Thomas Boyer, David Assis, Christopher Bowlus
No abstract text is available yet for this article.
November 1, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29102571/multisite-investigation-of-outcomes-with%C3%A2-implementation-of-cyp2c19-genotype-guided-antiplatelet-therapy-after-percutaneous-coronary-intervention
#16
Larisa H Cavallari, Craig R Lee, Amber L Beitelshees, Rhonda M Cooper-DeHoff, Julio D Duarte, Deepak Voora, Stephen E Kimmel, Caitrin W McDonough, Yan Gong, Chintan V Dave, Victoria M Pratt, Tameka D Alestock, R David Anderson, Jorge Alsip, Amer K Ardati, Brigitta C Brott, Lawrence Brown, Supatat Chumnumwat, Michael J Clare-Salzler, James C Coons, Joshua C Denny, Chrisly Dillon, Amanda R Elsey, Issam S Hamadeh, Shuko Harada, William B Hillegass, Lindsay Hines, Richard B Horenstein, Lucius A Howell, Linda J B Jeng, Mark D Kelemen, Y M Lee, Oyunbileg Magvanjav, May Montasser, David R Nelson, Edith A Nutescu, Devon C Nwaba, Ruth E Pakyz, Kathleen Palmer, Josh F Peterson, Toni I Pollin, Alison H Quinn, Shawn W Robinson, Jamie Schub, Todd C Skaar, D Max Smith, Vindhya B Sriramoju, Petr Starostik, Tomasz P Stys, James M Stevenson, Nicholas Varunok, Mark R Vesely, Dyson T Wake, Karen E Weck, Kristin W Weitzel, Russell A Wilke, James Willig, Richard Y Zhao, Rolf P Kreutz, George A Stouffer, Philip E Empey, Nita A Limdi, Alan R Shuldiner, Almut G Winterstein, Julie A Johnson
OBJECTIVES: This multicenter pragmatic investigation assessed outcomes following clinical implementation of CYP2C19 genotype-guided antiplatelet therapy after percutaneous coronary intervention (PCI). BACKGROUND: CYP2C19 loss-of-function alleles impair clopidogrel effectiveness after PCI. METHODS: After clinical genotyping, each institution recommended alternative antiplatelet therapy (prasugrel, ticagrelor) in PCI patients with a loss-of-function allele...
October 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29101208/nf-kappab-at-the-crossroads-of-normal-mammary-gland-biology-and-the-pathogenesis-and-prevention-of-brca1-mutated-breast-cancer
#17
M A Christine Pratt, Andrea Sau, Miguel A Cabrita
Recent studies have shown that progesterone receptor (PR)-expressing cells respond to progesterone in part through the induction of the receptor activator of NF-kappaB ligand (RANKL) in which acts in a paracrine manner to induce expansion of a RANK-expressing luminal progenitor cell population. The RANK+ population in human breast tissue from carriers of BRCA1 mutations (BRCA1mut/+) as well as the luminal progenitor population in Brca1-deficient mouse mammary glands is abnormally amplified. Remarkably, mouse Brca1+/- and human BRCA1mut/+ progenitor cells are able to form colonies in vitro in the absence of progesterone demonstrating a hormone-independent proliferative capacity...
November 3, 2017: Cancer Prevention Research
https://www.readbyqxmd.com/read/29101056/combined-small-cell-carcinoma-of-the-lung-is-it-a-single-entity
#18
Xiaoliang Zhao, Justine N McCutcheon, Bhaskar Kallakury, Joeffrey J Chahine, Drew Pratt, Mark Raffeld, Yulong Chen, Changli Wang, Giuseppe Giaccone
BACKGROUND: Small-cell lung carcinoma (SCLC) accounts for 15-20% of all lung cancers, with combined SCLC (CSCLC) comprising 2-5%. Little is known about the clinical characteristics and molecular changes associated with the various histologic components. METHODS: 205 SCLC cases were resected between 2005-2015. Clinical and pathologic features were analyzed. All CSCLC cases were confirmed by histology and immunohistochemistry. The individual components were microdissected using a novel automated dissection system and DNA was extracted and subjected to targeted exome sequencing...
October 31, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/29099468/assessing-acute-symptoms-related-to-occupational-exposures-among-nail-salon-technicians
#19
Derek G Shendell, Judith M Graber, Lindsey J Milich, Michael E Pratt
OBJECTIVE: This cross-sectional field study evaluated potential associations between acute symptoms among nail technicians and exposure of chemical hazards in New Jersey salons. METHODS: In 2016, an in-person safety and health survey was conducted. Data were gathered on symptoms, demographics, work history, tobacco use, area and/or task ventilation, use of personal protective equipment (PPE), and safety training. Workplace hazards were identified by observational survey during site visit walk-throughs...
