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https://www.readbyqxmd.com/read/28335440/profile-of-polyphenol-compounds-of-five-muscadine-grapes-cultivated-in-the-united-states-and-in-newly-adapted-locations-in-china
#1
Zheng Wei, Jianming Luo, Yu Huang, Wenfeng Guo, Yali Zhang, Huan Guan, Changmou Xu, Jiang Lu
Polyphenol compositions and concentrations in skins and seeds of five muscadine grapes (cv. "Noble", "Alachua", "Carlos", "Fry", and "Granny Val") cultivated in the United States (Tallahassee-Florida, TA-FL) and South China (Nanning-Guangxi, NN-GX and Pu'er-Yunnan, PE-YN) were investigated, using ultra performance liquid chromatography tandem triple quadrupole time-of-flight mass spectrometry (UPLC Triple TOF MS/MS). Fourteen ellagitannins were newly identified in these muscadine grapes. The grapes grown in NN-GX accumulated higher levels of ellagic acid, methyl brevifolin carboxylate, and ellagic acid glucoside in skins, and penta-O-galloyl-glucose in seeds...
March 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28330296/application-of-pectinases-for-recovery-of-grape-seeds-phenolics
#2
Petra Štambuk, Dora Tomašković, Ivana Tomaz, Luna Maslov, Domagoj Stupić, Jasminka Karoglan Kontić
Grape marc seeds contain large amounts of different polyphenolic compounds so they can be used for the recovery of these classes of compounds. A new green extraction method for the recovery of phenols from the grape seeds was developed. To provide a high quality extract sourced from natural product by using enzymes as alternative solvents and spending less energy, it is impeccable to call this method "green". Furthermore, this method was optimized by finding out which conditions provide the best possible results and achieving the maximum recovery of polyphenols from grape seeds...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28320623/kinetics-and-evolved-gas-analysis-for-pyrolysis-of-food-processing-wastes-using-tga-ms-ft-ir
#3
Gamzenur Özsin, Ayşe Eren Pütün
The objective of this study was to identify the pyrolysis of different bio-waste produced by food processing industry in a comprehensible manner. For this purpose, pyrolysis behaviors of chestnut shells (CNS), cherry stones (CS) and grape seeds (GS) were investigated by thermogravimetric analysis (TGA) combined with a Fourier-transform infrared (FT-IR) spectrometer and a mass spectrometer (MS). In order to make available theoretical groundwork for biomass pyrolysis, activation energies were calculated with the help of four different model-free kinetic methods...
March 17, 2017: Waste Management
https://www.readbyqxmd.com/read/28315767/the-properties-of-chitosan-and-gelatin-films-incorporated-with-ethanolic-red-grape-seed-extract-and-ziziphora-clinopodioides-essential-oil-as-biodegradable-materials-for-active-food-packaging
#4
Yasser Shahbazi
The aim of this study was to improve different characteristics including antibacterial, antioxidant, physical and mechanical properties of chitosan (Ch) and gelatin (Ge) films by incorporating Ziziphora clinopodioides essential oil (ZEO; 0 and 1% v/w) and ethanolic grape seed extract (GSE; 0 and 1% v/w). The main compounds of the ZEO were carvacrol (65.22%) and thymol (19.51%). According to our findings, addition of aforementioned materials could improve total phenolic content, antibacterial and antioxidant activities, thickness and also water vapor barrier property...
March 16, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28300665/grape-seed-extract-ameliorates-bleomycin-induced-mouse-pulmonary-fibrosis
#5
Qi Liu, Jun-Xia Jiang, Ya-Nan Liu, Yan Guan, Wei Zhao, Yong-Liang Jia, Xin-Wei Dong, Yun Sun, Qiang-Min Xie
Pulmonary fibrosis is common in a variety of inflammatory lung diseases, such as interstitial pneumonia, chronic obstructive pulmonary disease, and silicosis. There is currently no effective clinical drug treatment. It has been reported that grape seed extracts (GSE) has extensive pharmacological effects with minimal toxicity. Although it has been found that GSE can improve the lung collagen deposition and fibrosis pathology induced by bleomycin in rat, its effects on pulmonary function, inflammation, growth factors, matrix metalloproteinases and epithelial-mesenchymal transition remain to be researched...
