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https://www.readbyqxmd.com/read/29156067/pilot-testing-a-coaching-intervention-to-improve-certified-nursing-assistants-dressing-of-nursing-home-residents
#1
Kerry Jean Jordan, Pao-Feng Tsai, Seongkum Heo, Shasha Bai, Deborah Dailey, Cornelia K Beck, Lindsey M Butler, Rachel L Greenwood
The purpose of the current study was to identify initial effects of a coaching training intervention using Level of Assistance (LoA) strategies compared with traditional lecture techniques on the appropriateness of LoA use by certified nursing assistants (CNAs) and independence of dressing of nursing home residents with dementia. Seventeen CNA-resident dyads participated in this pilot randomized controlled trial (RCT). Control and experimental group CNAs received a 25-minute traditional lecture. Experimental group CNAs also underwent three coaching sessions over 4 weeks...
November 1, 2017: Research in Gerontological Nursing
https://www.readbyqxmd.com/read/29154560/racial-discrimination-experiences-and-african-american-youth-adjustment-the-role-of-parenting-profiles-based-on-racial-socialization-and-involved-vigilant-parenting
#2
Fatima A Varner, Yang Hou, Tajma Hodzic, Noelle M Hurd, Sheretta T Butler-Barnes, Stephanie J Rowley
OBJECTIVES: The purpose of this study was to test whether parenting profiles based on racial socialization and involved-vigilant parenting would compensate for or moderate associations between racial discrimination experiences and academic outcomes and psychological well-being among African American adolescents. METHOD: Participants were 1,363 African American adolescents (Mage = 14.19; 52.3% female) from 3 Midwestern suburban school districts. Latent profile analysis was used to examine whether there were distinct combinations of parenting...
November 20, 2017: Cultural Diversity & Ethnic Minority Psychology
https://www.readbyqxmd.com/read/29154406/promoting-resilience-among-african-american-girls-racial-identity-as-a-protective-factor
#3
Sheretta T Butler-Barnes, Seanna Leath, Amber Williams, Christy Byrd, Rona Carter, Tabbye M Chavous
This study examines school climate, racial identity beliefs, and achievement motivation beliefs within a cultural-ecological and risk and resilience framework. Data were drawn from a longitudinal study of 733 (Mage  = 14.49) African American adolescent girls. A linear mixed effects model was used to determine if racial identity dimensions moderated the relationship between school climate and achievement motivation beliefs across four waves. Results revealed that racial identity (private regard and racial centrality) and ideology (nationalist) beliefs were associated with higher achievement motivation beliefs over time, while racial centrality and private regard, and a sense of belonging served as protective factors...
November 20, 2017: Child Development
https://www.readbyqxmd.com/read/29153961/welcoming-expertise-bereaved-parents-perceptions-of-the-parent-healthcare-provider-relationship-when-a-critically-ill-child-is-admitted-to-the-paediatric-intensive-care-unit
#4
Ashleigh E Butler, Beverley Copnell, Helen Hall
BACKGROUND: Entering the paediatric intensive care unit with a critically ill child is a stressful experience for parents. In addition to fearing for their child's well-being, parents must navigate both a challenging environment and numerous new relationships with healthcare staff. How parents form relationships with staff and how they perceive both their own and the healthcare providers' roles in this early stage of their paediatric intensive care journey is currently unknown. PURPOSE: This paper explores bereaved parents' perceptions of their role and their relationships with healthcare providers when their child is admitted to the intensive care unit, as part of a larger study exploring their experiences when their child dies in intensive care...
November 15, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/29153881/relationship-of-blood-eosinophil-count-to-exacerbations-in-chronic-obstructive-pulmonary-disease
#5
Robert S Zeiger, Trung N Tran, Rebecca K Butler, Michael Schatz, Qiaowu Li, Deepak B Khatry, Ubaldo Martin, Aniket A Kawatkar, Wansu Chen
BACKGROUND: Eosinophilic airway inflammation characterizes a chronic obstructive pulmonary disease (COPD) phenotype that requires more study. OBJECTIVE: To investigate the relationship of blood eosinophil count to exacerbations in COPD. METHODS: Using administrative pharmacy and health care utilization data from 2009 to 2012, we retrospectively identified patients 40 years or older with a COPD diagnosis, postbronchodilator FEV1/forced vital capacity ratio of less than 0...
November 15, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29153162/a-100-year-review-a-century-of-change-in-temperate-grazing-dairy-systems
#6
J R Roche, D P Berry, A M Bryant, C R Burke, S T Butler, P G Dillon, D J Donaghy, B Horan, K A Macdonald, K L Macmillan
From 1917 to 2017, dairy grazing systems have evolved from uncontrolled grazing of unimproved pastures by dual-purpose dairy-beef breeds to an intensive system with a high output per unit of land from a fit-for-purpose cow. The end of World War I signaled significant government investments in agricultural research institutes around the world, which coincided with technological breakthroughs in milk harvesting and a recognition that important traits in both plants and animals could be improved upon relatively rapidly through genetic selection...