November 2, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29099225/gw170817-observation-of-gravitational-waves-from-a-binary-neutron-star-inspiral
#20
B P Abbott, R Abbott, T D Abbott, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Afrough, B Agarwal, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, B Allen, G Allen, A Allocca, P A Altin, A Amato, A Ananyeva, S B Anderson, W G Anderson, S V Angelova, S Antier, S Appert, K Arai, M C Araya, J S Areeda, N Arnaud, K G Arun, S Ascenzi, G Ashton, M Ast, S M Aston, P Astone, D V Atallah, P Aufmuth, C Aulbert, K AultONeal, C Austin, A Avila-Alvarez, S Babak, P Bacon, M K M Bader, S Bae, M Bailes, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, S Banagiri, J C Barayoga, S E Barclay, B C Barish, D Barker, K Barkett, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, S D Barthelmy, J Bartlett, I Bartos, R Bassiri, A Basti, J C Batch, M Bawaj, J C Bayley, M Bazzan, B Bécsy, C Beer, M Bejger, I Belahcene, A S Bell, B K Berger, G Bergmann, S Bernuzzi, J J Bero, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, C R Billman, J Birch, R Birney, O Birnholtz, S Biscans, S Biscoveanu, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, J Blackman, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, N Bode, M Boer, G Bogaert, A Bohe, F Bondu, E Bonilla, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, K Bossie, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, J E Broida, A F Brooks, D A Brown, D D Brown, S Brunett, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, M Cabero, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T A Callister, E Calloni, J B Camp, M Canepa, P Canizares, K C Cannon, H Cao, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, M F Carney, G Carullo, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, P Cerdá-Durán, G Cerretani, E Cesarini, S J Chamberlin, M Chan, S Chao, P Charlton, E Chase, E Chassande-Mottin, D Chatterjee, K Chatziioannou, B D Cheeseboro, H Y Chen, X Chen, Y Chen, H-P Cheng, H Chia, A Chincarini, A Chiummo, T Chmiel, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, A J K Chua, S Chua, A K W Chung, S Chung, G Ciani, R Ciolfi, C E Cirelli, A Cirone, F Clara, J A Clark, P Clearwater, F Cleva, C Cocchieri, E Coccia, P-F Cohadon, D Cohen, A Colla, C G Collette, L R Cominsky, M Constancio, L Conti, S J Cooper, P Corban, T R Corbitt, I Cordero-Carrión, K R Corley, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, P B Covas, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, J D E Creighton, T D Creighton, J Cripe, S G Crowder, T J Cullen, A Cumming, L Cunningham, E Cuoco, T Dal Canton, G Dálya, S L Danilishin, S D'Antonio, K Danzmann, A Dasgupta, C F Da Silva Costa, V Dattilo, I Dave, M Davier, D Davis, E J Daw, B Day, S De, D DeBra, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, N Demos, T Denker, T Dent, R De Pietri, V Dergachev, R De Rosa, R T DeRosa, C De Rossi, R DeSalvo, O de Varona, J Devenson, S Dhurandhar, M C Díaz, T Dietrich, L Di Fiore, M Di Giovanni, T Di Girolamo, A Di Lieto, S Di Pace, I Di Palma, F Di Renzo, Z Doctor, V Dolique, F Donovan, K L Dooley, S Doravari, I Dorrington, R Douglas, M Dovale Álvarez, T P Downes, M Drago, C Dreissigacker, J C Driggers, Z Du, M Ducrot, R Dudi, P Dupej, S E Dwyer, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, R A Eisenstein, R C Essick, D Estevez, Z B Etienne, T Etzel, M Evans, T M Evans, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, S Farinon, B Farr, W M Farr, E J Fauchon-Jones, M Favata, M Fays, C Fee, H Fehrmann, J Feicht, M M Fejer, A Fernandez-Galiana, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, D Finstad, I Fiori, D Fiorucci, M Fishbach, R P Fisher, M Fitz-Axen, R Flaminio, M Fletcher, H Fong, J A Font, P W F Forsyth, S S Forsyth, J-D Fournier, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, E M Fries, P Fritschel, V V Frolov, P Fulda, M Fyffe, H Gabbard, B U Gadre, S M Gaebel, J R Gair, L Gammaitoni, M R Ganija, S G Gaonkar, C Garcia-Quiros, F Garufi, B Gateley, S Gaudio, G Gaur, V Gayathri, N Gehrels, G Gemme, E Genin, A Gennai, D George, J George, L Gergely, V Germain, S Ghonge, Abhirup