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https://www.readbyqxmd.com/read/29898772/the-impact-of-bariatric-surgery-on-the-resolution-of-obstructive-sleep-apnoea
#1
Toritseju Oluwafunmilayo Sillo, Simon Lloyd-Owen, Emma White, Karen Abolghasemi-Malekabadi, Penny Lock-Pullan, Muhammed Ali, Anthony Perry, Steven John Robinson, Martin Stuart Wadley
OBJECTIVE: Obesity is associated with a high incidence of obstructive sleep apnoea (OSA). Bariatric surgery is postulated to lead to OSA resolution, but there is inconclusive evidence on its efficacy. We used objective measurements to determine the rate of resolution or improvement of OSA in patients who had bariatric procedures in our unit. RESULTS: Data was analysed on all patients with OSA who underwent bariatric procedures [laparoscopic Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG)] between June 2012 and September 2016 in our unit...
June 14, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29892042/sleep-disordered-breathing-circulating-exosomes-and-insulin-sensitivity-in-adipocytes
#2
Abdelnaby Khalyfa, David Gozal, Juan F Masa, José Maria Marin, Zhuanghong Qiao, Jaime Corral, Mónica González, Sergi Marti, Leila Kheirandish-Gozal, Carlos Egea, M-Ángeles Sánchez-Quiroga, Francisco J Gómez de Terreros, F Javier Barca
BACKGROUND: Sleep-disordered-breathing (SDB), which is characterized by chronic intermittent hypoxia (IH) and sleep fragmentation (SF), is a prevalent condition that promotes metabolic dysfunction, particularly among patients suffering from obstructive hypoventilation syndrome (OHS). Exosomes are generated ubiquitously, are readily present in the circulation, and their cargo may exert substantial functional cellular alterations in both physiological and pathological conditions. However, the effects of plasma exosomes on adipocyte metabolism in patients with OHS or in mice subjected to IH or SF mimicking SDB are unclear...
June 11, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29886648/-a-cross-sectional-survey-of-treatment-acceptance-and-influence-factors-in-patients-with-obstructive-sleep-apnea
#3
B X Chen, Q Ou, M X Pan
Objective: To investigate the treatment acceptance in patients with obstructive sleep apnea (OSA) and its influence factors. Methods: This cross-sectional survey recruited OSA patients diagnosed at sleep center in Guangdong General Hospital from January 2014 to December 2015. By phone follow-up, a pre-designed questionnaire was performed for all adults, which composed of the following sections: treatment or none, treatment method, reason for non-treatment, revisit or none. Results: From 524 OSA patients with completed contact information, 480 (91...
May 29, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29880147/the-scope-of-sleep-problems-in-canadian-children-and-adolescents-with-obesity
#4
Joanna E MacLean, Kristie DeHaan, Tamya Chowdhury, Joy Nehme, Glenda N Bendiak, Lynda Hoey, Linda Horwood, Hans Pasterkamp, Valerie Kirk, Evelyn Constantin, Sherri L Katz
OBJECTIVE: To determine the scope of sleep concerns, clinical features, and polysomnography (PSG) results and to identify factors that predict obstructive sleep apnea (OSA) in a cohort of children with obesity. METHODS: The study was a multicenter retrospective chart review. Data were collected from three pediatric sleep laboratories over a two year period for all children of age 8-16 years with a body mass index [BMI] ≥95th centile who were undergoing PSG. Data sources included clinical charts and PSG results...
July 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29870156/diabetes-remission-and-relapse-after-metabolic-surgery
#5
EDITORIAL
Xiaoping Chen, Xiaomu Kong
Obesity and type 2 diabetes mellitus are prevalent all over the world. Obese patients with more visceral fat are more likely to suffer from type 2 diabetes mellitus, hypertension, dyslipidemia and obstructive sleep apnea. Obese patients with type 2 diabetes mellitus have higher risk of obesity and diabetes related complications (especially arteriosclerotic cardiovascular disease). This article is protected by copyright. All rights reserved.
