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https://www.readbyqxmd.com/read/28339428/does-conservative-treatment-change-the-brain-in-patients-with-chronic-musculoskeletal-pain-a-systematic-review
#1
Jeroen Kregel, Iris Coppieters, Robby DePauw, Anneleen Malfliet, Lieven Danneels, Jo Nijs, Barbara Cagnie, Mira Meeus
BACKGROUND: Chronic musculoskeletal pain is characterized by maladaptive central neuroplastic changes. Many observational studies have demonstrated that chronic pain states are associated with brain alterations regarding structure and/or function. Rehabilitation of patients with chronic musculoskeletal pain may include cognitive, exercise, or multimodal therapies. OBJECTIVE: The current review aims to provide a constructive overview of the existing literature reporting neural correlates, based on brain magnetic resonance imaging (MRI) techniques, following conservative treatment in chronic musculoskeletal pain patients...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28332016/radiology-research-in-mainland-china-in-the-past-10-years-a-survey-of-original-articles-published-in-radiology-and-european-radiology
#2
Long Jiang Zhang, Yun Fei Wang, Zhen Lu Yang, U Joseph Schoepf, Jiaqian Xu, Guang Ming Lu, Enzhong Li
PURPOSE: To evaluate the features and trends of Radiology research in Mainland China through bibliometric analysis of the original articles published in Radiology and European Radiology (ER) between 2006 and 2015. MATERIALS AND METHODS: We reviewed the original articles published in Radiology and ER between 2006 and 2015. The following information was abstracted: imaging subspecialty, imaging technique(s) used, research type, sample size, study design, statistical analysis, study results, funding declarations, international collaborations, number of authors, department and province of the first author...
March 22, 2017: European Radiology
https://www.readbyqxmd.com/read/28329785/beet-root-juice-an-ergogenic-aid-for-exercise-and-the-aging-brain
#3
Meredith Petrie, W Jack Rejeski, Swati Basu, Paul J Laurienti, Anthony P Marsh, James L Norris, Daniel B Kim-Shapiro, Jonathan H Burdette
Background: Exercise has positive neuroplastic effects on the aging brain. It has also been shown that ingestion of beet root juice (BRJ) increases blood flow to the brain and enhances exercise performance. Here, we examined whether there are synergistic effects of BRJ and exercise on neuroplasticity in the aging brain. Methods: Peak metabolic equivalent (MET) capacity and resting-state magnetic resonance imaging functional brain network organization are reported on 26 older (mean age = 65...
November 9, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28328692/experience-with-a-care-process-model-in-the-evaluation-of-pediatric-musculoskeletal-infections-in-a-pediatric-emergency-department
#4
Lina Patel, Jeff Michael, Nancy Allen, Lisa Schroeder, Lisa Berglund, Jason G Newland
OBJECTIVES: Care process models (CPMs) for certain conditions have improved clinical outcomes in children. This study describes the implementation and impact of a CPM for the evaluation of musculoskeletal infections in a pediatric emergency department (ED). METHODS: A retrospective pre-post intervention study was performed to analyze the impact of a musculoskeletal infection CPM. Patients were identified retrospectively through electronic order history for imaging of an extremity or joint and recommended laboratory tests...
March 21, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28328579/resting-state-functional-connectivity-predicts-longitudinal-pain-symptom-change-in-urologic-chronic-pelvic-pain-syndrome-a-mapp-network-study
#5
Jason J Kutch, Jennifer S Labus, Richard E Harris, Katherine T Martucci, Melissa A Farmer, Sonja Fenske, Connor Fling, Eric Ichesco, Scott Peltier, Bogdan Petre, Wensheng Guo, Xiaoling Hou, Alisa J Stephens, Chris Mullins, Daniel J Clauw, Sean C Mackey, A Vania Apkarian, J Richard Landis, Emeran A Mayer
Chronic pain symptoms often change over time, even in individuals who have had symptoms for years. Studying biological factors that predict trends in symptom change in chronic pain may uncover novel pathophysiological mechanisms and potential therapeutic targets. In this study, we investigated whether brain functional connectivity measures obtained from resting-state functional MRI (rs-fMRI) at baseline can predict longitudinal symptom change (3, 6, and 12 months post-scan) in urologic chronic pelvic pain syndrome (UCPPS)...