March 11, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28300023/optimization-and-validation-of-a-residue-analysis-method-for-glyphosate-glufosinate-and-their-metabolites-in-plant-matrixes-by-liquid-chromatography-with-tandem-mass-spectrometry
#6
Dasharath P Oulkar, Sandip Hingmire, Arnab Goon, Manjusha Jadhav, Bharat Ugare, Ahammed Shabeer Thekkumpurath, Kaushik Banerjee
A sensitive and accurate LC with tandem MS (MS/MS)-based method was developed and validated for the analysis of the herbicide glyphosate, its metabolite aminomethylphosphonic acid (AMPA), and glufosinate after derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl) in various plant matrixes. The method also covers direct analysis of the glufosinate metabolites 3-methylphosphinicopropionic acid (3-MPPA) and N-acetyl-glufosinate (NAG). The homogenized samples were extracted with 0.1% formic acid in water-dichloromethane (50 + 50)...
March 23, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28299325/protective-effects-of-the-segmental-renal-artery-clamping-technique-on-ischemia-reperfusion-injury-in-db-db-diabetic-mice
#7
Chao Liang, Jundong Zhu, Chenkui Miao, Shangqian Wang, Lei Zhang, Pu Li, Zengjun Wang, Pengfei Shao
Renal ischemia-reperfusion (I/R) injury is inevitable in partial nephrectomy and other kidney surgeries, with a higher incidence in patients with renal insufficiency. This study aimed to investigate the protective effects of precise segmental renal artery clamping (SRAC) against renal I/R injury in db/db diabetic mice, compared with conventional renal artery clamping (RAC). Grape seed extract, a powerful free radical scavenger, was administered to diabetic mice for 4 weeks before operation in subgroups (30 mg/kg/d)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28295656/effect-of-dietary-polyphenol-rich-grape-seed-on-growth-performance-antioxidant-capacity-and-ileal-microflora-in-broiler-chicks
#8
S H Abu Hafsa, S A Ibrahim
In this study, we examined the effect of dietary supplementation with grape seed (GS) on the performance, carcass traits, plasma biochemistry, antioxidant status and ileal microflora in broilers. Experiment diets included a control diet (without additive) and three levels of GS powder (10, 20 and 40 g/kg of diet). Each diet was fed to a total of 300 one-day-old Cobb-500 chicks for 42 days. The addition of 20 g/kg of GS to the basal diet increased final body weight and body weight gain, improved the feed conversion ratio and did not affect feed intake...
March 15, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28290138/rare-earth-elements-distribution-in-grapevine-varieties-grown-on-volcanic-soils-an-example-from-mount-etna-sicily-italy
#9
Carmelisa D'Antone, Rosalda Punturo, Carmela Vaccaro
A geochemical and statistical approach has allowed identifying in rare earth elements (REEs) absorption a good fingerprinting mark for determining the territoriality and the provenance of Vitis vinifera L. in the district of Mount Etna (southern Italy). Our aim is to define the REEs distribution in different parts of the plants which grow in the same volcanic soil and under the same climate conditions, and therefore to assess whether REEs distribution may reflect the composition of the provenance soil or if plants can selectively absorb REEs in order to recognize the fingerprint in the Etna Volcano soils as well as the REEs pattern characteristic of each cultivar of V...
April 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28283930/modeling-of-the-nanoparticles-absorption-under-a-gastrointestinal-simulated-ambient-condition
#10
Katherina Fernández, Marlene Roeckel, Edgardo Canales, Javiera Dumont
Proanthocyanidins (PAs) have several bioactivities, but they are unstable in the digestive tract and possess low bioavailability. Nanoencapsulation stabilizes these compounds for oral administration. The intestinal absorption of grape seed and skin extracts, and the poly-lactic acid (PLA) nanoparticles loaded with such extracts was modeled, taking into consideration physicochemical process parameters, evaluating the PAs concentration profile in the human small intestine. Density (ρ), solubility, viscosity (μ), diffusion coefficient (D), and the global mass transfer coefficient (K) for both substrates were estimated, simulating their passing from the intestine into the blood at 37°C...
