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https://www.readbyqxmd.com/read/28720935/technological-options-to-control-quality-of-fish-burgers
#1
A Danza, A Conte, M A Del Nobile
This research was focused on preservation strategies applied to develop fish burgers enriched with tomato flour and extra-virgin olive oil. The effects of three different gas mixtures (5:95 O2/CO2; 10:60:30 O2/CO2/N2 and 5:50:45 O2/CO2/N2) on burger quality were analyzed by monitoring microbial cell load of main spoilage microorganisms, pH and sensory properties. As expected, modified atmosphere packaging significantly affected mesophilic bacteria with a reduction of about 2 log cycles for samples under 5% O2 and 95% CO2...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28713708/the-healing-effect-of-grape-seed-oil-enema-with-or-without-sesame-oil-in-acetic-acid-induced-ulcerative-colitis-of-rats
#2
Fatemeh Hosseinzadeh, Moosa Salehi, Nader Tanideh, Davood Mehrabani, Azadeh Sayarifard, Anahita Sedighi
BACKGROUND: Inflammatory bowel diseases contain two digestive system diseases, ulcerative colitis (UC) and Crohn's disease with unclear causes. The aim of present study was to investigate the therapeutic effects of administration of the Sesame oil (SO) and grape seed oil (GSO) as enema route in rats suffering from experimental acetic acid induced UC. METHODS: Eighty male rats were randomly allocated into 8 equal groups as health control (HC1) without any disease treated with 1 ml of normal saline as enema; HC2 received SO; HC3 received GSO; negative control (NC) with induced UC receiving 1 ml of normal saline as enema; and positive control (PC) with induced UC treated by asacol...
May 2017: World Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28697472/protective-effects-of-grape-stem-extract-against-uvb-induced-damage-in-c57bl-mice-skin
#3
Denis Nchang Che, Guang Hua Xie, Byoung Ok Cho, Jae Young Shin, Hyun Ju Kang, Seon Il Jang
Humans have become exposed to another form of a trait which is ultraviolet B (UVB) radiation reaching the earth's surface. This has become a major source of oxidative stress that ultimately leads to inflammation, DNA damage, photoaging and pigmentation disorders etc. Although several studies have shown the photo-protective role of different grape parts like the fruits and seeds, little or no data demonstrating the in vivo photo-protective role of grape stem, which is the most discarded part of the grape are available...
June 29, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28693689/neuroprotective-effects-of-grape-seed-procyanidin-extract-on-ischemia-reperfusion-brain-injury-%C3%A2
#4
Kong Xiangyi, Guan Jian, Gong Shun, Wang Renzhi
<strong>Objective</strong> Oxidative stress (OS) plays a crucial role in ischemic stroke. Grape seed procyanidin extract (GSPE) was reported to be a critical regulator of OS. We hypothesized that GSPE might also be protective in ischemia-reperfusion brain injury. This study aimed to explore whether GSPE administration can protect mice from ischemia-reperfusion brain injury.<strong>Methods</strong> Transient middle cerebral artery occlusion (MCAO) was conducted followed by reperfusion for 24 hours to make ischemia-reperfusion brain injury in mice that received GSPE (MCAOG, n=60) or normal saline (MCAONS, n=60)...
June 10, 2017: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
https://www.readbyqxmd.com/read/28692939/oligomeric-proanthocyanidin-derived-from-grape-seeds-inhibited-nf-%C3%AE%C2%BAb-signaling-in-activated-hsc-involvement-of-jnk-erk-mapk-and-pi3k-akt-pathways
#5
Min Jiang, Yan-Ling Wu, Xia Li, Yu Zhang, Kai-Li Xia, Ben-Wen Cui, Li-Hua Lian, Ji-Xing Nan
In current study, we aimed to reveal the potential antifibrotic effects of oligomeric proanthocyanidin (OPC) from grape seeds on lipopolysaccharide (LPS)-activated, HSC-T6, a rat hepatic stellate cell line. HSC-T6 cells were treated with OPC 1h prior to LPS, and then incubated for indicated time. OPC inhibited cells viability of HSC-T6 cells and decrease protein expression of collagen I, α-smooth muscle actin (α-SMA), tissue inhibitors of metalloproteinases I (TIMP-1) on LPS-induced HSC-T6 cells. OPC also significantly inhibited phosphorylation of LPS-stimulated phosphatidylinositol 3-kinase (PI3K), protein kinase B (Akt), extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK)...