June 5, 2018: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/29863319/hypertension-update-resistant-hypertension
#6
Anthony J Viera
Resistant hypertension is a blood pressure (BP) level that remains above the goal level despite adherence to at least three appropriately dosed antihypertensive drugs of different classes, one of which is a diuretic. Evaluation of suspected resistant hypertension starts with confirming adherence to the drug regimen. White coat hypertension should be ruled out with out-of-office BP level measurements, ideally using 24-hour ambulatory BP monitoring. Obesity, significant alcohol intake, and interfering drugs and other substances can contribute to resistant hypertension...
June 2018: FP Essentials
https://www.readbyqxmd.com/read/29862666/inflammation-and-asthma-control-in-children-with-comorbid-obstructive-sleep-apnea
#7
Valerie E Rogers, Mary E Bollinger, Mohan E Tulapurkar, Shijun Zhu, Jeffrey D Hasday, Kevin D Pereira, Steven M Scharf
OBJECTIVES: A bi-directional relationship exists between asthma and obstructive sleep apnea (OSA) in which presence of one is associated with increased prevalence and severity of the other. Our objective was to determine whether OSA accounted for differences in airway and systemic inflammation in asthmatic children and whether inflammation was associated with asthma control. We hypothesized that greater severity of SDB would correlate with increased upper airway and systemic inflammation and result in reduced asthma control...
June 3, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29843671/insomnia-and-depressive-symptoms-in-relation-to-unhealthy-eating-behaviors-in-bariatric-surgery-candidates
#8
Małgorzata Wrzosek, Marcin Wojnar, Ada Sawicka, Marek Tałałaj, Grażyna Nowicka
BACKGROUND: Alongside obesity, insomnia and depression are common public health problems. Sleep problems are currently believed to be associated with excessive food intake and metabolic disturbances. Therefore, we aimed to explore a relationship between insomnia, depressive symptoms and eating habits as well as metabolic parameters in bariatric surgery candidates. METHODS: A total of 361 unrelated obese subjects were included in this study. Severity of sleep problems was measured with Athens Insomnia Scale (AIS) and the severity of depressive symptoms was assessed with the Beck Depression Inventory (BDI-II)...
May 29, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29808980/pericardial-effusion-in-obstructive-sleep-apnea-without-pulmonary-arterial-hypertension-and-daily-hypoxemia-is-it-unusual
#9
Emil Ivanov Manov, Ventsislava Pencheva Pencheva, Nikolay Margaritov Runev, Stefan Naydenov Naydenov, Daniela Stoychkova Petrova, Ognian Borisov Georgiev
Background: Pericardial effusion in chronic hypoxemic lung diseases, such as Obstructive Sleep Apnea syndrome, usually occurs after the development of severe pulmonary arterial hypertension. However, data about the frequency of pericardial effusions in Obstructive Sleep Apnea syndrome without pulmonary arterial hypertension and/or daytime hypoxemia are still scarce, and their pathogenesis is unclear. Aims: To assess the prevalence of pericardial effusions and their volume and location in patients with obesity and Obstructive Sleep Apnea syndrome without pulmonary arterial hypertension and/or hypoxemia...
May 29, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29804216/oxidative-stress-in-obese-children-and-adolescents-with-and-without-type-2-diabetes-mellitus-is-not-associated-with-obstructive-sleep-apnea
#10
Riva Tauman, Shlomit Shalitin, Lena Lavie
PURPOSE: Obesity, obstructive sleep apnea (OSA), and type 2 diabetes mellitus (T2DM) are associated with chronic low-grade inflammation and oxidative stress. In adults, increased lipid peroxidation, a marker of oxidative stress, was found in both metabolic syndrome and OSA. Studies on oxidative stress in children with T2DM and OSA are scarce. METHODS: Plasma oxidized low-density lipoprotein (Ox-LDL) levels were evaluated in obese children and adolescents with/without T2DM, and the contribution of OSA to oxidative stress was investigated...