December 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29152552/chemotherapy-versus-chemoradiation-for-node-positive-bladder-cancer-practice-patterns-and-outcomes-from-the-national-cancer-data-base
#7
Waqar Haque, Vivek Verma, E Brian Butler, Bin S Teh
Background: Management of clinically node-positive bladder cancer (cN+ BC) is poorly defined; national guidelines recommend chemotherapy (CT) alone or chemoradiation (CRT). Objective: Using a large, contemporary dataset, we evaluated national practice patterns and outcomes of CT versus CRT to elucidate the optimal therapy for this patient population. Methods: The National Cancer Data Base (NCDB) was queried (2004-2013) for patients diagnosed with cTanyN1-3M0 BC...
October 27, 2017: Bladder Cancer
https://www.readbyqxmd.com/read/29152188/prey-use-by-dingoes-in-a-contested-landscape-ecosystem-service-provider-or-biodiversity-threat
#8
Damian S Morrant, Christopher M Wurster, Christopher N Johnson, James R A Butler, Bradley C Congdon
In Australia, dingoes (Canis lupus dingo) have been implicated in the decline and extinction of a number of vertebrate species. The lowland Wet Tropics of Queensland, Australia is a biologically rich area with many species of rainforest-restricted vertebrates that could be threatened by dingoes; however, the ecological impacts of dingoes in this region are poorly understood. We determined the potential threat posed by dingoes to native vertebrates in the lowland Wet Tropics using dingo scat/stomach content and stable isotope analyses of hair from dingoes and potential prey species...
November 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29151668/bulging-brains
#9
J Weickenmeier, P Saze, C A M Butler, P G Young, A Goriely, E Kuhl
Brain swelling is a serious condition associated with an accumulation of fluid inside the brain that can be caused by trauma, stroke, infection, or tumors. It increases the pressure inside the skull and reduces blood and oxygen supply. To relieve the intracranial pressure, neurosurgeons remove part of the skull and allow the swollen brain to bulge outward, a procedure known as decompressive craniectomy. Decompressive craniectomy has been preformed for more than a century; yet, its effects on the swollen brain remain poorly understood...
December 2017: Journal of Elasticity
https://www.readbyqxmd.com/read/29151634/fungal-planet-description-sheets-558-624
#10
P W Crous, M J Wingfield, T I Burgess, G E St J Hardy, P A Barber, P Alvarado, C W Barnes, P K Buchanan, M Heykoop, G Moreno, R Thangavel, S van der Spuy, A Barili, S Barrett, S O Cacciola, J F Cano-Lira, C Crane, C Decock, T B Gibertoni, J Guarro, M Guevara-Suarez, V Hubka, M Kolařík, C R S Lira, M E Ordoñez, M Padamsee, L Ryvarden, A M Soares, A M Stchigel, D A Sutton, A Vizzini, B S Weir, K Acharya, F Aloi, I G Baseia, R A Blanchette, J J Bordallo, Z Bratek, T Butler, J Cano-Canals, J R Carlavilla, J Chander, R Cheewangkoon, R H S F Cruz, M da Silva, A K Dutta, E Ercole, V Escobio, F Esteve-Raventós, J A Flores, J Gené, J S Góis, L Haines, B W Held, M Horta Jung, K Hosaka, T Jung, Ž Jurjević, V Kautman, I Kautmanova, A A Kiyashko, M Kozanek, A Kubátová, M Lafourcade, F La Spada, K P D Latha, H Madrid, E F Malysheva, P Manimohan, J L Manjón, M P Martín, M Mata, Z Merényi, A Morte, I Nagy, A-C Normand, S Paloi, N Pattison, J Pawłowska, O L Pereira, M E Petterson, B Picillo, K N A Raj, A Roberts, A Rodríguez, F J Rodríguez-Campo, M Romański, M Ruszkiewicz-Michalska, B Scanu, L Schena, M Semelbauer, R Sharma, Y S Shouche, V Silva, M Staniaszek-Kik, J B Stielow, C Tapia, P W J Taylor, M Toome-Heller, J M C Vabeikhokhei, A D van Diepeningen, N Van Hoa, Van Tri M, N P Wiederhold, M Wrzosek, J Zothanzama, J Z Groenewald
Novel species of fungi described in this study include those from various countries as follows: Australia: Banksiophoma australiensis (incl. Banksiophoma gen. nov.) on Banksia coccinea, Davidiellomycesaustraliensis (incl. Davidiellomyces gen. nov.) on Cyperaceae, Didymocyrtis banksiae on Banksia sessilis var. cygnorum, Disculoides calophyllae on Corymbia calophylla, Harknessia banksiae on Banksia sessilis, Harknessia banksiae-repens on Banksia repens, Harknessia banksiigena on Banksia sessilis var. cygnorum, Harknessia communis on Podocarpus sp...