July 7, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28687392/characterization-and-in-vitro-anticancer-properties-of-chitosan-microencapsulated-flavan-3-ols-rich-grape-seed-extracts
#6
Michelangelo Iannone, Rosario Mare, Donatella Paolino, Agnese Gagliardi, Francesca Froiio, Donato Cosco, Massimo Fresta
Studies have fully demonstrated that a diet rich in fruit and vegetables may reduce the incidence of tumors. In particular, Grape Seed Extract (GSE) has been shown to carry on chemopreventive and antitumor activity thanks to the numerous beneficial substances it contains. The purpose of this work was to create a biocompatible matrix containing GSE in order to obtain microparticles able to modulate its biopharmaceutical parameters. The spray-drying technique was chosen in order to realize chitosan microparticles characterized by a mean diameter of 4-10μm and a positive surface charge that decreased after GSE encapsulation...
July 4, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28677803/grape-seed-procyanidin-b2-ameliorates-hepatic-lipid-metabolism-disorders-in-db-db-mice
#7
Mei Yin, Pei Zhang, Fei Yu, Zhen Zhang, Qian Cai, Weida Lu, Baoying Li, Weidong Qin, Mei Cheng, Hao Wang, Haiqing Gao
Diabetes is commonly associated with liver lipid metabolism disorders. AMP-activated protein kinase (AMPK) has a key role in regulating lipid metabolism. Grape seed procyanidin B2 (GSPB2), a natural polyphenol polymer, ameliorates mitochondrial dysfunction and inhibits oxidative stress or apoptosis via AMPK pathways. In the present study, the hypothesis that GSPB2 treatment may ameliorate liver lipid metabolic disorders by activating AMPK and downstream pathways was tested in diabetic mice. Db/m mice were used as controls, and diabetic db/db mice were randomly divided into 2 groups for treatment: Vehicle and GSPB2 (30 mg/kg/day for 10 weeks)...
June 30, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28659730/acute-selective-bioactivity-of-grape-seed-proanthocyanidins-on-enteroendocrine-secretions-in-the-gastrointestinal-tract
#8
Àngela Casanova-Martí, Joan Serrano, M Teresa Blay, Ximena Terra, Anna Ardévol, Montserrat Pinent
Background: Enteroendocrine cells respond to food components by secreting an array of hormones that regulate several functions. We have previously shown that grape seed proanthocyanidins (GSPE) modulate GLP-1 levels. Objective: To deepen on the knowledge of the mechanisms used by GSPE to increase GLP-1, and extend it to its role at modulation of other enterohormones. Design: We used an ex vivo system to test direct modulation of enterohormones; STC-1 cells to test pure phenolic compounds; and rats to test the effects at different gastrointestinal segments...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28654207/the-effect-of-obesity-and-repeated-exposure-on-pharmacokinetic-response-to-grape-polyphenols-in-humans
#9
Janet A Novotny, Tzu-Ying Chen, Anton I Terekhov, Sarah K Gebauer, David J Baer, Lap Ho, Giulio M Pasinetti, Mario G Ferruzzi
SCOPE: Evidence suggests that dietary pattern may affect polyphenol absorption and/or metabolism. Further, obesity is associated with lower circulating nutrients, though the reason is unclear. We investigated the pharmacokinetic (PK) response of polyphenols in obese/overweight vs. lean individuals before and after repeated dosing with of grape polyphenols. METHODS AND RESULTS: A pilot study was conducted in which PK challenges were administered before and after 11 days of repeated dosing with polyphenols...
June 27, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28629290/functional-foods-how-functional-are-they-a-case-report-of-supplement-induced-psychosis
#10
Priyanka Yadav, Kyle Stigall, Hannah E Johnson, Abner O Rayapati, Nitin Chopra
There is rising evidence of patients' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28610733/comparison-of-fortified-sfursat-and-passito-wines-produced-from-fresh-and-dehydrated-grapes-of-aromatic-black-cv-moscato-nero-vitis-vinifera-l
#11
Carolina Ossola, Simone Giacosa, Fabrizio Torchio, Susana Río Segade, Alberto Caudana, Enzo Cagnasso, Vincenzo Gerbi, Luca Rolle
Moscato nero d'Acqui is an Italian aromatic black winegrape variety characterized by a low content of anthocyanins (mostly tri-substituted), a satisfactory content of high molecular mass tannins, and a fair amount of terpenes. The grapes were subjected to a postharvest dehydration process under controlled thermohygrometric conditions (16-18°C, 55-70 RH%, 0.6m/s air speed) with the aim to produce three different special wine types (fortified, sfursat, and passito) from fresh, partially dehydrated (27°Brix), and withered (36°Brix) grapes, respectively...