May 26, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29803366/complications-associated-with-surgical-treatment-of-sleep-disordered-breathing-among-hospitalized-u-s-adults
#11
Hind A Beydoun, May A Beydoun, Hong Cheng, Anjum Khan, Shaker M Eid, Carolina Alvarez-Garriga, Colin Anderson-Smits, Alan B Zonderman, Danica Marinac-Dabic
The purpose of this cross-sectional study is to examine the relationship between surgical treatments for sleep-disordered breathing (SDB) and composite measure of surgical complications in a nationally representative sample of hospital discharges among U.S. adults. We performed secondary analyses of 33,679 hospital discharges from the 2002-2012 Nationwide Inpatient Sample that corresponded to U.S. adults (≥18 years) who were free of head-and-neck neoplasms, were diagnosed with SDB and had undergone at least one of seven procedures...
May 24, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29802398/obstructive-sleep-apnoea-is-associated-with-progression-of-arterial-stiffness-independent-of-obesity-in-participants-without-hypertension-a-koges-prospective-cohort-study
#12
Jinkwan Kim, Seung Ku Lee, Dae Wui Yoon, Chol Shin
Accumulating evidence shows that obstructive sleep apnoea (OSA) is associated with an increased risk of cardiovascular disease. However, there are no published prospective studies on the relationship between OSA and the progression of arterial stiffness. We hypothesised that OSA would increase the risk of arterial stiffness progression, independent of obesity. In the present large cohort study, 1921 participants were randomly selected and underwent polysomnography. The brachial ankle pulse wave velocity (baPWV) was measured at baseline and during the follow-period using a standard protocol...
May 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29801027/association-of-obstructive-sleep-apnea-with-calvarial-and-skull-base-thinning
#13
Cyrus Rabbani, Mohamad Z Saltagi, Michael J Ye, Janaki M Patel, Shalini Manchanda, Rick F Nelson
Importance: Spontaneous cerebrospinal fluid leaks (sCSF-L) of the temporal bone are associated with obesity, calvarial thinning, and obstructive sleep apnea (OSA), and the incidence has doubled in the past decade. It is currently unknown if OSA is independently associated with skull thinning. Objective: To determine if patients with OSA have thinner skulls than patients without OSA. Design, Setting, and Participants: A retrospective cohort study of patients who underwent a level 1 polysomnogram (PSG) and also had high-resolution computed tomographic (CT) imaging of the head from January 2010 to March 2017 at Indiana University was carried out...
May 3, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29798125/-relationship-of-symptoms-with-sleep-stage-abnormalities-in-obstructive-sleep-apnea-hypopnea-syndrome
#14
H J Liu, N Zhao, A F Zhang
Objective: To study the relationship between symptoms and sleep staging in OSAHS patients. Method: A cross-sectional study. Adult subjects who attended a sleep laboratory for diagnostic polysomnography for a period of 1 month were recruited consecutively.OSAHS was diagnosed using American Academy of Sleep Medicine criteria.Subjects filled a questionnaire for symptoms prior to polysomnography. Result: Thirty subjects, of whom 83.3% were obese, met diagnostic criteria, with males constituting 46.7% and females constituting 53%...
November 5, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29797800/sleeping-well-trial-increasing-the-effectiveness-of-treatment-with-continuous-positive-airway-pressure-using-a-weight-management-program-in-overweight-adults-with-obstructive-sleep-apnoea-a-stepped-wedge-randomised-trial-protocol
#15
Helen Truby, Bradley A Edwards, Denise M O'Driscoll, Alan Young, Ladan Ghazi, Claire Bristow, Kerryn Roem, Maxine P Bonham, Chiara Murgia, Kaitlin Day, Terry P Haines, Garun S Hamilton
BACKGROUND: The majority of adults diagnosed with obstructive sleep apnoea (OSA) are overweight or obese. Continuous positive airway pressure (CPAP) is the most common effective therapy for OSA. However, adherence declines over time with only 50% of patients prescribed CPAP continuing to use it long term. Furthermore, a recent prospective analysis indicated that those more adherent with CPAP therapy have enhanced weight gain trajectories which in turn may negatively impact their OSA. AIM: The Sleeping Well Trial aims to establish whether the timing of starting a lifestyle weight loss intervention impacts on weight trajectory in those with moderate-severe OSA treated at home with CPAP, while testing the potential for smart phone technology to improve adherence with lifestyle interventions...
