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https://www.readbyqxmd.com/read/29351369/heparin-but-not-tissue-plasminogen-activator-improves-outcomes-in-dcd-liver-transplantation-in-a-porcine-model
#1
Amelia J Hessheimer, Marina Vendrell, Javier Muñoz, Ángel Ruíz, Alba Díaz, Luís Flores Sigüenza, Jorge Rodríguez Lanzilotta, Eduardo Delgado Oliver, Jose Fuster, Miquel Navasa, Juan Carlos García-Valdecasas, Pilar Taurá, Constantino Fondevila
BACKGROUND: Ischemic type biliary lesions arise most frequently after DCD liver transplantation and result in high morbidity and graft loss. Many DCD grafts are discarded out of fear for this complication. In theory, microvascular thrombi deposited during donor warm ischemia might be implicated in ITBL pathogenesis. Herein, we aim to evaluate the effects of the administration of either heparin or the fibrinolytic drug TPA as means to improve DCD liver graft quality and potentially avoid ITBL...
January 19, 2018: Liver Transplantation
https://www.readbyqxmd.com/read/29351165/the-relationship-between-maximum-pull-up-repetitions-and-first-repetition-mean-concentric-velocity
#2
George K Beckham, Joshua J Olmeda, Alexandra J Flores, Julian A Echeverry, Alexus F Campos, Steven B Kim
Mean concentric velocity (MCV) of exercise execution has been used by strength and conditioning professionals to improve exercise technique, provide accurate feedback, and predict exercise one repetition maximum. There is still limited research on velocity based training and currently only one research study on the pull-up exercise. The primary purpose of this research was to determine if the maximum number of pull-ups an individual can perform can be predicted by the MCV of a single pull-up repetition. Forty-nine healthy men and women were recruited who reported they could do at least two pull-ups...
January 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29351162/potentiation-effects-of-the-french-contrast-method-on-the-vertical-jumping-ability
#3
Joseba Andoni Hernández-Preciado, Eneko Baz, Carlos Balsalobre-Fernández, David Marchante, Jordan Santos-Concejero
This study examined the acute effects of the potentiation protocol known as French Contrast Method on the vertical jumping ability measured by a countermovement jump (CMJ). 31 athletes participated in the study (intervention group n=17 and control group n=14). The CMJ height was measured using the IOS application MyJump App 2.0 pre- and post- the French Contrast protocol, which consisted of 3 sets of isometric partial squats, drop jumps, dynamic half-squats and hurdle jumps. The CMJ height improved from its baseline values by 5...
January 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29348632/climate-degradation-and-extreme-icing-events-constrain-life-in-cold-adapted-mammals
#4
J Berger, C Hartway, A Gruzdev, M Johnson
Despite the growth in knowledge about the effects of a warming Arctic on its cold-adapted species, the mechanisms by which these changes affect animal populations remain poorly understood. Increasing temperatures, declining sea ice and altered wind and precipitation patterns all may affect the fitness and abundance of species through multiple direct and indirect pathways. Here we demonstrate previously unknown effects of rain-on-snow (ROS) events, winter precipitation, and ice tidal surges on the Arctic's largest land mammal...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29346530/bacterioplankton-composition-in-tropical-high-elevation-lakes-of-the-andean-plateau
#5
Pablo Aguilar, Cristina Dorador, Irma Vila, Ruben Sommaruga
High-elevation lakes in the tropics are subject to extreme environmental fluctuations and microbes may harbour a unique genomic repertoire, but their composition and diversity are largely unknown. Here we compared the planktonic bacterial community composition (BCC) and diversity of three tropical lakes located in the high Andean plateau (???4400 m above sea level) during the dry and wet season. Diversity in these lakes was higher in the cool and wet season than in the warm and dry one. OTUs composition was significantly different among lakes and between seasons...
January 16, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29344422/the-effects-of-physical-training-are-varied-and-occur-in-an-exercise-type-dependent-manner-in-elderly-men
#6
Mari L Sbardelotto, Giulia S Pedroso, Fernanda T Pereira, Helen R Soratto, Stella Ms Brescianini, Pauline S Effting, Anand Thirupathi, Renata T Nesi, Paulo Cl Silveira, Ricardo A Pinho
Regular exercise can decrease the deleterious effects of aging and limit the development and progression of chronic disease in elderly people, depending on the type, intensity, frequency, and duration of exercise. This study aimed to investigate the potential protective effects of different physical training programs on oxidative stress parameters and inflammatory and neurotrophic mediators in the serum of elderly men. Healthy male volunteers [60 to 80 years; n=55] were divided into four groups: control [Ctr, n=14], aerobic training on dry land [ATdl, n=12]; and combined training on dry land [CTdl, n=12] or in water [CTw, n=17]...