March 17, 2017: Pain
https://www.readbyqxmd.com/read/28327114/study-protocol-for-a-randomized-controlled-trial-comparing-clinical-and-radiological-results-after-three-different-posterior-decompression-techniques-for-lumbar-spinal-stenosis-the-spinal-stenosis-trial-sst-part-of-the-nordsten-study
#6
Erland Hermansen, Ivar Magne Austevoll, Ulla Kristina Romild, Frode Rekeland, Tore Solberg, Kjersti Storheim, Oliver Grundnes, Jørn Aaen, Jens Ivar Brox, Christian Hellum, Kari Indrekvam
BACKGROUND: There are several posterior decompression techniques for lumbar spinal stenosis (LSS). There is a trend towards performing less invasive surgical procedures, but no multicentre randomized controlled trials have evaluated the relative efficacy of these techniques at short and long-term. METHOD/DESIGN: A multicentre randomized controlled trial [the Spinal Stenosis Trial (SST) (part of the NORDSTEN study)] including 465 patients aged 18-80 years with neurogenic claudication or radiating pain and MRI findings indicating lumbar spinal stenosis without spondylolisthesis is performed to compare three posterior decompression techniques: unilateral laminotomy with crossover, bilateral laminotomy and spinous process osteotomy...
March 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28325486/mri-utilization-and-the-associated-use-of-sedation-and-anesthesia-in-a-pediatric-aco
#7
Joshua C Uffman, Dmitry Tumin, Vidya Raman, Arlyne Thung, Brent Adler, Joseph D Tobias
BACKGROUND AND OBJECTIVES: MRI is commonly used in the pediatric population and often requires sedation or general anesthesia to complete. This study used data from a pediatric accountable care organization (ACO) to investigate trends in MRI utilization and in the requirement for anesthesia to complete MRI examinations. METHODS: The Partners for Kids (PFK) ACO claims database was queried for MRI examination encounters involving patients 0 to 18 years old from 2009 to 2014, with utilization expressed as encounters per 10,000 PFK members-months...
March 15, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28323582/white-matter-integrity-in-high-altitude-pilots-exposed-to-hypobaria
#8
Stephen A McGuire, Goldie R E Boone, Paul M Sherman, David F Tate, Joe D Wood, Beenish Patel, George Eskandar, S Andrea Wijtenburg, Laura M Rowland, Geoffrey D Clarke, Patrick M Grogan, John H Sladky, Peter V Kochunov
INTRODUCTION: Nonhypoxic hypobaric (low atmospheric pressure) occupational exposure, such as experienced by U.S. Air Force U-2 pilots and safety personnel operating inside altitude chambers, is associated with increased subcortical white matter hyperintensity (WMH) burden. The pathophysiological mechanisms underlying this discrete WMH change remain unknown. The objectives of this study were to demonstrate that occupational exposure to nonhypoxic hypobaria is associated with altered white matter integrity as quantified by fractional anisotropy (FA) measured using diffusion tensor imaging and relate these findings to WMH burden and neurocognitive ability...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28323572/bilateral-changes-in-deep-tissue-environment-after-manual-lymphatic-drainage-in-patients-with-breast-cancer-treatment-related-lymphedema
#9
Paula M C Donahue, Rachelle Crescenzi, Allison O Scott, Vaughn Braxton, Aditi Desai, Seth A Smith, John Jordi, Ingrid M Meszoely, Ana M Grau, Rondi M Kauffmann, Raeshell S Sweeting, Kandace Spotanski, Sheila H Ridner, Manus J Donahue
BACKGROUND: Breast cancer treatment-related lymphedema (BCRL) arises from a mechanical insufficiency following cancer therapies. Early BCRL detection and personalized intervention require an improved understanding of the physiological processes that initiate lymphatic impairment. Here, internal magnetic resonance imaging (MRI) measures of the tissue microenvironment were paired with clinical measures of tissue structure to test fundamental hypotheses regarding structural tissue and muscle changes after the commonly used therapeutic intervention of manual lymphatic drainage (MLD)...
