keyword
MENU ▼
Read by QxMD icon Read
search

grape seed

keyword
https://www.readbyqxmd.com/read/29331852/no-time-to-waste-organic-waste-nanosizing-converts-remains-of-food-processing-into-refined-materials
#1
Sharoon Griffin, Muhammad Sarfraz, Verda Farida, Muhammad Jawad Nasim, Azubuike P Ebokaiwe, Cornelia M Keck, Claus Jacob
Modern food processing results in considerable amounts of side-products, such as grape seeds, walnut shells, spent coffee grounds, and harvested tomato plants. These materials are still rich in valuable and biologically active substances and therefore of interest from the perspective of waste management and "up-cycling". In contrast to traditional, often time consuming and low-value uses, such as vermicomposting and anaerobic digestion, the complete conversion into nanosuspensions unlocks considerable potentials of and new applications for such already spent organic materials without the need of extraction and without producing any additional waste...
January 11, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29331224/centrifugal-partition-chromatography-enables-selective-enrichment-of-trimeric-and-tetrameric-proanthocyanidins-for-biomaterial-development
#2
Rasika S Phansalkar, Joo-Won Nam, Shao-Nong Chen, James B McAlpine, Ariene A Leme, Berdan Aydin, Ana-Karina Bedran-Russo, Guido F Pauli
Proanthocyanidins (PACs) find wide applications for human use including food, cosmetics, dietary supplements, and pharmaceuticals. The chemical complexity associated with PACs has triggered the development of various chromatographic techniques, with countercurrent separation (CCS) gaining in popularity. This study applied the recently developed DESIGNER (Depletion and Enrichment of Select Ingredients Generating Normalized Extract Resources) approach for the selective enrichment of trimeric and tetrameric PACs using centrifugal partition chromatography (CPC)...
December 21, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29328429/anthocyanins-inhibit-high-glucose-induced-renal-tubular-cell-apoptosis-caused-by-oxidative-stress-in-db-db-mice
#3
Jinying Wei, Haijiang Wu, Haiqiang Zhang, Fang Li, Shurui Chen, Baohua Hou, Yonghong Shi, Lijuan Zhao, Huijun Duan
Oxidative stress is an important contributory factor resulting the development of kidney injury in patients with diabetes. Numerous in vitro and in vivo studies have suggested that anthocyanins, natural phenols commonly existing in numerous fruits and vegetables, exhibit important antioxidative, anti‑inflammatory and antihyperlipidemic effects; however, their effects and underlying mechanisms on diabetic nephropathy (DN) have not yet been fully determined. In the present study, the regulation of apoptosis metabolism and antioxidative effects exhibited by anthocyanins [grape seed procyanidin (GSPE) and cyanidin‑3‑O‑β‑glucoside chloride (C3G)] were investigated, and the molecular mechanism underlying this process was investigated in vivo and in vitro...
January 10, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29311762/anti-inflammatory-cellular-targets-on-neutrophils-elucidated-using-a-novel-cell-migration-model-and-confocal-microscopy-a-clinical-supplementation-study
#4
T Smith, L Engelbrecht, C Smith
Background: In vivo studies have shown grape seed-derived polyphenols (GSP) to benefit in recovery from muscle injury by modulation of neutrophil infiltration into damaged tissue, thereby reducing secondary damage, as well as by facilitating an early anti-inflammatory macrophage phenotype shift. The current study aimed to provide data in this context from human models and to elucidate specific molecular targets of GSP.Using a placebo-controlled, double-blind study design, eighteen normally healthy volunteers between the ages of 18-35 years old (13 female and 5 male) were orally supplemented with 140 mg/day of GSP for 2 weeks...
2018: Journal of Inflammation
https://www.readbyqxmd.com/read/29280676/testing-for-human-norovirus-and-recovery-of-process-control-in-outbreak-associated-produce-items
#5
Kaoru Hida, Efstathia Papafragkou, Michael Kulka
The development of rapid and sensitive detection methods for human noroviruses (HuNoV) in produce items is critical, especially with the recent rise in outbreaks associated with this food commodity. In this study, 50-g portions of various produce items linked to a norovirus outbreak (celery, cucumber, lettuce, grapes, and radish) were artificially inoculated with murine norovirus (MNV-1) and concentrated either by ultracentrifugation or polyethylene glycol (PEG) precipitation after elution with an alkaline Tris-glycine-beef extract buffer supplemented with pectinase...