December 2017: Aging and Disease
https://www.readbyqxmd.com/read/29341667/dark-kinetic-heating-of-neutron-stars-and-an-infrared-window-on-wimps-simps-and-pure-higgsinos
#7
Masha Baryakhtar, Joseph Bramante, Shirley Weishi Li, Tim Linden, Nirmal Raj
We identify a largely model-independent signature of dark matter (DM) interactions with nucleons and electrons. DM in the local galactic halo, gravitationally accelerated to over half the speed of light, scatters against and deposits kinetic energy into neutron stars, heating them to infrared blackbody temperatures. The resulting radiation could potentially be detected by the James Webb Space Telescope, the Thirty Meter Telescope, or the European Extremely Large Telescope. This mechanism also produces optical emission from neutron stars in the galactic bulge, and x-ray emission near the galactic center because dark matter is denser in these regions...
September 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29340745/a-6-week-warm-up-injury-prevention-programme-results-in-minimal-biomechanical-changes-during-jump-landings-a-randomized-controlled-trial
#8
Jeffrey B Taylor, Kevin R Ford, Randy J Schmitz, Scott E Ross, Terry A Ackerman, Sandra J Shultz
PURPOSE: To examine the extent to which an ACL injury prevention programme modifies lower extremity biomechanics during single- and double-leg landing tasks in both the sagittal and frontal plane. It was hypothesized that the training programme would elicit improvements in lower extremity biomechanics, but that these improvements would be greater during a double-leg sagittal plane landing task than tasks performed on a single leg or in the frontal plane. METHODS: Ninety-seven competitive multi-directional sport athletes that competed at the middle- or high-school level were cluster randomized into intervention (n = 48, age = 15...
January 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29339655/the-impact-of-arterial-clamping-technique-in-robot-assisted-partial-nephrectomy-on-renal-function-and-surgical-outcomes-six-year-experience-at-siriraj-hospital-thailand
#9
Tawatchai Taweemonkongsap, Chalairat Suk-Ouichai, Ekkarin Chotikawanich, Siros Jitpraphai, Varat Woranisarakul, Patkawat Ramart, Kittipong Phinthusophon, Teerapon Amornvesukit, Sunai Leewansangtong, Sittiporn Srinualnad, Chaiyong Nualyong
INTRODUCTION: Robot-assisted partial nephrectomy (RAPN) with different arterial clamping techniques has increasingly been performed to avoid ischemic injury to nephron. However, postoperative renal function remains controversial. We determine the impact of each renal arterial clamping on surgical and renal outcomes after RAPN. MATERIALS AND METHODS: Patients who underwent RAPN at Siriraj Hospital from 2010 to 2016 were retrospectively reviewed and stratified into 3 cohorts: main-clamp (MAC), selective-clamp, and off-clamp...
January 16, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29338139/occurrence-of-ovarian-follicular-dominance-during-stimulation-for-ivm-impacts-usable-blastocyst-yield
#10
Sergio Romero, Ricardo Pella, Francisco Escudero, Ygor Pérez, Mario García, Patricia Orihuela
OBJECTIVE: To evaluate the influence of ovarian follicular dominance on the outcome of oocyte in-vitro maturation. METHODS: This retrospective cohort study included 21 patients with polycystic ovaries or polycystic ovary syndrome (Rotterdam criteria, 2004) subjected to 24 in-vitro maturation (IVM) cycles between October 2015 and January 2017. Patients undergoing IVM received minimal gonadotropin stimulation starting on day 2 or 3 of the cycle; ovum pick-up typically occurred on days 6 to 8...