March 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28317892/ultra-wide-range-field-dependent-measurements-of-the-relaxivity-of-gd1-xeuxvo4-nanoparticle-contrast-agents-using-a-mechanical-sample-shuttling-relaxometer
#10
Ching-Yu Chou, Mouna Abdesselem, Cedric Bouzigues, Minglee Chu, Angelo Guiga, Tai-Huang Huang, Fabien Ferrage, Thierry Gacoin, Antigoni Alexandrou, Dimitris Sakellariou
The current trend for Magnetic Resonance Imaging points towards higher magnetic fields. Even though sensitivity and resolution are increased in stronger fields, T1 contrast is often reduced, and this represents a challenge for contrast agent design. Field-dependent measurements of relaxivity are thus important to characterize contrast agents. At present, the field-dependent curves of relaxivity are usually carried out in the field range of 0 T to 2 T, using fast field cycling relaxometers. Here, we employ a high-speed sample shuttling device to switch the magnetic fields experienced by the nuclei between virtually zero field, and the center of any commercial spectrometer...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28315932/body-and-liver-fat-content-and-adipokines-in-schizophrenia-a-magnetic-resonance-imaging-and-spectroscopy-study
#11
Jong-Hoon Kim, Jung-Hyun Kim, Pil-Whan Park, Jürgen Machann, Michael Roden, Sheen-Woo Lee, Jong-Hee Hwang
RATIONALE: Although antipsychotic treatment often causes weight gain and lipid abnormalities, quantitative analyses of tissue-specific body fat content and its distribution along with adipokines have not been reported for antipsychotic-treated patients. OBJECTIVES: The purposes of the present study were to quantitatively assess abdominal and liver fat in patients with schizophrenia on antipsychotic treatment and age- and body mass index (BMI)-matched healthy controls and to evaluate their associations with plasma leptin and adiponectin levels...
March 18, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28303489/in-vivo-dce-mri-for-the-discrimination-between-glioblastoma-and-radiation-necrosis-in-rats
#12
Julie Bolcaen, Benedicte Descamps, Marjan Acou, Karel Deblaere, Caroline Van den Broecke, Tom Boterberg, Christian Vanhove, Ingeborg Goethals
PURPOSE: In this study, the potential of semiquantitative and quantitative analysis of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) was investigated to differentiate glioblastoma (GB) from radiation necrosis (RN) in rats. PROCEDURES: F98 GB growth was seen on MRI 8-23 days post-inoculation (n = 15). RN lesions developed 6-8 months post-irradiation (n = 10). DCE-MRI was acquired using a fast low-angle shot (FLASH) sequence. Regions of interest (ROIs) encompassed peripheral contrast enhancement in GB (n = 15) and RN (n = 10) as well as central necrosis within these lesions (GB (n = 4), RN (n = 3))...
March 16, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28299592/the-effect-of-a-celebrity-health-disclosure-on-demand-for-health-care-trends-in-brca-testing-and-subsequent-health-services-use
#13
Megan C Roberts, Stacie B Dusetzina
In May 2013, an internationally renowned celebrity-Angelina Jolie-disclosed her receipt of BRCA1/BRCA2 (BRCA) testing and subsequent double mastectomy in a highly publicized editorial. Publicity surrounding celebrity health services use increases awareness of important health issues and demand for health services. We aimed to describe BRCA testing trends before and after Jolie's disclosure, breast cancer-related services use following testing, and test reimbursement trends. MarketScan Commercial Claims data were used to compare trends in BRCA testing before and after Jolie's health disclosure using an interrupted time series model among women aged 18-64...
March 15, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28298968/feasibility-of-imaging-superficial-palmar-arch-using-micro-ultrasound-7t-and-3t-magnetic-resonance-imaging
#14
Alison N Pruzan, Audrey E Kaufman, Claudia Calcagno, Yu Zhou, Zahi A Fayad, Venkatesh Mani
AIM: To demonstrate feasibility of vessel wall imaging of the superficial palmar arch using high frequency micro-ultrasound, 7T and 3T magnetic resonance imaging (MRI). METHODS: Four subjects (ages 22-50 years) were scanned on a micro-ultrasound system with a 45-MHz transducer (Vevo 2100, VisualSonics). Subjects' hands were then imaged on a 3T clinical MR scanner (Siemens Biograph MMR) using an 8-channel special purpose phased array carotid coil. Lastly, subjects' hands were imaged on a 7T clinical MR scanner (Siemens Magnetom 7T Whole Body Scanner) using a custom built 8-channel transmit receive carotid coil...
February 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28298728/modified-approach-to-the-characterization-of-adrenal-nodules-using-a-standard-abdominal-magnetic-resonance-imaging-protocol
#15
António P Matos, Richard C Semelka, Vasco Herédia, Mamdoh AlObaidiy, Filipe Veloso Gomes, Miguel Ramalho
OBJECTIVE: To describe a modified approach to the evaluation of adrenal nodules using a standard abdominal magnetic resonance imaging protocol. MATERIALS AND METHODS: Our sample comprised 149 subjects (collectively presenting with 132 adenomas and 40 nonadenomas). The adrenal signal intensity index was calculated. Lesions were grouped by pattern of enhancement (PE), according to the phase during which the wash-in peaked: arterial phase (type 1 PE); portal venous phase (type 2 PE); and interstitial phase (type 3 PE)...
