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PRP shot

Nayana Joshi Jubert, Luciano Rodríguez, Maria Mercedes Reverté-Vinaixa, Aurora Navarro
BACKGROUND: Intra-articular injections of platelet-rich plasma (PRP) to treat symptoms of knee osteoarthritis (OA) have been successfully used in young patients and in the early stages of disease. No previous studies have analyzed outcomes of PRP injections during the late stages. HYPOTHESIS: PRP reduces pain and leads to a more effective and lasting functional recovery than corticosteroid with local anesthetic. STUDY DESIGN: Randomized controlled trial; Level of evidence, 2...
February 2017: Orthopaedic Journal of Sports Medicine
Umit Ubeyt Inan, Onur Polat, Sibel Inan, Safiye Yigit, Zeki Baysal
PURPOSE: To compare the pain responses of patients with proliferative diabetic retinopathy (PDR) undergoing panretinal photocoagulation (PRP) using either pattern scan laser (PASCAL) or navigated laser photocoagulation (NAVILAS). METHODS: Patients diagnosed with PDR were randomly assigned to undergo either PASCAL or NAVILAS photocoagulation treatment. PRP was performed using the multi-shot mode with a spot size of 200-400 µm and a pulse duration of 30 ms to obtain a white-grayish spot on the retina...
February 2016: Arquivos Brasileiros de Oftalmologia
Bijan Forogh, Elaheh Mianehsaz, Shervan Shoaee, Tannaz Ahadi, Gholam R Raissi, Simin Sajadi
BACKGROUND: Evidence on the effect of platelet-rich plasma (PRP) in treating osteoarthritis (OA) is insufficient. Therefore, the present study compares the effects of a one-time injection of PRP and corticosteroid (CS). METHODS: In the present randomized double blind clinical trial, the participants who suffered from knee osteoarthritis (Grades II/III), were randomly divided into two groups: intra articular injection of PRP and CS. Knee injury and osteoarthritis outcome score (KOOS), the 20-Meter-Walk Test (20MW), active and passive ranges of motions (ROM), flexion contracture, and pain intensity based on Visual Analog Scale (VAS) were assessed before, 2-months, and 6-months after interventions...
July 2016: Journal of Sports Medicine and Physical Fitness
Max-Joseph Kraus, Erwin F Strasser, Reinhold Eckstein
BACKGROUND: Platelet shape change is a dynamic process that has been classified in different types. Exact documentation of platelet structure needs an improved method of measuring platelet shape. METHODS: 10 μl of platelet-rich plasma (PRP) from anticoagulated whole blood (3.2% buffered sodium citrate 0.105 mol/l) was put onto a glass slide covered with a cover slip. By use a of dark field light microscope connected with a CMOS-Camera a photographic snap-shot was taken after 5 and 30 min. Diameter of platelets and length of filopodia were measured with a self-developed plugin for ImageJ software...
2010: Transfusion Medicine and Hemotherapy
Chiaki Miyazaki
Haemophilus influenzae type b (Hib) is the most common cause of bacterial meningitis among children. Hib conjugate vaccines, capsule polysaccharide (polyribosylribitol phosphate: PRP) conjugated with carrier protein, are very effective and safe. Hib vaccine conjugated with tetanus toxoid (PRP-T: ActHIB) was licensed in 1992 in France. After introduction of Hib vaccines among young infants routinely, the incidence of Hib meningitis dramatically decreased in many countries. In Japan, according to two prospective studies for bacterial meningitis in 1996-98, 8...
October 2008: Nihon Rinsho. Japanese Journal of Clinical Medicine
H Shams, I Heron
Immunogenicity and vaccine potency of carrier proteins of two different PRP-tetanus toxoid (PRP-T) conjugated vaccines, produced using different size PRP (Act-Hib & Amvax Hib-T), and one PRP-CRM197 (Hib-TITER) were studied. The immunogenicity and the vaccine potency of the carrier component of the tested PRP-conjugated vaccines, and their influences on the potency of the tetanus toxoid (T) and of the diphtheria toxoid (D) component of diphtheria toxoid-tetanus toxoid-acellular pertussis-inactivated polio vaccine (DTaP-IPV) were variable...
May 1998: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
G W Fischer, M G Ottolini, J J Mond
Maternal and neonatal vaccine strategies have been used successfully throughout the world for many years. In addition, new vaccine technologies are likely to overcome the scientific issues related to safety, immunogenicity, and efficacy of neonatal vaccines. There are obvious advantages to maternal or neonatal immunizations. Immunologic protection in the first 8 to 12 weeks of life occurs only by passive immunization with IgG or by actively immunizing the mother or newborn baby (or by doing both as in hepatitis B)...
March 1997: Clinics in Perinatology
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