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Vaccine AND side effects

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https://www.readbyqxmd.com/read/29138660/use-of-cellular-phone-contacts-to-increase-return-rates-for-immunization-services-in-kenya
#1
Evans Mokaya, Isaac Mugoya, Jane Raburu, Lora Shimp
Introduction: In Kenya, failure to complete immunization schedules by children who previously accessed immunization services is an obstacle to ensuring that children are fully immunized. Home visit approaches used to track defaulting children have not been successful in reducing the drop-out rate. Methods: This study tested the use of phone contacts as an approach for tracking immunization defaulters in twelve purposively-selected facilities in three districts of western Kenya...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29129402/hepatitis-b-core-antigen-based-novel-vaccine-against-porcine-epidemic-diarrhea-virus
#2
Frank Gillam, Jianqiang Zhang, Chenming Zhang
Porcine epidemic diarrhea Virus (PEDV) is the causative agent of porcine epidemic diarrhea, which is a devastating viral disease and causes severe economic loss to the swine industry. Current vaccine options for PEDV include modified live viruses and killed live viruses. Though these vaccines have shown efficacy, some have side effects including viral shedding. This report details an E. coli based expression and purification process of multiple vaccine candidates for PEDV using Hepatitis B Core Antigen (HBcAg) as a backbone protein...
November 9, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/29128384/adverse-effects-of-single-component-measles-vaccine-in-school-children
#3
Selam Tosun, Ali Ilgın Olut, Nermin Tansug
Measles is a highly contagious viral infection potentially with serious complications and the principal method of protection from the disease is vaccination. Measles vaccination resulted in a 79% drop in measles deaths between 2000 and 2015 worldwide. There has long been a debate about the necessity and benefit-loss ratio of routine MMR vaccination due to possible AE of MMR vaccine. Especially in developed countries which are thought to be free of measles there is an increasing tendency towards hesitation for vaccination though there have been continued outbreaks of measles in countries in which measles is considered to be eliminated...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29128382/bad-news-the-influence-of-news-coverage-and-google-searches-on-gardasil-adverse-event-reporting
#4
Kate Faasse, Jarry T Porsius, Jonathan Faasse, Leslie R Martin
BACKGROUND: Human papilloma virus vaccines are a safe and effective tool for reducing HPV infections that can cause cervical cancer. However, uptake of these vaccines has been suboptimal, with many people holding negative beliefs and misconceptions. Such beliefs have been linked with the experience of unpleasant side effects following medical treatment, and media coverage may heighten such concerns. METHODS: The present study sought to assess the influence of news coverage (number of news articles per month) on adverse event reporting in response to Gardasil vaccination in New Zealand over a 7...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29126805/determinants-of-influenza-vaccination-among-high-risk-black-and-white-adults
#5
Sandra Crouse Quinn, Amelia M Jamison, Vicki S Freimuth, Ji An, Gregory R Hancock
BACKGROUND: Adults with chronic conditions are at much greater risk of influenza-related morbidity and mortality, yet flu vaccine uptake remains suboptimal. Research focused on the high-risk population has been limited, particularly related to racial disparities in vaccination. We explore a broad range of demographic, racial, and psychosocial factors to identify predictors of vaccination among high-risk adults, with a focus on identify differences between Black and White adults. METHODS: We conducted an online survey in March 2015, utilizing international research firm GfK's KnowledgePanel, for a nationally representative sample of Black and White adults (≥18, USA) and limited analysis adults with high-risk of influenza-related complications...