January 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28294459/identifying-dynamic-functional-connectivity-biomarkers-using-gig-ica-application-to-schizophrenia-schizoaffective-disorder-and-psychotic-bipolar-disorder
#16
Yuhui Du, Godfrey D Pearlson, Dongdong Lin, Jing Sui, Jiayu Chen, Mustafa Salman, Carol A Tamminga, Elena I Ivleva, John A Sweeney, Matcheri S Keshavan, Brett A Clementz, Juan Bustillo, Vince D Calhoun
Functional magnetic resonance imaging (fMRI) studies have shown altered brain dynamic functional connectivity (DFC) in mental disorders. Here, we aim to explore DFC across a spectrum of symptomatically-related disorders including bipolar disorder with psychosis (BPP), schizoaffective disorder (SAD), and schizophrenia (SZ). We introduce a group information guided independent component analysis procedure to estimate both group-level and subject-specific connectivity states from DFC. Using resting-state fMRI data of 238 healthy controls (HCs), 140 BPP, 132 SAD, and 113 SZ patients, we identified measures differentiating groups from the whole-brain DFC and traditional static functional connectivity (SFC), separately...
March 10, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28289373/reentrant-information-flow-in-electrophysiological-rat-default-mode-network
#17
Wei Jing, Daqing Guo, Yunxiang Zhang, Fengru Guo, Pedro A Valdés-Sosa, Yang Xia, Dezhong Yao
Functional MRI (fMRI) studies have demonstrated that the rodent brain shows a default mode network (DMN) activity similar to that in humans, offering a potential preclinical model both for physiological and pathophysiological studies. However, the neuronal mechanism underlying rodent DMN remains poorly understood. Here, we used electrophysiological data to analyze the power spectrum and estimate the directed phase transfer entropy (dPTE) within rat DMN across three vigilance states: wakeful rest (WR), slow-wave sleep (SWS), and rapid-eye-movement sleep (REMS)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28287953/quantitative-comparison-of-spherical-deconvolution-approaches-to-resolve-complex-fiber-configurations-in-diffusion-mri-isra-based-vs-l2l0-sparse-methods
#18
Alfonso Mastropietro, Paola Scifo, Giovanna Rizzo
OBJECTIVE: To quantitatively compare different Spherical Deconvolution (SD) approaches (ISRA-based and sparse L2L0 algorithms) to resolve crossing fiber in diffusion MRI. The purpose of this comparison is to address the area of application in which each approach could better perform. METHODS: ISRA-based (Richardson-Lucy (RL), damped-RL) and sparse L2L0 algorithms were implemented and evaluated on both simulated data and in vivo datasets. Simulations were performed at different crossing angles (30° to 90°), b-values (1000 to 3000 s/mm (2) ), SNR (10 to 30), number of fibers (1 to 3)...
March 6, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28284776/neural-underpinnings-of-prosexual-effects-induced-by-gamma-hydroxybutyrate-in-healthy-male-humans
#19
Oliver G Bosch, Michael M Havranek, Andrea Baumberger, Katrin H Preller, Robin von Rotz, Marcus Herdener, Rainer Kraehenmann, Philipp Staempfli, Milan Scheidegger, Tim Klucken, Erich Seifritz, Boris B Quednow
Gamma-hydroxybutyrate (GHB) is a GHB-/GABAB-receptor agonist currently used as treatment for narcolepsy but also as a drug of abuse. Non-medical GHB users have repeatedly reported prosexual effects including libido-enhancement and lowering of attractiveness standards for partner selection. Here, we examined the putative prosexual effects of oral GHB in healthy males in two experiments both employing randomized, placebo-controlled, double-blind, balanced, and cross-over study designs. In experiment I, subjective effects of 20 and 35mg/kg GHB vs...
March 8, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28281277/study-of-normal-volumetric-variation-in-the-putamen-with-age-and-gender-using-magnetic-resonance-imaging
#20
Sujay Halkur Shankar, Sandeep Ballal, Shubha R
INTRODUCTION: Putamen volume is seen to alter in neurological and psychiatric disorders such as Parkinson's disease, depression, schizophrenia, Alzheimer's disease and in patients treated with antipsychotics. To establish a trend in volume changes in pathologic states, studies on factors influencing normal variation in a given population become essential. This study aimed to evaluate the normal variations in putamen volume in the Indian population and correlate them with the effects of age and sex...
March 9, 2017: Clinical Anatomy
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