May 24, 2018: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29797754/change-in-weight-and-central-obesity-by-positive-airway-pressure-treatment-in-obstructive-sleep-apnea-patients-longitudinal-data-from-the-esada-cohort
#16
Ozen K Basoglu, Ding Zou, Mehmet S Tasbakan, Jan Hedner, Silke Ryan, Johan Verbraecken, Pierre Escourrou, Ulla Antalainen, John A Kvamme, Maria R Bonsignore, Sofia Schiza, Ludger Grote
The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort. Patients with obstructive sleep apnea with positive airway pressure treatment from the European Sleep Apnea Database registry (n = 1,415, 77% male, age 54 ± 11 [mean ± SD] years, body mass index 31.7 ± 6.4 kg/m2 , apnea-hypopnea index 37 ± 24 n per hr, Epworth Sleepiness Scale 10...
May 24, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29796330/combined-surgical-approach-for-obstructive-sleep-apnea-patient
#17
Mahmoud A K Ebrahim, Osamah AlSanea, Abdulmohsen E Al-Terki
Obstructive sleep apnea (OSA) is a disease that is associated with high morbidity and mortality and can significantly impact the quality of life in a patient. OSA is strongly associated with obesity, and literature showed that weight loss will lead to improvement in OSA. The gold standard treatment for OSA is continuous positive airway pressure (CPAP). However, other methods of treatment are available. One of these methods is multilevel sleep surgery (MLS). Literature showed that bariatric surgery can also improve OSA...
2018: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/29792853/preoperative-obstructive-sleep-apnea-screening-in-gynecologic-oncology-patients
#18
Ross F Harrison, Erin E Medlin, Chase B Petersen, Stephen L Rose, Ellen M Hartenbach, David M Kushner, Ryan J Spencer, Laurel W Rice, Ahmed N Al-Niaimi
BACKGROUND: Women with a gynecologic cancer tend to be older, obese, and postmenopausal, characteristics that are associated with an increased risk for obstructive sleep apnea. However, there is limited investigation regarding the condition's prevalence in this population or its impact on postoperative outcomes. In other surgical populations, patients with obstructive sleep apnea have been observed to be at increased risk for adverse postoperative events. OBJECTIVES: To estimate the prevalence of obstructive sleep apnea among gynecologic oncology patients undergoing elective surgery and to investigate for a relationship between obstructive sleep apnea and postoperative outcomes...
May 21, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29788220/obstructive-sleep-apnea-syndrome-and-metabolic-diseases
#19
Min Li, Xiaoying Li, Yan Lu
With the rapid changes of lifestyle in modern society, including high nutritional intake and reduced physical activity, the incidence of metabolic diseases is increasing year by year. Obstructive sleep apnea syndrome (OSAS) is a sleep disorder, usually characterized by sudden pauses of breathing during sleep with interrupted sleep rhythm. Although the pathological mechanism remains poorly understood, it is strongly associated with metabolic diseases, including obesity, insulin resistance, type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD)...
May 18, 2018: Endocrinology
https://www.readbyqxmd.com/read/29786596/-coexistence-of-asthma-and-obstructive-sleep-apnea-syndrome-review-of-the-literature
#20
Magdalena Pawelec-Winiarz, Anna Brzecka
Both asthma and obstructive sleep apnea (OSA) syndrome are frequent diseases and their coexistence may implicate important consequences. The incidence of OSA syndrome among the patients with asthma is higher than in the general population, especially in the patients with nocturnal symptoms persisting despite treatment, in patients frequently admitted to hospital because of the exacerbations of asthma, and in obese patients. The causes of frequent coexistence of asthma and OSA syndrome are not fully elucidated...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
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