November 7, 2017: Vaccine
https://www.readbyqxmd.com/read/29115958/to-vaccinate-or-not-to-vaccinate-perspectives-on-hpv-vaccination-among-girls-boys-and-parents-in-the-netherlands-a-q-methodological-study
#6
Nathalie J S Patty, Hanna Maria van Dijk, Iris Wallenburg, Roland Bal, Theo J M Helmerhorst, Job van Exel, Jane Murray Cramm
BACKGROUND: Despite the introduction of Human papillomavirus (HPV) vaccination in national immunization programs (NIPs), vaccination rates in most countries remain relatively low. An understanding of the reasons underlying decisions about whether to vaccinate is essential in order to promote wider spread of HPV vaccination. This is particularly important in relation to policies seeking to address shortfalls in current HPV campaigns. The aim of this study was to explore prevailing perspectives concerning HPV vaccination among girls, boys, and parents, and so to identify potential determinants of HPV vaccination decisions in these groups...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29110528/parental-conceptions-of-the-rotavirus-vaccine-during-implementation-in-stockholm-a-phenomenographic-study
#7
Eva Sjögren, Lina Schollin Ask, Åke Örtqvist, Margareta Asp
In 2014, Stockholm became the first Swedish county to introduce the rotavirus vaccine, which is given from as early as six weeks of age. The aim of this study was to describe parental conceptions of rotavirus infection and vaccination during its implementation as part of the child immunization program, as their support is vital for any new vaccine. The study followed a descriptive, qualitative design with a phenomenographic approach. Ten in-depth interviews with parents were conducted in Stockholm County, transcribed and analyzed to describe qualitatively different conceptions of rotavirus infection and vaccination...
January 1, 2017: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29110027/human-papillomavirus-vaccine-uptake-in-adolescence-and-adherence-to-cervical-cancer-screening-in-switzerland-a-national-cross-sectional-survey
#8
Monica N Wymann, Anne Spaar Zographos, Ekkehardt Altpeter, Virginie Masserey Spicher, Nicola Low, Mirjam Mäusezahl-Feuz
OBJECTIVES: The objectives were to measure uptake of and factors associated with human papillomavirus (HPV) vaccination initiation and to determine whether HPV vaccination reduced the uptake of cervical cancer screening. METHODS: We conducted a cross-sectional survey in a random sample of Swiss women aged 18-49 years in 2014 (N = 3588). RESULTS: Vaccination initiation was 69.3% and full coverage (three doses) 54.1% for 18-20-year olds, respectively, 42...
November 6, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/29109964/immunotherapy-as-a-promising-treatment-for-prostate-cancer-a-systematic-review
#9
REVIEW
Marlena Janiczek, Łukasz Szylberg, Anna Kasperska, Adam Kowalewski, Martyna Parol, Paulina Antosik, Barbara Radecka, Andrzej Marszałek
Prostate cancer treatment is currently based on surgical removal, radiotherapy, and hormone therapy. In recent years, another therapeutic method has emerged-immunological treatment. Immunotherapy modulates and strengthens one's immune responses against cancer. Neoplastic cells naturally escape from the control of the immune system, and the main goal of immune therapy is to bring the control back. Satisfying outcomes after treatment of advanced melanoma and lung cancer suggest a great potential of immunotherapy as an approach for other tumors' treatment, especially in patients primarily introduced to palliative care...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/29109372/marine-algae-as-source-of-novel-antileishmanial-drugs-a-review
#10
REVIEW
Lauve Rachel Tchokouaha Yamthe, Regina Appiah-Opong, Patrick Valere Tsouh Fokou, Nole Tsabang, Fabrice Fekam Boyom, Alexander Kwadwo Nyarko, Michael David Wilson
Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the Leishmania genus and transmitted by the female Phlebotomus and Lutzomyia sand flies. The currently prescribed therapies still rely on pentavalent antimonials, pentamidine, paromomycin, liposomal amphotericin B, and miltefosine. However, their low efficacy, long-course treatment regimen, high toxicity, adverse side effects, induction of parasite resistance and high cost require the need for better drugs given that antileishmanial vaccines may not be available in the near future...
