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https://www.readbyqxmd.com/read/28923812/primary-care-and-public-health-perspectives-on-integration-at-the-local-level-a-multi-state-study
#1
Rebekah Pratt, Beth Gyllstrom, Kim Gearin, David Hahn, Lisa VanRaemdonck, Kevin Peterson, Laura-Mae Baldwin
OBJECTIVE: The Institute of Medicine argues that the integration of primary care (PC) and public health (PH) is of paramount importance. We undertook this qualitative study to better understand how these collaborations function. DATA SOURCES: Investigators from PC and PH practice-based research networks in Colorado, Minnesota, Washington, and Wisconsin identified 40 key informants from the PH and PC fields within their respective states. STUDY DESIGN: The key informants participated in standardized, semistructured interviews...
September 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28922489/clinical-evaluation-of-the-newly-formatted-lateral-flow-device-for-invasive-pulmonary-aspergillosis
#2
Martin Hoenigl, Susanne Eigl, Sven Heldt, Wiebke Duettmann, Christopher Thornton, Juergen Prattes
The study evaluated the newly formatted Aspergillus-specific lateral-flow-device (LFD), and compared its performance to the original prototype "old" LFD test using BALF samples from 28 patients (14 patients with probable/proven invasive pulmonary aspergillosis [IPA] and 14 patients with no evidence for IPA). A total of 10/14 (71%) of BALF samples from patients with probable/proven IPA resulted positive with the new LFD, including 8/9 with true-positive and 2/5 with false-negative results with the old LFD. All 14 samples from patients without IPA resulted negative with the new LFD; specificity of the new LFD was significantly improved compared to the old LFD...
September 18, 2017: Mycoses
https://www.readbyqxmd.com/read/28918315/does-cognitive-behavioural-therapy-for-insomnia-improve-cognitive-performance-a-systematic-review-and-narrative-synthesis
#3
REVIEW
Vanessa Herbert, Simon D Kyle, Daniel Pratt
Individuals with insomnia report difficulties pertaining to their cognitive functioning. Cognitive behavioural therapy for insomnia (CBT-I) is associated with robust, long-term improvements in sleep parameters, however less is known about the impact of CBT-I on the daytime correlates of the disorder. A systematic review and narrative synthesis was conducted in order to summarise and evaluate the evidence regarding the impact of CBT-I on cognitive functioning. Reference databases were searched and studies were included if they assessed cognitive performance as an outcome of CBT-I, using either self-report questionnaires or cognitive tests...
July 12, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28916853/ironic-capture-top-down-expectations-exacerbate-distraction-in-visual-search
#4
Greg Huffman, Jason Rajsic, Jay Pratt
Ironic processing refers to the phenomenon where attempting to resist doing something results in a person doing that very thing. Here, we report three experiments investigating the role of ironic processing in visual search. In Experiment 1, we informed observers that they could predict the location of a salient color singleton in a visual search task and found that response times were slower in that condition than in a condition where the singleton's location was random. Experiment 2 used the same experimental design but did not inform participants of the color singleton's behavior...
September 15, 2017: Psychological Research
https://www.readbyqxmd.com/read/28916703/my-career-defining-moment-adrian-pratt
#5
(no author information available yet)
In 2001, an industry job saved my veterinary career. After six years in clinical practice, I had failed to find the job of my dreams. I was disengaged, disenchanted and looking for a way out. I was lost on my personal development journey.
September 16, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28915923/season-but-not-symbiont-state-drives-microbiome-structure-in-the-temperate-coral-astrangia-poculata
#6
Koty H Sharp, Zoe A Pratte, Allison H Kerwin, Randi D Rotjan, Frank J Stewart
BACKGROUND: Understanding the associations among corals, their photosynthetic zooxanthella symbionts (Symbiodinium), and coral-associated prokaryotic microbiomes is critical for predicting the fidelity and strength of coral symbioses in the face of growing environmental threats. Most coral-microbiome associations are beneficial, yet the mechanisms that determine the composition of the coral microbiome remain largely unknown. Here, we characterized microbiome diversity in the temperate, facultatively symbiotic coral Astrangia poculata at four seasonal time points near the northernmost limit of the species range...
September 15, 2017: Microbiome
https://www.readbyqxmd.com/read/28904136/neural-evidence-supports-a-dual-sensory-motor-role-for-insect-wings
#7
Brandon Pratt, Tanvi Deora, Thomas Mohren, Thomas Daniel
Flying insects use feedback from various sensory modalities including vision and mechanosensation to navigate through their environment. The rapid speed of mechanosensory information acquisition and processing compensates for the slower processing times associated with vision, particularly under low light conditions. While halteres in dipteran species are well known to provide such information for flight control, less is understood about the mechanosensory roles of their evolutionary antecedent, wings. The features that wing mechanosensory neurons (campaniform sensilla) encode remains relatively unexplored...