June 2017: Persoonia
https://www.readbyqxmd.com/read/29150610/implications-of-improved-representations-of-plant-respiration-in-a-changing-climate
#11
Chris Huntingford, Owen K Atkin, Alberto Martinez-de la Torre, Lina M Mercado, Mary A Heskel, Anna B Harper, Keith J Bloomfield, Odhran S O'Sullivan, Peter B Reich, Kirk R Wythers, Ethan E Butler, Ming Chen, Kevin L Griffin, Patrick Meir, Mark G Tjoelker, Matthew H Turnbull, Stephen Sitch, Andy Wiltshire, Yadvinder Malhi
Land-atmosphere exchanges influence atmospheric CO2. Emphasis has been on describing photosynthetic CO2 uptake, but less on respiration losses. New global datasets describe upper canopy dark respiration (R d) and temperature dependencies. This allows characterisation of baseline R d, instantaneous temperature responses and longer-term thermal acclimation effects. Here we show the global implications of these parameterisations with a global gridded land model. This model aggregates R d to whole-plant respiration R p, driven with meteorological forcings spanning uncertainty across climate change models...
November 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29149833/g4-interacting-dna-helicases-and-polymerases-potential-therapeutic-targets
#12
Katrina Estep, Thomas J Butler, Jun Ding, Robert M Brosh
Guanine-rich DNA can fold into highly stable non-canonical four-stranded DNA structures called G-quadruplexes. These structures present obstacles for the DNA replication machinery, and it has been hypothesized that both eukaryotic DNA helicases and polymerases have evolved to resolve G4 DNA in vivo. Since the discovery of G-quadruplex DNA in the early 1960's, a number of studies have emerged reporting G-quadruplex DNA unfolding by helicase enzymes and DNA synthesis past G4 by specialized translesion polymerase enzymes...
November 16, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29148911/report-from-enhanced-safety-surveillance-of-two-influenza-vaccines-vaxigrip-and-intanza-15%C3%AE-g-in-two-european-countries-during-influenza-season-2016-17-and-comparison-with-2015-16-season
#13
Anne Laure Chabanon, Hélène Bricout, Céline Ballandras, Audrey Souverain, Timothy David Caroe, Karina M Butler
Passive enhanced safety surveillance (ESS) was implemented in the United Kingdom and in the Republic of Ireland for Vaxigrip and Intanza 15µg influenza vaccines during the 2016/17 influenza season. Lessons learned during 2015/16 ESS implementation were integrated and applied towards the current ESS. The primary objective was to estimate the reporting rates of suspected adverse reactions (ARs) occurring within 7 days of vaccination with Vaxigrip or Intanza 15µg. For Vaxigrip (N = 962), 17 vaccinees (1.8%) reported 59 suspected ARs (6...
November 17, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29148769/azetidine-and-piperidine-carbamates-as-efficient-covalent-inhibitors-of-monoacylglycerol-lipase
#14
Christopher R Butler, Elizabeth M Beck, Anthony R Harris, Zhen Huang, Laura A McAllister, Christopher W Am Ende, Kimberly F Fennell, Timothy L Foley, Kari R Fonseca, Steven J Hawrylik, Douglas S Johnson, John D Knafels, Scot Mente, Stephen Noell, Jayvardhan Pandit, Tracy B Phillips, Justin R Piro, Bruce N Rogers, Tarek A Samad, Jane Wang, Shuangyi Wan, Michael A Brodney
Monoacylglycerol lipase (MAGL) is the main enzyme responsible for degradation of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the CNS. MAGL catalyzes the conversion of 2-AG to arachidonic acid (AA), a precursor to the pro-inflammatory eicosannoids such as prostaglandins. Herein we describe highly efficient MAGL inhibitors, identified through a parallel medicinal chemistry approach that highlighted the improved efficiency of azetidine and piperidine-derived carbamates. The discovery and optimization of 3-substituted azetidine carbamate irreversible inhibitors of MAGL was aided by the generation of inhibitor-bound MAGL crystal structures...
November 17, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29148138/artificial-walking-technologies-to-improve-gait-in-cerebral-palsy-multichannel-neuromuscular-stimulation
#15
Jessica Rose, Katelyn Cahill-Rowley, Erin E Butler
Cerebral palsy (CP) is the most common childhood motor disability and often results in debilitating walking abnormalities, such as flexed-knee and stiff-knee gait. Current medical and surgical treatments are only partially effective in improving gait abnormalities and may cause significant muscle weakness. However, emerging artificial walking technologies, such as step-initiated, multichannel neuromuscular electrical stimulation (NMES), can substantially improve gait patterns and promote muscle strength in children with spastic CP...