August 2017: Food Research International
https://www.readbyqxmd.com/read/28610729/targeted-and-untargeted-high-resolution-mass-approach-for-a-putative-profiling-of-glycosylated-simple-phenols-in-hybrid-grapes
#12
Chiara Barnaba, Eduardo Dellacassa, Giorgio Nicolini, Mattia Giacomelli, Tomas Roman Villegas, Tiziana Nardin, Roberto Larcher
Vitis vinifera is one of the most widespread grapevines around the world representing the raw material for high quality wine production. The availability of more resistant interspecific hybrid vine varieties, developed from crosses between Vitis vinifera and other Vitis species, has generated much interest, also due to the low environmental effect of production. However, hybrid grape wine composition and varietal differences between interspecific hybrids have not been well defined, particularly for the simple phenols profile...
August 2017: Food Research International
https://www.readbyqxmd.com/read/28596775/abnormal-endogenous-repression-of-ga-signaling-in-a-seedless-table-grape-cultivar-with-high-berry-growth-response-to-ga-application
#13
Atiako K Acheampong, Chuanlin Zheng, Tamar Halaly, Lisa Giacomelli, Yumiko Takebayashi, Yusuke Jikumaru, Yuji Kamiya, Amnon Lichter, Etti Or
Gibberellin (GA) application is routinely used in the table grape industry to increase berry size and cluster length. Although grapevine cultivars show a wide range of growth responsiveness to GA3 application, the reasons for these differences is unclear. To shed light on this issue, two commercial grapevine cultivars with contrasting berry response to GA were selected for comparative analysis, in which we tested if the differences in response: (1) is organ-specific or cultivar-related; (2) will be reflected in qualitative/quantitative differences in transcripts/proteins of central components of GA metabolism and signaling and levels of GA metabolites...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28593720/phytoestrogen-rich-natural-preparation-for-treatment-of-climacteric-syndrome-and-atherosclerosis-prevention-in-perimenopausal-women
#14
T V Kirichenko, V A Myasoedova, V A Orekhova, A L Ravani, N A Nikitina, A V Grechko, I A Sobenin, A N Orekhov
The present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric syndrome and progression of atherosclerosis. Study participants were treated with placebo or phytoestrogen-rich natural preparation Karinat based on grape (Vitis vinifera) seeds, green tea (Camellia sinensis) leaves, hop (Hunulus lupulus) cone powder and garlic (Allium sativum) powder. The dynamics of climacteric syndrome was evaluated by Kupperman Index and Utian Quality of Life Scale...
June 8, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28587960/mathematical-modeling-of-gallic-acid-release-from-chitosan-films-with-grape-seed-extract-and-carvacrol
#15
Javiera F Rubilar, Rui M S Cruz, Rommy N Zuñiga, Igor Khmelinskii, Margarida C Vieira
Controlled release of antimicrobial and antioxidant compounds from packaging films is of utmost importance for extending the shelf-life of perishable foods. This study focused on the mathematical modeling of gallic acid release into an aqueous medium from three chitosan films, formulated with grape seed extract (GSE) and carvacrol. We quantified the release by HPLC technique during 30days at three temperatures (5, 25 and 45°C). The diffusion coefficients, varying with temperature according to an Arrhenius-type relationship, and the respective activation energies for Film-1 and Film-2 were, respectively [Formula: see text] m(2)s(-1) and [Formula: see text] m(2)s(-1), Ea1=58kJmol(-1) and Ea2=60kJmol(-1) as obtained from the Fickian fit...
