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https://www.readbyqxmd.com/read/29421823/-what-do-we-know-about-osteitis-pubis-in-athletes
#1
Jens Kelm, Oliver Ludwig, Jan André, Stefan Maas, Sascha Hopp
BACKGROUND:  Osteitis pubis is a common cause of chronic groin pain. Due to high clinical uncertainty and varying etiopathology, the diagnosis is often delayed. Especially athletes suffer from this disease, but patients with orthopaedic, traumatological, neurological, urological, gynaecological, and rheumatic complaints can also be affected. Osteitis pubis can be treated by conservative as well as surgical techniques. MATERIAL AND METHODS:  Systematic literature research, descriptive presentation of the studies, and interpretation of evidence-based medicine results...
February 8, 2018: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29400625/undisclosed-conflicts-of-interests-among-biomedical-textbook-authors
#2
Brian J Piper, Drew A Lambert, Ryan C Keefe, Phoebe U Smukler, Nicolas A Selemon, Zachary R Duperry
BACKGROUND: Textbooks are a formative resource for health care providers during their education and are also an enduring reference for pathophysiology and treatment. Unlike the primary literature and clinical guidelines, biomedical textbook authors do not typically disclose potential financial conflicts of interest (pCoI). The objective of this study was to evaluate whether the authors of textbooks used in the training of physicians, pharmacists, and dentists had appreciable undisclosed pCoI in the form of patents or compensation received from pharmaceutical or biotechnology companies...
February 5, 2018: AJOB Empirical Bioethics
https://www.readbyqxmd.com/read/29394413/sleep-disordered-breathing-in-epilepsy-epidemiology-mechanisms-and-treatment
#3
Shobi Sivathamboo, Piero Perucca, Dennis Velakoulis, Nigel C Jones, Jeremy Goldin, Patrick Kwan, Terence J O'Brien
Epilepsy is a group of neurological conditions in which there is a pathological and enduring predisposition to generate recurrent seizures. Evidence over the last few decades suggest that epilepsy may be associated with increased sleep disordered breathing, which may contribute towards sleep fragmentation, daytime somnolence, reduced seizure control, and cardiovascular related morbidity and mortality. Chronic sleep disordered breathing can result in loss of gray matter, and cause deficits to memory and global cognitive function...
January 31, 2018: Sleep
https://www.readbyqxmd.com/read/29355914/intraoperative-imaging-technology-to-maximise-extent-of-resection-for-glioma
#4
REVIEW
Michael D Jenkinson, Damiano Giuseppe Barone, Andrew Bryant, Luke Vale, Helen Bulbeck, Theresa A Lawrie, Michael G Hart, Colin Watts
BACKGROUND: Extent of resection is considered to be a prognostic factor in neuro-oncology. Intraoperative imaging technologies are designed to help achieve this goal. It is not clear whether any of these sometimes very expensive tools (or their combination) should be recommended as standard care for people with brain tumours. We set out to determine if intraoperative imaging technology offers any advantage in terms of extent of resection over standard surgery and if any one technology was more effective than another...
January 22, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29354756/multifocal-intradural-extramedullary-anaplastic-ependymoma-of-the-spine
#5
Ananya Chakravorty, Ellen Frydenberg, Tint Tint Shein, John Ly, Peter Earls, Timothy Steel
Ependymomas are neuroectodermal tumours arising from the ependymal lining of the ventricles and central canal of the spinal cord. Intradural extramedullary (IDEM) ependymomas which are multifocal, and/or anaplastic (WHO grade III) at presentation are exceedingly rare. We present the second case of multifocal anaplastic IDEM ependymoma in the literature. A 47-year old female presented with left gluteal and thigh pain radiating to the groin associated with paraesthesiae. She had a normal neurological examination...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29327099/-genetics-of-tremor
#6
REVIEW
G Kuhlenbäumer, F Hopfner
BACKGROUND: Tremor is a symptom of many diseases and can constitute a disease of its own: essential tremor. OBJECTIVE: The genetics of essential tremor and differential diagnosis of monogenic diseases with the symptom tremor. MATERIAL AND METHODS: Literature search and search of clinical genetics databases, e.g. OMIM, GeneReviews, MDSGene and the German Neurological Society (DGN) guidelines. RESULTS: The genetics of essential tremor remain unresolved in spite of large, adequately powered studies...