October 29, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29104773/antitumor-vaccines-based-on-dendritic-cells-from-experiments-using-animal-tumor-models-to-clinical-trials
#11
O V Markov, N L Mironova, V V Vlassov, M A Zenkova
The routine methods used to treat oncological diseases have a number of drawbacks, including non-specific action and severe side effects for patients. Furthermore, tumor diseases are associated with a suppression of the immune system that often leads to the inefficiency of standard treatment methods. The development of novel immunotherapeutic approaches having specific antitumor action and that activate the immune system is of crucial importance. Vaccines based on dendritic cells (DCs) loaded with tumor antigens ex vivo that can activate antitumor cytotoxic T-cell responses stand out among different antitumor immunotherapeutic approaches...
July 2017: Acta Naturae
https://www.readbyqxmd.com/read/29104760/noninvasive-vaccination-as-a-casus-belli-to-redeem-vaccine-value-in-the-face-of-anti-vaccine-movements
#12
De-Chu C Tang
Formidable anti-vaccine movements have been growing as a menace to disrupt beneficial vaccine programs. Although the vaccination-associated adverse effects commonly perceived by vaccine resisters usually represent over-reactions to rare manifestations, converging evidence shows that vaccination-associated health threats could be pervasive when systemic inflammation is considered as a side effect that oozes over time. An anti-vaccine movement thus may not be so unfounded even though the myriad cascades triggered by systemic inflammation have not been brought to a clear focus during any anti-vaccine campaign...
2017: Integrative Molecular Medicine
https://www.readbyqxmd.com/read/29081071/herpes-zoster-meningitis-in-immunocompetent-children-two-case-reports-and-a-literature-review
#13
Naohiro Itoh, Kouji Motokura, Akira Kumakura, Daisuke Hata, Atsuko Hata
We encountered two cases of Herpes zoster (HZ) meningitis, a rarely occurring complication of HZ, in previously healthy children. One patient treated with i.v. acyclovir (ACV, 31 mg/kg/day) did not recover. His symptoms were relieved somewhat by increased ACV dosage, but it caused transient renal dysfunction. Another patient treated with i.v. ACV (30 mg/kg/day) recovered. Treatment for HZ meningitis in immunocompetent children has not been established. In a literature review, 80% of 20 patients were treated with the usual dose of ACV 15-30 mg/kg/day...
October 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29076688/herpes-zoster-during-immunosuppressive-therapy-for-autoimmune-diseases
#14
Mohammad Faizan Zahid, Mariam Ghufran, Armaghan-E-Rehman Mansoor, Muhammad Rizwan Sohail
BACKGROUND: Patients on immunosuppressive therapy are at a greater risk for herpes zoster reactivation and are more likely to have adverse outcomes. Propylactic antivrials and vaccinations may potentially prevent these complications. METHODS: Medical literature addressing the clinical course and therapy of herpes zoster in patients receiving immunosuppressive therapy for autoimmune disorders, and the roles of anti-viral prophylaxis and vaccination was reviewed. Research databases including PubMed, Ovid, Medline, Google Scholar and Cochrane were utilized...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29074178/factors-affecting-hpv-vaccine-acceptance-in-west-austria-do-we-need-to-revise-the-current-immunization-scheme
#15
Wegene Borena, Anita Luckner-Hornischer, Franz Katzgraber, Dorothee Holm-von Laer
BACKGROUND: Austria introduced a school-based gender-neutral human papillomavirus (HPV) immunization program in February 2014. In order to assure high coverage, factors influencing acceptance of the vaccine need to be identified. In this study we aim to assess parents' attitude and related socio-demographic factors in relation to the newly implemented gender-neutral, school-based HPV Immunization program. METHODS: Parents of 4th grade school children in 20 randomly selected primary schools were asked to fill out questionnaires on socio-demographic factors and on the level of information and attitude towards HPV infection and HPV vaccine...