January 17, 2018: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29337831/the-acute-effects-of-a-caffeine-containing-supplement-on-anaerobic-power-and-subjective-measurements-of-fatigue-in-recreationally-active-males
#11
Chelsea J Hahn, Andrew R Jagim, Clayton L Camic, Matthew J Andre
Studies show mixed results for the effects of caffeine on performance, warranting further investigation. The purpose of this study was to examine the acute effects of a caffeine-containing supplement on anaerobic power and subjective measurements of fatigue during resisted sprinting on males. Fourteen recreationally-active males [N=14; (mean±SD), age: 21.0±0.7 yrs., height: 178.5±5.1 cm, weight: 77.3±9.6 kg, percent body fat: 12.6±4.8%] participated in a double-blind, placebo controlled, within-subjects crossover design study...
January 4, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29331828/a-recovery-time-after-warming-restores-mitochondrial-function-and-improves-developmental-competence-of-vitrified-ovine-oocytes
#12
Sara Succu, Sergio Domenico Gadau, Elisa Serra, Angelo Zinellu, Ciriaco Carru, Cristian Porcu, Salvatore Naitana, Fiammetta Berlinguer, Giovanni Giuseppe Leoni
The aim of the present study was to assess the ability of vitrified/warmed oocyte to recover from vitrification-induced damages after warming. In vitro matured, vitrified/warmed ovine oocytes were assessed for developmental competence, mitochondrial activity and distribution, ATP, ROS and catalase levels during 6 h of in vitro culture using fresh oocytes as control. ATP content in vitrified oocytes was lower than control during 4 h of post warming culture (p < .01). Vitrified oocytes were able to fill this gap only after 6 h of post-warming incubation...
December 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/29330156/application-of-receptor-theory-to-the-design-and-use-of-fixed-proportion-mu-opioid-agonist-and-antagonist-mixtures-in-rhesus-monkeys
#13
Jeremy C Cornelissen, Samuel Obeng, Kenner C Rice, Yan Zhang, S Stevens Negus, Matthew Banks
Receptor theory predicts that fixed-proportion mixtures of a competitive, reversible agonist (e.g. fentanyl) and antagonist (e.g. naltrexone) at a common receptor (e.g. mu opioid receptors; MOR) will result in antagonist proportion-dependent decreases in apparent efficacy of the mixtures and downward shifts in mixture dose-effect functions. The present study tested this hypothesis by evaluating behavioral effects of fixed-proportion fentanyl/naltrexone mixtures in a warm-water tail-withdrawal procedure in rhesus monkeys (n=4)...
January 12, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29329188/the-impact-of-combined-warm-ischemia-time-on-development-of-acute-kidney-injury-in-donation-after-circulatory-death-liver-transplantation-stay-within-the-golden-hour
#14
Marit Kalisvaart, Andrea Schlegel, Ilaria Umbro, Jubi E de Haan, Irene Scalera, Wojciech G Polak, Jan Nm IJzermans, Darius F Mirza, M Thamara Pr Perera, John I Isaac, James Ferguson, Anna Paola Mitterhofer, Jeroen de Jonge, Paolo Muiesan
BACKGROUND: Acute kidney injury (AKI) is a common complication after liver transplantation and more frequently observed when high-risk grafts, such as DCD grafts are used. Our aim was to investigate the impact of the ischemia periods on development of AKI in DCD liver transplantation. METHODS: We performed a 2-center retrospective study with 368 DCD graft-recipients. Donor warm ischemia time (DWIT) was divided into agonal phase (withdrawal of life-support - cardiac arrest) and asystolic phase (cardiac arrest - start cold perfusion)...
January 11, 2018: Transplantation
https://www.readbyqxmd.com/read/29324576/intermittent-cooling-during-judo-training-in-a-warm-humid-environment-reduces-autonomic-and-hormonal-impact
#15
Eduardo Carballeira, José Morales, David H Fukuda, María L Granada, Vicente Carratalá-Deval, Alfonso López Díaz de Durana, Jeffrey R Stout
The purpose of this study was to identify the effects of superficial cooling on physiological responses while training in a warm, humid environment during an international judo training camp. Sixteen judokas (8 women and 8 men) participated in the experiment. Four high-level women and four men were randomly assigned to wear a cooling vest (vest group, VG) during the recovery periods within a training session (i.e. 8 bouts of 5 min fighting with 5 min rest) and up to 10 min after the session, while the remaining athletes in the control group (CG) trained without the use of any cooling aids...