March 10, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28274120/differences-in-vvufgt-and-vvmyba1-gene-expression-levels-and-phenolic-composition-in-table-grape-vitis-vinifera-l-red-globe-and-its-somaclonal-variant-pink-globe
#11
Luis Bustamante, Vania Saez, Patricio Hinrichsen, Maria H Castro, Carola Vergara, Dietrich Von Baer, Claudia Mardones
A novel 'Red Globe' (RG)-derived grape variety, 'Pink Globe' (PG), was described and registered as a new genotype, with earlier ripening and sweeter taste than that of RG. Microsatellite analysis revealed that PG and RG are undifferentiable; however, the PG VvmybA1c contains six SNPs within the coding and non-coding region, possible related to the reduced VvmybA1 expression levels. Conversely, HPLC-DAD-ESI-MS/MS analysis showed significantly lower anthocyanin content in PG skin than in RG skin and PG had no detectable trihydroxylated anthocyanins...
March 8, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28260647/a-lipidomic-study-on-the-regulation-of-inflammation-and-oxidative-stress-targeted-by-marine-%C3%AF-3-pufa-and-polyphenols-in-high-fat-high-sucrose-diets
#12
Gabriel Dasilva, Manuel Pazos, Eduardo García-Egido, José M Gallardo, Sara Ramos-Romero, Josep Lluís Torres, Marta Romeu, María-Rosa Nogués, Isabel Medina
The ability of polyphenols to ameliorate potential oxidative damage of ω-3 PUFAs when they are consumed together and then, to enhance their potentially individual effects on metabolic health is discussed through the modulation of fatty acids profiling and the production of lipid mediators. For that, the effects of the combined consumption of fish oils and grape seed procyanidins on the inflammatory response and redox unbalance triggered by high-fat high-sucrose (HFHS) diets were studied in an animal model of Wistar rats...
February 21, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28253178/the-effect-of-proanthocyanidins-and-chlorhexidine-on-the-bond-strength-of-glass-fiber-posts-to-root-dentin
#13
Carla Cecilia Alandia-Román, Sergio Augusto Freitas Vincenti, Francisca Daniele Jardilino Silami, Renata Espíndola Silveira, Gustavo Col Dos Santos Pinto, Fernanda de Carvalho Panzeri Pires-de-Souza
In this study, the influence of different irrigant solutions applied before cementation on the bond strength (BS) of glass fiber posts to root dentin was evaluated. Thirty endodontically treated maxillary canines of similar length were selected and divided into 3 groups (n = 10) according to the irrigant solution used before post cementation: 1% sodium hypochlorite (NaOCl; control), 2% chlorhexidine (CHX), or a 6.5% grape seed extract (GSE) cross-linking agent. After cementation of the posts, the roots were transversely sectioned to create 2 discs (2 mm) for each of the root thirds: coronal, middle, and apical...
March 2017: General Dentistry
https://www.readbyqxmd.com/read/28250660/the-hydroalcoholic-extract-of-matricaria-chamomilla-suppresses-migration-and-invasion-of-human-breast-cancer-mda-mb-468-and-mcf-7-cell-lines
#14
Mohsen Nikseresht, Ali Mohammad Kamali, Hamid Reza Rahimi, Hamdollah Delaviz, Mehdi Akbartabar Toori, Iraj Ragerdi Kashani, Reza Mahmoudi
BACKGROUND: Matricaria chamomilla is an aromatic plant with antioxidant, anticancer, and anti-inflammatory properties. However, the inhibitory role of M. chamomilla on migration and invasion of human breast cancer cells remains unclear. OBJECTIVE: This study investigated the methods to evaluate these anticancer mechanisms of M. chamomilla on human breast cancer MCF-7 and MDA-MB-468 cell lines. MATERIALS AND METHODS: The cells were treated with hydroalcoholic extract of M...
January 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28247575/assessment-of-the-effect-of-grape-seed-cake-inclusion-in-the-diet-of-healthy-fattening-finishing-pigs
#15
I Taranu, M Habeanu, M A Gras, G C Pistol, N Lefter, M Palade, M Ropota, V Sanda Chedea, D E Marin
Modulatory capacity of bioactive compounds from different wastes has been scarcely investigated in pigs. This study aimed to evaluate the effects of dietary inclusion of grape seed cakes (GS diet) on performance and plasma biochemistry parameters as health indicators, as well as on several markers related to inflammation and antioxidant defence in the liver of fattening-finishing pigs. Twelve cross-bred pigs (TOPIG) were randomly assigned to one of two experimental diets: control and 5% grape seed cake diet during finishing period (24 days)...