September 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28899697/implementation-of-a-human-podocyte-injury-model-of-chronic-kidney-disease-for-profiling-of-renoprotective-compounds
#8
Vivek C Abraham, Loan N Miller, Steve D Pratt, Brent Putman, Laura Kim, Sujatha M Gopalakrishnan, Andrew King
Degradation of podocyte structural integrity and function are hallmarks of proteinuric chronic kidney disease. In vivo, injury of podocytes manifests itself in the form of disruption of foot process morphology and associated cytoskeletal architecture, de-differentiation, and loss of adhesion to the glomerular basement membrane. Given the critical role played by this highly specialized cell type in maintaining glomerular filtration, there is a need for improved physiologically relevant cellular models that enable detection of disease-relevant indicators of podocyte perturbation...
September 9, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28898565/the-projected-burden-of-osteoarthritis-and-rheumatoid-arthritis-in-australia-a-population-level-analysis
#9
Ilana N Ackerman, Clare Pratt, Alexandra Gorelik, Danny Liew
OBJECTIVE: To forecast the prevalence and direct healthcare costs of osteoarthritis (OA) and rheumatoid arthritis (RA) in Australia to the year 2030. METHODS: An epidemiological model of the Australian population was developed. Data on the national prevalence of OA and RA were obtained from the Australian Bureau of Statistics (ABS) 2014-2015 National Health Survey. Future prevalence was estimated using ABS population projections for 2020, 2025 and 2030. Available government data on direct healthcare expenditure for OA and RA were modelled to forecast costs (in AUD) for the years 2020, 2025 and 2030, from the perspective of the Australian public healthcare system...
September 12, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28886028/traits-underlying-community-consequences-of-plant-intra-specific-diversity
#10
Luis Abdala-Roberts, Riley Pratt, Jessica D Pratt, Kailen A Mooney
A plant's performance and interactions with other trophic levels are recorgnized to be contingent upon plant diversity and underlying associational dynamics, but far less is known about the plant traits driving such phenomena. We manipulated diversity in plant traits using pairs of plant and a substitutive design to elucidate the mechanisms underlying diversity effects operating at a fine spatial scale. Specifically, we measured the effects of diversity in sex (sexual monocultures vs. male and female genotypes together) and growth rate (growth rate monocultures vs...
2017: PloS One
https://www.readbyqxmd.com/read/28885854/phenoxazine-a-privileged-scaffold-for-radical-trapping-antioxidants
#11
Luke A Farmer, Evan A Haidasz, Markus Griesser, Derek A Pratt
Diphenylamines are widely used to protect petroleum-derived products from autoxidation. Their efficacy as radical-trapping antioxidants (RTAs) relies on a balance of fast H-atom transfer kinetics and stability to one electron oxidation by peroxidic species. Both H-atom transfer and one-electron oxidation are enhanced by substitution with electron-donating substituents, such as the S-atom in phenothiazines, another important class of RTA. Herein we report the results of our investigations of the RTA activity of the structurally-related, but essentially ignored, phenoxazines...
September 8, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28882746/contributing-to-helping-to-achieve-the-un-sustainable-development-goals-truly-shifting-from-niche-to-norm
#12
EDITORIAL
Billie Giles-Corti, Jacqueline Kerr, Michael Pratt
No abstract text is available yet for this article.
September 5, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28880300/stop-this-waste-of-people-animals-and-money
#13
David Moher, Larissa Shamseer, Kelly D Cobey, Manoj M Lalu, James Galipeau, Marc T Avey, Nadera Ahmadzai, Mostafa Alabousi, Pauline Barbeau, Andrew Beck, Raymond Daniel, Robert Frank, Mona Ghannad, Candyce Hamel, Mona Hersi, Brian Hutton, Inga Isupov, Trevor A McGrath, Matthew D F McInnes, Matthew J Page, Misty Pratt, Kusala Pussegoda, Beverley Shea, Anubhav Srivastava, Adrienne Stevens, Kednapa Thavorn, Sasha van Katwyk, Roxanne Ward, Dianna Wolfe, Fatemeh Yazdi, Ashley M Yu, Hedyeh Ziai
No abstract text is available yet for this article.