January 11, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29324959/surveillance-of-intradomiciliary-contacts-of-leprosy-cases-perspective-of-the-client-in-a-hyperendemic-municipality
#7
Helizandra Simoneti Bianchini Romanholo, Eliana Amorim de Souza, Alberto Novaes Ramos Júnior, Adélia Cileode Gomes Castelo Branco Kaiser, Ismália Oliveira da Silva, Aline Lima Brito, Cídia Vasconcellos
OBJECTIVE: To characterize approach methods for intradomiciliary contacts (IdC) of leprosy cases resident in Northern Brazil, during 2001-2012. METHOD: A cross-sectional and descriptive study in the state of Rondônia. Included IdC of leprosy cases diagnosed/reported in SINAN-Ministry of Health (MS), 2001-2012. A semi-structured instrument was applied to the IdCs, with six interventions: complete dermatological examination; complete neurological examination; BCG vaccination; instructions for return to the health unit; BCG guidance; and guidance to mobilize other contacts...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29324936/the-impact-of-lung-perfusion-scintigraphy-in-the-emergency-management-of-patients-with-suspected-pulmonary-embolism
#8
Cristina Ferrari, Alessandra Cimino, Giacomo Bianco, Francesca Iuele, Alessandra Di Palo, Margherita Fanelli, Artor Niccoli-Asabella, Giuseppe Rubini
OBJECTIVE: Pulmonary Embolism (PE) is an emergency condition that requires immediate treatment. As the symptoms and the risk factors are nonspecific, PE differential diagnosis is often required. Even if angio-CT is considered the gold standard for PE diagnosis, the frequent allergic condition and/or chronic renal failure of patients make, in most cases, not possible the use of contrast enhancement in emergency with even more increasing use of Lung Perfusion Scintigraphy (LPS), as a simple and fast examination with no preparation/contraindication...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29304497/predictors-of-hematological-abnormalities-in-multiple-sclerosis-patients-treated-with-fingolimod-and-dimethyl-fumarate-and-impact-of-treatment-switch-on-lymphocyte-and-leukocyte-count
#9
M Baharnoori, C T Gonzalez, A Chua, C Diaz-Cruz, B C Healy, J Stankiewicz, H L Weiner, T Chitnis
BACKGROUND: There is limited data regarding the predictors of hematological abnormalities in multiple sclerosis (MS) patients treated with dimethyl fumarate (DMF) or fingolimod (FNG), and the impact of treatment switch on lymphocyte and leukocyte count METHODS: We identified 405 patients on DMF and 300 patients on FNG (treatment duration: at least 12 month) within a large prospective study of MS patients conducted at the Partners MS Center, Brigham and Women's Hospital (CLIMB study) between Jan 2011 to Feb 2016...
December 14, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29302622/challenges-in-diagnosing-normal-pressure-hydrocephalus-evaluation-of-the-diagnostic-guidelines
#10
J Andersson, M Rosell, K Kockum, L Söderström, K Laurell
Purpose: To evaluate the present diagnostic guidelines of idiopathic normal pressure hydrocephalus (iNPH) in a sample from the general population. Methods: A total of 168 individuals (93 females, 75 males), mean age 75 years (range 66-92) with and without symptoms of iNPH underwent a CT-scan of the brain, a neurological examination with assessment of the triad symptoms, i.e. gait disturbances, memory impairment and urgency incontinence. The participants were then diagnosed as "unlikely", "possible" and "probable" iNPH according to the American-European and the Japanese guidelines, respectively...