December 27, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/29279544/use-of-grape-seed-extract-for-improving-the-shear-bond-strength-of-total-etching-adhesive-to-bleached-enamel
#6
Yingxin Xu, Jianfeng Zhou, Jianguo Tan
This study was to ascertain if grape seed extract (GSE) can restore the shear bond strength (SBS) of total-etching adhesive to enamel immediately after bleaching. Immediately after bleaching with Beyond gel, different concentrations of GSE were applied to the surface of bovine enamel for 1 min before bonding of resin composite with Adper single bond 2 or All-Bond 3 adhesive. SBS values and debonding modes were recorded. Structure of the bonding interface and elements on enamel surface were analyzed by scanning electron microscopy and X-ray photoelectron spectroscopy (XPS)...
December 27, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/29240945/transcript-profiling-indicates-a-widespread-role-for-bacterial-type-phosphoenolpyruvate-carboxylase-in-malate-accumulating-sink-tissues
#7
Michael K Y Ting, Yi-Min She, William C Plaxton
Phosphoenolpyruvate carboxylase (PEPC) is an important regulatory enzyme situated at a key branch point of central plant metabolism. Plant genomes encode several plant-type PEPC (PTPC) isozymes, along with a distantly related bacterial-type PEPC (BTPC). BTPC is expressed at high levels in developing castor oil seeds where it tightly interacts with co-expressed PTPC polypeptides to form unusual hetero-octameric Class-2 PEPC complexes that are desensitized to allosteric inhibition by L-malate. Analysis of RNA-Seq and microarray transcriptome datasets revealed two distinct patterns of tissue-specific BTPC expression in vascular plants...
December 16, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29227543/edible-coating-using-a-chitosan-based-colloid-incorporating-grapefruit-seed-extract-for-cherry-tomato-safety-and-preservation
#8
Jin Sung Won, Seung Jo Lee, Hyeon Hwa Park, Kyung Bin Song, Sea C Min
Grapefruit seed extract (GSE)-containing chitosan-based coating was developed and applied to cherry tomatoes to protect them from Salmonella invasion and improve their storability. The coating colloids were produced by mixing a chitosan colloid (1% [w/w] chitosan) with GSE at various concentrations (0.5%, 0.7%, 1.0%, and 1.2% [w/w]) using high-shear mixing (10000 rpm, 2 min). Coatings with chitosan colloids containing GSE at 0.0%, 0.5%, 0.7%, and 1.0% (w/w) inactivated Salmonella on cherry tomatoes by 1.0 ± 0...
December 11, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29223045/investigation-of-antioxidant-ability-of-grape-seeds-extract-to-prevent-oxidatively-induced-dna-damage-by-gas-chromatography-tandem-mass-spectrometry
#9
Önder Aybastıer, Sam Dawbaa, Cevdet Demir
Phenolic compounds have been studied elaborately for their efficacy to improve health and to protect against a wide variety of diseases. Herein this study, different analysis methods were implemented to evaluate the antioxidant properties of catechin and cyanidin using their standard substances and as they found in the grape seeds extracts. Total phenol contents were 107.39±8.94mg GAE/g dw of grape seeds for grape seed extract (GSE) and 218.32±10.66mg GAE/g dw of grape seeds for acid-hydrolyzed grape seed extract (AcGSE)...
December 6, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29211130/dentin-sealing-and-bond-strength-evaluation-of-hema-free-and-multi-mode-adhesives-to-biomodified-dentin
#10
Renata Bacelar-Sá, Marcelo Giannini, Glaucia Maria Bovi Ambrosano, Ana Karina Bedran-Russo
This study evaluated the effect of dentin biomodification on the bond strength (BS) and sealing ability (SA) of HEMA-free and multi-mode adhesives after 24 h and 6 months of water storage. Four adhesives were tested: two multi-mode (Scotchbond Universal - SU, and Prime & Bond Elect - PB) and two HEMA-free (All-Bond 3 - AB, and G-Aenial - GA). Human third molars were selected and dentin was treated with two cross-linking agents (5% glutaraldehyde and 6.5% proanthocyanidin-rich grape seed extract - PACs) for 10 min or kept untreated (control group) (n=6)...