December 2016: Papillomavirus Research
https://www.readbyqxmd.com/read/29069089/an-%C3%AE-gal-containing-neoglycoprotein-based-vaccine-partially-protects-against-murine-cutaneous-leishmaniasis-caused-by-leishmania-major
#16
Eva Iniguez, Nathaniel S Schocker, Krishanthi Subramaniam, Susana Portillo, Alba L Montoya, Waleed S Al-Salem, Caresse L Torres, Felipe Rodriguez, Otacilio C Moreira, Alvaro Acosta-Serrano, Katja Michael, Igor C Almeida, Rosa A Maldonado
BACKGROUND: Protozoan parasites from the genus Leishmania cause broad clinical manifestations known as leishmaniases, which affect millions of people worldwide. Cutaneous leishmaniasis (CL), caused by L. major, is one the most common forms of the disease in the Old World. There is no preventive or therapeutic human vaccine available for L. major CL, and existing drug treatments are expensive, have toxic side effects, and resistant parasite strains have been reported. Hence, further therapeutic interventions against the disease are necessary...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29062681/factors-associated-with-the-human-papillomavirus-hpv-vaccination-across-three-countries-following-vaccination-introduction
#17
Brooke Nickel, Rachael H Dodd, Robin M Turner, Jo Waller, Laura Marlow, Gregory Zimet, Remo Ostini, Kirsten McCaffery
Direct international comparisons which aim to understand how factors associated with human papillomavirus (HPV) vaccine initiation and attitudes towards the HPV vaccination in parents differ are scarce. Parents (n = 179) of daughters aged 9-17 years in the US, UK and Australia completed an online survey in 2011 with questions measuring daughters' HPV vaccination status, HPV knowledge, HPV vaccination knowledge, and statements assessing attitude towards the HPV vaccine. The strongest factor associated with vaccination status across all countries was parental HPV knowledge (p < 0...
December 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29059230/a-structural-explanation-for-the-low-effectiveness-of-the-seasonal-influenza-h3n2-vaccine
#18
Nicholas C Wu, Seth J Zost, Andrew J Thompson, David Oyen, Corwin M Nycholat, Ryan McBride, James C Paulson, Scott E Hensley, Ian A Wilson
The effectiveness of the annual influenza vaccine has declined in recent years, especially for the H3N2 component, and is a concern for global public health. A major cause for this lack in effectiveness has been attributed to the egg-based vaccine production process. Substitutions on the hemagglutinin glycoprotein (HA) often arise during virus passaging that change its antigenicity and hence vaccine effectiveness. Here, we characterize the effect of a prevalent substitution, L194P, in egg-passaged H3N2 viruses...
October 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29053369/effects-of-message-framing-on-influenza-vaccination-understanding-the-role-of-risk-disclosure-perceived-vaccine-efficacy-and-felt-ambivalence
#19
Sungsu Kim, Ivanka Pjesivac, Yan Jin
The current study examined the effects of framing in promotional health messages on intention to vaccinate against seasonal influenza virus. The findings of an experimental study (N = 86) indicated that exposure to both benefits and side effects of vaccination (gain-framed with risk disclosure message) led to lower intention to receive the flu vaccine. This relationship was mediated by both perceived vaccine efficacy and felt ambivalence in a serial order, revealing the underlying psychological mechanisms important for understanding health-related behaviors...
October 20, 2017: Health Communication
https://www.readbyqxmd.com/read/29050417/influence-of-swimming-time-in-alleviating-the-deleterious-effects-of-hot-summer-on-growing-muscovy-duck-performance
#20
Mohamed F A Farghly, Khalid M Mahrose, Zafar Ullah, Zaib Ur Rehman, Chan Ding
This experiment was conducted to observe the effects of varying swimming times (ST) of Muscovy ducks, raised in an open-sided house, in alleviating the deleterious effects of high temperature in hotter times of the day in the summer season on growth performance (body weight, average daily gain, feed consumption, and feed conversion ratio), carcass characteristics, body temperature, and some health aspects. We hypothesized that swimming times during the hottest periods of the day would show different performances...
September 1, 2017: Poultry Science
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