June 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29290375/prediction-of-mri-findings-including-disc-injury-and-posterior-ligamentous-complex-injury-in-neurologically-intact-thoracolumbar-burst-fractures-by-the-parameters-of-vertebral-body-damage-on-ct-scan
#11
Jie Mi, Xiao-Jiang Sun, Kai Zhang, Chang-Qing Zhao, Jie Zhao
OBJECTIVE: To formulate radiological indexes based on CT for further MRI examination to detect posterior ligamentous complex injury (PLC) or disc injury in thoracolumbar burst fractures without neurological deficit in the emergent setting. MATERIALS AND METHODS: Patients with a single thoracolumbar burst fracture and no neurological deficit were included into this study. Radiological indexes on CT included canal compromise (CC), anterior and posterior vertebral height ratio (PVH and AVH ratio), local kyphosis (LK) and regional kyphosis (RK)...
December 15, 2017: Injury
https://www.readbyqxmd.com/read/29285572/characteristics-and-diagnoses-of-acute-headache-in-pregnant-women-a-retrospective-cross-sectional-study
#12
Bianca Raffaelli, Eberhard Siebert, Jeannette Körner, Thomas Liman, Uwe Reuter, Lars Neeb
BACKGROUND: Acute headache is one of the most frequent neurological symptoms in pregnant women. The early diagnosis of underlying secondary conditions has a major influence on patient outcome, especially in emergency settings. However, at the time being no well-established guideline for diagnostic evaluation of acute headache during pregnancy exists. In this study, we aimed to characterize acute headache in pregnant women concerning demographic, clinical, and diagnostic features, and to determine predictors of secondary headache...
December 4, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29280925/ontemporary-utilization-of-resuscitative-thoracotomy-results-from-the-aast-aortic-occlusion-for-resuscitation-in-trauma-and-acute-care-surgery-aorta-multicenter-registry
#13
Joseph DuBose, Timothy Fabian, Tiffany Bee, Laura J Moore, John B Holcomb, Megan Brenner, David Skarupa, Kenji Inaba, Todd E Rasmussen, David Turay, Thomas M Scalea
INTRODUCTION: Several reviews of Resuscitative thoracotomy (RT) use over the last 5 decades have been conducted, most recently the evidence-based practice management guideline (PMG) of the Eastern Association for the Surgery of Trauma (EAST). The present study was designed to examine contemporary RT utilization and outcomes compared to historical data (n = 10,238) from the EAST PMG review from published series 1974 - 2013. METHODS: The AAST AORTA registry was utilized to identify patients undergoing RT in the ED from Nov 2013 to Dec 2016...
December 26, 2017: Shock
https://www.readbyqxmd.com/read/29262441/imaging-in-neurocritical-care-practice
#14
Craig Williamson, Larry Morgan, Joshua P Klein
The use of neuroimaging in conjunction with serial neurological examinations is a core component of modern neurocritical care practice. Although there is a growing role for other neuromonitoring techniques, the ability to quickly and accurately interpret images in the context of a patient's clinical status arguably remains the indispensable skill for neurocritical care practitioners. Due to its rapid acquisition time and excellent ability to detect intracerebral hemorrhage (ICH), cerebral edema, and signs of elevated intracranial pressure, computed tomography (CT) remains the most useful neuroimaging technique for intensive care unit (ICU) patients...
December 2017: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29241628/-care-of-the-newborn-with-perinatal-asphyxia-candidate-for-therapeutic-hypothermia-during-the-first-six-hours-of-life-in-spain
#15
Juan Arnaez, Alfredo Garcia-Alix, Sara Calvo, Simón Lubián-López
INTRODUCTION: The process of care and assistance from birth to the starting of therapeutic hypothermia (TH) is crucial in order to improve its effectiveness and prevent the worsening of hypoxic-ischaemic injury. METHODS: A national cross-sectional study carried out in 2015 by use of a questionnaire sent to all level iii units on the care of the newborn≥35 weeks gestation within the first hours of life after a perinatal asphyxia event. According to clinical practice guidelines, the quality of care was compared between the hospitals that carried out or did not carry out TH, and according to the level of care...
