Giuseppe Marino, Tommaso Grassi, Elena De Ponti, Serena Negri, Filippo Testa, Daniela Giuliani, Martina Delle Marchette, Cristina Dell'Oro, Diletta Fumagalli, Gianluca Donatiello, Giulia Besana, Liliana Marchetta, Cristina Maria Bonazzi, Andrea Alberto Lissoni, Fabio Landoni, Robert Fruscio
OBJECTIVE: Immature teratomas are rare malignant ovarian germ cell tumours, typically diagnosed in young women, where fertility-sparing surgery is the treatment of choice. The role of adjuvant chemotherapy in stage I disease remains controversial. We evaluated the impact of surveillance versus chemotherapy on the recurrence rate in stage I immature teratomas. METHODS: We collected a single centre retrospective series of patients with stage I immature teratomas treated with fertility-sparing surgery at San Gerardo Hospital, Monza, Italy, between 1980 and 2019...
2024: Frontiers in Oncology