June 3, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28578061/effects-of-the-combination-of-%C3%AF-3-pufas-and-proanthocyanidins-on-the-gut-microbiota-of-healthy-rats
#16
Sara Ramos-Romero, Mercè Hereu, Eunice Molinar-Toribio, María Pilar Almajano, Lucía Méndez, Isabel Medina, Núria Taltavull, Marta Romeu, Maria Rosa Nogués, Josep Lluís Torres
ω-3 Polyunsaturated fatty acids (PUFAs) reduce risk factors for cardiovascular diseases (CVD) and other pathologies that involve low-grade inflammation. They have recently been shown to exert complementary functional effects with proanthocyanidins. As the reduction of health-promoting gut bacteria such as lactobacilli and bifidobacteria has been linked to a number of alterations in the host, the aim of this study was to determine whether PUFAs and proanthocyanidins also cooperate in maintaining well-balanced microbiota...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28578033/influence-of-omega-3-pufas-on-the-metabolism-of-proanthocyanidins-in-rats
#17
Eunice Molinar-Toribio, Sara Ramos-Romero, Elisabet Fuguet, Núria Taltavull, Lucía Méndez, Marta Romeu, Isabel Medina, Josep Lluís Torres, Jara Pérez-Jiménez
Studies of the bioavailability of proanthocyanidins usually consider them independently of other dietary constituents, while there is a tendency in the field of functional foods towards the combination of different bioactive compounds in a single product. This study examined the long-term effects of ω-3 polyunsaturated fatty acids of marine origin on the metabolic fate of grape proanthocyanidins. For this, female adult Wistar-Kyoto rats were fed (18weeks) with a standard diet supplemented or not with eicosapentaenoic acid/docosahexaenoic acid (1:1, 16...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28568316/influence-of-diabetes-on-plasma-pharmacokinetics-and-brain-bioavailability-of-grape-polyphenols-and-their-phase-ii-metabolites-in-the-zucker-diabetic-fatty-rat
#18
Tzu-Ying Chen, Mario G Ferruzzi, Qing-Li Wu, James E Simon, Stephen T Talcott, Jun Wang, Lap Ho, George Todd, Bruce Cooper, Giulio M Pasinetti, Elsa M Janle
SCOPE: The effect of diabetes on the pharmacokinetics, bioavailability and brain distribution of grape polyphenols and select metabolites was studied in the Zucker diabetic fatty (ZDF) rat model. METHODS AND RESULTS: (ZDF) rats and their lean controls (LN) were dosed with a Standardized Grape Polyphenol (SGP) Mixture consisting of grape seed extract, Concord grape juice and resveratrol (RES) by oral gavage for 10 days. An 8 hour pharmacokinetic study was performed...
June 1, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28548949/dietary-grape-seed-proanthocyanidins-inactivate-regulatory-t-cells-by-promoting-ner-dependent-dna-repair-in-dendritic-cells-in-uvb-exposed-skin
#19
Mudit Vaid, Ram Prasad, Tripti Singh, Santosh K Katiyar
Ultraviolet B (UVB) radiation induces regulatory T cells (Treg cells) and depletion of these Treg cells alleviates immunosuppression and inhibits photocarcinogenesis in mice. Here, we determined the effects of dietary grape seed proanthocyanidins (GSPs) on the development and activity of UVB-induced Treg cells. C3H/HeN mice fed a GSPs (0.5%, w/w)-supplemented or control diet were exposed to UVB (150 mJ/cm2) radiation, sensitized to 2,4-dinitrofluorobenzene (DNFB) and sacrificed 5 days later. FACS analysis indicated that dietary GSPs decrease the numbers of UVB-induced Treg cells...
May 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28534957/grape-seed-proanthocyanidin-inhibits-inflammatory-responses-in-hepatic-stellate-cells-by-modulating-the-mapk-akt-and-nf-%C3%AE%C2%BAb-signaling-pathways
#20
Jin-Woo Lee, Young Il Kim, Youngchul Kim, Minji Choi, Seoyeon Min, Yong Hoon Joo, Sung-Vin Yim, Namhyun Chung
In the present study, we aimed to investigate the molecular mechanisms and prophylactic effects of grape seed proanthocyanidin (GSP) on lipopolysaccharide (LPS)-stimulated human hepatic stellate cells (HSCs). Cell counting and MTT assays were used to assess cell viability in the absence or presence of GSP. Reverse transcription-quantitative PCR (RT-qPCR) was performed for several inflammation-related genes (NOD1, NOD2, TLR2, TLR4, IL-1 β, IL-6, IL-8, iNOS and COX-2). The expression of anti-inflammatory cell signaling molecules, including c-Jun N-terminal kinase (JNK), p38, extracellular signal regulated kinase (ERK), Akt, nuclear factor-κB (NF-κB), inhibitory-κBα (IκBα), iNOS and COX-2, was evaluated by western blot analysis...
May 19, 2017: International Journal of Molecular Medicine
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