December 11, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29229178/cervical-spine-clearance-in-adults-following-blunt-trauma-a-national-survey-across-major-trauma-centres-in-england
#16
G Chilvers, K Porter, S Choudhary
AIM: To assess current practice in cervical spine clearance across major trauma centres in England and review current guidelines. MATERIALS AND METHODS: An electronic survey was sent to lead trauma clinicians at 22 major trauma centres in England. This assessed the clinical decision tools used, the choice of initial imaging technique, and the methods used to clear the cervical spine in alert and obtunded patients without focal neurology, and where initial imaging was normal...
December 8, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29218822/european-academy-of-neurology-european-stroke-organisation-consensus-statement-and-practical-guidance-for-pre-hospital-management-of-stroke
#17
A Kobayashi, A Czlonkowska, G A Ford, A C Fonseca, G J Luijckx, J Korv, N Pérez de la Ossa, C Price, D Russell, A Tsiskaridze, M Messmer-Wullen, J De Keyser
Reduction of delay between onset and hospital arrival and adequate pre-hospital care of persons with acute stroke are important for improving chances of a favorable outcome. The objective is to recommend evidence-based practices for the management of patients with suspected stroke in the pre-hospital setting. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology was used to define the key clinical questions. An expert panel then reviewed the literature, established the quality of the evidence, and made recommendations...
December 7, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29214153/alzheimer-s-disease-diagnosis-discrepancy-between-clinical-neuroimaging-and-cerebrospinal-fluid-biomarkers-criteria-in-an-italian-cohort-of-geriatric-outpatients-a-retrospective-cross-sectional-study
#18
Giulia A M Dolci, Sarah Damanti, Valeria Scortichini, Alessandro Galli, Paolo D Rossi, Carlo Abbate, Beatrice Arosio, Daniela Mari, Andrea Arighi, Giorgio G Fumagalli, Elio Scarpini, Silvia Inglese, Maura Marcucci
Background: The role of cerebrospinal fluid (CSF) biomarkers, and neuroimaging in the diagnostic process of Alzheimer's disease (AD) is not clear, in particular in the older patients. Objective: The aim of this study was to compare the clinical diagnosis of AD with CSF biomarkers and with cerebrovascular damage at neuroimaging in a cohort of geriatric patients. Methods: Retrospective analysis of medical records of ≥65-year-old patients with cognitive impairment referred to an Italian geriatric outpatient clinic, for whom the CSF concentration of amyloid-β (Aβ), total Tau (Tau), and phosphorylated Tau (p-Tau) was available...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29207432/-sonography-of-the-optic-nerve-a-new-bedside-tool-in-intensive-care
#19
Christopher Hohmann, Konrad R Koch, Roman Pfister, Guido Michels
History and clinical findings Here, we present the case history of a 76-year old man with out-of-hospital cardiac arrest due to a cardiogenic shock and a consecutive no-flow-time of approximately 10 minutes. After 25 minutes of resuscitation procedures a spontaneous return of circulation could be established. The patient was admitted to our center for emergency coronary angiography. After coronary stenting the patient was admitted to our intensive care unit and treated in accordance with the guidelines on cardiogenic shock due to myocardial infarction...
December 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29189108/return-to-work-after-young-stroke-a-systematic-review
#20
Jodi D Edwards, Arunima Kapoor, Elizabeth Linkewich, Richard H Swartz
Background The incidence of stroke in young adults is increasing. While many young survivors are able to achieve a good physical recovery, subtle dysfunction in other domains, such as cognition, often persists, and could affect return to work. However, reported estimates of return to work and factors affecting vocational outcome post-stroke vary greatly. Aims The aims of this systematic review were to determine the frequency of return to work at different time points after stroke and identify predictors of return to work...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
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