November 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29209877/effects-of-fish-and-grape-seed-oils-as-core-of-haloperidol-loaded-nanocapsules-on-oral-dyskinesia-in-rats
#11
Dalila Moter Benvegnú, Katiane Roversi, Raquel Cristine Silva Barcelos, Fabíola Trevizol, Camila Simonetti Pase, Hecson Jesser Segat, Verônica Tironi Dias, Ana Luiza Savian, Bruna Lopes Piccoli, Jaqueline Piccolo, Carlos Severo Dutra-Filho, Tatiana Emanuelli, Cristiane de Bona da Silva, Ruy Carlos Ruver Beck, Marilise Escobar Burger
Haloperidol is a widely used antipsychotic, despite the severe motor side effects associated with its chronic use. This study was carried out to compare oral dyskinesia induced by different formulations of haloperidol-loaded nanocapsules containing caprylic/capric triglycerides, fish oil or grape seed oil (GSO) as core, as well as free haloperidol. Haloperidol-loaded lipid-core nanocapsules formulations were prepared, physicochemical characterized and administered (0.5 mg kg-1-ip) to rats for 28 days. Oral dyskinesia was evaluated acutely and subchronically and after that cell viability and free radical generation in cortex and substantia nigra...
December 5, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/29189132/polyphenols-novel-signaling-pathways
#12
Marie-Louise Ricketts, Bradley S Ferguson
BACKGROUND: Cardiovascular disease (CVD) is currently the leading cause of death globally. The metabolic syndrome (MetS), a clustering of risk factors including hypertension, hyperglycemia, elevated low-density lipoprotein (LDL) cholesterol, reduced high-density lipoprotein (HDL) cholesterol and increased visceral adiposity, is a significant risk factor for the development of CVD. Non-alcoholic fatty liver disease (NAFLD), often referred to as the hepatic manifestation of MetS, is a constellation of progressive liver disorders closely linked to obesity, diabetes, and insulin resistance...
November 29, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29188040/evaluation-of-peanut-skin-and-grape-seed-extracts-to-inhibit-growth-of-foodborne-pathogens
#13
Jason Levy, Renee R Boyer, Andrew P Neilson, Sean F O'Keefe, Hyun Sik S Chu, Robert C Williams, Melanie R Dorenkott, Katheryn M Goodrich
Peanut skin extract (PSE) and grape seed extract (GSE) are derived from waste products in the wine and peanut industries, respectively. Both have high concentrations of polyphenols, known to possess antioxidant and antimicrobial properties. PSE primarily contains "A-type" procyanidins, while GSE primarily contains "B-type" procyanidins. These differ structurally, but are both isomers of epicatechin dimers. The objective of this study was to evaluate the antimicrobial effects of PSE containing A-type procyanidins and GSE containing B-type procyanidins against select foodborne pathogens (Listeria monocytogenes, Escherichia coli O157:H7, and Salmonella Typhimurium)...
November 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/29178771/effect-of-different-concentrations-and-application-times-of-proanthocyanidin-gels-on-dentin-erosion
#14
Ana Paula Boteon, Anuradha Prakki, Marília Afonso Rabelo Buzalaf, Daniela Rios, Heitor Marques Honorio
PURPOSE: To analyze the effect of different concentrations and application times of proanthocyanidin gels on dentin before an erosive challenge in order to evaluate if there is a dose-response or application time-response relationship in the use of these gels for erosion prevention. METHODS: 80 bovine root dentin blocks were randomly and equally divided into 10 groups and treated according to the two factors under study (purified grape seed proanthocyanidin gel concentration and time of application): 0...
April 2017: American Journal of Dentistry
https://www.readbyqxmd.com/read/29175668/grape-seed-procyanidin-extract-ameliorates-lead-induced-liver-injury-via-mirna153-and-akt-gsk-3%C3%AE-fyn-mediated-nrf2-activation
#15
Biying Liu, Huijie Jiang, Jingjing Lu, Ruiqi Baiyun, Siyu Li, Yueying Lv, Da Li, Hao Wu, Zhigang Zhang
Lead-induced hepatotoxicity is characterized by an extensive oxidative stress. Grape seed procyanidin extract (GSPE) possesses abundant biological activities. Herein, we investigated the protective role of GSPE against lead-induced liver injury and determined the potential molecular mechanisms. In vivo, rats were treated with/without lead acetate (PbAc) (0.05%, w/v) in the presence/absence of GSPE (200 mg/kg). In vitro, hepatocytes were pretreated with/without GSPE (100 μg/ml) in the presence/absence of PbAc (100 μM)...