September 6, 2017: Nature
https://www.readbyqxmd.com/read/28878730/stepping-to-the-beat-feasibility-and-potential-efficacy-of-a-home-based-auditory-cued-step-training-program-in-chronic-stroke
#14
Rachel L Wright, Simone Briony Brownless, David Pratt, Catherine M Sackley, Alan M Wing
BACKGROUND: Hemiparesis after stroke typically results in a reduced walking speed, an asymmetrical gait pattern and a reduced ability to make gait adjustments. The purpose of this pilot study was to investigate the feasibility and preliminary efficacy of home-based training involving auditory cueing of stepping in place. METHODS: Twelve community-dwelling participants with chronic hemiparesis completed two 3-week blocks of home-based stepping to music overlaid with an auditory metronome...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28877383/levels-of-interleukin-il-6-and-il-8-are-elevated-in-serum-and-bronchoalveolar-lavage-fluid-of-haematological-patients-with-invasive-pulmonary-aspergillosis
#15
Sven Heldt, Susanne Eigl, Juergen Prattes, Holger Flick, Jasmin Rabensteiner, Florian Prüller, Tobias Niedrist, Peter Neumeister, Albert Wölfler, Heimo Strohmaier, Robert Krause, Martin Hoenigl
Aspergillus spp. have been shown to induce T-helper cell (Th) 1 and Th17 subsets resulting in elevated levels of several cytokines. The objective of this study was to analyse a bundle of cytokines in serum and bronchoalveolar lavage fluid (BALF) in patients with and without invasive pulmonary aspergillosis (IPA). This nested case-control analysis included 10 patients with probable/proven IPA and 20 matched controls without evidence of IPA, out of a pool of prospectively enrolled (2014-2017) adult cases with underlying haematological malignancies and suspected pulmonary infection...
September 6, 2017: Mycoses
https://www.readbyqxmd.com/read/28874585/active-molecular-iodine-photochemistry-in-the-arctic
#16
Angela R W Raso, Kyle D Custard, Nathaniel W May, David Tanner, Matt K Newburn, Lawrence Walker, Ronald J Moore, L G Huey, Liz Alexander, Paul B Shepson, Kerri A Pratt
During springtime, the Arctic atmospheric boundary layer undergoes frequent rapid depletions in ozone and gaseous elemental mercury due to reactions with halogen atoms, influencing atmospheric composition and pollutant fate. Although bromine chemistry has been shown to initiate ozone depletion events, and it has long been hypothesized that iodine chemistry may contribute, no previous measurements of molecular iodine (I2) have been reported in the Arctic. Iodine chemistry also contributes to atmospheric new particle formation and therefore cloud properties and radiative forcing...
September 5, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28864511/what-does-the-futurologists-view-hold-for-vets
#17
Adrian Pratt
No abstract text is available yet for this article.
September 2, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28844632/patient-dissatisfaction-following-total-knee-arthroplasty-a-systematic-review-of-the-literature
#18
Rajitha Gunaratne, Dylan N Pratt, Joseph Banda, Daniel P Fick, Riaz J K Khan, Brett W Robertson
BACKGROUND: Dissatisfaction following total knee arthroplasty (TKA) is common. Approximately 20% of patients report dissatisfaction following primary TKA. This systematic literature review explores key factors affecting patient dissatisfaction following TKA. METHODS: Six literature databases published between 2005 and 1 January 2016 were searched using 3 key search phrases. Papers were included if the study investigated patient dissatisfaction in primary unilateral or bilateral TKA...
July 21, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28843585/metallic-coil-and-n-butyl-2-cyanoacrylate-for-closure-of-pancreatic-duct-leak-with-video
#19
Ara B Sahakian, Preeth Jayaram, M Victoria Marx, Kazuhide Matsushima, Caroline Park, James L Buxbaum
BACKGROUND AND AIMS: Pancreatic fistula is a challenging yet common adverse event of partial pancreatectomy. Our objective is to determine the feasibility of endoscopic closure of a pancreatic fistula using a combination of a metallic coil and N-butyl-2-cyanoacrylate (NBCA) glue. METHODS: A patient with a postoperative pancreatic stump leak recalcitrant to conservative management and pancreatic duct stenting underwent endoscopic/fluoroscopic placement of a metallic coil in the pancreatic duct followed by injection of 0...
August 23, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28843396/profiling-gene-expression-of-antimony-response-genes-in-leishmania-viannia-panamensis-and-infected-macrophages-and-its-relationship-with-drug-susceptibility
#20
Maria Claudia Barrera, Laura Jimena Rojas, Austin Weiss, Olga Fernandez, Diane McMahon-Pratt, Nancy G Saravia, Maria Adelaida Gomez
The mechanisms of Leishmania resistance to antimonials have been primarily determined in experimentally derived Leishmania strains. However, their participation in the susceptibility phenotype in field isolates has not been conclusively established. Being an intracellular parasite, the activity of antileishmanials is dependent on internalization of drugs into host cells and effective delivery to the intracellular compartments inhabited by the parasite. In this study we quantified and comparatively analyzed the gene expression of nine molecules involved in mechanisms of xenobiotic detoxification and Leishmania resistance to antimonial drugs in resistant and susceptible laboratory derived and clinical L...
August 24, 2017: Acta Tropica
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