November 2017: Artificial Organs
https://www.readbyqxmd.com/read/29145543/association-of-ipilimumab-with-safety-and-antitumor-activity-in-women-with-metastatic-or-recurrent-human-papillomavirus-related-cervical-carcinoma
#16
Stephanie Lheureux, Marcus O Butler, Blaise Clarke, Mihaela C Cristea, Lainie P Martin, Katia Tonkin, Gini F Fleming, Anna V Tinker, Hal W Hirte, Daliah Tsoref, Helen Mackay, Neesha C Dhani, Prafull Ghatage, Johanne Weberpals, Stephen Welch, Nhu-An Pham, Vinicius Motta, Valentin Sotov, Lisa Wang, Katherine Karakasis, Smitha Udagani, Suzanne Kamel-Reid, Howard Z Streicher, Patricia Shaw, Amit M Oza
Importance: Based on evidence of human papillomavirus (HPV)-induced immune evasion, immunotherapy may be an attractive strategy in cervical cancer. Ipilimumab is a fully humanized monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4 (CTLA-4), which acts to downregulate the T-cell immune response. Objective: To assess the safety and antitumor activity of ipilimumab in recurrent cervical cancer. Design, Setting, and Participants: A multicenter trial was designed for patients with metastatic cervical cancer (squamous cell carcinoma or adenocarcinoma) with measurable disease and progression after at least 1 line of platinum chemotherapy...
November 16, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29143495/palliative-care-in-residential-aged-care-an-overview
#17
Juliet Butler
OBJECTIVE: To measure how care needs, health and length of stay in permanent residential aged care differs by assessed need for palliative care. METHODS: On entry into permanent residential aged care, people's care needs and health conditions are assessed on the Aged Care Funding Instrument. Data for the period 2008-2009 and 2015-2016 were analysed for trends in care needs, health conditions, length of stay and separation reason across assessed need for palliative care...
November 15, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/29143416/plasma-renin-activity-response-to-aliskiren-and-clinical-outcomes-in-patients-hospitalized-for-heart-failure-the-astronaut-trial
#18
Muthiah Vaduganathan, Baljash Cheema, Erin Cleveland, Kamya Sankar, Haris Subacius, Gregg C Fonarow, Scott D Solomon, Eldrin F Lewis, Stephen J Greene, Aldo P Maggioni, Michael Böhm, Faiez Zannad, Javed Butler, Mihai Gheorghiade
AIMS: The direct renin inhibitor, aliskiren, is known to reduce plasma renin activity (PRA), but whether the efficacy of aliskiren varies based on an individual's baseline PRA in patients hospitalized for heart failure (HF) is presently unknown. We characterized the prognostic value of PRA and determined if this risk is modifiable with use of aliskiren. METHODS AND RESULTS: This pre-specified neurohormonal substudy of ASTRONAUT analysed all patients hospitalized for HF with ejection fraction (EF) ≤40% with available baseline PRA data (n = 1306, 80...
November 16, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29142765/duplication-of-19p13-3-in-11-year-old-male-patient-with-dysmorphic-features-and-intellectual-disability-a-review
#19
Irina Novikova, Paushpala Sen, Ann Manzardo, Merlin G Butler
We present a clinical report of an 11-year-old male patient with an interstitial duplication of 19p13.3 (829 kb in size) at genomic coordinates 3,804,495-4,033,722 bp (hg19) identified by chromosomal microarray analysis and review the literature from nine published reports adding knowledge regarding this chromosomal anomaly and clinical outcomes. The size of the duplication ranged from 0.83 to 8.9 Mb in the nine individuals. The young boy in our report was dysmorphic with microcephaly, abnormal craniofacial features, intellectual disability, aggression, and a heart murmur...
December 2017: Journal of Pediatric Genetics
https://www.readbyqxmd.com/read/29141623/low-uptake-of-aboriginal-interpreters-in-healthcare-exploration-of-current-use-in-australia-s-northern-territory
#20
Anna P Ralph, Anne Lowell, Jean Murphy, Tara Dias, Deborah Butler, Brian Spain, Jaquelyne T Hughes, Lauren Campbell, Barbara Bauert, Claire Salter, Kylie Tune, Alan Cass
BACKGROUND: In Australia's Northern Territory, most Aboriginal people primarily speak an Aboriginal language. Poor communication between healthcare providers and Aboriginal people results in adverse outcomes including death. This study aimed to identify remediable barriers to utilisation of Aboriginal Interpreter services at the Northern Territory's tertiary hospital, which currently manages over 25,000 Aboriginal inpatients annually. METHODS: This is a multi-method study using key stakeholder discussions, medical file audit, bookings data from the Aboriginal Interpreter Service 2000-2015 and an online cross-sectional staff survey...
November 15, 2017: BMC Health Services Research
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