Hao Jiang, Kunqian He, Jie Tan, Ding Zhu, Nan Yang, Yuanyuan Wang, Junbo Zhang, Xinying Li, Yuan Ren, Yuangang Lu
BACKGROUND: Dermatofibrosarcoma Protuberans (DFSP) is a rare, low-grade malignant tumor of the dermis with a high recurrence rate post-surgery. Current treatments, including surgery, radiotherapy, and targeted therapy, have limitations. Photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) is a promising non-invasive approach, but its efficacy in DFSP treatment remains underexplored. METHODS: This study aimed to evaluate the anti-tumor efficacy of 5-ALA PDT using an in vitro model derived from a recurrent DFSP patient...
April 17, 2024: Photodiagnosis and Photodynamic Therapy