Ghosh, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, L Glover, E Goetz, R Goetz, S Gomes, B Goncharov, G González, J M Gonzalez Castro, A Gopakumar, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, A Grado, C Graef, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, E M Gretarsson, P Groot, H Grote, S Grunewald, P Gruning, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, O Halim, B R Hall, E D Hall, E Z Hamilton, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, M D Hannam, O A Hannuksela, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, C-J Haster, K Haughian, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, A W Heptonstall, M Heurs, S Hild, T Hinderer, W C G Ho, D Hoak, D Hofman, K Holt, D E Holz, P Hopkins, C Horst, J Hough, E A Houston, E J Howell, A Hreibi, Y M Hu, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, N Indik, R Inta, G Intini, H N Isa, J-M Isac, M Isi, B R Iyer, K Izumi, T Jacqmin, K Jani, P Jaranowski, S Jawahar, F Jiménez-Forteza, W W Johnson, N K Johnson-McDaniel, D I Jones, R Jones, R J G Jonker, L Ju, J Junker, C V Kalaghatgi, V Kalogera, B Kamai, S Kandhasamy, G Kang, J B Kanner, S J Kapadia, S Karki, K S Karvinen, M Kasprzack, W Kastaun, M Katolik, E Katsavounidis, W Katzman, S Kaufer, K Kawabe, F Kéfélian, D Keitel, A J Kemball, R Kennedy, C Kent, J S Key, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, Chunglee Kim, J C Kim, K Kim, W Kim, W S Kim, Y-M Kim, S J Kimbrell, E J King, P J King, M Kinley-Hanlon, R Kirchhoff, J S Kissel, L Kleybolte, S Klimenko, T D Knowles, P Koch, S M Koehlenbeck, S Koley, V Kondrashov, A Kontos, M Korobko, W Z Korth, I Kowalska, D B Kozak, C Krämer, V Kringel, B Krishnan, A Królak, G Kuehn, P Kumar, R Kumar, S Kumar, L Kuo, A Kutynia, S Kwang, B D Lackey, K H Lai, M Landry, R N Lang, J Lange, B Lantz, R K Lanza, S L Larson, A Lartaux-Vollard, P D Lasky, M Laxen, A Lazzarini, C Lazzaro, P Leaci, S Leavey, C H Lee, H K Lee, H M Lee, H W Lee, K Lee, J Lehmann, A Lenon, E Leon, M Leonardi, N Leroy, N Letendre, Y Levin, T G F Li, S D Linker, T B Littenberg, J Liu, X Liu, R K L Lo, N A Lockerbie, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, G Lovelace, H Lück, D Lumaca, A P Lundgren, R Lynch, Y Ma, R Macas, S Macfoy, B Machenschalk, M MacInnis, D M Macleod, I Magaña Hernandez, F Magaña-Sandoval, L Magaña Zertuche, R M Magee, E Majorana, I Maksimovic, N Man, V Mandic, V Mangano, G L Mansell, M Manske, M Mantovani, F Marchesoni, F Marion, S Márka, Z Márka, C Markakis, A S Markosyan, A Markowitz, E Maros, A Marquina, P Marsh, F Martelli, L Martellini, I W Martin, R M Martin, D V Martynov, J N Marx, K Mason, E Massera, A Masserot, T J Massinger, M Masso-Reid, S Mastrogiovanni, A Matas, F Matichard, L Matone, N Mavalvala, N Mazumder, R McCarthy, D E McClelland, S McCormick, L McCuller, S C McGuire, G McIntyre, J McIver, D J McManus, L McNeill, T McRae, S T McWilliams, D Meacher, G D Meadors, M Mehmet, J Meidam, E Mejuto-Villa, A Melatos, G Mendell, R A Mercer, E L Merilh, M Merzougui, S Meshkov, C Messenger, C Messick, R Metzdorff, P M Meyers, H Miao, C Michel, H Middleton, E E Mikhailov, L Milano, A L Miller, B B Miller, J Miller, M Millhouse, M C Milovich-Goff, O Minazzoli, Y Minenkov, J Ming, C Mishra, S Mitra, V P Mitrofanov, G Mitselmakher, R Mittleman, D Moffa, A Moggi, K Mogushi, M Mohan, S R P Mohapatra, I Molina, M Montani, C J Moore, D Moraru, G Moreno, S Morisaki, S R Morriss, B Mours, C M 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On August 17, 2017 at 12∶41:04 UTC the Advanced LIGO and Advanced Virgo gravitational-wave detectors made their first observation of a binary neutron star inspiral. The signal, GW170817, was detected with a combined signal-to-noise ratio of 32.4 and a false-alarm-rate estimate of less than one per 8.0×10^{4}  years. We infer the component masses of the binary to be between 0.86 and 2.26  M_{⊙}, in agreement with masses of known neutron stars. Restricting the component spins to the range inferred in binary neutron stars, we find the component masses to be in the range 1...
October 20, 2017: Physical Review Letters
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