March 1, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28246402/grape-seed-proanthocyanidins-prevent-irradiation-induced-differentiation-of-human-lung-fibroblasts-by-ameliorating-mitochondrial-dysfunction
#16
XiaoHong Yang, Tao Liu, Bo Chen, Fangqin Wang, Qunfang Yang, XiaoHong Chen
Radiation-induced lung fibrosis (RILF) is a long-term adverse effect of curative radiotherapy. The accumulation of myofibroblasts in fibroblastic foci is a pivotal feature of RILF. In the study, we found the inhibitory effect of grape seed proanthocyanidins (GSPs) on irradiation-induced differentiation of human fetal lung fibroblasts (HFL1). To explore the mechanism by which GSPs inhibit fibroblast differentiation, we measured the reactive oxygen species (ROS) levels, mitochondrial function, mitochondrial dynamics, glycolysis and the signaling molecules involved in fibroblast transdifferentiation...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28224250/abscisic-acid-sucrose-and-auxin-coordinately-regulate-berry-ripening-process-of-the-fujiminori-grape
#17
Haifeng Jia, Zhenqiang Xie, Chen Wang, Lingfei Shangguan, Ning Qian, Mengjie Cui, Zhongjie Liu, Ting Zheng, Mengqi Wang, Jinggui Fang
The aim of this study was to examine the effect of abscisic acid (ABA), sucrose, and auxin on grape fruit development and to assess the mechanism of these three factors on the grape fruit ripening process. Different concentrations of ABA, sucrose, and auxin were used to treat the grape fruit, and the ripening-related indices, such as physiological and molecular level parameters, were analyzed. The activity of BG protein activity was analyzed during the fruit development. Sucrose, ABA, and auxin influenced the grape fruit sugar accumulation in different ways, as well as the volatile compounds, anthocyanin content, and fruit firmness...
February 21, 2017: Functional & Integrative Genomics
https://www.readbyqxmd.com/read/28218448/chronic-supplementation-with-dietary-proanthocyanidins-protects-from-diet-induced-intestinal-alterations-in-obese-rats
#18
Gil-Cardoso Katherine, Ginés Iris, Pinent Montserrat, Ardévol Anna, Arola Lluís, Blay Mayte, Terra Ximena
SCOPE: Increased attention has been paid to the link between altered intestinal function and elevated incidence of metabolic disorders, such as in obesity. The present study investigated in obese rats the role of grape seed proanthocyanidin extract (GSPE) chronic treatment, taken in a low, moderate or high dose, on obesity-associated intestinal alterations in response to a cafeteria diet (CAF). METHODS AND RESULTS: To evaluate the degree of intestinal inflammation, ROS production and MPO activity were measured as well as the expression of inflammatory related genes...
February 20, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28211691/lipophilized-grape-seed-proanthocyanidin-derivatives-as-novel-antioxidants
#19
Mingshun Chen, Shujuan Yu
Grape seed proanthocyanidin (GSP) is a natural food antioxidant. Natural proanthocyanidins (PC) in grape seed are usually polyhydroxy derivatives which exhibit hydrophilic character. GSP was modified structurally to improve its lipophilicity, expand its application in lipophilic media, and enhance its cellular absorption in vivo. Esterification of the water-soluble GSP was prepared by immobilized lipase Lipozyme TL IM with lauric acid, and their enhanced lipophilicity was confirmed by the 1-octanol/water partition coefficient...
February 17, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28208831/resveratrol-and-grape-extract-loaded-solid-lipid-nanoparticles-for-the-treatment-of-alzheimer-s-disease
#20
Joana A Loureiro, Stephanie Andrade, Ana Duarte, Ana Rute Neves, Joana Fontes Queiroz, Cláudia Nunes, Emmanuel Sevin, Laurence Fenart, Fabien Gosselet, Manuel A N Coelho, Maria Carmo Pereira
The aggregation of amyloid-β peptide (Aβ) has been linked to the formation of neuritic plaques, which are pathological hallmarks of Alzheimer's disease (AD). Various natural compounds have been suggested as therapeutics for AD. Among these compounds, resveratrol has aroused great interest due to its neuroprotective characteristics. Here, we provide evidence that grape skin and grape seed extracts increase the inhibition effect on Aβ aggregation. However, after intravenous injection, resveratrol is rapidly metabolized into both glucuronic acid and sulfate conjugations of the phenolic groups in the liver and intestinal epithelial cells (within less than 2 h), which are then eliminated...
February 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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