October 12, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29174497/antioxidant-action-of-grape-seed-polyphenols-and-aerobic-exercise-in-improving-neuronal-number-in-the-hippocampus-is-associated-with-decrease-in-lipid-peroxidation-and-hydrogen-peroxide-in-adult-and-middle-aged-rats
#16
S Abhijit, Sunil Jamuna Tripathi, V Bhagya, B S Shankaranarayana Rao, Muthangi V Subramanyam, S Asha Devi
The present study explored the effects of swimming training and grape seed proanthocyanidin extract (GSPE) on neuronal survival in the hippocampus (HC) of middle-aged rats along with oxidative stress (OS) parameters. Further, the bioavailability of the GSPE, catechin, epicatechin and gallic acid were measured in the HC and plasma. Male Wistar rats were grouped into: sedentary control, SE-C; swimming trained, SW-T; SE-C, supplemented sedentary, SE-C(PA) and swimming trainees, SW-T(PA). The supplement was a daily dose of 400mg GSPE/kg body weight...
November 22, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29172735/effects-of-ganoderma-rhodiola-and-grape-seed-extracts-on-the-glucuronidation-and-oral-bioavailability-of-resveratrol-in-rats
#17
Zhaoqing Cong, Man Zhou, Feifei Yang, Chunyu Liu, Ruile Pan, Qi Chang, Xinmin Liu, Yonghong Liao
Herb extracts were shown to inhibit the activity of UDP-glucuronosyltransferases (UGTs) in vitro. However, the actual in vivo effect of the inhibitory ability on oral bioavailability is yet verified. In this study, resveratrol (RES) was used as a model drug to study the effect of three Chinese herb extracts, Ganoderma, Rhodiola and grape seed, on the in vitro and in vivo inhibition of glucuronidation and the in vivo bioavailability of RES. Overall, although herb extracts might show inhibition on glucuronidation of RES in vitro and in vivo, the inhibition of glucuronidation did not necessarily mean to improve the in vivo bioavailability of RES...
November 26, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29169010/oxidative-stress-burden-inhibits-spermatogenesis-in-adult-male-rats-testosterone-protective-effect
#18
Samy Makary, Mohamed Abdo, Ereny Fekry
In this study, we aimed to investigate the protective effects of androgens, using letrozole (LET; an aromatase inhibitor), grape seed extract (GSE; a naturally occurring aromatase inhibitor and antioxidant), and testosterone propionate (Tp), against methotrexate (MTX)-induced testicular toxicity in adult male rats. MTX has been shown to induce oxidative stress and exhibit antiproliferative effects in the testes. Adult male rats received oral saline gavage (control group with no treatment), the potential protective agents (LET, GSE, or Tp) alone, MTX alone, or a combination of one of the potential protective agents and MTX...
November 23, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/29162031/norgal-extraction-and-de-novo-assembly-of-mitochondrial-dna-from-whole-genome-sequencing-data
#19
Kosai Al-Nakeeb, Thomas Nordahl Petersen, Thomas Sicheritz-Pontén
BACKGROUND: Whole-genome sequencing (WGS) projects provide short read nucleotide sequences from nuclear and possibly organelle DNA depending on the source of origin. Mitochondrial DNA is present in animals and fungi, while plants contain DNA from both mitochondria and chloroplasts. Current techniques for separating organelle reads from nuclear reads in WGS data require full reference or partial seed sequences for assembling. RESULTS: Norgal (de Novo ORGAneLle extractor) avoids this requirement by identifying a high frequency subset of k-mers that are predominantly of mitochondrial origin and performing a de novo assembly on a subset of reads that contains these k-mers...
November 21, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29158566/graphene-quantum-dots-for-cell-proliferation-nucleus-imaging-and-photoluminescent-sensing-applications
#20
Mukesh Kumar Kumawat, Mukeshchand Thakur, Raju B Gurung, Rohit Srivastava
We report a simple one-pot microwave assisted "green synthesis" of Graphene Quantum Dots (GQDs) using grape seed extract as a green therapeutic carbon source. These GQDs readily self-assemble, hereafter referred to as "self-assembled" GQDs (sGQDs) in the aqueous medium. The sGQDs enter via caveolae and clathrin-mediated endocytosis and target themselves into cell nucleus within 6-8 h without additional assistance of external capping/targeting agent. The tendency to self-localize themselves into cell nucleus also remains consistent in different cell lines such as L929, HT-1080, MIA PaCa-2, HeLa, and MG-63 cells, thereby serving as a nucleus labelling agent...
November 20, 2017: Scientific Reports
keyword
keyword
120445
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"