January 5, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29317730/large-scale-sill-emplacement-in-brazil-as-a-trigger-for-the-end-triassic-crisis
#16
Thea H Heimdal, Henrik H Svensen, Jahandar Ramezani, Karthik Iyer, Egberto Pereira, René Rodrigues, Morgan T Jones, Sara Callegaro
The end-Triassic is characterized by one of the largest mass extinctions in the Phanerozoic, coinciding with major carbon cycle perturbations and global warming. It has been suggested that the environmental crisis is linked to widespread sill intrusions during magmatism associated with the Central Atlantic Magmatic Province (CAMP). Sub-volcanic sills are abundant in two of the largest onshore sedimentary basins in Brazil, the Amazonas and Solimões basins, where they comprise up to 20% of the stratigraphy. These basins contain extensive deposits of carbonate and evaporite, in addition to organic-rich shales and major hydrocarbon reservoirs...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29311751/measurement-and-correlation-of-the-viscosity-of-1-1-1-2-2-4-5-5-5-nonafluoro-4-trifluoromethyl-3-pentanone
#17
Chenyang Wen, Xianyang Meng, Marcia L Huber, Jiangtao Wu
The Paris Agreement on climate change, in which many nations have agreed to limit greenhouse gas emissions, has spurred interest in developing working fluids with low global warming potential (GWP) that can satisfy environmental concerns and have thermophysical properties that can meet engineering performance requirements. One such fluid is 1,1,1,2,2,4,5,5,5-nonafluoro-4-(trifluoromethyl)-3-pentanone (also known as Novec-649 and Novec-1230), which has potential applications in organic Rankine cycles (ORC), electronics cooling, computer/data center cooling and fire extinguishing...
October 12, 2017: Journal of Chemical and Engineering Data
https://www.readbyqxmd.com/read/29311110/long-lasting-in-vivo-effects-of-the-cannabinoid-cb1-antagonist-am6538
#18
Carol A Paronis, Girish R Chopda, Kiran Vemuri, Ani S Zakarian, Alexandros Makriyannis, Jack Bergman
AM6538 is a cannabinoid antagonist that binds CB1 receptors expressed in HEK-293 cells in a wash-resistant manner. The effects of AM6538 in live animals has not previously been established. We characterized the antagonist effects of AM6538 in male mice, using a warm-water tail-withdrawal assay, and in male squirrel monkeys trained to discriminate the CB1 agonist AM4054 from vehicle. The cannabinoid agonists WIN 55,212, Δ9-tetrahydrocannabinol (THC), and AM4054 all produced 100% maximum possible antinociceptive effects in mice following vehicle pretreatment...
January 8, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29310591/uncontrolled-donation-after-circulatory-death-comparison-of-two-kidney-preservation-protocols-on-graft-outcomes
#19
Claire Delsuc, Alexandre Faure, Julien Berthiller, Didier Dorez, Xavier Matillon, Vannary Meas-Yedid, Bernard Floccard, Guillaume Marcotte, Vanessa Labeye, Maud Rabeyrin, Ricardo Codas, Cécile Chauvet, Philip Robinson, Emmanuel Morelon, Lionel Badet, William Hanf, Thomas Rimmelé
BACKGROUND: Kidney transplantation following uncontrolled donation after circulatory death (uDCD) presents a high risk of delayed graft function due to prolonged warm ischemia time. In order to minimise the effects of ischemia/reperfusion injury during warm ischemia, normothermic recirculation recently replaced in situ perfusion prior to implantation in several institutions. The aim of this study was to compare these preservation methods on kidney graft outcomes. METHODS: The primary endpoint was the one-year measured graft filtration rate (mGFR)...
January 8, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29301691/do-female-reproductive-stage-and-phenotype-influence-thermal-requirements-in-an-oviparous-lizard
#20
Guadalupe López Juri, Margarita Chiaraviglio, Gabriela Cardozo
Reproduction is an energetically costly activity that can alter thermal requirements in Squamata. This phenomenon has been largely studied in many viviparous species; however, little is known about the role of oviparous females in controlling temperature during vitellogenesis and embryo development before oviposition. Diversity of female phenotypes could be associated with diversity of thermoregulatory performance, since thermal requirements are frequently influenced by body shape. Furthermore, studying the thermoregulatory behaviour is fundamental to understand how females regulate their body temperature...
January 2018: Journal of Thermal Biology
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